A study found that non-invasive ventilation used as a weaning technique can shorten intubation time and reduce the risk of post-extubation acute respiratory failure. Additionally, NIV used as a rescue therapy significantly reduces the risk of reintubation and death in patients with chronic hypercapnic respiratory failure.
SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateJun 10, 2011
A clinical trial at Michigan State University is testing the effectiveness of acetazolamide in reducing vision loss in patients with idiopathic intracranial hypertension (IIH). The study aims to establish evidence-based treatment strategies and follow patients for up to four years to observe long-term treatment outcomes.
A USC study shows that small, daily changes to a healthy lifestyle can significantly improve quality of life for seniors. The trial involved over 200 participants aged 60+, who made sustainable changes such as visiting museums or taking public transportation, resulting in lower rates of depression and improved overall well-being.
SourceUniversity of Southern California·JournalJournal of Epidemiology and Community Health·DateJun 7, 2011
A new glioblastoma vaccine has demonstrated safety and effectiveness in a Phase 2 clinical trial, extending median survival to 11 months for patients with recurrent brain cancer. The vaccine was found to induce an immune response against tumor-specific targets, suggesting potential for improved treatment outcomes.
SourceUniversity of California - San Francisco·DateJun 4, 2011
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
The COIN trial found that standard chemotherapy with cetuximab does not improve progression-free survival or overall survival in patients with advanced colorectal cancer. However, taking treatment breaks without compromising survival improves quality of life for most patients.
SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateJun 3, 2011
A phase II clinical trial found PCI-32765 to be highly active in treating chronic lymphocytic leukemia (CLL), achieving complete remission in one patient and partial remissions in 62% of previously untreated patients, with tolerable side effects.
SourceOhio State University Wexner Medical Center·DateJun 3, 2011
Researchers at VCU Massey Cancer Center have successfully completed a Phase I clinical trial evaluating the combination of Bortezomib and Alvocidib in patients with relapsed or refractory blood cancers. The therapy showed encouraging results, with 44% of patients responding to the treatment.
SourceVirginia Commonwealth University·JournalClinical Cancer Research·DateJun 2, 2011
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
The first controlled clinical trial for Juvenile Batten disease begins this summer, enrolling 30 patients who will take mycophenolate or a placebo for eight weeks. Researchers hope to slow or halt disease progression with immunosuppression.
SourceUniversity of Rochester Medical Center·DateMay 31, 2011
A phase 3 trial of a novel gene therapy failed to reduce amputations or deaths in patients with critical limb ischemia. The study highlights the need for effective treatments for this condition, which affects millions worldwide and results in significant healthcare costs.
A new treatment combines minimally invasive surgery and t-PA to dissolve blood clots in brain tissue. The treatment showed significant improvement in clot size reduction and patient recovery compared to supportive care.
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A National Institutes of Health grant has been awarded to Nationwide Children's Hospital to develop a gene therapy for MPS IIIB, a fatal lysosomal storage disease. The therapy aims to deliver needed genes directly to the central nervous system by bypassing the blood-brain barrier.
A sub-analysis of the EMPHASIS-HF trial found eplerenone significantly reduced new onset atrial fibrillation and flutter in patients with class 2 heart failure. The benefits of eplerenone were similar in patients with and without atrial fibrillation at baseline.
SourceEuropean Society of Cardiology·JournalNew England Journal of Medicine·DateMay 22, 2011
Patients with mild to moderate dyssynchrony and preserved contractile function benefit most from CRT-D, according to the latest MADIT-CRT trial analysis. The study found that improvements in synchrony and contractile function are associated with reduced death and heart failure events.
Recent meta-analyses show telemedical monitoring can improve overall survival by 17-47% in CHF patients. Two trials presented at the Heart Failure Congress 2011 found benefits in specific subgroups, including those with prior decompensation and no depression.
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
The RTOG 0525 Phase III Trial Comparing Conventional Adjuvant Temozolomide with Dose-Intensive Temozolomide in Patients with Newly Diagnosed Glioblastoma found no significant improvement in overall patient survival or disease progression for patients who received dose-intensive temozolomide plus radiotherapy. However, the trial demonst...
