Researchers validated clinical feasibility of a low-cost, CRISPR-based diagnostic platform using COVID-19 clinical swab samples. The method enables simple, rapid, and ultrasensitive detection of SARS-CoV-2 with results visible by the naked eye within 20 minutes.
Researchers found that households in states with Medicaid expansion increased purchase of diet soda and bottled water but showed no change in regular soda consumption. The study suggests a spillover effect of the program promoting healthier dietary choices.
A recent study published in the American Journal of Preventive Medicine found that COVID-19 prevention messages are less effective when attributed to President Donald Trump. Researchers found that even participants who trust Trump did not find his messages more effective compared to other sources.
A study by UConn School of Nursing researchers found that strong feelings of germ aversion and pathogen disgust are significantly associated with concern about COVID-19 and increased engagement in preventative health behaviors. Individuals who indicated higher levels of psychological disease avoidance also reported greater concern for ...
Researchers successfully inhibited the P2X4 receptor, which plays a significant role in post-stroke damage and recovery. The study shows that short-term inhibition of this receptor can regulate immune cell activation and improve both acute and chronic stroke recovery.
Researchers found that high CO2 concentrations in water make fish grow smaller, with a growth deficit of between five and ten percent. Fish living at less ideal temperatures and more CO2 experienced greater reductions in growth.
A nationwide survey of academic neurologists reveals that bad outcomes from stem cell tourism are much more common than realized, with complications including infections, strokes, spinal tumors, seizures, and even deaths. Many neurologists feel ill-equipped to warn patients about the dangers of unproven treatments.
Researchers from UConn and Wesleyan University found high levels of mercury in the Still River, exceeding EPA guidance levels for weekly consumption. The study suggests that legacy mercury pollution is persisting in the environment and impacting the food web, with bioavailable forms posing a significant health risk to humans and wildlife.
Researchers at UConn Health have developed a non-invasive biomarker panel for diagnosing and monitoring infant urinary tract obstruction. The panel of five proteins can detect UPJO in infants and toddlers, reducing the need for expensive and invasive tests.
A team of international researchers found that evolution tends to dampen or smooth out variations in ecological patterns across landscapes. The study, published in the Proceedings of the National Academy of Sciences, analyzed over 500 studies and identified 14 mechanisms affecting the direction of evolution's impact.
A team of UConn engineers has developed a scaffold that generates a controllable electrical field to encourage bone growth, providing a new approach for treating serious injuries. The device uses non-toxic poly(L-lactic acid) polymer and remotely-controlled ultrasound to stimulate bone regeneration.
Researchers study rituals as a mechanism of resilience against anxiety, finding that performing familiar rituals reduces psychological and physiological stress. This approach suggests that ritual provides the brain with a sense of control and structure, alleviating stress and potentially coping with chronic anxiety.
Scientists successfully deliver healthy mitochondrial complexes to liver cells in rats, offering a new approach for treating liver diseases. The method, which uses a protein coating to target mitochondria to the liver, shows promise for addressing a significant gap in current treatments.
UConn researchers use patented nanoparticle with common chemotherapy drug doxorubicin to target leukemia stem cells, reducing treatment-resistant relapses. The nanoparticle enables slow release of the drug to bone marrow, improving survival rates and inhibiting cancerous stem cells.
Researchers at UConn's CEVR have made a breakthrough in vaccine development for Mycoplasma pneumoniae, a common and difficult-to-treat pneumonia-causing pathogen. By identifying the cause of vaccine-enhanced disease (VED), they were able to develop a new vaccine formulation that eliminates safety concerns.
Researchers have developed a novel portable pyroelectric technology that converts waste heat into usable power, offering a clean alternative to fossil fuels and nuclear energy. The technology has an extended lifetime and uses on-chip combustion of methanol to harness energy.
Researchers are developing a patient-friendly smartphone sensor to measure tooth pain and provide accurate care. The grant aims to test a novel way to quantify tooth pain using a commercially available device and miniaturize it for smartphone use.
A UConn study found that most Americans are experiencing stress related to COVID-19, but also adhering to social distancing guidelines. The survey showed high stress exposure and vulnerable demographic groups, with younger adults and men showing potentially worrisome lack of adherence to CDC guidelines.
Researchers found that gesturing while speaking affects the sound of a person's voice, adding acoustic emphasis. The study suggests that gestures carry additional information about bodily tension and motion, contradicting traditional views on language.
A study suggests a species of beetle could help control an invasive weed at the root of many people's suffering from seasonal allergies. Biological control may reduce the number of people affected by ragweed pollen and associated health costs in Europe.
A recent study by UConn researchers found that mismanagement and inadequate infrastructure are the root causes of supply problems for Ugandan farmers. The study revealed discrepancies in the quality of agricultural supplies like seeds and fertilizers due to improper handling, not adulteration.
Researchers are investigating how individual factors influence engagement in preventative health behaviors during the COVID-19 pandemic. The yearlong study assesses preventative behaviors, social attitudes, and individual differences to inform future pandemics or viral threats.
Researchers discovered that a single soft x-ray can destroy a protein-sized molecule by inducing radiation damage in neighboring atoms. The findings could lead to safer medical imaging and a better understanding of heavy metals' electronic properties.
Researchers at UConn School of Dental Medicine have discovered a population of stem cells residing along vascular channels in bone that can generate new bone-forming cells. These perivascular cells may regulate bone formation and participate in bone mass maintenance.
Research shows that microplastics are damaging to coral ecosystems, causing significant reductions in population size and cell size. The exposure of endosymbionts to microplastics led to elevated stress levels and reduced detoxification activities, highlighting the importance of minimizing plastic use to preserve the environment.
