Articles tagged with Cancer Treatments
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Incorporating ovarian cancer subtypes into screening models reduces predicted mortality rates. However, catching slower-growing cancers won't significantly impact deaths compared to more lethal tumors.
A study published in Neurology found that nearly 40% of brain tumor patients use alternative therapies, including homeopathic remedies and vitamin supplements. Younger people, women, and those with more education were more likely to use these treatments, which they often sought to add benefits to conventional care.
A study found that combining epigenetic therapy and molecular targeted therapy can improve outcomes for patients with elevated E-cadherin levels in advanced lung cancer. The treatment achieved significantly improved overall survival rates compared to erlotinib alone.
A La Jolla Institute team has validated a computer model's ability to predict key information on nasal insulin treatment regimens in type 1 diabetes. The platform accurately predicted biomarker onset and therapeutic outcome, confirming its potential as a valuable research tool.
A groundbreaking clinical trial is examining the safety of hypothermia in elderly stroke patients, aiming to improve outcomes and prevent neurological damage. The study, led by top researchers, will enroll 400 patients at multiple US and European sites and investigate the effectiveness of therapeutic brain cooling.
Researchers at Mayo Clinic found that JAK inhibitors CYT387 and TG101348 effectively reduce spleen size and alleviate constitutional symptoms in myelofibrosis patients. These targeted treatments have shown significant clinical benefits, including improved anemia rates and reduced white blood cell counts.
Researchers found that apixaban was more effective than enoxaparin in preventing major venous thromboembolism without increasing bleeding risk. This innovative treatment has improved methods for patients undergoing hip or knee replacement surgery, and may also be beneficial for cancer patients with VTE.
A study found that decreased physician reimbursement for hormone therapy reduced its use in low-risk prostate cancer cases by 40%. However, AST usage remained unchanged in patients with metastatic disease. The decrease is attributed to the real effect of reimbursement change.
A study presented at the Radiological Society of North America annual meeting found that diagnosis uncertainty can be as stressful as knowing a serious illness, with breast biopsy patients reporting significantly higher anxiety levels. Healthcare providers can alleviate patient stress by improving communication and shaping expectations.
A new study finds that a less invasive method for determining lung cancer stage improves detection of metastases and reduces surgical procedures. The method, which combines endosonography and ultrasound, was more effective than traditional surgical staging in identifying patients who needed further treatment.
A study published in Cancer Research reveals that microRNA-375 plays a crucial role in breast cancer cells, leading to increased estrogen receptor alpha levels. Blocking this microRNA effectively slows down cancer cell growth, offering potential new strategies for treatment.
During pregnancy, pregnant women can experience significant changes in their oral health, including gingivitis, pregnancy tumors, and mild to severe gingival enlargement. Regular dental check-ups and proper oral hygiene can help alleviate gum inflammation and prevent worsening of conditions.
A Johns Hopkins study found that delayed HIV treatment adds tens of thousands of dollars in care costs and reduces survival rates. Patients who wait too long to receive treatment require more expensive antiretroviral therapy, antibiotics, and hospitalizations.
High-throughput DNA sequencing of gut bacteria confirmed that antibiotic treatment disrupts bacterial patterns, which precedes VRE colonization and bloodstream invasion. Monitoring fecal bacteria content could identify patients at high risk of life-threatening infections.
The 2010 Golf Atlanta charity golf tournament raised $105,000 to support investigations into pancreatic cancer at The Translational Genomics Research Institute. The event drew 124 players and included a high-end auction with donations supporting TGen's life-changing research.
Geraldine Dawson, Ph.D., has been recognized as a "Rock Star of Science" for her extensive contributions to autism research and advocacy. Her work aims to discover the causes and effective treatments for autism, with a focus on improving lives for individuals with autism and their families.
A study found that targeting HDMX overcomes p53 suppression and resistance to selective HDM2 inhibition, restoring tumor suppressor pathway in cancers expressing both proteins. The research enables new therapeutic strategies for human cancer, including those resistant to current treatments.
A new indicator, TLR9 receptor, has been found to mark rapidly progressing idiopathic pulmonary fibrosis, potentially leading to new treatments. Researchers identified the receptor in patients' lungs and showed its role in fibrotic tissue growth using human cells and mice.
A study published in JNCI Journal of the National Cancer Institute found that men taking androgen deprivation therapy for prostate cancer have a 30-40% increased risk of colorectal cancer. The longer treatment duration, the greater the risk.
A new study shows that bihemispheric transcranial direct current stimulation (tDCS) coupled with physical and occupational therapy significantly improves motor function in stroke patients. The therapy rebalances brain activity on both sides of the brain, enhancing recovery.
