A NUS study found that corals in Singapore's waters typically don't extend beyond eight metres, reducing the impact of rising sea levels. The research highlights the resilience of coral reefs in Singapore and informs conservation efforts.
A study by NUS researchers found a close association between liposarcoma and the bromodomain and extraterminal (BET) protein family. The development of LPS is highly dependent on the presence of BET proteins, making them a promising cancer target for treatment.
A NUS pilot study demonstrates the potential of CURATE.AI to create individualized profiles for customized training, leading to improved cognitive performance. The AI platform tailors training intensity and duration based on a person's unique response data.
Researchers identify Aurora-A kinase as the master switch that triggers symmetry breaking and establishes cell polarity in nematode worm zygotes. The protein regulates actomyosin contractions, creating a two-stage process to establish front-rear asymmetry and lock polarity regulators in place.
The team developed a transparent, waterproof, and conductive material that can repair itself in both air and water environments. This innovation has the potential to reduce electronic waste by enabling devices to perform self-repair functions.
The study reveals that using a metallic substrate with higher chemical reactivity can significantly increase the phase transition yield of 2D-TMD materials. This method enables the easy achievement of structural phase transitions and opens possibilities for new device applications such as low contact resistance electrodes.
A recent study by NUS researchers found that microplastics can harbor toxic bacteria capable of causing coral bleaching and triggering wound infections in humans. The study identified over 400 types of bacteria on the plastics, including species that can degrade pollutants and others that cause harm to marine organisms.
A NUS study reveals that crossbreeding between milky storks and their cousins is threatening the species' conservation. The research found that more than half of the stork population in Singapore is genetically influenced by Painted Storks, posing a major threat to the species' survival.
Researchers from NUS discovered that certain nanoparticles can widen the gap between blood vessel cells, making it easier for cancer cells to spread. This phenomenon, named NanoEL, accelerates tumor growth and causes circulating cancer cells to escape from blood circulation.
The National University of Singapore engineers have developed a novel bottom-up synthesis strategy to consistently construct TMD QDs of specific size, offering a cheaper and more scalable method. The synthesized MoS2 QDs demonstrate potential biomedical applications, including photodynamic therapy for cancer treatment.
Researchers employed machine learning to analyze fMRI data and infer cellular properties of different brain regions without surgery. The approach could lead to personalized treatment plans for neurological disorders.
A recent NUS study reveals that older adults make similar financial decisions for themselves and others, while younger adults take more risks when making decisions for others. This suggests that older adults care more about strangers' welfare in financial decision-making.
A recent NUS study reveals that lower-income households in Singapore use more water to cool down during hot weather, whereas higher-income households rely heavily on air-conditioners, increasing their electricity demand.
Researchers have developed a novel ferrimagnetic spintronic memory device, outperforming traditional ferromagnet-based memories in terms of stability and efficiency. The new technology has the potential to accelerate the growth of the spintronic industry.
Researchers at NUS developed a low-cost 'battery-less' wake-up timer that significantly reduces power consumption of silicon chips for IoT sensor nodes. The innovation enables long-lasting IoT applications and paves the way for aggressive miniaturization of IoT devices.
A lack of production standards in the graphene market has led to inferior products being sold as high-grade. NUS researchers developed a reliable method for testing graphene quality, finding that most samples contained less than 10% real graphene flakes.
Two NUS studies examine the relationship between a crab spider and its pitcher plant host, revealing that when resources are scarce, this partnership is beneficial. The research suggests that under stressful conditions, mutualism increases in frequency and intensity, supporting the idea that a 'friend in need' can be beneficial for all...
A NUS study found that mangroves can capture more carbon than tropical rainforests, making them a key solution to reduce fossil fuel emissions. Coastal ecosystems like mangroves can store organic carbon in water-saturated soil, effectively mitigating climate change.
A NUS study found that overexpression of ADAR1 and irregular RNA editing of NEIL1 are key factors in MM progression and drug resistance. The study offers novel insights for new therapeutic strategies.
Researchers from NUS developed novel lead halide perovskite nanocrystals for high-sensitivity X-ray detection, reducing diagnostic radiation dose by 400 times. These nanocrystals also enable lower-cost and faster imaging technology with improved resolution.
A new songbird species, the Rote Leaf-Warbler, has been discovered on an Indonesian island through genomic analysis. The discovery highlights the island's conservation value due to its unique characteristics and threatened habitats.
Researchers at NUS Cancer Science Institute identified a SCC-specific protein complex triggered by TP63 and SOX2, promoting SCC growth through gene cascades. This discovery offers avenues to target SCCs and pave the way for innovative therapies.
Scientists have found that low TIP60 expression leads to uncontrolled jumping gene expression, triggering tissue inflammation that supports tumor growth. The discovery opens new avenues for cancer treatment using anti-HIV drugs.
The enVision platform detects diseases in 30 minutes to an hour, with costs under S$1 per test. The technology uses enzyme-assisted nanocomplexes to identify nucleic acids and has demonstrated superior sensitivity and specificity compared to clinical gold standard.
A clinical study using the CURATE.AI platform successfully treated a patient with metastatic castration-resistant prostate cancer, completely halting disease progression. The AI platform continuously optimised novel drug combination dosages to achieve a durable response, allowing the patient to resume an active lifestyle.
Researchers found that RUNX proteins bind to DNA damage sites and co-regulate the recruitment of DNA repair protein FANCD2. This discovery could lead to the development of synthetic-lethal approaches to attack RUNX-deficient cancers, including solid tumours of the breast and leukemia.
