Research on identifying and measuring risk. Covers rock-avalanche modeling, cardiovascular risk, food-toxin safety, and heart calcium scans.
Scientists at UKCEH developed a robust method to detect and measure toxic chemical 6PPD in river sediments, which has been linked to salmon and trout deaths. The method uses gas chromatography mass-spectrometry techniques to accurately quantify 6PPD concentrations.
A new American Heart Association scientific statement offers the latest knowledge on neurodevelopmental outcomes in people of all ages with congenital heart disease. The statement highlights that neurodevelopmental difficulties are common complications faced by individuals with congenital heart disease, affecting their ability to funct...
Researchers at UCSF used clinical data and a precision medicine approach to identify early risk factors for Alzheimer’s disease, predicting its onset with 72% accuracy. High cholesterol, osteoporosis, and erectile dysfunction were found to be predictive factors in both men and women.
A new study links climate change to a 60% increase in preterm births and severe respiratory diseases. Without global action, climate-driven extremes will devastate children's health for generations, with the strongest link found between temperature extremes and increased risk of preterm birth.
Men with low sperm count or none have a higher risk of developing cancer, including at younger ages, compared to fertile men. Families of azoospermic men have a significantly increased risk of five cancers, while families of oligozoospermic men have a higher risk of colon, bone and joint, and testicular cancers.
A new study from the University of Toronto found that older Canadians with a history of stroke experienced depression during the COVID-19 pandemic. Among those with no lifetime history of depression, immigrant status and family stressors were associated with an increased risk of incident depression.
A new study from Edith Cowan University found that a blood test using joint cumulative high-sensitivity C-reactive protein and monocyte to high-density lipoprotein ratio can predict type 2 diabetes risk more effectively. Females were most at risk with significant interaction between MHR and CRP observed.
A new study reveals that utilization of PCSK9 inhibitors is low among high-risk patients, despite extensive evidence documenting their role in LDL-C reduction and the prevention of heart attacks. The study found that insurance coverage rejection or abandonment leads to significantly more cardiovascular events within 12 months.
Males with anorexia nervosa have a sixfold higher mortality rate than the general population. Early identification and prompt treatment are essential for effective management of the condition.
Researchers found six pesticides and related compounds in kale from small farms in Maryland, but levels were much lower than a concern. The study provides insight into the safety of farm-raised greens and will help identify health risks associated with other fruits and vegetables.
A new study published in Radiology found that annual breast cancer screening beginning at age 40 and continuing until 79 results in the highest mortality reduction. The study analyzed Cancer Intervention and Surveillance Modeling Network (CISNET) estimates and showed that annual screening reduces breast cancer deaths by 41.7%.
Researchers optimized polygenic risk scores using ancestrally diverse genomic data to improve accuracy across diverse populations. The recalibrated tests provided a more accurate assessment of disease risk for individuals with varied ancestral backgrounds.
A recent study found that a commercial machine learning tool was moderately successful in predicting hospitalization-related kidney injury, but struggled to identify high-risk patients. The tool performed better for low-risk patients and Stage 1 HA-AKI cases.
A study co-led by Prof. Kelly Metcalfe finds risk-reducing mastectomies significantly reduce breast cancer risk and death probability in women with a BRCA1 or BRCA2 genetic variant. The procedure reduces the risk of breast cancer by 80% and decreases mortality to less than 1%.
A new study by Norwegian University of Science and Technology has developed a tool to identify individuals at high risk of burnout. The Burnout Assessment Tool (BAT) measures four main groups of risk factors, including exhaustion, mental distancing, cognitive impairment, and emotional impairment.
Researchers analyze how companies use feminist narratives to promote unscientific tests and treatments for women, often with uncertain effectiveness. This marketing behavior risks harming women, contributing to overdiagnosis and overtreatment.
Researchers identify a promising prognostic biomarker for lung cancer using circulating tumor DNA-based minimal residual disease detection. The study found that this method can effectively guide treatment decisions and predict recurrence risk, potentially modifying the lung cancer treatment paradigm.
Researchers document various reasons for long-term clinical symptoms in patients infected with SARS-CoV-2. Key findings include immune system alterations, chronic inflammation, endothelial dysfunction, and mitochondrial issues contributing to post-COVID syndrome.
Two new EU-funded projects, PollinERA and WildPosh, will investigate the toxicological and ecological impacts of chemical pollution on terrestrial biodiversity and pollinators. The projects will improve risk assessment tools and characterise exposure routes to pesticides in four European regions.
A new American Heart Association scientific statement emphasizes the need for increased awareness of heart disease as a major health risk for women, particularly those with pregnancy complications. Early detection and treatment of risk factors may help prevent future heart attack, heart failure, and stroke.
