A leading expert suggests that taking patients in cardiac arrest to hospital may be actively harmful and recommends empowering ambulance staff with skills to optimise CPR at the scene. This approach could save lives and reduce unnecessary transports, but experts acknowledge the complexity of applying guidelines in different regions.
A new study found lower testosterone levels in men with sudden cardiac arrest and higher estradiol levels in both men and women were associated with increased risk. The research suggests that hormone levels may play a role in predicting patients' likelihood of suffering from the usually fatal condition.
SourceCedars-Sinai Medical Center·JournalHeart Rhythm·DateSep 2, 2014
A new method predicts the optimal number and location of automated external defibrillators (AEDs) in public places to prevent out-of-hospital cardiac arrests. The study suggests that approximately 350 AEDs are needed in Paris to achieve optimal prevention, with a focus on geographic optimization modeling.
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A new study found that staff members who joined structured team debriefings after emergency care for children suffering in-hospital cardiac arrests improved their CPR performance. The study also showed substantial increases in patients surviving with favorable neurological outcomes, up to 50 percent among the intervention group.
SourceChildren's Hospital of Philadelphia·JournalCritical Care Medicine·DateAug 4, 2014
A new Arizona EMS system dramatically increased cardiac arrest survival rates, with a 60% increase in four-year period. The system sent patients to specialized cardiac receiving centers, significantly improving neurological outcomes and survival chances.
SourceAmerican College of Emergency Physicians·JournalAnnals of Emergency Medicine·DateJul 25, 2014
Bystander cardiopulmonary resuscitation increases survival by 2-3 times but is delivered in only 1 in 5 out-of-hospital cardiac arrests across Europe. Improving education for schoolchildren and dispatchers could save thousands of lives.
SourceThe European Society of Anaesthesiology and Intensive Care (ESAIC)·DateJun 1, 2014
A large Japanese study found that dispatcher-assisted bystander CPR increased the delivery rate of CPR and was associated with improved neurological and overall outcomes. Children who received dispatcher-assisted CPR had a significantly higher chance of survival and better brain function compared to those who did not receive CPR.
A study found that 76.2% of older adults prefer administration of clot-dissolving medications in case of a stroke, supporting the use of this treatment when surrogate consent is not available. Lower education and poorer health were associated with refusal of thrombolysis.
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Research at St. Michael's Hospital found that administering adrenaline after a cardiac arrest outside of a hospital does not improve long-term survival rates, despite its long-standing use as treatment for decades. The study suggests alternative methods such as early defibrillator use and effective CPR may be more beneficial.
SourceSt. Michael's Hospital·JournalResuscitation·DateApr 17, 2014
A large US study found that cardiac arrest during childbirth is more common than thought, with causes including excessive bleeding, heart failure, and amniotic fluid embolism. The survival rate improved from 52% to 60% between 1998 and 2011.
SourceAmerican Society of Anesthesiologists·JournalAnesthesiology·DateMar 18, 2014
A study found that public defibrillators are underutilized in England, with only 1.74% of cardiac arrests being treated with the device. The authors suggest that more education and placement of defibrillators in public areas could improve survival rates.
Researchers at the Cardiovascular Institute found that unfolded protein response contributes to sudden cardiac death in heart failure. Blocking this response may significantly reduce the risk of sudden cardiac death.
Middle-age men in Portland, Oregon, experienced symptoms such as chest pain, shortness of breath, and dizziness prior to heart stops. Prompt CPR can increase survival chances for these cardiac arrests.
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A recent study led by Lund University researchers has found that therapeutic hypothermia treatment for cardiac arrest is just as effective at a body temperature of 36°C as it is at 33°C, without the increased risk of side effects. This finding has important implications for patient rehabilitation and recovery after cardiac arrest.
SourceLund University·JournalNew England Journal of Medicine·DateNov 18, 2013
A study from Duke University Medical Center found that rural and southern US counties have low rates of annual CPR training. These communities are often far from hospitals, and lower CPR training rates contribute to higher heart disease mortality rates.