A cluster randomized trial found that lifestyle interventions, including physical activity and dietary counselling, reduced the risk of large for gestational age newborns by 44% in pregnant women at high risk. However, the study did not show a significant reduction in the risk of gestational diabetes.
Rapid treatment with medication and surgical procedures is crucial for stroke patients, reducing recurrence risk by 20%. Rehabilitation care has improved significantly over the past two decades, but evidence gaps remain, particularly in addressing mobility and speech impairments.
A study by Asita De Silva and colleagues found that low-dose adrenaline given before antivenom treatment significantly reduces acute severe reactions in snakebite patients. This finding highlights the importance of improving antivenom quality in countries where snakebites are common.
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
A Cochrane Systematic Review of randomized controlled clinical trials found no protective effect against non-melanoma skin cancer and prostate cancer. Researchers also noted potential toxic effects from long-term selenium intake.
SourceWiley·JournalCochrane Database of Systematic Reviews·DateMay 10, 2011
A study found that less than half of patients with stable coronary heart disease receive optimal medical therapy before percutaneous coronary intervention (PCI) and almost one-third do not receive it at discharge. The use of PCI did not show significant benefits over optimal medical therapy in patients with stable coronary artery disease.
A systematic review found that PDE4 inhibitors, such as roflumilast and cilomilast, improve lung function and reduce the likelihood of a flareup in patients with COPD. However, these treatments do not increase general quality of life. Further research is needed to assess longer-term effects
SourceWiley·JournalCochrane Database of Systematic Reviews·DateMay 10, 2011
A randomized trial found women are at more than double the short-term risk of stroke following carotid stenting compared to traditional surgery. This study suggests that sex should be considered when choosing treatment options for carotid disease, as men show little difference in stroke risk between procedures.
SourceThe Lancet_DELETED·JournalThe Lancet Neurology·DateMay 8, 2011
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A potential celiac disease vaccine, Nexvax2, has demonstrated safety and efficacy in a Phase I clinical trial, with the goal of treating the autoimmune disease by desensitizing patients to specific gluten peptides. The vaccine is expected to enter Phase II trials within the next year.
Researchers found GM-CSF crucial for MS disease progression, neutralizing it could reverse inflammation. A clinical trial is set to launch this year to test GM-CSF neutralization in patients.
SourceUniversity of Zurich·JournalNature Immunology·DateApr 24, 2011
A study of over 70,000 type 2 diabetes patients aged 60 and above found that very low blood sugar levels were associated with a small but significant increased risk of death, while those with intermediate levels of control had the best overall outcomes. Researchers emphasized the need for further research to understand the clinical imp...
SourceUniversity of Chicago Medical Center·JournalDiabetes Care·DateApr 18, 2011
A new probiotic treatment has been shown to reduce the rate of recurrent urinary tract infections in women. The study found that women who received a Lactobacillus crispatus intravaginal suppository had lower infection rates compared to those who received a placebo.
SourceInfectious Diseases Society of America·JournalClinical Infectious Diseases·DateApr 15, 2011
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers found that a subgroup of PPMS patients can convert to PRMS, with faster disease progression and increased risk for sustained disability. The study emphasizes the need for clinicians to consider evaluating this subgroup differently in assessing prognosis and clinical course.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·DateApr 14, 2011
A randomized trial comparing three types of exercise training found that low-intensity treadmill exercise resulted in the most consistent improvements in gait and mobility for people with Parkinson's disease. Stretching and resistance exercises also showed some benefits.
Nine patients with amyotrophic lateral sclerosis (ALS) were treated with Neuralstem's spinal cord stem cells, showing no unresolved serious adverse reactions or death. The trial indicates the feasibility of transplanting stem cells directly into the spinal cord, paving the way for future treatments.
A new point-of-care clinical trial approach is being tested, combining statistical validity with real-world applicability to compare treatments. The approach aims to deliver the best care to patients while learning from each experience, reducing costs and time involved in traditional clinical trials.
SourceStanford Medicine·JournalClinical Trials·DateApr 8, 2011
A worldwide trial is being conducted to assess the use of robotic-assisted keyhole surgery in removing bowel tumours. The study aims to evaluate whether this approach makes cancer less likely to come back and reduces complications for patients.
