Researchers have combined 14 studies on piglet gut bacteria to uncover common patterns in microbiome development over time. The analysis revealed predictable trajectories and important details at a fine time scale, with an accuracy of 70% in predicting animal age based on microbiomes.
Researchers at Purdue University developed a new tool to visualize neural network decisions, making it easier to identify errors in image recognition. The tool uses graph-topological data analysis to provide a bird's-eye view of all images in a database, revealing areas where the network struggles to distinguish between classifications.
Researchers at Purdue University have developed a novel cancer immunotherapy compound that targets the enzyme TC-PTP, found in both cancer cells and T cells. Deleting this enzyme promotes antigen presentation, alerting the immune system to tumor cells, while stimulating T-cell activation enhances their ability to fight and destroy tumors.
Researchers at Purdue University have developed noninvasive wearable sensors that can measure uric acid levels in human sweat, offering faster and more accurate diagnosis, therapy, and prognosis for conditions like anxiety and hypertension. The sensors, called EPICS, have higher sensitivity and better wearability than traditional sensors.
Researchers at Purdue University propose using vanadium oxides to create neuromorphic computing hardware that mimics brain behavior. This breakthrough aims to improve energy efficiency and computational performance in AI systems.
Research at Purdue University shows that microplastics affect zooplankton's ability to feed on algae, leading to increased algal densities and potential toxin release. This study highlights the ecological impacts of plastics on aquatic food webs and emphasizes the need for further research.
Researchers at Purdue University detect unprecedented levels of alloy aerosols in the atmosphere, likely from spacecraft and satellites. The team found that nearly 10% of large sulfuric acid particles contained aluminum and other spacecraft metals.
Purdue University scientists examine the bio-impact of toxic chemical cocktails in the environment, finding reduced growth in tadpoles exposed to PFAS mixtures. The study highlights the need for research on mixture toxicity in aquatic organisms, as each chemical interacts with others in complex ways.
The company will use the funding to develop a novel method to produce high-accuracy optical encoders, which are crucial for modern automation and robotics systems. The goal is to enable the manufacturing of complex next-generation products with precision positioning and motion control.
The research aims to understand the molecular response of plants to environmental stress by investigating the connection between two independent biochemical signaling pathways, ethylene biosynthesis and autophagy. The findings could lead to the development of high-yield, pathogen-resistant, stress-tolerant plants.
Philip Low, a Purdue University researcher, is working on validating a previously successful malaria treatment by reducing the number of days required for therapy. His goal is to prevent drug-resistant strains from proliferating and save lives in developing countries.
A team of chemists at Purdue University has created a sustainable adhesive system that uses epoxidized soy oil, malic acid, and tannic acid. The new adhesive is inexpensive, effective, scalable, practical to produce and completely sustainable.
A new spatial database created by Purdue University scientists combines data collected on-site and via satellite to provide detailed maps of planted forests in East Asia. The database lists the most common tree species growing there, such as pine and eucalyptus, and covers 87.0% of planted forest in China.
A team of Purdue researchers developed patent-pending adhesive formulations from sustainable bio-based components that grow stronger when exposed to water. The adhesives have potential applications in coral reef restoration, construction, biomedical, dental, food, and cosmetic industries.
Researchers developed a targeted microRNA therapy that slowed cancer tumor growth in a 21-day study. The therapy, which combines a delivery system with modified microRNA-34a, suppressed the activity of genes driving cancer and resistance to other therapies.
The patented cooling pads designed by Purdue researchers improve feed intake and milk output in sows and increase piglet weaning weight. The technology also maintains boar semen quality and reduces heat stress abnormalities.
Researchers at Purdue University have developed a 'mini-brain' that tracks the effects of concussive force on brain cells, revealing a link between head trauma and Alzheimer's disease. The study found that even hours after a hit, acrolein production leads to misfolded amyloid beta protein aggregation.
