Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
A new study shows that susceptibility-weighted imaging (SWI) is a powerful tool for characterizing infarctions in patients earlier, directing more prompt treatment. SWI detected thromboemboli in 30 patients out of 35 with thromboembolic infarctions, improving the classification of cerebral infarctions.
A new study finds that MDCT arthrography is more accurate than MR arthrography in detecting labro-ligamentous injuries, glenoid cartilage lesions, and Hill-Sachs fractures related to anterior shoulder instability. The imaging modality also shows high sensitivity for identifying glenoid rim fractures.
A new screening tool has been introduced to identify subtle signs of autism in 1-year-old children during well-baby check-ups. The 5-minute checklist is designed to be adopted by pediatricians nationwide and has shown high accuracy rates, enabling early diagnosis and treatment.
A study published in PLoS Medicine reveals that medical personnel at Guantánamo Bay failed to investigate and document causes of physical injuries and psychological symptoms in detainees. The review of nine cases corroborates allegations of torture, highlighting a breach of fundamental human rights.
Researchers have identified GM-CSF as a driving force behind autoimmune diseases like MS. Blocking its activity may lead to new treatments for the disease. Dr. Abdolmohamad Rostami and his team found that GM-CSF is responsible for disease manifestation in an experimental animal model.
A recent study by American Academy of Orthopaedic Surgeons highlights the lack of knowledge about osteoporosis among certain patient groups, increasing their risk of fractures. Patients with fragility fractures, male individuals, and those who are unemployed or have limited English proficiency tend to know less about osteoporosis.
The ESHRE Guide aims to ensure equitable and safe assisted reproduction treatment for local and foreign patients. Key principles include patient-centeredness, timeliness, and effectiveness, with recommendations on translator costs, donor compensation, and recruitment criteria.
A two-pronged molecular therapy combining inosine and NEP1-40 restores skilled motor function in a rat model of stroke. The study demonstrates significant nerve growth and functional improvements after treating strokes with this combination therapy.
Researchers at University of Western Ontario developed a strategy to stimulate blood vessel formation in tissues lacking oxygen, potentially treating conditions like coronary artery disease. The approach, using fibroblast growth factor 9 (FGF9), activates supporting cells that create functional new vessels that last over a year.
Researchers found that a subgroup of PPMS patients can convert to PRMS, with faster disease progression and increased risk for sustained disability. The study emphasizes the need for clinicians to consider evaluating this subgroup differently in assessing prognosis and clinical course.
A Mayo Clinic case study finds Botox effective in treating disabling low cerebrospinal fluid headaches. The patient's headaches improved significantly after receiving Botox treatments, allowing her to live a more normal life.
Researchers at Johns Hopkins Bloomberg School of Public Health developed a non-steroid based strategy to improve lung's innate immune defense against bacterial infection in COPD patients. Sulforaphane, an ingredient present in broccoli, was used to enhance the Nrf2 pathway in the lungs.
A new study published in Biotechnology Journal reveals a cheaper and more efficient method for treating dyed denim, eliminating the need for hazardous sandblasting techniques. The surface activation technique reduces fabric strength decay, shortens wash-down processes, and minimizes chemical usage.
A new study led by Emory psychologist Stella Lourenco found a clear relation between claustrophobic fear and basic aspects of spatial perception. People with higher claustrophobic fear have an exaggerated sense of near space surrounding them.
Storing fruits and vegetables in ozone-enriched environments significantly reduces microbial spoilage, with up to 95% disease prevention after 8 days. Ozone treatment is a viable alternative to pesticides, leaving no residues on foods.
Scientists are investigating a novel treatment approach for traumatic optic nerve damage, with the goal of preventing permanent vision loss. By targeting an enzyme that regulates adenosine production, researchers hope to strengthen the body's natural anti-inflammatory response.
The National Heart, Lung, and Blood Institute (NHLBI) has awarded $383,000 to nine state and local organizations to enhance COPD education initiatives across the country. These organizations will focus on increasing awareness among at-risk populations and enhancing leadership for prevention and treatment.
The Society of Interventional Radiology Foundation has received a major corporate pledge of $500,000 from Navilyst Medical to support its Discovery Campaign. This funding will be used to support grants, research consensus panels, registries, studies addressing comparative effectiveness, clinical trials, and educational programming.
A new therapy program using virtual reality and scents like smoke and spices helps servicemen recover from wartime experiences. Researchers seek to reduce flashbacks and anxiety in veterans diagnosed with post-traumatic stress disorder (PTSD).
The new stereo-EEG method enables exact localization of functionally important brain areas, improving the safety of epilepsy surgery. The technique also provides a more pleasant experience for patients, with thin recording electrodes placed through small holes.
