Researchers developed CL-iSCAT Microscope to visualize cargo trafficking in living cells, revealing traffic jams and collective migration. The technology enables real-time observation of millions of cargos, deepening understanding of cellular biology and potential medical discovery.
A newly developed labeling method allows for visualization of intraregional synaptic connections between inhibitory interneurons and excitatory engram cells. Researchers have identified the role of inhibitory interneurons in memory expression, suggesting that they suppress fear expression by inhibiting fear engram cells.
Researchers have developed a novel chloride-based solid electrolyte with exceptional ionic conductivity, addressing material limitations that hindered previous attempts. This breakthrough is expected to pave the way for commercialization of solid-state batteries, promising improved affordability and safety.
Researchers from the Institute for Basic Science developed a novel approach to healing muscle injury using conductive hydrogels and robot-assisted rehabilitation. The injectable tissue prosthesis enhances gait in rodent models without nerve stimulation, while improving long-term muscle tissue regeneration.
Researchers developed a ceria nanoparticle-immobilized mesenchymal stem cell nanovesicle hybrid system to treat rheumatoid arthritis. This approach provides both immediate pain relief through ROS scavenging and long-term immune tolerance by delivering immunomodulatory cytokines.
Researchers found that changing the stacking order of layers in transition metal dichalcogenide (TMD) semiconductors creates new optoelectronic devices with tailor-made properties. The study reveals dark excitons exclusively located in the top layer, which can be utilized for optical power switches in solar panels.
Researchers at IBS Center for Quantum Nanoscience created a novel electron-spin qubit platform assembled atom-by-atom on a surface, demonstrating ability to control multiple qubits. This breakthrough enables application of single-, two-, and three-qubit gates.
A groundbreaking review paper reveals the importance of GABA tone, the amount of GABA that regulates continuous signaling in the brain. The study identifies key mechanisms and functions, including astrocytes' role in regulating GABA tone and its impact on cognitive processes.
Scientists have successfully fabricated centimeter-scale transition metal dichalcogenide field-effect transistors with low ohmic contact resistance close to the quantum limit. The devices exhibited an ultrahigh current on/off ratio of ~10^11 at 15 K, outperforming previous values.
Researchers have identified a cluster of neurons in the hypothalamus called GABRA5 that regulates energy expenditure. Astrocytes control this cluster, producing tonic GABA that inhibits it, leading to weight gain.
Researchers have made a significant advancement in the synthesis of β-lactam scaffolds, structural components frequently found in essential antibiotics. The breakthrough uses nickel catalysts to overcome challenges in β-lactam synthesis, enabling more efficient and simplified production of high-value materials.
A new study found that a massive North Atlantic cooling event led to the disruption of early human occupation in Europe, with climate stress changing the course of early human history. The study used observational and modeling evidence to document the unprecedented climate anomaly.
A team of researchers has discovered a way to harness random telegraph noises in semiconductors, generating high-amplitude signals and manifesting inherent quantum states. By introducing vanadium into tungsten diselenide, they created a device that can switch between two stable states using voltage polarity.
A recent study reveals that past climate changes and vegetation shifts played a key role in determining when and where early human species interbred. The research suggests that the overlap of habitats led to increased encounters and interactions among groups, increasing the chance of interbreeding.
Researchers have discovered a way to utilize nonlinear scattering media for optical computing and machine learning. They created a novel theoretical framework involving third-order tensors, which can represent the complex relationships between input and output signals. This breakthrough has potential applications in real-world settings...
GOBI overcomes model-free and model-based inference method limitations by introducing an easily testable condition for a general monotonic ODE model to reproduce time-series data. It successfully infers positive and negative regulations in various networks, distinguishing between direct and indirect causation.
Researchers used X-ray photocrystallography to study the transition metal-nitrenoid intermediate in catalytic amination reactions. The team successfully captured the structure and properties of the rhodium-acylnitrenoid intermediate, providing crucial insights into its reactivity.
The study reveals that quantum thermal machines exhibit distinct synchronization behavior, with cooperation and competition emerging among different components. The researchers found that cooperation manifests in harmony-like synchrony, while competition thrives in chaotic conditions.
The IBS-KAI Conference will focus on viral diseases and immunology, featuring over 20 international experts. The conference aims to prepare for responses to future infectious diseases, including those with pandemic potentials.
A team of scientists identified the dorsal medial prefrontal cortex as a key region in predicting rumination, which is linked to depression. The study's findings suggest that dynamic connectivity between brain regions can be used to decode rumination patterns.
The 2023 International Venus Observation Campaign aims to characterize the planet's atmosphere near the cloud-top level from three locations in the solar system. Key findings include the discovery of unknown UV absorbers in the upper clouds, which will be studied using data from JAXA's Akatsuki orbiter and ground-based telescopes.
Researchers at the Institute for Basic Science have identified specific neurons in the hippocampus that allow us to recognize individual social counterparts and update their value through interactions. The dorsal CA1 region plays a crucial role in this process, enabling long-term memories of individuals to be formed.
A team of researchers discovered a new phenomenon, 'cavity-momentum locking', which allows precise control over quantum scar states in photonic crystals. This breakthrough has significant implications for quantum information, communication, and optoelectronic devices.
Researchers discovered that MSH2-MSH3 plays a crucial role in selecting the right DNA repair process by interacting with other proteins during DSB repair. This interaction facilitates error-free homologous recombination and blocks error-prone polymerase theta-mediated end-joining.
A new study found that early human ancestors adapted to diverse food resources and mosaic landscapes, which increased their resilience to climate changes. The researchers analyzed over 3,000 fossil specimens and archeological sites, revealing a preference for biomes with high plant and animal diversity.
