Articles tagged with Cancer Treatments
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A clinical trial at Michigan State University is testing the effectiveness of acetazolamide in reducing vision loss in patients with idiopathic intracranial hypertension (IIH). The study aims to establish evidence-based treatment strategies and follow patients for up to four years to observe long-term treatment outcomes.
A recent study by Fred Hutchinson Cancer Center found that bankruptcy rates among cancer patients rise fourfold within five years of diagnosis. The risk is highest for lung, thyroid and leukemia/lymphoma cancer patients, who face significant financial stress due to income loss and treatment costs.
Researchers identified phytochemicals in mushrooms that block aromatase enzyme activity, potentially reducing estrogen levels and killing hormone-dependent breast cancers. Early-stage studies show promise in preventing breast cancer recurrence and treating lung cancer.
A new study by St. Michael's Hospital reveals that female prisoners who did not participate in a drug treatment program after their release were 10 times more likely to return to prison within one year. The study highlights the importance of post-release treatment programs for prisoners with substance abuse problems.
A recent Korean survey found that most cancer patients, family members, oncologists, and the general public are receptive to ending futile life-sustaining treatments for terminally ill patients. This positive attitude towards withdrawing such treatments is attributed to patient autonomy and hastening the dying process.
Advancements in telemedicine, medical robots, biomarkers, neural engineering, tissue engineering, and regenerative medicine are transforming patient care. Five key areas of convergence will drive healthcare's future.
A study of 1032 patients with early RA found that initial treatment with adalimumab plus methotrexate provided high levels of disease control, with 44% achieving sustained low disease activity. Patients who continued treatment maintained good clinical and radiographic responses, even after withdrawing treatment.
A recent study found that men who walk briskly after diagnosis have a 57% lower rate of progression of disease than those who walk at an easy pace. Brisk walking can delay or even prevent progression of prostate cancer.
Research suggests that doctors should tailor treatment to specific qualities of second tumor, regardless of whether it's old or new. Studies found that 89% of recurring tumors differed in at least one characteristic compared to the original tumor.
Researchers have discovered a new mechanism of action for Herceptin, revealing its ability to stimulate interferons and activate lymphocytes. Combining Herceptin with lymphocyte-stimulating therapies greatly increases efficacy in animals, paving the way for targeted therapies.
A study published in Archives of Otolaryngology–Head and Neck Surgery found that propranolol therapy improved the size and quality of head and neck hemangiomas in children. The medication was effective in reducing tumor size, flattening lesions, and changing their color, even in cases where previous treatments were unsuccessful.
A new study from UCSD School of Medicine reveals the plasticity of some gene expression programs, allowing for alternative induced gene expression. This plasticity may contribute to cancer cell growth and normal differentiation, with implications for hormone therapy.
A new study examines the trend of radical nephrectomy rates in patients with clinically localized renal masses and finds that despite guidelines recommending kidney preservation, laparoscopic procedures have become more prevalent than expected. This shift may lead to increased morbidity and mortality due to chronic renal insufficiency.
Researchers from Fox Chase Cancer Center investigated the effectiveness of active surveillance in patients with small renal masses. They found that in select patients, active surveillance may be a viable option when surgery is risky due to poor health or advanced age.
Patients with small kidney tumors are more likely to be offered partial nephrectomy based on surgeon's case volume and type of practice. Fellowship-trained surgeons in academic centers were 70-80% more likely to follow guidelines, while those in private practice saw fewer patients offered radical nephrectomy.
Researchers from NewYork-Presbyterian/Weill Cornell presented studies on the effectiveness of robotic-assisted laparoscopic radical prostatectomy, finding lower perioperative morbidity and improved oncologic outcomes compared to open and laparoscopic approaches. Additionally, they investigated the feasibility and safety of robot-assist...
The healthcare system will double the size of its cancer treatment facility in a new hospital, allowing more patients to receive care from more physicians. The remaining funds will support critical cancer research, bridging the gap between lab discoveries and patient therapies.
Researchers found that a small RNA pathway is required to establish DNA methylation, a process that silences genes. This discovery may lead to new therapies for cancer and other diseases by reactivating silenced tumor-suppressor genes.
A new study by the NYU Cancer Institute reveals that novel mutations in the Notch signaling pathway lead to the development of chronic myelomonocytic leukemia, a type of blood cancer. The study suggests potential targets for future therapies.
A new study published in Music and Medicine found that palliative care patients experience enhanced pain relief, comfort, relaxation, and mood through a unique music therapy project. The project, led by Concordia University's Sandi Curtis, combined students with professional musicians to provide individualized music therapy sessions.