A minimally invasive procedure, pelvic arterial embolization is a safe and effective treatment for postpartum hemorrhage, preserving the uterus and allowing resumption of menstruation. The study showed an initial clinical success rate of 86 percent, with repeat procedures increasing the overall bleeding control to 97.8 percent.
Researchers argue that current rules requiring written consent in emergency situations are causing unnecessary delays, resulting in patients missing out on life-saving treatments. The study found that up to one sixth of patients in a major clinical trial were denied treatment due to these regulations.
Researchers found that early treatment within an hour of injury reduced mortality by over 30% compared to placebo, while delayed treatment beyond 3 hours showed no benefit and possible harm. Tranexamic acid's benefits were also observed in patients who received treatment between one and three hours post-injury.
A recent study published in Archives of Facial Plastic Surgery found that periocular treatment significantly improved overall quality of life for patients with facial paralysis. The treatment also reduced symptoms of dryness and irritation around the eyes.
The Government of Canada has announced a breakthrough in producing an affordable and reliable malaria treatment, expected to treat 200 million cases and prevent over one million deaths annually. The new technology is the result of a public-private partnership led by OneWorld Health and will be made available on a not-for-profit basis.
A study of 523 patients aged 6-17 years found that non-operative sealing of manifest occlusal caries lesions resulted in a significant reduction in caries progression and improvement in tooth health. The results indicate the possibility of extending the criteria for non-operative sealing, but further observation is needed.
Researchers at the University of Granada have found that early neuropsychological rehabilitation significantly reduces cognitive, emotional, and behavioral after-effects in patients with acquired brain injury. The study proves that treating cognitive, emotional, and behavioral skills simultaneously improves patient outcomes.
An updated systematic review finds that artesunate is more effective at preventing death from severe malaria compared to quinine. The new evidence shows a significant reduction in mortality rates among both adults and children treated with artesunate.
A new, multifunctional catheter developed by Northwestern University and the University of Illinois can perform all necessary medical devices for cardiac ablation therapy in one minimally invasive procedure. The device combines diagnostic and treatment capabilities, improving clinical arrhythmia therapy by reducing steps and costs.
Scientists have found fluoride forms a protective shield on teeth that is only 6 nanometers thick, sparking doubts about its ability to fight cavities.
Millions of people worldwide may be at risk of early death from diabetes due to poor diagnosis and ineffective treatment. In the US, nearly 90% of adult diabetics have blood sugar, blood pressure, and cholesterol levels not treated effectively.
A new study published in Psychological Science finds that a short-term regime called cognitive-bias modification can help heavy drinkers change their impulsive responses to temptation, leading to improved treatment outcomes. The technique involves video-game-like tasks and was found to reduce relapse rates among alcoholics.
A University of Colorado Boulder study indicates acupressure may improve cognitive function in individuals with mild traumatic brain injury. Researchers used a form of acupuncture called Jin Shin to stimulate specific points on the body and showed significant improvements in working memory and attention.
A strain of probiotic bacteria, Bifidobacterium bifidum CECT 7366, has been identified as effective in treating ulcers caused by Helicobacter pylori. The probiotic strain demonstrated significant inhibition levels against H. pylori and partially relieved damage to gastric tissue.
Researchers discovered unique spinal fluid proteins that differentiate neurologic post-treatment Lyme disease (nPTLS) and chronic fatigue syndrome (CFS), indicating central nervous system abnormalities. The study provides a starting point for diagnostic biomarkers and potential treatment targets.
Parasitic protozoons like Cryptosporidium and Giardia can survive water treatment systems, posing a significant risk to human and animal health. The study highlights the need for better preventive measures, including protecting water sources, monitoring water quality, and implementing control plans.
Researchers have identified a new cellular mechanism underlying hydronephrosis by studying kidney development in mice. Genetic mutations in the Hedgehog signaling pathway impaired urine flow from the kidney to the bladder, leading to hydronephrosis.
Asthma affects 8% of Americans and 300 million worldwide, but global variations in diagnosis and treatment have significant implications. Researchers are exploring how cultural factors impact asthma management, including the use of different terms to describe symptoms and varying levels of parental involvement.
A new trial confirms that CBT and GET are safe and moderately effective outpatient treatments for chronic fatigue syndrome, improving symptoms more than adaptive pacing therapy or specialist medical care alone. Serious adverse reactions were rare across all treatment groups.
The US military faces a growing crisis of suicide among its personnel, with rates increasing sharply since 2001. To address this issue, researchers recommend improving access to quality behavioral health care and raising awareness about the importance of seeking help.
