Professor Lutz Nuhn aims to create lipid-free capsules for RNA vaccines that don't require cooling and can initiate precise immune responses. He plans to equip the capsules with messenger substances to target cancer as well.
Researchers have made significant progress in understanding ancient Egyptian writing practices in the Fayum Basin, with a focus on temple administration and cultural exchange. The study has shed light on the importance of Greek language in Egypt during the Ptolemaic and Roman periods.
University of Würzburg researchers Hermann Einsele, José Pedro Friedmann Angeli, Ronny Thomale, and Christoph Wanner have been named Highly Cited Researchers by Clarivate Analytics. Their work in medicine and cell biology has garnered significant attention, with Einsele's research on cancer immunotherapy and Angeli's studies on ferropt...
Researchers have discovered a new pathway for selenoprotein production, led by PRDX6, which can sustain selenium protein synthesis. Inhibiting PRDX6 may impair cancer cell survival, particularly in neuroblastomas, offering a new therapeutic target.
A German-French research team has been awarded an 11 million euro ERC Synergy Grant to develop an AI-based solution for the systematic search of new antibiotics. The team aims to analyze seven bacterial species and their genetic mutants using advanced methods, including deep learning analyses, to identify potential new antibiotic agents.
Plant guard cells use calcium signals to regulate stomatal movement in response to environmental stimuli. By counting up to six consecutive calcium transients, guard cells can close their stomata and conserve water.
A new study found that interacting with virtual agents designed to resemble people with a migration background can increase trust in the police. The study showed that virtual agents are an effective tool for positive personal interaction with authorities, and their use could be a cost-effective solution for police forces.
Researchers at the University of Würzburg discovered that plants use an energy-saving mechanism to adapt their potassium uptake based on soil conditions. By building a pH gradient across cell membranes, plants can transport potassium into cells without expending energy.
Researchers found that light pollution disturbs moth behavior outside the illuminated area, causing them to fly in curvy paths. The study also revealed an interaction between artificial light and the moon's phase, affecting moths' orientation and flight patterns.
Researchers explore the influence of digital resources on autobiographical memory, highlighting its potential benefits, such as supporting people with memory difficulties, and risks, like manipulation through deepfakes. The study aims to better understand the interplay between recorded data and memories stored in our minds.
A new mechanism of DNA damage response has been identified, involving an RNA transcript that regulates genome stability. The study found that NEAT1, a long non-coding RNA transcript, plays a crucial role in recognizing and repairing DNA double-strand breaks.
Researchers at Würzburg University have developed a method to experimentally test the AdS/CFT correspondence, a central theory of quantum gravity. The approach uses a branched electrical circuit to mimic curved spacetime and demonstrates that it can realize gravitational dynamics.
Jakob Zimmermann is receiving a total of 1.6 million euros from the European Research Council (ERC) to study T-cell immune memory in the intestine and its connection with intestinal flora, aiming to develop new treatments for chronic inflammatory bowel diseases and vaccines.
A team of Würzburg researchers is using a swarm of autonomous robots to explore the Martian canyon system, Valles Marineris. The robots will collect data on the canyon's geology and search for signs of liquid water and potentially life, shedding light on the planet's habitability.
A research team at the University of Würzburg has achieved electrically controlled modulation of light antennas, paving the way for ultra-fast active plasmonics. This breakthrough could lead to significantly faster computer chips and new insights into energy conversion and storage technologies.
Research found that combining neonicotinoids with fungicides significantly increased mortality of bee larvae, while also affecting adult honeybee survival rates and lifespan. The study suggests that solitary wild bees may be more vulnerable to pesticide effects due to their smaller colony size.
Researchers find that heatwaves significantly impair bumblebees' ability to detect floral scents, leading to up to 80% deterioration in female workers. The study highlights the importance of considering climate change's impact on insect-plant interactions for future species conservation initiatives.
Scientists have created a new chemical probe to visualize the distribution of sphingomyelin and its degradation by sphingomyelinase during infections. The researchers observed increased metabolization of sphingomyelin molecules during Chlamydia infection, paving the way for targeted strategies against infectious diseases.
The study reveals that light-sensitive channels can be used to target specific ion signals in plants, allowing for the comparison of different signaling pathways. This breakthrough enables researchers to investigate plant stress responses in greater detail.
Researchers found that Chlamydia bacteria can persist in the intestines of humans, where they form a permanent reservoir and evade antibiotic treatment. The bacteria preferentially infect the inner cell layer of intestinal organoids, but not the outer epithelial layer.
Researchers confirm Kagome superconductor, a class of materials with star-shaped structure exhibiting unique electronic, magnetic, and superconducting properties. The discovery enables novel electronic components, such as superconducting diodes, with potential for energy-efficient quantum devices.
A new research consortium aims to improve the reliability of machine learning systems by using geometric methods to prevent adversarial attacks. The project, GeoMAR, will explore ways to feed neural networks with erroneous data during training to prepare them for real-world scenarios.
Researchers are exploring the use of CRISPR Prime Editing to optimize CAR-T cells for treating multiple myeloma and other cancers. The goal is to improve effectiveness, duration, and cost-effectiveness of CAR-T cell therapies.
A new study published in Nature Medicine found that people rate medical advice as less reliable and empathetic when an AI is believed to be involved. Despite this, respondents were still less willing to follow AI-supported recommendations compared to advice from human doctors.
Researchers have developed a novel light-harvesting system that can absorb the entire visible light spectrum, similar to natural systems. The system uses a unique arrangement of four different dyes and converts 38% of irradiated light energy into fluorescence.