A Purdue University research team has revealed complex new details about the function of a key protein shared by mammals, including humans. The study shows that DNA methylation plays an important role in how young, unformed mammalian cells divide and develop into more specialized cells.
Researchers sequenced the genome of Prymnesium parvum, a microscopic algae species causing toxic blooms in US waters. The study found significant genetic variation among strains, suggesting multiple populations and potential hybridization cases. This discovery could improve prediction models for algal blooms and ecosystem disruption.
Researchers genetically engineered plants to study lignin biosynthesis, but found a compound called pinoresinol restores growth by affecting root hair production. This suggests a broader function for pinoresinol in plant development beyond just lignin synthesis.
Anu, a startup company founded by Purdue University alumni, has received a $200,000 Indiana Manufacturing Readiness Grants award to mass manufacture its aeroponic seed pod consumables. The funding will enable the company to scale its sustainable platform for consumers, supplying growers with recurring seed pod subscriptions.
Researchers at Purdue University and NIH have identified 14 understudied T-reg proteins with molecular roles in disease onset, offering new avenues for understanding autoimmune diseases and cancer. Studying these proteins could lead to the development of cell-based therapies to modify their functions.
Researchers at Purdue University have developed an innovative thermal imaging method called HADAR, which enables artificial intelligence to perceive physical attributes and recover textures in pitch-dark environments. The technology has the potential to revolutionize fields such as autonomous vehicles and robotics.
A Purdue University experiment is investigating how reduced gravity affects boiling and condensation, crucial for long-term space habitats. The research aims to provide data needed to answer decades-old questions about these phenomena in weightlessness.
Aerovy Mobility, a cloud solutions provider for electric aviation, received $140,000 from the Startup Foundry investment. The company plans to use the funds to launch its live operations tool, VEMS, at vertiports and airports worldwide. Uniform Sierra Aerospace, a drone manufacturer for public safety departments, also benefited from th...
Researchers at Purdue University have received funding from the Trask Innovation Fund to further develop their work in freeze-drying pharmaceuticals, certifying grass-fed beef, and thermal imaging for autonomous navigation. The fund will support the creation of prototypes and testing for these innovative technologies.
Amplified Sciences has received a $400,000 NCI grant to develop and validate an assay testing for the detection of pancreatic cancer in patients diagnosed with pancreatic cystic lesions. The company aims to improve the accuracy of diagnoses, reducing unnecessary surgical interventions.
Biotechnology holds promise for saving endangered tree species through a combination of traditional breeding approaches and innovative genetic engineering. The study emphasizes the need for public acceptance and regulators' support to harness biotech's potential.
Researchers using genetic databases study the interaction between biological forces and social environments to better understand complex behaviors. By analyzing massive banks of genetic data, scientists can clarify the nuances of human behavior and improve social science research.
AnalySwift will develop DATC, a design tool for engineers to analyze lightweight structures made from advanced tailorable composites. The tool aims to improve NASA's capabilities in designing and analyzing aerospace structures, reducing the need for costly physical experiments.
Researchers at Purdue University have demonstrated tunable moiré magnetism in twisted double bilayers of chromium triiodide, a material that can be used for spintronics. This discovery suggests a new class of material platform for spintronics and magnetoelectronics.
The Great Sitkin Volcano in Alaska has two magma chambers that drive its long-lived and explosive eruptions. Scientists have discovered a six-stage eruption cycle, with the interaction between the chambers contributing to lava effusion. This study helps predict volcanic eruptions and assess hazards.
Researchers at Purdue University have developed a new steel alloy with extraordinary strength and plasticity, achieving a yield strength of about 700 megapascals. The treatment produced ultra-fine metal grains that exhibit super-plasticity, allowing the material to stretch and bend without rupturing.
Researchers have discovered that a previously unknown strategy is used by the foodborne bacterium Listeria monocytogenes to invade and infect humans and animals. A housekeeping enzyme called LAP plays a crucial role in this process, and its attachment to the bacterial surface is essential for pathogenesis.