A study published in Journal of Traumatic Stress found that virtual reality exposure therapy significantly reduced PTSD symptoms in active duty military service members, with 62% reporting clinically meaningful change. The innovative treatment uses multi-sensory virtual reality to safely access and process traumatic memories.
A study by Kim Thomas and colleagues found that ion-exchange water softeners do not improve eczema severity scores or symptoms, such as sleep loss and itchiness, in children with moderate to severe eczema. However, parents reported small health benefits and over 50% chose to install a water softener due to perceived improvements.
Researchers found that using non-alcohol antibacterial mouthwash containing cetylpyridinium chloride (CPC) decreases the incidence of preterm birth. The study, funded by The Procter & Gamble Company, involved pregnant women with periodontal disease who received either treatment or a control group.
Cardiac resynchronization therapy significantly reduces mortality among patients with mildly symptomatic or advanced heart failure, improving long-term outcomes. The addition of CRT to optimal medical therapy or ICDs can be extended to a wider proportion of patients, benefiting the growing population affected by heart failure.
Researchers use vagus nerve stimulation paired with sound tones to retrain the brain and reduce ringing in the ears. After 20 days of treatment, tinnitus disappeared in noise-exposed rats, persisting for up to 3.5 months.
A Mount Sinai study found a significant increase in the rate of 'sarcoid-like' granulomatous pulmonary disease among World Trade Center (WTC) responders compared to pre-9/11 FDNY personnel. The condition was associated with environmental exposures and lung function abnormalities.
Researchers in India have found that various kitchen waste water filtration systems can produce clean water suitable for agricultural or horticultural use. Ceramic microfiltration membrane systems with physicochemical treatments such as biotreatment and adsorption showed promising results, removing up to 98% of BOD and 99% of COD.
Researchers found a communication intervention effective in reducing ICU stays for chronic patients but less so for surgical and neurological cases. The study highlights the need for tailored approaches to support families making critical decisions for their loved ones.
A randomized controlled trial shows that CPAP therapy significantly reduced self-reported fatigue scores and increased energy levels in patients with OSA. Participants who received therapeutic CPAP experienced significant improvements in fatigue and energy, while those on placebo showed no changes.
A new study from the University of Gothenburg estimates that approximately 2% of the population in West Sweden suffers from severe asthma, which is characterized by nasal congestion. The study suggests that patients with nasal complaints should be investigated for asthma, as more pronounced symptoms may be linked to severe asthma.
Scientists challenge conventional wisdom on fluoride's effectiveness in preventing tooth decay, finding the protective shield on teeth is just 6 nanometers thick, sparking questions about its ability to protect teeth.
A study found that acupuncture improved visual acuity in older children with lazy eye, comparable to patching therapy. Acupuncture was well-tolerated and showed promising results in treating anisometropic amblyopia.
A recent study by University of Pittsburgh researchers suggests that nonchemical treatment devices may not be effective in controlling bacterial growth in water-based cooling systems. The two-year study found that standard chlorine treatment controlled the organisms even after they had proliferated.
The new guidelines aim to standardize diagnosis, treatment, and management of food allergies. They consolidate the latest available data into straightforward and consistent protocols for diagnosis and treatment, which will give physicians a uniform pool of information, ultimately leading to more accurate care for patients.
Researchers found that private insurance paid for healthcare costs in the under-65 population significantly reduced disparities in per-capita Medicare healthcare spending between McAllen and El Paso. For this age group, inpatient admissions were 89% higher in McAllen than El Paso, but outpatient medical service spending was 22% lower.
A new study by the University of Utah found that the LouseBuster is highly effective in killing head lice and nits, with 94.8% mortality rate. The device uses warm air to dry out lice and nits, making it a safe and easy treatment option.
A $7 million grant from the Bill & Melinda Gates Foundation will support a four-year research project to develop clinical guidelines for pre-eclampsia diagnosis and treatment in lower- and middle-income countries. The project aims to reduce maternal, fetal, and newborn deaths related to pre-eclampsia.
A new study by Ben-Gurion University of the Negev has shown that individually tailored dietary treatment for acutely hospitalized elderly can significantly reduce mortality rates. The study found a 64% decrease in death rates among those receiving intensive nutritional treatment compared to the control group.
Researchers developed a new treatment for sudden sensorineural hearing loss (SSHL) using insulin-like growth factor 1 (IGF1) gelatin hydrogels, with 48% of patients showing hearing improvement at 12 weeks and 56% at 24 weeks.
A team of researchers has successfully treated beta-thalassemic mice by increasing hepcidin levels, which limits iron overload and markedly reduces anemia. This approach suggests a new therapeutic strategy for patients with beta-thalassemia, potentially mitigating iron overload and anemia.