A new meta-analysis of 215 COVID-19 studies reveals a wide range of ways the virus affects mental health and brain function. Common symptoms include fatigue, loss of smell, depression, anxiety, and headaches, even in mild cases, suggesting that mental health impacts may be more prevalent than expected.
Researchers found that prior COVID-19 infections reduced the risk of reinfection by 85% for care home residents and 60% for staff within a four-month period. The study, published in Lancet Healthy Longevity, used antibody testing to determine previous infection status.
A new UCL study finds that Arctic sea ice in coastal regions is thinning at a rate of 70% to 100% faster than previously thought. The study uses a novel snow model and satellite radar observations to estimate the overall rate of decline of sea ice thickness in the Arctic, with implications for human activity in the region.
Scientists have measured the mass of human chromosomes using X-rays for the first time, finding them to be significantly heavier than expected. The study's results suggest there may be unexplained excess mass in chromosomes, which could have important implications for understanding human health and diagnosing cancer.
Researchers at University College London have pioneered a single-dose radiotherapy approach for breast cancer treatment that is as effective as traditional radiotherapy and avoids potential damage to nearby organs. The treatment, TARGIT-IORT, has been shown to reduce the risk of fatal cardiovascular disease and other cancers in patients.
Researchers discovered a sub-set of CAR T-cells called 'stem cell memory T-cells' that play a key role in destroying cancer and maintaining immune surveillance. These cells are critical to the long-term success of CAR T-cell therapy, which could improve treatment outcomes for patients with high-risk relapse.
Researchers identify 'antisense long non-coding RNA' regulating tau protein production, a crucial mechanism for brain cell function. The discovery may lead to new treatments for dementia-related diseases, including Parkinson's and Alzheimer's.
Researchers at University College London developed a robotic 'Third Thumb' that allows users to perform dextrous tasks with one hand. The study found that participants' brains adapted to the extra thumb, changing their natural hand movements and reporting it felt like part of their body.
A new study led by UCL researchers suggests intensive agriculture could drive loss of bees and other tropical pollinators. Insect pollinators were found to be more than 70% less abundant in areas with intensive cropland compared to wild sites.
Scientists at UCL have identified a new immunotherapy that targets acyl-CoA:cholesterol acyltransferase (ACAT), an enzyme helping to manage cholesterol levels in cells. Boosting ACAT inhibition boosts specific immune cells fighting both the virus and cancerous tumours, demonstrating its effectiveness as an immunotherapy.
A large-scale trial of annual screening for ovarian cancer found that neither method reduced deaths from the disease, contradicting expectations. Early detection strategies detected cancers earlier, but this did not translate into saving lives.
A new study found that almost half of women with babies under six months old met the threshold for postnatal depression during the first COVID-19 lockdown. Social isolation and lack of support were significant contributors to this increased risk.
Researchers developed a gene therapy that successfully treated 48 out of 50 children with ADA-SCID, a rare life-threatening disease. The treatment involves removing stem cells, delivering a new copy of the ADA gene, and returning the corrected cells to produce healthy immune cells.
A groundbreaking study has identified IL-17 cytokine as the primary culprit behind excessive lung inflammation in TB patients. By targeting this pathway, doctors may be able to reduce disease harm and speed up patient recovery.
A recent study led by University College London researchers has found that mild COVID-19 infections do not lead to lasting heart damage. The study of 149 healthcare workers with mild COVID-19 infections showed no significant differences in heart structure or function compared to healthy controls.
London's low-income households face higher levels of indoor air pollution due to poor housing quality and surrounding environmental factors. Long-term exposure to pollutants like PM2.5, NOx, and CO can lead to health problems such as respiratory issues and cardiovascular complications.
A new simulation study led by UCL researchers suggests that studying black hole-neutron star collisions could provide a new measurement of the Universe's expansion rate, helping to resolve a long-standing dispute. The study found that instruments on Earth could detect ripples in space-time caused by up to 3,000 such collisions by 2030.
A review of over 500 academic papers found that wasps are valuable for agriculture, providing biocontrol services worth $416 billion annually. Wasps also contribute to pollination, visiting 960 plant species, including those dependent on them for reproduction. Their venom and saliva have medicinal properties.
Researchers used AI to identify three new MS subtypes based on brain images, which can help predict disease progression and treatment response. The study found a clear difference in patients' response to different treatments by subtype, paving the way for individualized treatment planning.
A single qubit on a standard silicon transistor chip has been successfully demonstrated as 'quantum capable' in a new study. The researchers were able to isolate and measure the quantum state of a single electron in a silicon transistor manufactured using existing manufacturing processes.
A study found that metformin successfully reduced symptoms associated with tuberous sclerosis complex, including a 44% drop in seizure frequency and a 21% reduction in brain tumour size. Researchers believe this could improve quality of life for TSC patients.
Research finds that global awareness of biodiversity is growing, but its value is poorly measured. The Species Awareness Index tracked changes in Wikipedia page views from 2015 to 2020, revealing faster increases for certain species like reptiles and the long-tailed tit.
A study found that gene therapy can create a long-term store of correct T cells in the human thymus, leading to sustained health in patients with SCID-X1. The treatment works by delivering corrected genes into stem cells, which then produce healthy immune cells.
A UK study found that the SARS-CoV-2 variant B.1.1.7 spread rapidly in care homes across England, reflecting its rapid growth in the general population. The proportion of infections caused by this variant increased sharply between late November and December, with a notable rise among older residents.
The Antikythera Mechanism, a 2,000-year-old device used to predict astronomical events, has a newly recreated gearing system that conforms to physical evidence and matches descriptions on the Mechanism. The team recovered cycles for all planets using an ancient Greek mathematical method.