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
The phase I safety trial of Neuralstem's human spinal cord stem cells in amyotrophic lateral sclerosis (ALS) will be presented at the American Academy of Neurology Annual Meeting, featuring interim safety data on nine patients. The trial is designed to evaluate the safety of the cells and surgery procedure for ALS treatment.
A longer-term follow-up of postmenopausal women who used estrogen therapy for 6 years found that the increased risk of stroke during treatment had dissipated, while the decreased risk of breast cancer persisted. The risk of hip fracture was not maintained during the postintervention phase.
A landmark study has found that radial access for angioplasty is a safe and effective alternative to traditional femoral access, resulting in fewer vascular complications and similar success rates. The RIVAL trial involved over 7,000 patients and compared radial and femoral access for coronary angiography and intervention.
SourceMcMaster University·JournalThe Lancet·DateApr 4, 2011
A Phase II dose-ranging study of BMS-790052 plus PEG-interferon alfa and ribavirin showed higher rates of sustained virologic response compared to PEG-interferon alfa and ribavirin alone. The regimen achieved up to 92% SVR12 in treatment-naïve patients with hepatitis C genotype 1.
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Clinical trials confirm efficacy and safety of new protease inhibitors in combination with PegIFN-alpha and ribavirin for HCV patients who have previously failed therapy. The treatments demonstrated good response rates at key timepoints and remarkably high sustained viral response rates.
SourceEuropean Association for the Study of the Liver·DateApr 1, 2011
A study published in The Lancet found that properly trained auxiliary nurse midwives and nurses can administer safe, low-technology medical abortion services as effectively as doctors. This could expand access to safe abortion services in developing countries where unmet need is greatest.
A woman with tetraplegia has controlled a computer cursor accurately for over 1,000 days using the BrainGate neural interface system. The system, which decodes brain signals to translate them into digital instructions, has shown promising results in enabling people with paralysis to control external devices.
SourceBrown University·JournalJournal of Neural Engineering·DateMar 24, 2011
Researchers argue that current rules requiring written consent in emergency situations are causing unnecessary delays, resulting in patients missing out on life-saving treatments. The study found that up to one sixth of patients in a major clinical trial were denied treatment due to these regulations.
SourceLondon School of Hygiene & Tropical Medicine·JournalThe Lancet·DateMar 23, 2011
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
The American Thoracic Society has released updated guidelines for diagnosing and managing idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung disease. The new guidelines emphasize evidence-based recommendations for diagnosis, pharmacologic and non-pharmacologic therapies, and palliative care.
SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateMar 17, 2011
The company's lead drug candidate, omecamtiv mecarbil, directly activates cardiac myosin, increasing cardiac function without changing contraction rates. This novel mechanism may provide a new therapeutic strategy for improving cardiac performance in patients with systolic heart failure.
A large randomized control trial found no evidence that osteopathic therapy improves movement, quality of life, or pain in children with cerebral palsy. However, parents whose children received osteopathy reported a slightly better overall wellbeing for their child compared to those who did not receive treatment.
SourceThe Peninsula College of Medicine and Dentistry·JournalArchives of Disease in Childhood·DateMar 14, 2011
A randomized trial suggests that preoperative colonic stenting offers no clear benefit over emergency surgery for patients with colorectal cancer and acute malignant left-sided colonic obstruction. The study found a high rate of tumor perforations, which may worsen clinical outcomes.
SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateMar 11, 2011
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Women with DCIS who develop invasive breast cancer in the same breast have higher mortality rates, study finds. Radiation treatment after lumpectomy reduces risk of ipsilateral invasive breast cancer, while treatment with tamoxifen also offers protection.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateMar 11, 2011
Researchers propose collaborative clinical trials to revitalize the US research engine, cutting time and costs while increasing approved treatments. The approach involves companies sharing costs to test new therapies or devices, promising safer and more effective treatments sooner.
SourceUniversity of Rochester Medical Center·JournalNew England Journal of Medicine·DateMar 2, 2011
Researchers found that the vaccine-induced cellular immune response exerted selective pressure on the virus, leading to changes in its genetic makeup. The study identified potential T-cell targets and proposed a new design for vaccines aimed at debilitating viruses.
