Articles tagged with Cancer Treatments
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The American Cancer Society reports a decline in breast cancer death rates among women in affluent areas, shifting the burden to poor women who have lower screening rates. The study highlights disparities in access to prevention and treatment services.
A combination of P16 immunohistochemistry and DNA qPCR has been found to accurately determine oropharyngeal squamous cell carcinoma, a form of head and neck cancer derived from HPV16. This test outperforms existing methods with high sensitivity and specificity, making it a valuable tool for clinicians.
Researchers at the University of Houston have discovered that estradiol, a naturally occurring estrogen hormone, plays a prominent role in regulating body functions in both females and males. The study found that an imbalance of estradiol levels can result in metabolic diseases, including diabetes, obesity, and cardiovascular disease.
Children's National study finds lovastatin improves verbal and nonverbal memory, visual attention, and efficiency in children with neurofibromatosis type 1. The Phase I study suggests a potential therapeutic agent for treating cognitive deficits in NF1 patients.
Research at the University of Texas MD Anderson Cancer Center found that couples counseling significantly improves sexual satisfaction and function for prostate cancer survivors and their partners. Internet-based sexual counseling was shown to be equally effective as traditional sex therapy.
A study found that men over 75 with prostate cancer are being undertreated, while those with a single comorbid condition are being overtreated. The study suggests that individual medical problems impact survival more than age alone.
Researchers have found that treating mice with OCA-1B, a form of oculocutaneous albinism, with nitisinone improves eye and skin pigmentation. The study suggests that nitisinone could potentially ameliorate vision loss in patients with OCA-1B.
A study by Imperial College London found that foam therapy is over four times more cost-effective and quicker than laser treatment for varicose veins. Foam therapy allows patients to resume normal activity sooner and causes less pain.
A University of Kentucky research team, led by Dr. Susanne Arnold, has been awarded a $1.43 million grant to investigate potential environmental factors contributing to the high lung cancer rates in Eastern Kentucky. The study will examine exposure to trace elements and their role in promoting carcinogenesis.
Research suggests that genetic variations in mRNA and microRNA play a critical role in prostate cancer disparities between African-American and white men. The findings could lead to more specialized treatment options for African-American patients.
A recent study found that depression is a significant barrier to preventive health screening among Latina breast cancer survivors. The research revealed that Hispanic breast cancer patients are more depressed than their non-Hispanic counterparts and have lower rates of screening for colorectal and ovarian cancers.
Developed by Cardiff University, the test identifies a wound type based on its gene signature with an initial accuracy rate of 98%. It has the potential to transform service provision and provide the right treatment at the earliest possible opportunity.
Researchers found that minority patients who develop adult leukemia die from it more often than white patients, with blacks having a 45% greater risk of death from ALL and Hispanics having a 46% greater risk. The study used the SEER database to examine statistics from 40,951 patients with acute leukemia over a 10-year period.
Research reveals a strong association between stress and tumor aggressiveness in black and Hispanic breast cancer patients, compared to white patients. The study found that higher levels of psychosocial stress were linked to more aggressive tumors, suggesting potential impact on treatment outcomes.
Foreign-born US women showed higher mammography screening rates over time, increasing from 60.2% in 2000 to 65.5% in 2008, according to a study by Pennsylvania State University researchers. However, disparities persist between immigrant and native-born women, highlighting the need for improved access to healthcare and insurance coverage.
The 24th ECNP Congress presented landmark studies on the burden of mental disorders in Europe, early intervention in schizophrenia, and sex differences in mental disorders. The event emphasized the need for increased funding and better treatment allocation to address these challenges.
Researchers found that Wikipedia's cancer information is accurate and comparable in depth to peer-reviewed sites like PDQ, but less readable due to complex language and hyperlinks. In contrast, PDQ is written in simpler English and offers more patient-friendly explanations.
The study reveals that EGFR plays a crucial role in the development of KRAS-driven pancreatic cancer, blocking its progression without it. Researchers found that mice with EGF receptor deletion had blocked pancreatic cancer development.
A Spanish research establishes factors associated with tiredness in cancer survivors to improve their quality of life and rehabilitation. More than 66% of breast cancer survivors suffer from fatigue following recovery, caused directly by the disease, physical deterioration or treatment received.
A web-based tool called WISE has been developed to help breast cancer survivors manage their symptoms and improve employment outcomes. The tool provides customized information and decision support tools to identify ergonomic workplace problems and implement changes.
