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Rice University


Synthetic cells make long-distance calls

Engineered E. coli bacteria using transcriptional circuits from Rice lab researchers can synchronize gene expression across large distances, enabling collective action in community settings. The discovery could lead to treatment of gut microbiome conditions and interaction with bioelectronics.

SourceRice University·JournalNature Chemical Biology·DateOct 15, 2019

Overlap allows nanoparticles to enhance light-based detection

Researchers at Rice University have developed a method to amplify the light emitted by molecules using plasmonic nanoparticles. By optimizing the spectral frequency overlap between the molecule and nanoparticle, they can enhance signal detection up to 10 times. This technique has potential applications in analyzing catalysts and improv...

SourceRice University·JournalThe Journal of Chemical Physics·DateOct 14, 2019

Quantum material goes where none have gone before

Physicists at Rice University have created a new alloy that exhibits unusual electronic properties when traversing the final frontier of quantum criticality. The cerium palladium aluminum alloy behaves like a spin liquid, a metallic system with exotic properties that can be found in other strongly correlated materials.

SourceRice University·JournalNature Physics·DateSep 30, 2019

Extra amino acid could work wonders

Rice University chemist Han Xiao is developing a custom-designed 21st amino acid to make life-saving substances and produce novel proteins for therapies. The goal is to create 'unnatural organisms' that can produce multiple designer amino acids, leading to breakthroughs in immunotherapy and cancer treatment.

Chemists clarify a chiral conundrum?

Rice chemists disentangled the mysterious interactions between bovine serum albumin and gold nanorods, revealing multilevel chirality and a possible way to sense single proteins' handedness. This discovery could lead to the development of drug-sensing tools with improved accuracy.

SourceRice University·JournalScience·DateSep 26, 2019

Probes shed new light on Alzheimer's cause

Researchers have developed a way to track the formation of soluble amyloid beta peptide aggregates implicated in the onset of Alzheimer's disease. The ruthenium-based fluorescent complexes bind to these aggregates, allowing researchers to monitor their progress and movements over time.

Nano bulb lights novel path

Researchers at Rice University have created a tunable, nanoscale incandescent light source by combining near-nanoscale materials that absorb heat and emit light. The system's unique configuration allows for the emission of light in specific states and wavelengths, including infrared.

SourceRice University·JournalAdvanced Materials·DateSep 19, 2019

Deep dive for dark matter may aid all of data science

Rice astroparticle physicist Christopher Tunnell leads a $1 million NSF-funded project to enhance data science techniques in physical sciences, aiming to push discovery past the tipping point. The study focuses on dark matter searches and employs probabilistic graphical models to improve measurements of particle interactions.

Study points to new drug target in fight against cancer

A study has identified a potential new drug target in the fight against cancer by targeting a protein that blocks the primary gateways in mitochondria. The research found that mitoNEET can close voltage-dependent anion channels (VDACs), which normally allow metabolites and signaling molecules to pass through.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateSep 18, 2019

One-atom switch supercharges fluorescent dyes

Researchers at Rice University have discovered a simple method to turn fluorescent tags on and off with visible light by switching one atom. This technique will enable high-resolution imaging and dynamic tracking of biological processes in living cells, tissues, and animals.

SourceRice University·JournalJournal of the American Chemical Society·DateSep 9, 2019

Hidden signals may hold key to mechanism of memory

Caleb Kemere and his team will investigate how sleep reorganizes information in the brain, aiming to identify critical time windows and neuronal activities involved in storing and stabilizing memories. The researchers hope to gain a better understanding of how sleep impacts lives, including its impact on memory consolidation.

Quest for new cancer treatment crosses milestone

A cancer therapy invented at Rice University has shown promising results in clinical trials, destroying tumors without debilitating side effects. Thirteen of the first 15 prostate cancer patients treated with AuroLase Therapy showed no detectable signs of cancer a year after treatment.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateAug 26, 2019

Scientists advance search for memory's molecular roots

Scientists have detailed the structure of calcium-calmodulin-dependent kinase II (CaMKII), a key protein involved in encoding memories. The study reveals how CaMKII binds to actin filaments, forming rigid bundles that support dendritic spines and enable cognitive functions.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateAug 26, 2019

Nano-thermometer takes temperature inside cells

Researchers developed a fluorescent nano-thermometer that can detect temperature changes inside single cells by monitoring the light-emitting properties of molecular motors. The technique could be useful for identifying cancer cells and measuring the effects of tumor ablation therapy.

