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Hokkaido University


Mapping the migration of house shrews

Researchers analyzed DNA sequences from 169 house shrews to uncover their genetic origins and migration routes. The study suggests that people traded on a larger scale than previously thought, with species from Asia and Africa showing similar genetic traits despite geographical distance.

SourceHokkaido University·JournalMammal Study·DateJan 23, 2017

Stabilizing evolutionary forces keep ants strong

Researchers found evidence of stabilizing selection that maintains functional characteristics in ant populations. The study revealed significant genetic differences and limited gene flow among ant populations, suggesting that natural selection acts on important traits while less critical traits diversify over time.

SourceHokkaido University·JournalScientific Reports·DateDec 20, 2016

The gene of autumn colors

Hokkaido University researchers have identified a key enzyme involved in chlorophyll degradation and the formation of autumn colors. By understanding this process, scientists may uncover novel mechanisms for photosynthesis and discover new enzymes with potential applications.

SourceHokkaido University·JournalThe Plant Cell·DateOct 25, 2016

Why is skin thick on the soles of the feet?

Researchers at Hokkaido University have developed a new method for capturing high-resolution, three-dimensional images of the deep structure of skin in living mice. The study reveals that basal cells divide obliquely in thicker skin and parallel in thinner skin, contributing to the maintenance of epidermis thickness

SourceHokkaido University·JournalPLOS ONE·DateOct 17, 2016

Cold medicine could stop cancer spread

Researchers at Hokkaido University discovered that a nonsteroid anti-inflammatory drug used for treating colds can suppress the spread of bladder cancers and reduce chemoresistance in mice. The study identified the metabolic enzyme aldo-keto reductase 1C1 (AKR1C1) as a key player in cancer progression.

SourceHokkaido University·JournalScientific Reports·DateOct 17, 2016

The origins of Cuban species

A research team from Hokkaido University suggests the Cuban solenodon family evolved around 59 million years ago, long after the dinosaur extinction. The species diverged from its ancestor and then traveled to Cuba via water, contradicting earlier theories.

SourceHokkaido University·JournalScientific Reports·DateAug 24, 2016

Hawaiian fruit flies had multiple ancestors

Researchers found that Hawaiian drosophilids had plural continental ancestors, independently migrating to Hawaii at different times. The team discovered 11 non-Hawaiian Scaptomyza species and reconstructed their phylogeny, estimating ancestral distributions and divergence times.

SourceHokkaido University·JournalEntomological Science·DateAug 18, 2016

Genetic influence in juvenile songbird babblings

A study by Hokkaido University researchers found that juvenile songbirds exhibit familial differences in their earliest vocal babblings, suggesting a possible genetic basis for these variations. The findings reveal that the variations are more pronounced among different families and persist even when deafened.

SourceHokkaido University·JournalScientific Reports·DateAug 17, 2016

Unraveling the jaw-dropping goblin shark

Researchers at Hokkaido University analyzed footage of goblin sharks capturing prey using a high-speed jaw projection, called 'slingshot feeding', which propels the jaws at speeds of up to 3.1 meters per second. This adaptation allows the shark to compensate for its slow swimming speed in deep-sea environments where food is scarce.

SourceHokkaido University·JournalScientific Reports·DateAug 10, 2016

Putting the pressure on platinum

Hokkaido University researchers have synthesized a platinum-based superconducting material with unique crystal structure, which becomes superconducting at 10 GPa but returns to non-superconductive state at 15 GPa. The high-pressure synthesis method holds promise for further exploration of unknown phases in various materials.

SourceHokkaido University·JournalJournal of the American Chemical Society·DateAug 5, 2016

Why apnea patients are prone to suffer from glaucoma

Scientists at Hokkaido University measured eye pressure in sleeping patients with obstructive sleep apnea syndrome for the first time, discovering an unexpected correlation between the two conditions. This study sheds light on the potential mechanisms underlying glaucoma development in patients with OSAS.

SourceHokkaido University·JournalInvestigative Ophthalmology & Visual Science·DateJul 21, 2016

A new key to understanding molecular evolution in space

Researchers at Hokkaido University have discovered a key to understanding molecular evolution in space by revealing the temperature-dependent energy-state conversion of molecular hydrogen on ice surfaces. This finding challenges existing theories and opens new horizons for studying molecular formation and evolution.