Despite strong evidence of its effectiveness, only one-third of eligible young women complete the recommended three-dose regimen for the human papillomavirus (HPV) vaccine. Persistent infection with certain HPV types may lead to cervical cancer.
A study found that physical activity reduces the risk of endometrial cancer, even among overweight women. Women exercising for 150 minutes per week had a 34% lower risk compared to inactive counterparts.
A study analyzing European Prospective Investigation into Cancer and Nutrition data found that current hormone therapy use increases the risk of ovarian cancer by 29%. The risk did not differ by type or duration of hormone therapy, suggesting a potential long-term hazard.
Neonatal mice separated from their mothers for a prolonged period developed mammary tumors twice as fast as those with short or no maternal separation. Estrogen receptor alpha levels were also significantly higher in mice exposed to prolonged separation, increasing breast cancer risk.
A large prospective cohort study found that smoking significantly increased the risk of breast cancer progression and overall death among multiethnic women. Current or past smokers had a 39% higher rate of dying from breast cancer.
A study by LSU Health Sciences Center researchers found that Docosahexaenoic acid (DHA), a fish oil component, can protect brain tissue and promote recovery in acute ischemic stroke even when treatment is delayed. DHA treatment reduced swelling and facilitated neurobehavioral recovery.
A study found that high soy isoflavone intake was associated with a 30% decreased risk of invasive breast tumors and a 60% decreased risk of grade 1 tumors. In premenopausal women, the highest isoflavone intake reduced the risk of stage I disease, tumor size, and stage 2 breast cancer by significant margins.
Researchers found distinct DNA alterations in lung tumors from smokers and never-smokers, suggesting two possible disease pathways. The study suggests that lung cancers in never-smokers require further investigation to improve detection and treatment strategies.
Weill Cornell Medical College researchers discovered secondary mutations in prostate cancer cells that make them lethal. This finding could lead to better tests and individualized therapy for deadly prostate cancers.
Researchers found that narciclasine, a natural compound in daffodil bulbs, markedly reduces cancer cell proliferation and migration. The study suggests that narciclasine selectively inhibits the growth of very aggressive cancer cells while avoiding adverse effects on normal cells.
Recent studies have identified 20 genes associated with multiple sclerosis susceptibility, paving the way for more accurate understanding of the disease. New therapies targeting neuroinflammation and regenerative stem cells hold promise for controlling the disease, mirroring progress made in AIDS treatment.
The VCU Massey Cancer Center has received a $2.4 million grant from the Virginia Tobacco Commission to expand its community outreach programs and grow its clinical research capabilities. This funding will support the extension of cancer prevention and control initiatives into tobacco counties in Southside and Southwest Virginia.
Researchers found a microRNA binding variant linked to improved survival rates in early-stage colorectal cancer patients, particularly those with KRAS mutations. The variant, previously associated with poor outcomes, was unexpectedly beneficial due to an unidentified compensatory pathway controlling the gene.
Demetrius H. Bagley, M.D., a renowned urologist and researcher at Thomas Jefferson University, has received the Karl Storz Lifetime Achievement Award in Endourology for his pioneering work in ureteroscopic management of upper tract pathology.
Groopman's research identified the link between environmental carcinogens and liver cancer, providing new prospects for prevention in high-risk populations worldwide. His work elucidated the role of aflatoxins in inducing hepatocellular carcinoma, a major cause of mortality in developing countries.
Researchers at IRIC discovered a protein complex, EJC, that controls the production of MAPK protein, which acts directly on cells. Targeting this complex could prevent abnormal signal transmission that triggers several cancers.
A recent study published in European Urology found that nearly 87% of prostate cancer patients who underwent robot-assisted radical prostatectomy had no recurrence after five years. The study, led by Dr. Mani Menon, suggests that robotic-assisted surgery is an effective treatment for localized prostate cancer.
Researchers have discovered a crucial mechanism for regulating gene expression, where noncoding RNAs interact with DNA to silence specific genes. This breakthrough sheds light on the complex interactions between epigenetic regulation and noncoding RNA molecules.
This special issue of Perspectives on Psychological Science investigates the potential of genetics research, personalized medicine, and behavioral intervention to improve patient care. The articles examine the intersection of behavior and genetics, with a focus on tailoring treatments to individual genetic characteristics.
The DFG is establishing four new Research Units to explore topics such as sacrality in pre-modern era, placebo and nocebo effects, and developing new methods for surgical interventions on the skull. These units aim to enable researchers to devote themselves to current issues and develop new approaches.
