Researchers have developed a way to detect circulating tumor cells in the bloodstream using biolasers, which can provide valuable information about the DNA organization inside cancer cells. The technique has been successfully tested on pancreatic and lung cancer patients, showing high accuracy rates of up to 99%.
Participants in the National Diabetes Prevention Program saved approximately $5,000 in medical costs over two years due to reduced hospitalizations, outpatient visits, and emergency room visits. Additionally, they showed a lower probability of developing diabetes compared to non-participants.
A study found that standard medical reports are often difficult for patients to understand, leading to increased worry. In contrast, patient-centered pathology reports provide clear and concise information, improving patient comprehension and reducing anxiety.
Early treatment with TNF inhibitors has been shown to prevent complications in kids with Crohn's disease, reducing the risk of perianal fistulas by 82%. The study found that anti-TNF drugs are specifically effective in preventing these debilitating complications, making them a recommended first-line therapy.
A study by Michigan Medicine researchers suggests that sulfur-producing bacteria may be behind lingering Crohn's disease symptoms, even in the absence of inflammation. The study found that these bacteria can lead to increased visceral hypersensitivity and altered intestinal permeability, contributing to persistent symptoms.
A recent study by Michigan Medicine found that reducing the dose of popular blood thinners like Xarelto and Eliquis can lower the risk of future bleeding events. The research team analyzed nearly 1,000 cases of patients who took these medications to prevent recurrent clots after having a blood clot.
A national poll suggests that many parents use threats to manage their preschooler's behavior, including threatening no Santa or gifts. Experts stress the importance of consistency, positive reinforcement, and adapting discipline strategies as children grow.
A new poll by Michigan Medicine found that most people over 50 have at least one close friend, but those with worse physical or mental health are more likely to feel isolated. Close friends can provide emotional support, encourage healthier choices, and help navigate health challenges.
Researchers found no correlation between adenotonsillectomies and undesirable weight gain in children with mild sleep-disordered breathing. The study used data from a clinical trial involving 458 children and showed that adenotonsillectomy improved symptoms, blood pressure, and quality of life but not primary neurodevelopmental outcomes.
A new national study reveals that loneliness and social isolation have returned to pre-pandemic rates for older Americans, affecting 33% of adults aged 50-80. Those with poor physical or mental health face even higher rates, highlighting the need for clinicians to screen patients for these issues and connect them with community resources.
Breast cancer cells can live for years in bone marrow after remission, leading to disease recurrence in approximately 40% of patients. A study found that mesenchymal stem cells support the cancer cells by donating essential proteins, making them more aggressive and drug-resistant.
Researchers have identified UBA1 enzyme as key mediator for immune response to tumors, inhibiting its activity increases T-cell recruitment and lowers tumor resistance. Pairing UBA1 inhibitors with immune checkpoint blockade therapies may make immunotherapy more effective for patients with 'cold' tumors.
A large-scale analysis found that cancer immunotherapies are equally effective for both Black and white patients, with Black patients experiencing a lower risk of severe side effects. The study looked at data from over 26,000 patients treated with immune checkpoint inhibitors through the Veteran Health Administration.
A University of Michigan-led study suggests that recycled pacemakers can be used safely and effectively in patients with life-threatening cardiac conditions. The international clinical trial involved nearly 300 people across seven countries and found no significant differences in pacemaker function up to 90 days after the procedure.
The Centers for Disease Control and Prevention still label cerebral palsy as a childhood disorder, despite more adults living with the condition. A new definition aims to address these gaps in care by recognizing cerebral palsy as a lifelong physical disability.
A national poll of parents finds that many struggle to help their kids manage anger, with 7 in 10 saying they sometimes set a bad example. Effective strategies include teaching children calming tools, recognizing underlying emotions, modeling calm responses, and providing positive reinforcement.