SourceDuke University Medical Center·JournalJAMA Internal Medicine·DateNov 18, 2013
A trial of 1,359 cardiac arrest patients found that prehospital cooling did not improve survival to hospital discharge or neurological outcome. The intervention reduced core temperature by more than 1°C, but the results do not support routine use of cold intravenous fluid in the prehospital setting.
A multicenter clinical trial compared mechanical chest compressions with manual CPR and found that neither approach improved 4-hour survival rates. However, patients receiving mechanical chest compressions had a higher proportion of survivors with good neurological outcomes, suggesting potential benefits in specific patient populations.
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Research presented at American Heart Association's Scientific Sessions 2013 found hospitalized children under 18 have lower survival rates during night shifts. Thirty-four percent of children survived after cardiac arrest on day or evening shifts, compared to 11 p.m.-6:59 a.m. where only 34% survived.
A study found that CPR for 38 minutes or longer can improve a patient's chances of surviving cardiac arrest. Sustaining CPR for this extended period also reduces the risk of severe brain damage and preserves normal brain function.
Researchers in the UK found that organs from selected DCD donors with pre-hospital cardiac arrest had no significant impact on graft or transplant recipient survival compared to other deceased donors. The study suggests using these organs could boost the donor pool without adverse outcomes for liver transplant recipients.
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A nationwide study in Denmark found an increase in bystander cardiopulmonary resuscitation (CPR) and subsequent survival rates, with a significant rise in 30-day and 1-year survival rates. Bystander CPR was positively associated with improved outcomes.
A new study found that only 12 out of 92 eligible patients received an implantable cardiac defibrillator after being medically evaluated. The majority who qualified did not receive the treatment, highlighting a need for further analysis to determine why this occurs.
SourceCedars-Sinai Medical Center·JournalCirculation·DateSep 24, 2013
A study of 2,589 patients found that mechanical chest compressions with defibrillation did not improve survival rates compared to manual CPR. However, the device was deemed safe and showed promise in increasing efficiency and safety for emergency personnel.
Research presented at ESC Congress 2013 found that out-of-hospital cardiac arrest survival rates are low, with only 7% of patients surviving. Therapeutic hypothermia and early coronary reperfusion were both linked to improved survival outcomes in patients.
A University of Michigan study reveals that rats display brain activity patterns characteristic of conscious perception shortly after clinical death. The findings suggest that the brain is capable of well-organized electrical activity during the early stage of clinical death.
SourceMichigan Medicine - University of Michigan·JournalProceedings of the National Academy of Sciences·DateAug 12, 2013
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A new study found that people experiencing sudden cardiac arrest at exercise facilities have a higher chance of survival than at other indoor locations. The study looked at 849 cases in Seattle and King County, Wash., and found that traditional exercise facilities had the highest survival rates.
SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateAug 7, 2013
A randomized clinical trial found that combination therapy using vasopressin-epinephrine during cardiopulmonary resuscitation and corticosteroid supplementation improved survival to hospital discharge with a favorable neurological score. This study suggests increased efficacy of the combination therapy compared to epinephrine alone dur...
A study found that only 2% of hospital cardiac arrest patients received therapeutic hypothermia, despite its proven potential to improve survival and neurological function. The lack of data and guidelines may contribute to the low use of this treatment.
SourceUniversity of Pennsylvania School of Medicine·JournalCritical Care Medicine·DateJun 21, 2013
A new study published in the American Heart Association journal Circulation found that elderly patients can benefit from implantable cardioverter defibrillators (ICDs) just like younger individuals. The study of 5,399 patients revealed that older patients were as likely to experience life-threatening electrical shocks but had higher ra...
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Resuscitation efforts should be guided by expert advice, taking into account scenarios where CPR may not be beneficial. Key considerations include witness status, time elapsed since cardiac arrest, patient wishes expressed through living wills or proxies, and potential risks to medical personnel.