SourceUniversity of Washington·JournalNature Medicine·DateMar 1, 2011
PSA screening has declined in a US healthcare network following the publication of large trials and guidelines. The decline was observed among men aged 40-54, 55-74, and 75 years and older, with decreases of 3%, 2.7%, and 2.2 percentage points, respectively.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateFeb 24, 2011
At least one dengue vaccine could be licensed within the next 4 years. Developing countries' national regulatory authorities (NRAs) have a crucial role in accelerating the licensure process when a new dengue vaccine becomes available.
SourceInternational Vaccine Institute·JournalPLOS Medicine·DateFeb 22, 2011
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A recent study found that passwords used to protect sensitive files in clinical trials are poorly constructed and easily cracked, putting personal health information at risk. The study recommends enforcing strong passwords and encryption algorithms to secure file sharing practices.
SourceChildren's Hospital of Eastern Ontario Research Institute·JournalJournal of Medical Internet Research·DateFeb 16, 2011
A recent study of 336 children with eczema found that installing a water softener did not improve symptoms, contradicting anecdotal reports. The trial, led by the University of Nottingham, suggested that hard water may worsen eczema due to high levels of calcium and magnesium.
SourceUniversity of Nottingham·JournalPLOS Medicine·DateFeb 16, 2011
A systematic review published in The Cochrane Library found that zinc supplements reduce the severity and duration of illness caused by the common cold. Zinc syrup, lozenges or tablets taken within a day of symptom onset reduced symptoms severity and length of illness.
SourceWiley·JournalCochrane Database of Systematic Reviews·DateFeb 15, 2011
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A new study by Duke University researchers has found that home-based physical therapy is an effective way to help stroke survivors regain mobility, with similar results to specialized locomotor training programs. The study, which compared home exercise with body-weight supported treadmill training, found that both approaches led to sig...
A small proportion of adult cancer patients participate in clinical trials due to low physician referrals. Medical and radiation oncologists were more likely to refer patients, as well as those in larger practices and academic appointments.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateFeb 11, 2011
A study published in Journal of Hospital Medicine found no significant difference in bacterial and MRSA contamination between long- and short-sleeved physician workwear. After an eight-hour day, nearly 50% of bacteria present at the start were already present on the uniforms by three hours.
SourceWiley·JournalJournal of Hospital Medicine·DateFeb 10, 2011
The eight-year trial shows prenatal surgery reduces fluid diversion needs, improves mental development and motor function, and increases the likelihood of a child walking unassisted. Fetal surgery is now considered a better option than waiting for corrective surgery after birth for patients with myelomeningocele.
SourceUniversity of California - San Francisco·JournalNew England Journal of Medicine·DateFeb 9, 2011
A landmark study by the Children's Hospital of Philadelphia shows fetal surgery for spina bifida can improve outcomes for children with the condition. Fetal surgery significantly reduced the need to divert fluid from the brain, improved mobility, and increased the chances that a child will be able to walk independently.
SourceChildren's Hospital of Philadelphia·JournalNew England Journal of Medicine·DateFeb 9, 2011
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
A new study led by UCSF found that the HPV vaccine can prevent 90 percent of genital warts in men when offered before exposure to the four HPV strains covered by the vaccine. The vaccine also showed a nearly 66 percent effectiveness rate in the general population of young men, regardless of prior exposure.
SourceUniversity of California - San Francisco·JournalNew England Journal of Medicine·DateFeb 4, 2011
A UofL-led consortium has been awarded $9.56 million to form the first-ever multicenter cardiovascular research network, studying cardioprotective therapies at the preclinical level. The four-center project aims to identify effective therapies and advance them to clinical trial stage.
A systematic review by the Peninsula College of Medicine and Dentistry has found that exercising outdoors improves mental well-being, with participants reporting greater feelings of revitalisation and positive engagement. However, further research is needed to fully understand the effects of outdoor exercise on physical well-being.
SourceThe Peninsula College of Medicine and Dentistry·DateFeb 4, 2011
Researchers redefine remission in rheumatoid arthritis by introducing two new provisional definitions that aim to standardize treatment goals. The new definitions focus on disease activity measures, including tender joint count, swollen joint count, and C-reactive protein levels.
SourceWiley·JournalArthritis & Rheumatism·DateFeb 3, 2011