A new study finds that domestication of plants fostered cooperation among people, but also saw the rise of organized intergroup violence. As farming developed, groups aggregated and lived cooperatively in high-quality locations, but this led to a spike in trophy-taking violence.
A new study has shed light on why the world's oceans are home to an astonishing array of species, with slow and steady evolution playing a key role in their diversity. The research analyzed over 20,000 fossil marine animals and found that ecologically flexible groups tend to be more resistant to extinction.
A recent study published in Drug Metabolism and Disposition found that mice with drug-induced liver damage can safely take medications for diabetes, hypertension, and depression at lower doses. This breakthrough suggests that people with damaged livers may be able to continue taking life-saving medications while healing.
Researchers developed a handheld 3D bioprinter to treat volumetric muscle loss, allowing for direct scaffold deposition into defect sites. The bioprinter prints gelatin-based hydrogels that mimic native tissue properties and adhere precisely to surrounding tissues.
Researchers discovered that the monkeyflower's distinctive spots are controlled by a reaction-diffusion mechanism involving two proteins. The study used mathematical modeling and experimentation to validate the theory, shedding light on how natural patterns arise.
A new lensless on-chip microscopy platform developed at UConn removes traditional lenses to provide a fuller picture of tissue samples, leading to more accurate diagnoses. The platform uses ptychography and achieves an ultra-high Fresnel number, allowing for a 30 mm2 field of view and eliminating the need for cell staining.
A 'smart' bandage developed by UConn engineers can precisely deliver different medications to chronic wounds, promoting healing and reducing morbidity. The wirelessly-controlled bandage is equipped with miniature needles that can penetrate deeper layers of the wound bed with minimal pain and inflammation.
New research shows that feeding bluebirds can significantly impact parasitic nest flies and improve nestling survival. The study found that supplementing birds with food reduces the parasite load and improves antibody levels, which help kill the parasites. The timing of feeding is also crucial, with early feeding benefiting young birds...
A four-year project examined how schools use screening tools and factors influencing their use. The study found that school leader knowledge and attitudes are key to proactive screening approaches, leading to better outcomes for students.
Expanding Medicaid in North Carolina would reduce colon cancers and improve access to care for men of all races, saving thousands of Black male lives. The study found that the state would save $5.1 million in cumulative cost savings by 2044.
Researchers at UConn have discovered that transplanting healthy donor bone marrow cells into mice with OI can improve bone strength and structure. The study found that these cells can replace mutant collagen and increase bone mass, offering potential for new therapies to correct the disorder.
A study found that popular gym chains offer tanning beds in over 78% of their locations, despite public health warnings about the dangers of indoor tanning. Gyms are undermining health by marketing tanning beds to physically active people who are at increased risk for melanoma.
Researchers at UConn's Ecology and Evolutionary Biology Department shed new light on the evolution of the treehopper's distinctive helmet. By analyzing RNA sequences, they found that the gene expression lines up with wings rather than the dorsal body wall, suggesting a unique developmental pathway.
UConn researchers have discovered a connection between pregnancy and cancer metastasis in various mammal species. They found that certain species have evolved to make their stromal cells highly resistant to invasion, unlike humans who are more vulnerable to cancer metastasis.
Researchers have identified a splicing factor called TRA2B as a key driver of triple negative breast cancer's ability to grow and spread. Blocking TRA2B expression in cells has been shown to prevent metastasis, providing a potential new treatment avenue for this devastating form of breast cancer.
Acinetobacter baumannii is a highly resistant bacteria that causes persistent skin and soft tissue infections. Researchers are investigating the use of selenium as an antimicrobial agent, which has shown promise in inhibiting bacterial virulence.
Nami Therapeutics develops nanoparticles for targeted drug delivery, offering increased efficacy and reduced toxicity. The platform selectively targets ovarian cancer metastasis in the peritoneal cavity, improving survival rates.
Researchers developed a theory that sheds light on detonation formation at the heart of supernovae explosions, demonstrating the process using experiments and numerical simulations. The study predicts the conditions for detonation formation in Type Ia supernovae, providing insight into fundamental aspects of physical processes.
Opioid overdose deaths in Connecticut more than doubled between 2012 and 2018, driven by increased use of multiple drugs. The study found that fentanyl-related deaths often involved at least one other drug, highlighting the need for new prevention and intervention strategies.
Researchers discovered evidence of controlled fire in Lusakert Cave 1, contradicting the long-held notion that Homo sapiens were the first to master fire. The team used archaeological, hydrocarbon, and isotope analysis to determine the age of fire control among early humans.
A new study found a fourfold increase in the use of cardiopulmonary resuscitation (CPR) devices among emergency medical technicians in the U.S. over a six-year period, despite minimal evidence of their effectiveness. The devices were used more often outside of hospitals, with a steep rise from 2% to 8% between 2010 and 2016.
Research analyzed over 275,000 restaurant reviews to find differences in reader perception based on the platform where reviews were generated. Mobile reviews were associated with lower likes and consumption value compared to laptop or desktop reviews.
A major study published in Circulation shows that more aggressively controlling daily blood pressure in older adults can improve brain health by reducing the accumulation of white matter lesions. Researchers found that intensive blood pressure therapy reduced these lesions by up to 40% and lower cardiovascular events, making it a safer...
Research found that shoppers who win discounts through promotional games make a purchase and spend more money than those offered standard discounts. Games increase the likelihood of buying, leading to higher sales and long-term profitability for retailers.
A new study finds that copepods, small crustaceans found in nearly every freshwater and saltwater habitat, adapt to warming waters through phenotypic plasticity rather than genetic changes. The research suggests that thermal adaptation can happen relatively quickly, reducing organisms' vulnerability to warming.