SourceHokkaido University·JournalPhysical Review Letters·DateJul 21, 2016

Bonding to bones strongly

Researchers at Hokkaido University have developed a new kind of hydrogel that bonds spontaneously and strongly to defected bones. The gel overcomes the problem of bonding with other surfaces by adding hydroxyapatite to its surface.

SourceHokkaido University·JournalAdvanced Materials·DateJul 14, 2016

A 'key' to metastasis formation

Researchers at Hokkaido University found that biglycan molecule attracts tumor cells to blood vessel walls, facilitating metastasis formation. High biglycan expression linked to poor prognosis in breast, lung, and colorectal cancer patients.

SourceHokkaido University·JournalScientific Reports·DateJul 13, 2016

On the path toward molecular robots

Researchers at Hokkaido University have created light-powered molecular motors that repetitively bend and unbend, bringing us closer to molecular robots. The development enables complex tasks and autonomous chemical reactions, which may lead to applications in medicine and other fields.

SourceHokkaido University·JournalAngewandte Chemie International Edition·DateJul 6, 2016

Unraveling the genes for sexual traits in stag beetles

Researchers built a gene expression database of a stag beetle species and identified key genes involved in sex determination and differentiation. The study found that the intersex gene plays a crucial role in determining female-specific traits, while the transformer-2 gene affects more than just sex-specific characteristics.

SourceHokkaido University·JournalBMC Genomics·DateJul 3, 2016

When suppressing immunity is a good thing

A team of researchers from Hokkaido University found that a receptor, known for its role in mediating dioxin toxicity, also regulates the body's innate immune response to viral infections. The activation of this receptor negatively regulates the production of an antiviral protein called type I interferon.

SourceHokkaido University·JournalNature Immunology·DateJul 1, 2016

Unsilencing silenced genes by CRISPR/Cas9

Scientists at Hokkaido University developed a new CRISPR/Cas9 technique to unleash silenced genes, changing cell fates. They used DNA repair mechanism MMEJ with CRISPR/Cas9 to replace off-switches with on-switches, enabling efficient gene expression in cultured cells.

SourceHokkaido University·JournalAngewandte Chemie International Edition·DateJun 30, 2016

The switch that could double USB memory

Researchers created a new method to switch strontium cobalt oxide between an insulating state and a metal magnet state at room temperature, enabling double the storage capacity of conventional USB flash drives. This technology could increase mobile phone storage by storing more photos and videos.

SourceHokkaido University·JournalAdvanced Electronic Materials·DateJun 30, 2016

Treating diseases at their origin

Scientists at Hokkaido University found that ARL3 facilitates STAT3 transport into the nucleus, regulating gene expression and cell proliferation. This discovery offers promising candidates for novel therapies targeting STAT3-related diseases.

SourceHokkaido University·JournalJournal of Biological Chemistry·DateJun 30, 2016

Unlocking the secrets of nerve regeneration

Researchers discovered that cutting parallel fibres in normal mice results in three distinct phases of degeneration, hypertrophy, and remodelling. In contrast, mice lacking the GluD2 receptor remain stuck in the degenerative phase. This suggests that GluD2 plays a crucial role in regulating nerve regeneration.

Watching the luminescent gene switch

Researchers from Hokkaido University developed a new method to track the switching on and off of circadian genes in freely moving mice, enabling the monitoring of gene expression patterns in specific tissues. This technique has significant implications for understanding clock gene function and its effects on mouse behavior.

SourceHokkaido University·JournalNature Communications·DateJun 20, 2016

Predicting the spread of the Zika virus

A new tool by Japanese researchers predicts the risk of Zika virus importation and local transmission for 189 countries, identifying subtropical and tropical nations as high-risk. Countries with a history of dengue and other mosquito-borne diseases face the greatest risk of infection.

SourceHokkaido University·JournalPeerJ·DateMay 27, 2016

Closer to the source of the itch

Researchers found that IL-17A stimulates skin cells to express genes maintaining an inflammatory microenvironment, leading to psoriasis. The study identified NFKBIZ gene as playing a significant role in the IL-17A pathway.

SourceHokkaido University·JournalInternational Immunology·DateMay 25, 2016

Making electronics safer with perovskites

Researchers at Hokkaido University are developing perovskite ceramic capacitors with improved insulating properties. The process involves sintering and annealing the material to exhibit ferroelectricity, a promising dielectric property for multi-layered ceramic capacitors.

SourceHokkaido University·JournalChemistry of Materials·DateMar 16, 2016