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JAMA Network


Ocular adverse events with semaglutide

A study found no association between semaglutide treatment and diabetic retinopathy, but suggested a potential link to nonarteritic anterior ischemic optic neuropathy. Further research with larger sample sizes is needed to clarify this risk.

SourceJAMA Network·JournalJAMA Ophthalmology·DateAug 14, 2025

Cost-effectiveness of 2023-2024 COVID-19 vaccination in US adults

A modeling study finds that COVID-19 vaccination is more cost-effective for individuals aged 65 and above, with favorable results across different parameter input scenarios. The study's findings support the Advisory Committee on Immunization Practices' decision to recommend vaccination with the 2023-2024 mRNA vaccines.

SourceJAMA Network·JournalJAMA Network Open·DateAug 7, 2025

Mortality among surgeons in the United States

A recent study reveals that surgeons in the United States have a disproportionately high mortality rate compared to other highly educated professionals, including nonsurgeon physicians. The study suggests that factors such as work environment and lifestyle may contribute to this disparity.

SourceJAMA Network·JournalJAMA Surgery·DateJul 30, 2025

Type 2 diabetes and financial outcomes

Patients with type 2 diabetes experience more severe financial difficulties compared to those without the condition. The study emphasizes the importance of considering patient financial health when treating type 2 diabetes, particularly for vulnerable populations.

SourceJAMA Network·JournalJAMA Network Open·DateJul 28, 2025

Safety of JN.1-updated mRNA COVID-19 vaccines

A nationwide cohort study of 1 million adults found no increased risk of 29 adverse events after vaccination with the updated COVID-19 mRNA vaccine containing the SARS-CoV-2 Omicron JN.1 lineage. The study provides reassuring safety data on the new vaccine, which has been widely adopted in response to the Omicron variant

SourceJAMA Network·JournalJAMA Network Open·DateJul 28, 2025

Potential trade-offs of proposed cuts to the NIH

The study uses systems modeling to analyze potential trade-offs of proposed NIH cuts, considering implications for long-term biomedical research and public health. The results suggest that funding policies must consider systemic interactions beyond immediate budgetary impacts.

SourceJAMA Network·JournalJAMA Health Forum·DateJul 25, 2025

Trends in physician exit from fee-for-service Medicare

Physician exit from traditional Medicare has increased over time, with exits remaining high even after the pandemic. The findings suggest that multiple factors contribute to physician departures, including the growing burden of new communication methods and demands for clinical documentation.

SourceJAMA Network·JournalJAMA Health Forum·DateJul 18, 2025

Public perception of physicians who use AI

A study on public perception of physicians who use AI found that while effects are relatively small, they may be highly relevant due to the close link between trust in healthcare practitioners and subjective treatment outcomes. The integration of AI in healthcare has sparked certain reservations among the public.

SourceJAMA Network·JournalJAMA Network Open·DateJul 17, 2025