Researchers developed an AI-powered model called FastGlioma that can detect residual tumor tissue with high accuracy in 10 seconds. The technology outperformed conventional methods, reducing the risk of missed tumors by nearly 75%. This innovation could change the field of neurosurgery and minimize reliance on radiographic imaging.
A new poll by Michigan Medicine reveals that having grandchildren and regularly seeing them can have a positive impact on older adults' mental health. Grandparents who care for their grandchildren under 18 or see them frequently are less likely to feel isolated and report better mental health.
A new University of Michigan study analyzed 2022 data from Michigan Medicare participants to assess the impact of virtual care on low-value care. The study found that high-telehealth-use clinics did not see a rise in unnecessary tests and scans, while some saw a faster drop in these procedures.
Researchers at Michigan Medicine found that SLC13A3 transporter impairs tumor immunity by endowing ferroptosis resistance. This discovery suggests a potential target for improving immunotherapy responses in cancer patients.
Researchers developed an algorithm to analyze high-resolution spatial data from Seq-Scope and other technologies, called FICTURE. This enables scientists to see how and where a gene is expressed at microscopic resolution, improving our understanding of gene expression.
A Michigan Medicine study of over 18,500 adults found that obstructive sleep apnea was associated with a higher risk of dementia symptoms or diagnosis at every age level. Women were more likely to be diagnosed with dementia than men, especially as they aged.
Researchers say implementing established strategies is critical to addressing the physician well-being crisis, including reducing workload and facilitating timely mental health treatment. The review also highlights the need for policies supporting diverse perspectives to improve well-being among underrepresented groups.
A new study found that 3% of people with traditional Medicare switch to Medicare Advantage each year, but many switch back after a short period. The researchers discovered that people who switched from MA to traditional Medicare were more likely to choose higher-rated plans or those with broader networks.
A University of Michigan-led study found that treatment with either modafinil or cognitive behavioral therapy alone was associated with significant reductions in fatigue over 12 weeks. A combination of both treatments worked as well as each individual treatment but did not result in better fatigue scores.
Researchers have found that women are more likely to die from postoperative complications after high-risk cardiovascular surgery, with a failure to rescue rate of 10.7% compared to 8.6% for men. The quality of hospital where the procedure was performed did not affect this disparity.
A recent poll found that 74% of people over 50 would not trust health information generated by artificial intelligence. Only 32% of older adults reported it's very easy to find something accurate online. Health systems, academic institutions, and government agencies can use the results to improve health information accessibility.
Researchers analyzed nationally representative data and found a 76% increase in emergency encounters related to hypertensive disorders of pregnancy. The condition, which causes serious maternal and neonatal complications, accounts for 6.3% of all pregnancy-related deaths in the US.
A new study by University of Michigan researchers found that the Medicare prior authorization policy aimed at reducing hospital outpatient department based surgical volume had no significant impact. The policy, which requires doctors to get prior authorization from Medicare officials before scheduling certain outpatient procedures, did...
A recent study found that tau protein buildup disrupts the salience network, a crucial communication network in the brain, leading to behavioral changes. The study used advanced medical imaging to analyze the brains of 128 people with early-stage dementia and showed a strong association between tau disruption and behavioral symptoms.
Researchers at Michigan Medicine have discovered a new subtype of aggressive prostate cancer and identified a potential degrader to target it. The study found that a genetic alteration in the CDK12 gene drives cancer development, and a degrader targeting this gene shows promise in destroying cancer cells.
A new study found significant disparities in at-home test use among older adults, with those having a college degree or higher and higher incomes being more likely to use them. However, Black older adults were less likely to use these tests compared to other racial/ethnic groups.
The number of female residents matriculating to high-paying medical specialties has increased over the past 14 years, driven by a notable rise in women entering high-compensation surgical fields. Despite ongoing inequities, the proportion of female matriculants to these specialties has risen from 32.7% in 2008 to 40.8% in 2022.