Researchers have developed a novel method for recycling valuable metals from spent lithium-ion batteries using spinning reactors. This technology simplifies the extraction-stripping process, allowing for rapid separation of metals in minutes with low concentrations of extractants.
A new type of floatable photocatalytic platform composed of hydrogel nanocomposites efficiently proceeds hydrogen evolution reaction. The platform exhibits clear advantages over conventional systems, including efficient solar energy conversion and easy gas diffusion.
Researchers discovered that parvalbumin interneurons secrete substance P, driving slow vasodilation and increasing blood flow in the brain. This process allows for waste removal and prevention of neurological dysfunctions like dementia.
Researchers developed a new imaging technique that visualizes the interaction between reactive astrocytes and neurons in the brain, revealing a potential breakthrough in Alzheimer's disease diagnosis and treatment. The study found that acetate promotes reactive astrogliosis, leading to dementia, and offers a new target for AD treatment.
A recent study reveals that uneven future warming in the Indian Ocean can cause shifts in monsoon precipitation, with potential impacts on societies and ecosystems. The research identifies key mechanisms driving these changes, including winds and ocean currents.
Scientists discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy. DNA polymerase θ (POLQ) is an important factor in repairing complex DNA double-strand breaks, and inhibiting POLQ may augment the efficacy of heavy ion radiation therapy.
A South Korean research team has successfully searched for Dine-Fischler-Srednicki-Zhitnitskii (DFSZ) axion dark matter using a new experimental setup. The group achieved a higher sensitivity than existing experiments, excluding axion dark matter around 4.55 µeV at DFSZ sensitivity.
A novel method has been developed to produce platinum-based alloy nanoparticles for efficient hydrogen fuel cells. The nanocatalysts exhibit enhanced power performance and stability, with high specific rated power of 5.9 kW/g Pt, surpassing 2025 targets set by the U.S. Department of Energy.
A new study warns that an irreversible loss of West Antarctic and Greenland ice sheets may be imminent if global temperature change cannot be stabilized below 1.8°C, leading to rapid sea level rise.
Researchers at IBS CSLM discovered pair quasiparticles in a classical system of microparticles driven by viscous flow. These long-lived excitations exhibit anti-Newtonian forces that stabilize pairs, similar to the behavior of Dirac quasiparticles in graphene.
Researchers found that female patients with diffuse large B-cell lymphoma treated in the afternoon had reduced mortality rates and cancer recurrence compared to those treated in the morning. The study suggests that timing chemotherapy delivery according to an individual's circadian clock may improve treatment outcomes.
A new study analyzed nearly 20,000 conversations between online users and a chatbot called SimSimi to understand user interactions during the COVID-19 pandemic. The researchers found that daily chats with the chatbot mostly led to positive emotions and reduced negative moods during lockdowns.
Researchers have improved the FDA's equation for predicting drug interactions by addressing fundamental limitations and incorporating new models. The modified equation has shown a significantly increased accuracy of about 80%, which is expected to contribute to increasing the success rate of new drug development.
Scientists have discovered a new form of carbon, LOPC, formed by heating fullerenes with lithium nitride. The new carbon consists of 'broken C60 cages' connected with long-range periodicity, exhibiting unique electrical conductivity properties.
New study reveals marine algae adapt to nutrient-poor ocean conditions, sustaining productivity even in depleted waters. This 'metabolic hack' could impact global ocean productivity and carbon sequestration.
Researchers discovered that synchronized neural oscillations in the right hemisphere of the brain induce empathic behavior in mice, allowing them to perceive and share each other's fear. The study identified the causal relationship between 5-7 Hz oscillations in the cingulo-amygdala circuit and empathic responses.
Researchers have successfully segregated oppositely helical supramolecular polymers in a solution using audible sound, inducing surface vibrations and advection currents. This approach allows for the spatiotemporal control of chiral supramolecular systems, enabling the segregation of multiple aggregates.
Researchers found two Korean native plants' saponins inhibit SARS-CoV-2 entry into cells by blocking membrane fusion. These compounds show promise in treating COVID-19, especially for asymptomatic cases.
The discussion focused on the impact of ocean acidification, compound events, sea-level rise, and climate injustice, with experts highlighting the need for youth involvement in decision-making. The panel agreed on the urgent need for climate action ahead of COP27, emphasizing cooperation between nations to mitigate the crisis.
A new study predicts that global warming will shorten safe ice conditions on frozen lakes by 2-3 weeks over the next 80 years. This will have a significant impact on indigenous communities and regional economies that rely on ice roads.
A study found that aberrant expression of MAO-B causes both peripheral and neuroinflammation in RA patients, leading to joint pain and cognitive impairment. Administering an MAO-B inhibitor called KDS2010 improved both joint inflammation and cognitive function in a RA animal model.
Researchers uncovered crucial interactions between XPA and RPA proteins in NER, essential for repairing UV-damaged DNA. These findings hold promise for improving cancer therapy outcomes by targeting the NER pathway.
Researchers developed a new holographic microscope that can see through the intact skull and image the neural network of a living mouse brain with high resolution. The technology uses a wave correction algorithm to filter out multiple scattered light waves, allowing for sharper images.
Researchers developed a high-resolution holographic endoscope system that can reconstruct microscopic images without attaching equipment to the fiber bundle. The new endoscope has a diameter of 350 μm and achieves spatial resolution of 850 nm, far smaller than the core size of optical fibers.
The Institute for Basic Science (IBS) collaborated with the National Institutes of Health (NIH) and St. Jude’s Children’s Research Hospital to increase virus research capacity and respond to infectious disease outbreaks. IBS and NIAID discussed potential research cooperation opportunities, including joint symposia and resource sharing.