A new study suggests that targeted screening for prostate cancer could prevent up to 16% of prostate cancer deaths and reduce overdiagnosis by 27%. The study, led by UCL researchers, recommends screening men with a high genetic risk profile using an MRI scan before biopsy.
A recent study published in Annals of Clinical and Translational Neurology found that head injuries in people under 50 can lead to lower cognitive scores at age 70. The researchers discovered a small but significant impact on brain health and thinking skills, potentially accelerating the normal aging process.
A new study found that 58% of healthcare workers met the threshold for any mental health disorder, with 22% experiencing post-traumatic stress disorder. The research highlights the need for immediate additional mental health support and long-term planning to meet staff needs.
A large-scale trial found that daily albumin infusions provide no significant health benefit to patients hospitalised with advanced liver disease, over and above 'standard care'. The study showed no reduction in infection, kidney dysfunction, or death among patients receiving targeted albumin treatment.
Scientists at UCL and George Mason University have located the source of potentially hazardous solar particles for the first time, finding they originate from plasma confined close to the top of the Sun's chromosphere. This discovery aims to improve forecasts of solar storms and reduce risks to satellites and electronic infrastructure.
Researchers have developed a temporary tattoo using organic light-emitting diodes (OLEDs) that can emit green light. The technology has the potential to be combined with other electronics for various applications, including fashion, sports, and healthcare, such as detecting dehydration or signaling expiry dates.
Research from UCL found a surprising synchronicity between car accidents and violent crimes in Mexico City, revealing 'heartbeats' of the city that peak in the evening. Improving road safety could improve crime prevention and give more resources to police tackling crime.
A new study published in Nature Communications shows that genetic mutations during embryonic development can cause spina bifida, a severe birth defect. Researchers found that even when these mutations occur randomly in only 16% of spinal cord cells, it's enough to lead to spina bifida.
A new study published in Psychological Medicine found that boys who regularly play video games at age 11 are less likely to develop depressive symptoms three years later. In contrast, girls who spend more time on social media appear to develop more depressive symptoms. The study suggests that different types of screen time can positive...
Researchers developed a new X-ray imaging scanner that provides surgeons with a full 3D image of extracted tissue lumps, allowing for improved detection of diseased tissue. This technology has the potential to significantly reduce the need for repeat operations in breast cancer patients.
A new study found that lesbian, gay, and bisexual (LGB) individuals are more likely to experience mental health conditions and report alcohol and drug misuse than heterosexuals. The research analyzed data from the Adult Psychiatric Morbidity Surveys and found no improvement in disparities between 2007 and 2014.
A new drug, semaglutide, has been shown to cut body weight by 20% in a major global study involving over 1,900 participants. The study, published in the New England Journal of Medicine, found that three quarters of people who received the drug lost more than 10% of their body weight.
A UCL-led team discovered 32 gene regions affecting facial features such as nose and lip shapes. The analysis of over 6,000 volunteers found that one gene, TBX15, was inherited from the Denisovans, an extinct group of ancient humans.
A recent study by University College London researchers found that people living in areas with high levels of air pollution, particularly fine particulate matter, are at increased risk of developing AMD. The study suggests that improving air quality could be a key public health priority to reduce the risk of eye disease.
Researchers link magnetic waves in chromosphere to areas of abundant ionised particles in hot outer atmosphere, explaining the Sun's unique chemical make-up. The discovery provides a foundation for understanding the solar wind and its impact on Earth.
Researchers found that people with Parkinson's disease who have visual problems are more likely to develop dementia, with underlying changes in brain wiring explaining the connection. Vision tests may provide a window of opportunity to predict Parkinson's dementia before it begins.
Researchers developed an online risk-stratification tool to predict COVID-19 patients' likelihood of deterioration, using 11 measurements including age, oxygen levels, and laboratory tests. The '4C Deterioration Score' provides clinicians with a percentage risk score to support decision-making and potentially save lives.
A new UCL study found that combining heat treatment with chemotherapy delivered via magnetic nanoparticles killed cancer cells more effectively than chemotherapy alone. The therapy showed synergistic effects, enhancing the effectiveness of both treatments when combined. Heat treatment can reduce side effects by targeting only cancer ce...
Researchers at UCL developed a pioneering new eye test called DARC that can predict wet age-related macular degeneration (AMD) three years before symptoms appear. The test uses a fluorescent dye to detect stressed retinal cells, which then predicts future AMD activity.
Researchers investigated COVID-19 and Guillain-Barré syndrome, a rare autoimmune condition. The study found no significant association between the two conditions, contradicting previous small case series. The researchers conclude that COVID-19 vaccination is unlikely to cause GBS.
A study led by UCL researchers found that flightlessness evolved in birds at least four times as often as expected. With 166 extinct species lacking flying ability, the findings show how human-driven extinctions have biased our understanding of evolution, altering most ecosystems worldwide.
A new study found that cancer drug treatment registrations in the UK increased by June 2020, following 'rapid' NHS guidance. The initial decrease in April was largely reversed by May and June, with a significant increase in neoadjuvant breast cancer therapy registrations.
A novel CAR T-cell therapy has shown promising early results in children with relapsed or refractory neuroblastoma. The treatment induced rapid reduction in tumor size, but effects were transient. Researchers are optimistic about the potential of this immunotherapy as a future treatment for solid cancers in children.
A study of SARS-CoV-2 virus genomes from over 46,000 people with COVID-19 found that most common mutations are neutral for the virus, and do not appear to increase transmissibility. The research team identified 12,706 mutations, including one in the spike protein D614G, which is not associated with increased transmission.
A new study by UCL researchers used quantum sensing abilities of nanodiamonds to improve the sensitivity of paper-based diagnostic tests, enabling earlier detection of diseases such as HIV. The tests can detect lower viral loads and may be adapted for COVID-19 and other diseases.