Researchers at NUS have developed an AI technology platform that can quickly determine the most effective drug combination for a patient. The Quadratic Phenotypic Optimisation Platform (QPOP) uses small experimental data sets to identify effective drug combinations and personalized treatment options.
A research team has developed a novel peptide drug called FFW that shows promise in reducing tumour growth and slowing down the spread of cancer cells. The drug targets SALL4 protein interactions, previously considered undruggable, and has shown effective results in lab experiments.
Scientists at NUS have discovered a practical way to observe and examine the quantum effects of electrons in topological insulators and heavy metals. This breakthrough enables the development of advanced quantum computing components and devices, potentially answering some of the world's toughest questions in finance and physics.
Researchers at NUS have successfully reprogrammed mature cells into pluripotent stem cells by confining them in a defined geometric space for an extended period. By the 10th day, the cells expressed genes associated with embryonic stem cells and iPSCs, indicating complete transition into re-deployable stem cells.
Marine organisms easily ingest nanoplastics, which accumulate in their bodies over time, threatening food safety. Nanoplastics can transfer up the food chain, affecting human health, as shown in a recent study using acorn barnacles.
Researchers developed a novel gel-like material that effectively dehumidifies ambient air while harnessing the moisture in the air for various applications. The hydrogel can absorb water from surrounding air more than 2.5 times its weight and performs at least eight times better than commercial drying agents.
Researchers have developed a novel microchip called BATLESS, which can continue to operate even when the battery runs out of energy. The chip uses a small on-chip solar cell to harness energy from the environment, allowing it to switch between minimum-energy and minimum-power modes.
A NUS-led study reveals that a beltway in Sao Paulo diverted heavy-duty diesel vehicles, reducing public health damage from diesel emissions. The intervention led to a sustained drop in nitrogen oxides levels and improved air quality.
Researchers from NUS have made a breakthrough in understanding the magneto-resistance effect and its relation to spin texture of topological surface states. The team's findings could help in addressing the issue of spin current source selection in spintronic devices.
A team of scientists led by Professor Lim Chwee Teck at NUS has won a US$1.2 million Human Frontiers Science Program Research Grant for novel multidisciplinary work on cell collective migration on curved surfaces, aiming to advance tissue growth and repair in regenerative medicine.
A study by researchers at the National University of Singapore found that almost half of breast cancer patients experience cognitive decline during treatment, with symptoms persisting up to a year after. The study highlights the importance of early screening and management to improve quality of life for survivors.
A team of NUS engineers discovered a novel method to convert cellulose to biobutanol directly using the Thermoanaerobacterium thermosaccharolyticum TG57 strain, isolates from mushroom waste. This breakthrough could improve sustainability and reduce costs in biofuel production without competing with food crops.
Researchers at NUS have developed a tiny microfluidic chip that can detect minute amounts of biomolecules without complex equipment. The chip uses standard lab microscopes to spot nano-biomolecules, making it attractive for point-of-care diagnostics.
Scientists from NUS and international research team create a novel method for deep brain stimulation, utilizing upconversion nanoparticles to deliver visible light deep into the brain. The innovation enables researchers to uncover valuable insights about brain functions with less invasive methods.
A NUS study has identified complex networks driving international wildlife trade, with large portions of markets remaining unknown. The findings suggest a nuanced approach to regulation is needed to address unsustainable harvesting and species extinction.
In a groundbreaking study, male white-spotted bush frogs have been found to dedicatedly guard their fertilized eggs from other male frogs and predators. This unique parental care behavior significantly enhances offspring survival rates, with up to 70% of 'fatherless' egg clutches perishing.
A team of scientists from the National University of Singapore has developed a way to wirelessly deliver light into deep regions of the body to activate light-sensitive drugs for photodynamic therapy (PDT). The technology enables PDT to be used on inner organs with fine control, potentially treating a wider range of cancers.
A team of scientists developed a novel platform to study lumen formation in epithelial tubes, which can lead to diseases like atherosclerosis and kidney failure. The 3D microtube setup allows cells to form tubes under different physical constraints, revealing the importance of mechanical forces in tissue development.
Endocytic waves initiated by clathrin emerge in some cell populations and are temporally related to downstream waves of F-BAR and other actin regulating proteins. This study reveals the link between endocytosis and generation of cortical actin waves, providing insight into how cells maintain plasma membrane composition.
Researchers developed a QKD system that achieves high secret key rates using time-bin encoding, resolving major challenges for practical applications. This breakthrough enables ultra-high rate quantum secure communication, paving the way for image and video encryption and large encrypted databases.
Researchers at NUS Cancer Science Institute discovered a molecular pathway in which TIP60 inhibits cancer cell growth by targeting telomerase. This finding offers a new approach to treating various types of cancer triggered by high telomerase levels.
Researchers from the National University of Singapore have successfully demonstrated room temperature magnetisation switching driven by giant SOTs in topological insulator/conventional ferromagnet heterostructures with an extremely low current density, overcoming scalability and power consumption issues.
A team of NUS scientists has developed a prototype device that mimics natural photosynthesis to produce ethylene gas. The device uses only sunlight, water, and carbon dioxide, reducing the carbon footprint of ethylene production.
The NUS microfibre sensor measures vital signs, heart rate, and blood pressure in real-time, offering convenience and comfort for patients. It can also detect plaque buildup in blood vessels, potentially preventing organ failure or heart attacks.