A study found that CTPA screening led to a 81% increase in PE diagnoses, but only a 3% decrease in mortality rates. The authors suggest overdiagnosis due to the detection of clinically insignificant small emboli.
A study from Beth Israel Deaconess Medical Center found that nearly 3% of Americans using mind-body therapies were referred by a healthcare provider, suggesting a shift towards mainstream acceptance. These patients were sicker and used the healthcare system more than those who self-referenced for MBT.
A new UK-wide centre of excellence will train PhD researchers to use next-generation laser-operated accelerator devices for improved cancer treatment and enhanced homeland security. The programme combines physics with biology and medicine, offering students opportunities to work with industry and health authorities.
Researchers identified a regulatory protein that inhibits cancer cell spread by removing an invasive enzyme. This enzyme degrades surrounding tissues, facilitating cancer metastasis. The discovery may lead to more targeted therapies with specific inhibitory functions.
A new study found that radiologists using MRI can correctly identify the primary site of cancer in 79% of cases, even when biopsy results are inconclusive. This improves patient outcomes by providing more accurate treatment options.
The landmark event brought together pediatric urologists worldwide to share ideas and advance research. Key findings highlight the growing importance of pediatric urology as a global specialty.
A study of 435 women who underwent treatment for precancerous cervical lesions found that a three-cytological-smears post-treatment surveillance strategy is effective in identifying women at long-term risk of cervical cancer. By adding high-risk human papillomavirus (hrHPV) testing, the need for subsequent screens can be reduced.
A healthcare alliance has launched a training program in Mexico to address the significant rates of tobacco usage in Latin America. The program aims to enhance access to proven treatment methods and promote effective tobacco control policies across the region.
Global Bridges, a healthcare alliance for tobacco dependence treatment, is launching training in the Eastern Mediterranean Region. The first training will engage 15 health care professionals from Jordan and focus on culturally appropriate tobacco dependence treatment.
Scripps Research and Moffitt Cancer Center collaborate on a $2.1 million grant to understand the origins of prostate cancer and develop novel treatments. The study aims to define how B cells control the spread of hormone-refractory cancer, potentially leading to effective treatments.
Multipolar electrocoagulation ablation therapy in combination with acid suppression is a safe and effective method to ablate nondysplastic Barrett's esophagus over the long term, according to a new study. No adenocarcinoma or high-grade dysplasia developed in any of the study patients.
Researchers found three distinct gut types, each associated with unique microbial genetic markers. These markers may help diagnose diseases like colo-rectal cancer and predict treatment outcomes.
University of Cincinnati researchers have successfully produced large RNA nanoparticles using a bipartite approach, overcoming challenges in industry-scale production. The nanoparticles, containing small interfering RNA, show a half-life of between five and 10 hours in animal models, are non-toxic and produce no immune response.
University of Iowa researchers identify TRAF6 as essential for LMP1 functions, which can be targeted to develop new therapies for B cell lymphomas and autoimmune diseases. The discovery may lead to the development of novel treatments that mimic CD40 activation while avoiding disruptions in normal immune function.
A phase 3 trial found subcutaneous administration of bortezomib to be as effective as intravenous delivery, but with a better safety profile and lower rates of peripheral neuropathy. Subcutaneous injection could provide an easy home-based treatment option at reduced cost.
A group of radiologists and biochemists have developed a new approach to improve the accuracy and reliability of medical imaging. By creating standardized benchmarks and calibration objects, they aim to provide hard numbers that can be used to justify treatments and accelerate cancer treatment approvals.
A large-scale study of 769 men with low-grade prostate cancer found that closely monitoring the disease without immediate treatment does not raise the risk of death. Men who undergo active surveillance are less likely to need subsequent surgery or radiation if their cancer progression is carefully monitored.
A new study suggests that less invasive lymph-node biopsy can accurately diagnose lymph node status in patients with early stage endometrial cancer, reducing the risk of surgical complications. The procedure has been shown to be safe and effective, with a negative predictive value of 97% and sensitivity of 84%.
A new study published by NCI and CDC found a significant shift in the distribution of cancers in the HIV/AIDS population. Cases of AIDS-defining cancers decreased threefold between 1991-95 and 2001-05, while cases of other cancers increased tripled during the same period.
Hebrew University researchers have discovered a new mechanism by which tumor cells become invasive, involving a program of genes that confer invasive properties on epithelial cells. The study suggests that p53, a key tumor suppressor, may play a critical role in cancer prevention through its inhibition of cell invasion.