A team of researchers has discovered a thermodynamically stable RNA nanoparticle that can serve as a platform for building larger, multifunctional nanoparticles. This breakthrough could lead to new therapeutic applications in treating cancers and viral infections.
Researchers from Lund University have developed a method using ultrasound to improve the quality of transplanted blood stem cells. This improvement could lead to better treatment outcomes and reduced risk of graft-versus-host disease and infections.
A landmark study reveals that mental disorders have become Europe's largest health challenge, affecting 514 million people. The study highlights a significant treatment gap and calls for increased funding and improved care to address the critical challenges facing mental and neurological disorders.
A study found that ALK-rearranged non-small cell lung cancer patients responded significantly better to pemetrexed than those without the genetic mutation. Researchers discovered that ALK positivity was an independent predictor for pemetrexed efficacy, with improved tumor response rates and longer time to progression.
Researchers have defined a specific protein complex that allows cells to remove damaged mitochondria via autophagy, a process crucial for maintaining cellular integrity. This discovery highlights the interaction between Hsp90-Cdc37 and Ulk1, which is essential for efficient mitochondrial clearance.
A decline in hormone therapy use among women aged 50-64 is linked to lower mammogram rates, as doctors may not remind them about upcoming mammograms. The study suggests that the drop in HT use led to a decrease in mammography rates between 2000 and 2005.
A study found a significant increase in use of radioactive iodine after surgery for well-differentiated thyroid cancer, with variation in practice patterns among hospitals. The use was more common in younger patients without comorbidities and those with lower tumor stages.
Recent studies and guidelines suggest that traditional Chinese medicine may be effective in treating seasonal flu, while delayed surgery for hip fractures may not necessarily lead to poor outcomes. Additionally, new guidelines from the USPSTF recommend against bladder cancer screening in asymptomatic adults due to inadequate evidence. ...
Researchers at the University of Toronto have identified a new treatment target for human respiratory syncytial virus (RSV), a common cause of severe lung infections and estimated 10% of colds. The study found that RSV interacts with healthy cells by binding to a molecule called nucleolin, allowing it to decrease or increase infection.
A new study published in Archives of Dermatology found that beta-blocker propranolol was more effective than oral corticosteroids in treating infantile hemangiomas, with higher rates of lesion clearance and fewer adverse effects. Propranolol treatment also led to significant cost savings.
Researchers at National Physical Laboratory develop a model peptide sequence dubbed GeT that transports genetic material into human cells, overcoming poor cell membrane permeability. This approach holds promise for gene therapy in treating defective genes such as cancer.
Researchers investigated potential effects of G-CSF on chromosomes in healthy PBSC donors and found no replication asynchrony or atypical abnormalities. The study concludes that G-CSF mobilization process is safe for healthy stem cell donors, supporting its use in transplants.
Radiofrequency ablation (RFA) successfully eradicates precancerous cells and intestinal metaplasia in patients with dysplastic Barrett's esophagus, with over 90% of patients showing complete clearance after three years. The procedure offers a minimally invasive alternative to surgery, reducing complication rates and mortality.
A new Cochrane systematic review shows that music can reduce anxiety in cancer patients, with positive effects on mood, pain, and quality of life. The results also suggest that music therapy may increase patients' quality of life and have smaller beneficial effects on heart rate and blood pressure.
A new study published in the Journal of Bone and Joint Surgery found that carpal tunnel syndrome patients prefer to share decision-making with their physicians. Patients who had undergone previous surgical procedures, had caregivers, or additional private insurance were more likely to assume an active role in the decision-making process.
A study published in Genes & Development reveals a specific RNA cluster, miR-17~92, plays a key role in the growth of retinoblastoma, a rare form of childhood eye cancer. The researchers found that overexpression of this microRNA cluster helps cells proliferate despite the loss of tumor-suppressing protein Rb.
Most victims of stray bullets are women and individuals outside the typical high-risk age range, highlighting the need for preventive measures. The study found that most victims were unaware of the events leading to the gunfire and often died immediately or shortly after being shot.
A study by Arizona State University researchers aims to understand the connection between gut microbiota and obesity treatment outcomes. The research focuses on two popular obesity treatments: gastric bypass surgery, which has been shown to alter gut microbial populations.
A randomized trial found that standard triple therapy was more effective than newer four-drug regimens in Latin America, justifying population-wide eradication trials to prevent gastric cancers. However, comment authors disagree, citing potential risks and complications associated with mass eradication programmes.
Despite genomics' promise in treating cancer and cardiovascular disease, personalized medicine's complexities limit tailored interventions. The authors advocate for a more holistic approach focusing on the person as a whole, rather than abstract scientific manipulations.