Researchers at Michigan Medicine develop a composite hydrogel capable of steady, sustained drug release using ultrasound as a trigger. The fibrin hydrogel matrix vaporizes an emulsion upon exposure to ultrasound, releasing the encapsulated drug in a zero-order release process, providing consistent levels over time.
The #HOPE4LIVER trial demonstrated the safety and efficacy of histotripsy as a treatment for primary and metastatic liver tumors, achieving a 95% technical success rate. The procedure's non-invasive nature and ability to spare critical vessels and bile ducts offer promising alternatives to traditional treatments.
Researchers found that liraglutide alters iron metabolism, decreasing liver iron storage and circulation. The study suggests a potential new therapeutic option for patients with hereditary hemochromatosis.
A new poll from Michigan Medicine shows that nearly half of people age 50 and older plan to get the updated COVID-19 vaccine. However, some older adults with high risk of severe illness appear unlikely to seek the vaccine, highlighting the need for increased encouragement from clinicians and other sources.
A new study found that up to 10 million people in the US could qualify for Medicare-covered semaglutide injections, depending on their level of cardiovascular risk. Those with higher risk scores would be eligible for full or partial coverage, potentially expanding access to this life-saving medication.
Researchers developed a multi-variable model called Hear-MHE that analyzes speech patterns to identify symptoms of minimal hepatic encephalopathy. The test shows promise in predicting overt hepatic encephalopathy and could lead to earlier diagnosis and improved treatment.
Researchers found that adopting an electronic patient management system for direct oral anticoagulants reduced off-label dosing by 8%, while also decreasing the rate of blood clots and strokes. The online dashboard, used at over 120 hospitals, highlights treatment optimization and improves patient safety.
A new poll shows that 21% of people aged 50 and older used cannabis in the past year, with 12% using it at least monthly. The study highlights potential risks of cannabis use, including risky driving and addiction, as well as the importance of discussing its use with healthcare providers.
A new study by Michigan Medicine found that the Inflation Reduction Act's limit on Medicare Part D spending leads to significant savings for cancer patients prescribed oral chemotherapy. The average annual cost for these medications decreased from $11,284 in 2023 to $3,927 in 2024, resulting in median cost savings of $7,260.
A new study published in Nature Communications reveals how propofol sedation alters the connections between brain cells in the thalamus and cortex, shedding light on the neural mechanisms underlying consciousness. The researchers found that disruptions to the matrix cells' activity play a crucial role in the transition to unconsciousness.
A new study has identified NSD2 as a fundamental factor in early stages of prostate cancer development, found to alter androgen receptor function leading to rapid cell division and growth. The study may suggest a new way to therapeutically target prostate cancer by targeting the epigenetic component NSD2.
The new guideline updates treatment recommendations for Helicobacter pylori infection, shifting away from proton pump inhibitor-clarithromycin triple therapy. Bismuth quadruple therapy and other alternatives are now recommended for treatment-naïve patients.
A study found that ketamine clinics have inconsistent policies on pregnancy-related safeguards, including inadequate warning systems and contraception prescription. This is concerning given the potential harm of ketamine to developing fetuses.
A study by the Michigan Child Health Equity Collaborative found significant inaccuracies in racial and ethnic designations in children's medical records, ranging from 22% to 59% for race and 5% to 35% for ethnicity. These errors may undermine efforts to identify health inequities and disparities.
Researchers found that people with chronic diabetes complications are up to three times more likely to have a mental health condition, while those with mental health disorders are up to two and a half times more likely to experience sustained diabetes complications. The study highlights the importance of screening for both risk factors.
A new national study reveals significant regional variations in the likelihood of being diagnosed with Alzheimer's disease or another form of dementia. Despite controlling for demographic and population-level risk factors, the study found that differences in diagnostic intensity persist across regions.
A new study shows that healthcare costs, including medical care, prescription drugs, and long-term care, are among the top health-related concerns of older adults heading into the US election. Financial scams and fraud also made the top six concerns, with significant differences among age, gender, and political ideology.