A recent study published in The Journal of Bone & Joint Surgery suggests that robotic-assisted surgery and surgical navigation techniques do not significantly increase the risk of periprosthetic joint infection (PJI) after total hip arthroplasty (THA). The researchers analyzed data from nearly 13,000 patients undergoing THA between 201...
A new study found that physical activity levels are insufficient to counter the increased risk of cardiovascular disease associated with consuming sugar-sweetened beverages. Even moderate consumption can lead to higher cardiovascular disease risk, emphasizing the need to limit these drinks' omnipresence in the food environment.
A new blood test developed by Indiana University School of Medicine has identified biomarkers that can objectively measure schizophrenia severity and predict future risk. The test enables personalized treatment matching, reducing uncertainty and improving patient outcomes.
A study by Incheon National University researcher finds that job autonomy alone is not enough for public servants to engage in proactive change-oriented behavior. The study identifies factors over which public managers have control, including information, norms, incentives, and human relationships, as levers to encourage change.
Researchers found that positioning stroke patients with large vessel ischemic strokes at 0-degrees resulted in significant improvements in neurological function compared to those with 30-degree head positioning. This approach optimized blood flow through the narrowed artery and improved collateral arteries, leading to better outcomes.
The American Heart Association's PREVENT risk calculator will be evaluated among diverse populations to assess its accuracy and fairness. The research aims to ensure that the tool provides accurate risk predictions for people from various racial, ethnic, and socioeconomic backgrounds.
A recent study published in Hepatology has investigated the connection between platelet function and complications in patients with cirrhosis. The researchers found that decreased platelet activation predicts hepatic decompensation and mortality, highlighting the importance of personalized therapeutic approaches.
Researchers have developed a new gene mapping technique that reveals how genetic alterations in cells lining blood vessels contribute to coronary artery disease. The technique, called Variant-to-Gene-to-Program (V2G2P), identifies biological mechanisms driving CAD risk by linking genetic variants to gene expression and function.
A large study of nearly 200,000 newborns in Sweden and Norway found that COVID-19 vaccination during pregnancy was not associated with any increased risks in newborn infants. In fact, babies born to vaccinated mothers had lower mortality rates and fewer serious complications.
Rates of re-excision after initial breast-conserving surgery remain high across the US, leading to increased healthcare costs and a higher risk of postoperative complications. The study found that younger age and ductal carcinoma in situ are associated with a higher reoperation rate.
New research from Flinders University found that regular exercise and a personalized falls prevention plan based on individual needs can reduce the likelihood of falls. The studies also highlighted the importance of having an individual falls risk assessment and modifying strategies according to specific circumstances, such as dementia.
Researchers created mathematical models to examine aspects of human behavior affecting pandemic trends. They found that risk perception and adherence to preventive measures are crucial in understanding why similar policies resulted in different outcomes.
A new study published in the American Heart Association journal Hypertension found that tirzepatide significantly lowered systolic blood pressure levels in nearly 500 adults with obesity. The results suggest treating obesity with this weight loss medication may be an effective strategy for preventing or treating high blood pressure.
A study from Chalmers University of Technology found that the production and use of ammonia as a marine fuel can lead to eutrophication, acidification, and emissions of potent greenhouse gases. Researchers warn that the pursuit of low-carbon fuels may create new environmental challenges.
Researchers found that Black women who develop high blood pressure before age 45 are twice as likely to suffer a stroke. The study, presented at the American Stroke Association’s International Stroke Conference 2024, highlights the disparity in stroke rates among Black and white women.
People with stroke mimics are at a higher risk of developing post-traumatic stress disorder (PTSD) than those with confirmed strokes. Researchers found that patients with stroke mimics experience significant psychological distress and increased cardiovascular health risks.
A machine learning technique called LASSO was used to analyze blood samples from six countries, identifying seven genes that can predict the risk of developing a secondary respiratory bacterial infection. The findings aim to guide clinicians in making more informed decisions about antibiotic use.
Researchers identified 180,940 people who had suffered a recent stroke and matched them to control groups to evaluate dementia risk after stroke. The study found that the rate of post-stroke dementia was higher than the rate of recurrent stroke over the same time period.
A recent study found that socioeconomic factors, including income, education, and housing quality, significantly impact stroke recovery outcomes. Researchers used data from the U.S. Census blocks to compare outcomes among stroke survivors by socioeconomic disadvantage factors.
Researchers found that SGLT2 inhibitors reduced kidney stone rates by 30% compared to GLP1 agonists and 25% compared to DPP4 inhibitors. The study included data from 716,406 adults with type 2 diabetes who took these medications.