Researchers at St. Jude Children's Research Hospital identified Tsc1 as a key regulator of the immune system, maintaining a balanced immune response by inhibiting effector T cells and naïve T cells. Loss of Tsc1 leads to premature activation and depletion of immune cells, compromising bacterial infection resistance.
A Phase III trial found that amrubicin significantly improved tumor shrinkage, symptom control, and progression-free survival compared to topotecan in lung cancer patients. Patients treated with amrubicin also reported better quality of life and fewer adverse events.
Researchers found that one-to-one therapy sessions to teach pelvic floor exercises were no more effective in managing urinary incontinence after prostate surgery than standard care. In fact, the intervention resulted in higher costs per patient without a significant impact on quality of life.
Researchers at John Theurer Cancer Center found that patients with more partner support experience less distress after stem cell transplants. The study suggests that social support plays a crucial role in improving patient outcomes and quality of life.
A new psychotherapy intervention, dignity therapy, significantly improves quality of life and enhances the dignity of patients at the end of life, while helping their families. The study found that dignity therapy reduces distress and enriches the end-of-life experience compared to standard palliative care and client-centred care.
Inhibiting heat shock transcription factor 1 (HSF1) prevents liver cancer in mice by reducing access to glucose and lipids, which are critical for tumor growth. This finding supports the idea that altering metabolism can be an effective cancer treatment.
A new study reveals that ALK rearrangement affects nearly 10% of lung cancer patients, while MET amplification occurs in another 4.1%. This could lead to targeted therapy options like crizotinib for these patients.
Researchers mapped out the order of DNA changes in advanced skin and ovarian tumors using a statistical approach, finding that key gene TP53 mutations occurred earlier than previously believed. This discovery could help identify personalized therapies for cancer patients by targeting early mutations.
A recent Nevada study found that over two-thirds of respondents approved using therapeutic cloning and stem cells to cure cancer or treat heart attacks. For treatment of less-serious conditions, approval rates were lower but still significant. The study suggests a strong public support for stem cell research in the US.
New tools and methods enable targeted gene delivery to cells in the central nervous system, offering hope for new treatments. Novel strategies include using stem cells and siRNAs to silence genes involved in neurological diseases.
Researchers at Buck Institute discover lithium profoundly prevents brain damage associated with Parkinson's disease in a mouse model. The study's findings suggest that lithium could be an effective treatment for PD patients at subclinical levels, avoiding side effects.
A holistic approach to treating cancer pain that addresses psychological, social, and spiritual needs can enhance treatment outcomes and ease suffering. Research suggests integrating palliative care from diagnosis can improve quality of life, reduce depression, and increase survival time for lung cancer patients.
The UH Cancer Center has received a significant gift to accelerate mesothelioma research, with scientists working on developing new therapies to prevent and treat the disease. Recent breakthroughs have shed light on potential causes, including exposure to erionite particles found in airborne asbestos.
A study published in Archives of Surgery found that most hospitals follow established practice guidelines for surgical treatment of cancer patients with Medicare. However, disparities in care exist, with patients receiving the right care at the right time not always guaranteed.
A multicenter pilot study found etanercept successfully weaned patients from steroid therapy, with no significant increase in adverse event rates. Larger studies are needed to investigate the safety and efficacy of etanercept for dermatomyositis treatment.
Van Andel Research Institute scientists found a protein that predicts the spread of nasopharyngeal carcinoma, a deadly head and neck cancer common in southern China and Southeast Asia. Higher levels of serglycin correlate with poor prognosis and increased metastasis, suggesting it as a therapeutic target to stop disease progression.
A low-carbohydrate, high-protein diet has been shown to slow the growth of tumors and reduce the risk of cancer in mice. The study found that restricting carbohydrate intake can limit blood glucose and insulin, promoting tumor growth. A low-carb diet also boosted the immune system's ability to kill cancer cells and prevented obesity.
Researchers used time-lapse video microscopic technology to observe early stages of ovarian cancer metastasis. The study identified the force-dependent processes necessary for tumor cells to attach to and proliferate on organs in the peritoneum.
Proactive telephone counseling helps increase long-term smoking cessation, with a positive effect on both point prevalence and prolonged abstinence. The study suggests that active recruitment methods do not significantly impact quit rates, contrary to previous assumptions.
Researchers at University of Western Ontario discovered how biochemical pathways can be rewired in cancer cells to resist apoptosis, a key process in normal cell turnover. This 'rewiring' allows cancer cells to ignore death signals and potentially evade therapy.