A new study examines the economic effects of sanctions on Iran and Russia, finding significant declines in GDP and prosperity. The researchers propose transferring funds to mitigate welfare losses among participating countries, suggesting a more effective approach to sanctioning.
Researchers at the University of Würzburg have discovered a natural substance that can inhibit vitamin B6 degradation, increasing its levels in nerve cells involved in learning and memory processes. This compound, 7,8-Dihydroxyflavone, has been linked to improved spatial learning and memory capacity in mice.
The study reveals that the binding sites of USP28 and USP25 inhibitors are identical, leading to non-specific effects. Researchers now aim to develop precise inhibitors targeting either enzyme site to reduce side effects.
Researchers are uncovering daily life in ancient India through newly analyzed Proto-Sarada inscriptions, including administrative documents and clay seals. The project aims to create a comprehensive edition of these inscriptions, shedding light on the social, economic, and cultural history of pre-modern South Asia.
Asteroid Apophis is expected to come extremely close to Earth on April 13, 2029, offering a rare opportunity for research. The NEAlight project aims to investigate three concepts for German small satellite missions to study the asteroid's trajectory and structure.
Researchers caution that current AI-based deception detection methods are plagued by a lack of explainability, risk of biased results, and deficits in theoretical foundation. They emphasize the need for controlled laboratory experiments, large and diverse data sets, and validation on independent datasets to ensure accurate results.
Researchers developed a new measurement method that significantly improves the accuracy of electrical resistance measurements, leveraging the Quantum Anomalous Hall Effect. The method allows for precise measurements at high currents and without an external magnetic field, making it suitable for advanced applications.
Researchers have shed light on the complex communication between cells at the gastro-esophageal junction, revealing specific pathways and cellular composition. The study provides new starting points for understanding, preventing, and treating gastrointestinal diseases.
A team of international researchers has developed a hybrid device combining a stable proximitized-superconductor with magnetism, allowing precise control over its properties. This innovation could lead to significant advancements in quantum computing by stabilizing quantum bits and overcoming external influences.
Researchers have experimentally verified the parity anomaly in a topological insulator, which leads to spectral asymmetry and an unusual change in electrical resistance. This finding is generic for any topological insulator and opens up new avenues for exploring topological insulator physics.
Researchers aim to create a nuclear clock using thorium isotopes, which could increase measurement accuracy by a factor of 3. The project uses light with orbital angular momentum to excite the nucleus, emitting photons that can be detected. This technology has the potential to answer fundamental questions in physics and astronomy.
Researchers at University of Würzburg successfully crafted a functional protective layer for indenene, a two-dimensional quantum semiconductor material. The graphene-based coating protects the material from oxidation and corrosion, enabling its use in air or chemical environments.
A new project, NaKlaR, aims to improve the efficiency and sustainability of sodium-ion batteries by optimizing production processes and recyclability. The goal is to develop a battery with performance comparable to current reference cells while containing at least 25% recycled electrode material.
A new study aims to develop a treatment for osteoarthritis by regenerating cartilage using nasal cartilage tissue. The method has already shown promising results in smaller studies, with the goal of providing an alternative to prostheses and improving patient outcomes.
Desert ants of the Cataglyphis genus possess abilities that distinguish them from other creatures: they can orient themselves to the Earth's magnetic field. Researchers discovered this and found it is primarily processed in the ant's internal compass and mushroom bodies. The study shows that information about the magnetic field serves ...
Researchers at JMU found that low-energy quasiparticles in copper oxide superconductors are resilient against extreme disorder due to quantum entanglement. This ability allows them to move through the system unaffected by impurities, unlike normal electrons.
A team of scientists has found that 7-dehydrocholesterol (7-DHC) integrates into cell membranes and prevents ferroptosis, increasing cellular fitness and potentially promoting aggressive cancer behavior. This discovery could lead to the development of new cancer treatments targeting cholesterol biosynthesis.
Researchers aim to decipher function and structure of 1,000 RNA-binding proteins involved in mRNA transport. They hope to gain insights into mRNA stability, relevant to new vaccine development and cancer research.
Matabele ants can recognize infected wounds and effectively treat them with their own produced antibiotics, drastically reducing mortality. The ants' sophisticated healthcare system has medical implications for humans, as the primary pathogen in ant wounds is also a leading cause of infection in humans.
Researchers discovered that dragonflies change their average coloration seasonally, with darker colors absorbing heat and lighter colors protecting against overheating. This adaptation allows them to regulate their body temperature in response to changing solar radiation conditions.
Researchers have identified a previously unknown endogenous acid sensor in plant cells that responds to changes in pH levels. The acid sensor triggers the release of calcium ions from an endoplasmic reticulum, which activates cellular responses to external stimuli such as infections or drought.
A new statistical method developed by the DFG research group BETA-FOR can analyze the contributions of biodiversity between local ecosystems to the multifunctionality of entire landscapes. The study breaks down multifunctionality into two components, relating them to local biodiversity and habitat diversity.
Researchers discovered how Vγ9Vδ2 T cells recognize pathogens and cancer cells by their altered cell metabolism. The study found that phosphoantigens bind to special molecules inside the cell, triggering a signal to kill. This finding can improve the clinical use of Vγ9Vδ2 T cells in tumor treatment.
Researchers have developed PicoRulers, biocompatible molecular rulers for high-resolution microscopy. Using genetic code expansion and click chemistry, the team constructed customized molecular rulers based on the protein PCNA, enabling precise testing of super-resolution microscopy methods on cellular biomolecules.
Researchers found an inverse relationship between axon loss and demyelination, suggesting that 'bad' myelin can be more damaging than its absence. This study identifies potential therapeutic targets for diseases associated with myelin defects and inflammation in the nervous system.