SourceRice University·JournalThe Journal of Physical Chemistry B·DateAug 22, 2019

Damaged hearts rewired with nanotube fibers

Researchers at Texas Heart Institute and Rice University have developed biocompatible nanotube fibers that can bridge damaged heart tissues and deliver electrical signals to restore heart function. The fibers were shown to be effective in restoring conduction in preclinical models, even without the presence of a pacemaker.

Sharp meets flat in tunable 2D material

Rice University scientists develop a unique two-dimensional material with sharp zigzag boundaries, showcasing promise for optoelectronics and advanced computing. The material's band gap can be tuned in a controllable way, opening up new avenues for research and potential applications.

SourceRice University·JournalNano Letters·DateAug 12, 2019

Bacteria made to mimic cells, form communities

Researchers at Rice University have created a genetic circuit that allows bacteria to differentiate like stem cells, forming genetically distinct communities with complex behaviors. The discovery, called asymmetric plasmid partitioning, enables the creation of diverse populations of microbes that can exhibit non-native behaviors.

SourceRice University·JournalNature Chemical Biology·DateAug 12, 2019

Rice, UTHealth search for clues to fight antibiotic resistance

Researchers at Rice University and UTHealth have discovered that vancomycin-resistant Enterococci (VRE) can develop resistance to daptomycin in more than one way. The study's findings provide new insights into the mechanisms of antibiotic resistance, which could lead to the development of new treatment strategies or 'co-drugs' targetin...

SourceRice University·JournalAntimicrobial Agents and Chemotherapy·DateAug 12, 2019

You're not so tough, h-BN

Researchers at Rice University have created a method to modify hexagonal-boron nitride (h-BN) by attaching carbon chains, making it easier to bond with polymers and other materials. This modification also makes the material more dispersible in organic solvents.

SourceRice University·JournalThe Journal of Physical Chemistry C·DateAug 12, 2019

Rice chemists show it's hip to be square

Rice University chemists have developed a fast and inexpensive synthetic route to azetidines, a class of molecules that can be used as building blocks in drug design. The new method allows for the creation of NH-azetidines, which contain unprotected nitrogen atoms, making them more accessible for further reactions.

SourceRice University·JournalAngewandte Chemie·DateAug 9, 2019

Paper trail leads to heart valve discoveries

Researchers create paper-based structures that mimic aortic valves, allowing them to study how calcifying diseases slow or stop hearts from functioning. The device helps understand the chemical transactions in heart disease and may eventually lead to non-invasive medication.

SourceRice University·JournalActa Biomaterialia·DateAug 5, 2019

Rice lab produces simple fluorescent surfactants

Researchers at Rice University have developed a set of eight fluorescent surfactants that can capture images of single nanotubes or cells using fluorescent microscopy. These compounds show promise for use in medicine, manufacturing, water purification and biomedical applications.

SourceRice University·JournalPure and Applied Chemistry·DateAug 5, 2019

Oddball edge wins nanotube faceoff

The Rice team found that the Janus configuration, with a half-circle of zigzags opposite six armchairs, allows for tight contact with solid catalysts and preserves continuous nanotube growth. This discovery advances understanding of growth mechanisms and has implications for designing efficient catalysts.

SourceRice University·JournalACS Nano·DateJul 29, 2019

Rice device channels heat into light

Researchers at Rice University have created a device that channels waste heat into light, enabling more efficient solar energy systems. The technology, which utilizes carbon nanotube films, aims to simplify the process of turning heat into electricity with high efficiency.

SourceRice University·JournalACS Photonics·DateJul 12, 2019

'Hot spots' increase efficiency of solar desalination

Researchers at Rice University developed a method to increase the efficiency of solar-powered desalination systems by concentrating sunlight into 'hot spots' using inexpensive plastic lenses. This approach boosts output by more than 50% and increases purified water production, addressing global water scarcity issues.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateJun 18, 2019

How bosses react influences whether workers speak up

A new study from Rice University psychologist Danielle King found that how leaders respond to employee suggestions can impact whether or not the employee opens up in the future. Employees who receive sensitive explanations for rejected ideas are more likely to offer suggestions again in the future.

SourceRice University·JournalJournal of Occupational and Organizational Psychology·DateJun 11, 2019