The AACR will honor two leading breast cancer researchers, Klaus Pantel and Alan Ashworth, for their groundbreaking work on detection and treatment of breast cancer. Pantel will receive the Outstanding Investigator Award for his pioneering research on minimal residual disease, while Ashworth will deliver the Distinguished Lectureship f...
Researchers found that androgen deprivation therapy is associated with structural decay of cortical and trabecular bone in men with prostate cancer. The study used virtual bone biopsies to assess bone microarchitecture and found a link between testosterone deficiency and increased fracture risk.
A new study published in Archives of General Psychiatry found family-based treatment to be the most effective approach for treating anorexia nervosa. More than 50% of patients who received this type of treatment were in full remission after a year, compared to 23% of those who received individual therapy.
A retrospective cohort study of 983 women found that non-Hispanic black and Hispanic women experienced significantly longer diagnostic delays than white women, regardless of insurance status. Diagnostic delay times ranged from 11.9 to 70.8 days, with uninsured black women facing the longest waits.
Researchers found that Puerto Rican women with triple-negative breast cancer had a higher risk of death from breast cancer, even after adjusting for age and cancer stage. Women under 50 years old with regional/distant disease were also more likely to die from their breast cancer.
Data from a national survey reveals that nonwhite female cancer survivors receive significantly less social support than their white counterparts. The study suggests that this disparity may be linked to differences in engagement with moderate-intensity physical activity, which was found to be similar across racial groups.
A recent study found that patients without private health insurance had significantly poorer cancer survival rates compared to those with insurance. The study, which analyzed data from 178,891 patients, also found that African-American patients were twice as likely to die within four years of diagnosis.
African-American women with breast cancer experience longer delays in treatment compared to white women, even when controlling for socioeconomic status and insurance type. The study found that the time to treatment lags behind recommended guidelines by an average of 12 days.
Vitamin D deficiency is associated with a higher likelihood of aggressive breast cancer in African-American women. Vitamin D levels were found to be 29.8 ng/ml in white women and 19.3 ng/ml in African-American women.
Researchers found a significant correlation between low socioeconomic status and late-stage, non-localized colorectal cancer diagnoses. Participants from less deprived neighborhoods had a lower incidence rate of 16.2%, while those from more disadvantaged areas had a higher incidence rate of 19.8%.
Genetic tests are increasingly being offered directly to consumers in Puerto Rico, leading to higher awareness levels compared to previous U.S. population-based studies. However, the actual use of these tests is lower than expected, affecting specific groups such as smokers.
A group-based, holistic mind-body intervention was found to be equally effective in treating persistent fatigue and improving quality of life for breast cancer survivors across different racial groups. The program combined relaxation techniques, nutrition optimization, physical activity, and cognitive behavioral therapy.
A $1.5M NIH grant supports Manu Platt's project to develop models for identifying children at risk of stroke due to sickle cell disease. The goal is to create a mathematical model predicting stroke risk and allow for earlier intervention, improving treatment options.
Researchers at Boston University School of Medicine have discovered a key protein factor, Ets1, involved in the progression of lung cancer. The study aims to identify new therapeutic targets to block tumor growth and metastasis, offering hope for improved patient outcomes.
Historians uncover previously unseen correspondence between Francis Crick and Maurice Wilkins, revealing a tangled web of ambition and institutional politics. The letters provide fresh insights into the personalities of the discoverers and their roles in the discovery of DNA's double helix structure.
A new blood test called AccuPSA can detect rising prostate specific antigen levels after radical prostatectomy, allowing for earlier detection of cancer recurrence. This test has the potential to eliminate unnecessary treatments and improve health care costs by enabling earlier treatment with potentially better outcomes.
Seth Field, a UC San Diego researcher, has been awarded $3.86 million to study GOLPH3's role in breast cancer. His project aims to understand the mechanism by which GOLPH3 contributes to cancer and develop new therapy targets.
Targeting c-Met shows promise in treating HCC patients with positive tumors, according to a study. c-Met is overexpressed in metastatic liver cancer cells, driving growth and invasion.
The Program for Fertility Preservation at Women & Infants Hospital offers fertility preservation options to young cancer survivors, including freezing ovarian tissue and eggs for future use. This experimental program aims to provide hope and promise of fertility to those affected by childhood cancer.
Researchers identified 79 microRNAs linked to bladder cancer, showing promise for early detection through existing laboratory tests. The new method measures microRNA presence or absence in bodily fluids with high accuracy, comparable to current gold standard testing.