Researchers at University of Michigan have developed a novel gene therapy, NP2, that shows promise in providing substantial pain relief for patients with unrelenting cancer-induced pain. The study demonstrates the safety and efficacy of NP2 in reducing pain by up to 80% over four weeks.
A survey of US primary care physicians found that making treatment recommendations changes the way physicians think about medical decisions. In scenarios involving colon cancer and avian influenza, physicians chose different treatments for themselves versus those they recommended to patients.
The number of AIDS-defining cancers decreased, while non-AIDS-defining cancers increased significantly between 1991-2005. Lung cancer emerged as the most common malignancy in people with HIV but not AIDS.
A new study published in the Journal of the American Heart Association found that video game treatment can significantly improve upper-arm motor function in stroke survivors. Virtual reality games showed promise as a promising and potentially useful alternative to traditional physiotherapy.
Research discovers TBL1 protein plays critical role in fatty liver development; higher triglyceride levels associated with lower TBL1 production. This finding may enable early identification of high-risk individuals and targeted dietary interventions.
An observational study found that women with poor physical health scores had a 27% increased risk of cancer recurrence or new breast cancer. Physical health also impacted survival, with a 65% greater risk of death among those with poorer health scores.
Researchers investigated the association between bleeding and mortality in patients on dual antiplatelet therapy (DAPT) versus aspirin alone. The study shows patients with moderate or severe bleeding had a higher incidence of all-cause, cardiovascular and cancer mortality.
Researchers at Fox Chase Cancer Center have found a direct correlation between the expression of a key tumor suppressor protein and premature aging in mice. The study suggests that blocking cell proliferation induced by the p16 protein leads to features of premature aging, not just molecular damage.
A recent study suggests that estrogen-only hormone therapy may decrease the risk of breast cancer in women who have had a hysterectomy. However, experts caution against long-term use due to unknown consequences and conflicting evidence from previous studies.
Research reveals that people with AIDS have a significantly higher risk of developing stomach and esophageal malignancies, including a 6.9-fold increased incidence of stomach cancer and a 2.7-fold increased risk of esophageal cancer compared to the general population.
Researchers found significantly higher rates of HPV antibodies in people with lung cancer compared to those without the disease. High-risk types of HPV were particularly prevalent, suggesting a potential link between HPV infection and lung cancer development.
A recent study published by the American Association for Cancer Research found that nicotine at doses similar to those found in most nicotine replacement therapies did not increase lung cancer tumor incidence, frequency or size. The researchers concluded that nicotine replacement therapy is probably a safe option.
A recent study presents a promising serum test that can identify lung cancer in people who have never smoked. The test uses a panel of biomarkers to analyze blood samples and has shown high sensitivity and specificity in distinguishing lung cancer from non-cancerous conditions.
Researchers have developed a novel biomarker test that can detect proteins secreted from tumors caused by asbestos exposure with high accuracy. The test, which uses aptamer proteomics platform, showed an 80% sensitivity rate in detecting stage 1 or 2 malignant pleural mesothelioma, a type of aggressive and often fatal lung cancer.
Researchers found that individuals with metabolic syndrome are at higher risk for developing liver cancers, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma. The study, presented at the AACR 102nd Annual Meeting, highlights the importance of metabolic syndrome in increasing liver cancer incidence.
Researchers have identified an oncogenic gene fusion of KRAS in a metastatic prostate cancer cell line, shedding light on the genetic characteristics of this disease. This finding may enable better prognostic information to separate slow-growing tumors from aggressive ones, ultimately improving treatment strategies.
A study found that improved quality of life and reduced stress response were associated with changes in telomere length in cancer patients. Psychological counseling had a potential impact on modulating telomere length, but the findings require further exploration.
The US saw a decline in cancer death rates between 2003 and 2007, with the overall rate of cancer deaths falling by an average of slightly less than 1 percent per year. Despite this encouraging trend, experts caution that more efforts are needed to prevent and treat cancer effectively.
New modeling studies support EU policy efforts to address HCV-related morbidity and mortality. With ambitious policies, HCV-related mortality could decrease by up to 12% over nine years, corresponding to a relative impact of 117% compared to current practice.
A new interventional radiology treatment blocks blood supply to men's enlarged prostate glands, showing comparable clinical results to transurethral resection of the prostate. The minimally invasive treatment has none of the risks associated with TURP, such as sexual dysfunction and urinary incontinence.