Researchers developed a risk calculator to predict individualized risk of right heart failure after left heart pump surgery, tailoring care to each patient. The STOP-RVF calculator uses machine learning and considers variables such as pre-existing health conditions, medications, and demographic information.
A study of over 1,700 adult patients found that gastric bypass and sleeve surgeries have few short-term complications and are equivalent in terms of risk. The results suggest that patients and doctors can choose between the two procedures without worrying about short-term surgical risks.
A new study found that 50% of youth aged 11-24 with mental health issues exhibit Psychosis Spectrum Symptoms, highlighting the need for early intervention. The study aims to identify predictors of psychosis spectrum disorder and improve mental health outcomes for this population.
A large Finnish study found that external fetal heart rate monitoring without simultaneous maternal pulse recording increases the risk of neonatal encephalopathy and acidemia. The study suggests that combining maternal pulse recording with fetal heart rate monitoring can effectively prevent these complications and improve neonatal outc...
A recent study by University of Missouri researcher Knoo Lee found that school nurses are well-positioned to identify students at-risk for chronic school absenteeism. Students who have many partial-day absences often proactively seek out school nurses as a source of comfort and support, presenting an opportunity for intervention before...
Researchers from Pusan National University found a notable association between smoking and an increased risk of Amyotrophic Lateral Sclerosis (ALS), particularly among female smokers. The study revealed a dose-response relationship, with the risk peaking at moderate to heavy smoking levels.
A study of Medicare patients in 2022 revealed disparities in COVID-19 therapy access based on patient age, race and ethnicity, Medicaid eligibility, and nursing home residence. Higher-risk individuals received COVID-19 therapy less often than those with lower risk factors.
A recent study published in Lancet Microbe suggests that immunocompromised patients are at higher risk for COVID infections, but prolonged infections lasting weeks to months are uncommon. The study found that specific conditions, such as B-cell cancers and autoimmune diseases, increase the risk of prolonged infections.
A Rutgers Health study found that pregnant women exposed to certain flame-retardant chemicals may face an increased risk of preterm birth, especially for baby girls, or higher birth weights. The study linked three specific markers of organophosphate ester exposure to shorter pregnancies and higher risks of preterm birth in female infants.
Persistent withdrawn and somatic symptoms in adolescence increase the risk of suicidal thoughts in mid-adolescence. The study found that these symptoms persist or increase over time to be particularly concerning for suicidal risk.
A international academic consortium has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes. The standout biomarker was N-terminal pro b-type natriuretic peptide (NT-proBNP), which is currently used to monitor heart failure status in patients.
Researchers from Concordia University explore risks of cyberattacks faced by offshore wind farms with VSC-HVDC connections. These attacks could lead to false information, electrical disturbances, and potential transmission of amplified oscillations through the main power grid.
Researchers urge shift towards more sustainable forestry practices and policy to manage global growing flood risk. A probabilistic approach can better understand the effects of deforestation on floods, considering multiple factors like climate change, land use, and logging.
A new study found that heatwaves in Brazil are disproportionately affecting female, elderly, Black, Brown, and low-education individuals, resulting in a staggering 48,075 deaths between 2000 and 2018. The research highlights the need for targeted efforts to reduce mortality rates during future heatwaves.
A large study found that exposure to organophosphate ester flame retardants during pregnancy was associated with preterm birth, especially among female newborns. Higher birth weight was also linked to increased obesity risk. The chemicals are widely used in building materials, furniture, and electronics.
A new compound flooding model predicts that New York City will experience historic and devastating floods every 30 years by the end of this century, a fivefold increase from the present climate. The tool helps city planners prepare and protect against future disasters by providing detailed flood forecasts.
Researchers report a case of a patient with EGFR L858R mutant non-small cell lung cancer (NSCLC) who experienced durable disease improvement after empirical treatment with osimertinib. The 'Lazarus effect' refers to the phenomenon where cancer appears to recur after seeming to be in remission.
Researchers have developed an ultrasound method to predict preterm births by analyzing microstructural changes in a woman's cervix. The study found that this approach is effective at predicting risk during first-time pregnancies and combining data with delivery history for subsequent pregnancies.
A study combines retinal imaging, genetics, and big data to estimate the likelihood of developing eye and systemic diseases. The researchers identified significant associations between retinal layer thickness and increased risk of various diseases, including ocular, neuropsychiatric, cardiac, metabolic, and pulmonary diseases.
Children born between 32-33 weeks and 34-36 weeks have higher long-term risks of neurodevelopmental difficulties, including motor, cognitive, epileptic, hearing, and visual impairments. The study found that these risks should not be underestimated and may help professionals and families better assess risk and follow-up.