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University of California - San Diego


HIV and a tale of a few cities

Researchers studied the impact of public health-oriented drug law reforms on HIV incidence among people who inject drugs in Tijuana, Mexico. Implementing reforms could prevent 21% of new HIV infections if incarceration is reduced and individuals are diverted to evidence-based treatment.

SourceUniversity of California - San Diego·JournalThe Lancet Public Health·DateAug 17, 2018

Researchers turn powerful, viscous disinfectants into breathable mist for the first time

A team of engineers and physicians at the University of California - San Diego developed a device that diffuses potent disinfectants for airborne delivery. The device effectively eliminated bacteria commonly causing hospital-acquired infections and also killed highly multi-drug resistant strains of bacteria including K. pneumoniae.

SourceUniversity of California - San Diego·JournalApplied Microbiology and Biotechnology·DateAug 1, 2018

Why are neuron axons long and spindly? Study shows they're optimizing signaling efficiency

Researchers at UC San Diego have found that axon geometry is crucial in information flow, with a 'refraction ratio' of 0.92 indicating optimal balance between signal latency and refractory period. This discovery has implications for understanding neurological disorders like autism and developing more brain-like artificial neural networks.

SourceUniversity of California - San Diego·JournalScientific Reports·DateJul 11, 2018

Biosensor chip detects single nucleotide polymorphism wirelessly, with higher sensitivity

A team at the University of California San Diego has developed a wireless chip that can detect genetic mutations, including single nucleotide polymorphisms (SNPs), in real-time. The chip is at least 1,000 times more sensitive than current technology and could lead to cheaper, faster, and portable biosensors for early disease detection.

SourceUniversity of California - San Diego·JournalAdvanced Materials·DateJul 9, 2018

CAR-T immunotherapies may have a new player

Researchers at University of California San Diego School of Medicine and University of Minnesota have developed a new CAR-T immunotherapy using natural killer cells engineered from human induced pluripotent stem cells. These cells demonstrated heightened activity against ovarian cancer with less toxicity, offering potential advantages ...

SourceUniversity of California - San Diego·JournalCell Stem Cell·DateJun 28, 2018

A sprinkle of platinum nanoparticles onto graphene makes brain probes more sensitive

Researchers at UC San Diego developed a technique to engineer graphene electrodes with low impedance and transparency. This allows for simultaneous recording of neuronal activity and high-quality imaging of brain cell activity in transgenic mice. The technology brings graphene electrodes closer to being adapted into next-generation bra...

SourceUniversity of California - San Diego·JournalAdvanced Functional Materials·DateJun 14, 2018

Phase I trial finds experimental drug safe in treating chronic lymphocytic leukemia

Researchers at the University of California San Diego School of Medicine have found that treatment with cirmtuzumab measurably inhibited the 'stemness' of CLL cells, allowing most patients to forego additional therapy for over eight months. The drug targets ROR1, a molecule exploited by cancer cells to promote tumor growth and spread.

SourceUniversity of California - San Diego·JournalCell Stem Cell·DateJun 1, 2018