The Purdue-led USDA project, IMPACT2, aims to double the impact of climate-smart agriculture in the Midwest by addressing near-term and long-term issues faced by farmers. The project will offer scenario-based activities, training, and information to diverse stakeholders, with a goal of reaching 2,000 participants via an online portal.
Researchers at Purdue University have developed a technique to identify Parkinson's disease-linked proteins and their downstream pathways in urine samples using EVtrap technology. This noninvasive method may lead to widespread early diagnosis and intervention for neurodegenerative diseases, including cancer.
Researchers at Purdue University have discovered that superconductive images are actually 3D and disorder-driven fractals. The team used fractal mathematics to characterize the shapes of electrons in a cuprate high-temperature superconductor, revealing patterns that challenge current understanding of quantum materials.
Astronomers have discovered a supermassive black hole consuming a giant star, producing a long-lived transient object that is orders of magnitude brighter and more energetic than any recorded before. The object, named Scary Barbie, has lasted over two years and may be visible for years to come.
TRIO Pharmaceuticals is developing a proprietary platform of dual-action tumor immunity-enhancing drugs aimed at treating cancers with high unmet medical needs. The company's innovative approach selectively eliminates immunosuppressive cells, enhancing antitumor activity.
Purdue University has received two grants of $1 million each from the US Department of Agriculture's National Institute of Food and Agriculture to develop more resilient food systems. The grants will support research, education, and extension efforts aimed at enhancing sustainable agricultural systems in Eastern U.S. forests and Midwes...
The research demonstrates that low concentration ether-based electrolyte can successfully endure the long-term high voltage operation of practical LMB. The findings show that regulating solvation structure and adjusting surficial electric double layer can prevent degradation and improve performance.
A research review found that COVID-19 lacks canine data, fueling concerns about the risk of pet animals serving as virus reservoirs. The lack of testing has made it difficult to understand the susceptibility of dogs to the new variants.
A sensor embedded in concrete allows for more precise data on pavement strength, reducing the need for repairs and improving road sustainability. This technology has been implemented in several states, including Indiana and Texas, to reduce traffic delays and save taxpayer dollars.
A team of Purdue University scientists has identified a protein that plays a key role in helping petunias emit volatiles, challenging the idea that simple diffusion is responsible. The study focuses on how volatiles cross the cell wall, a barrier that separates the cellular interior from the plant's outermost protective layer.
Researchers at Purdue University have created a new method for incorporating phase change materials (PCMs) into building envelope elements, which reduces energy consumption by moderating temperature fluctuations. The process increases the thermal inertia and compressive strength of construction materials while making them more resilien...
Physicists have discovered a new family of quantum matter, the 'bubble phase of composite fermions,' which exhibits a crystalline pattern and allows electricity to flow along its edge. This discovery confirms the existence of a new type of highly correlated topological phase.
Researchers at Purdue University have developed heterostructures that support the prediction of counterpropagating charged edge modes at the v=2/3 fractional quantum Hall state. The team's experiment measured an electrical conductance equal to half the fundamental value of e^2/h, consistent with theoretical predictions.
Tactile Engineering's Cadence tablet allows users to access technical diagrams and read equations using a refreshable display of electronic cells. The investment will enable the company to manufacture Cadence in larger quantities, supporting its mission to strengthen Braille literacy and equal-opportunity STEM education.
HemaChrome, a digital health startup, has won phase 1 of the National Institutes of Health's RADx Tech for Maternal Health Challenge. The company uses smartphone technology to noninvasively measure blood hemoglobin levels, making them accessible and affordable for nearly everyone.
A $10 million USDA grant will help increase the production of seafood in the Midwest, which is healthier and more sustainably produced than land-based foods. The project aims to promote aquaponics and reduce reliance on imported seafood, which can be affected by volatile markets and environmental issues.