SourceThe European Society of Anaesthesiology and Intensive Care (ESAIC)·DateJun 1, 2013
A study published in JAMA Internal Medicine found that hospitals with higher case-survival rates for cardiac arrests also had lower incident rates. The research analyzed data from 358 hospitals and identified a correlation between preventing cardiac arrests and survival rates.
SourceJAMA Network·JournalJAMA Internal Medicine·DateMay 20, 2013
A new study by University of Michigan researchers found that hospitals with the highest rates of cardiac arrests tend to have the poorest survival rates for those cases. Conversely, hospitals that do a better job preventing cardiac arrest among patients also tend to save more patients who experience an arrest.
SourceMichigan Medicine - University of Michigan·JournalJAMA Internal Medicine·DateMay 20, 2013
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Researchers at the University of Pennsylvania School of Medicine found promising results in using Extracorporeal Membrane Oxygenation (ECMO) to treat select patients with refractory cardiac arrest and profound shock. The study, which included 33 patients, showed a survival rate of 21% and five patients were neurologically intact.
SourceUniversity of Pennsylvania School of Medicine·DateMay 17, 2013
A new mathematical formula developed by researchers at St. Michael's Hospital and the University of Toronto identifies high-risk areas for cardiac arrests and suggests optimal locations for automated external defibrillators (AEDs) to maximize survival rates.
SourceSt. Michael's Hospital·JournalCirculation·DateMay 2, 2013
A new mathematical model developed by researchers at the University of Toronto can pinpoint high-risk areas for cardiac arrests and recommend optimal placement of defibrillators. According to the study, nearly three times as many public cardiac arrests occurred in downtown Toronto than in the rest of the city.
SourceUniversity of Toronto Faculty of Applied Science & Engineering·JournalCirculation·DateMay 2, 2013
A University of Michigan study found that survival from cardiac arrest is higher when it occurs in the operating room (O.R.) or post-anesthesia care unit (PACU) compared to other hospital locations. The presence of anesthesia providers in these areas may improve outcomes for certain patients.
SourceMichigan Medicine - University of Michigan·JournalAnesthesiology·DateMay 1, 2013
A recent study by Beaumont doctors highlights the importance of training and emergency response planning in K-12 schools to reduce sudden cardiac arrest fatalities. The study found that bystander use of automated external defibrillators (AEDs) increases survival rates threefold, emphasizing the need for standardized training and drills.
SourceBeaumont Health System·JournalResuscitation·DateMar 28, 2013
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A European Society of Cardiology initiative aims to train bystanders in CPR to increase survival rates. Studies show that trained individuals are ten times more likely to respond than untrained ones, and training makes a big difference.
A Japanese study found that lactated Ringer's solution, commonly used as a pre-hospital treatment for cardiac arrest, is associated with a decreased chance of survival with minimal neurological or physical impairment. The study analyzed data from over half a million patients and suggested that alternative fluids may be more beneficial.
Researchers found a positive correlation between out-of-hospital cardiac arrests and exposure to both fine particulate matter and ozone in Houston. Daily average increases in particulate matter raised OHCA risk by 4.6 percent, while short-term increases in ozone level increased risk by 4.4 percent.
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A recent study published in Circulation found that longer CPR durations can extend survival in children and adults after hospital cardiac arrests. The research team analyzed data from thousands of patients and discovered that more children than expected survived prolonged CPR, with over 60% having good neurologic outcomes.
A crowdsourcing contest led to the identification of over 1,400 automated external defibrillators in public places, providing crucial data for quick bystander response to out-of-hospital cardiac arrests. Public education remains a key priority to improve use of AEDs.
SourceUniversity of Pennsylvania School of Medicine·DateNov 4, 2012
A Japanese study presented at the American Heart Association's Scientific Sessions 2012 found that family members were least likely to administer CPR after a cardiac arrest, but most likely to receive telephone instructions. Researchers attributed this to cultural and demographic issues in Japan, including a large gender gap.
A study by Dr. Paul Dorian found that the risk of cardiac arrest depends on where you live, with neighborhoods having higher rates experiencing three to five times more cases than those with lower rates. Wealth, education, and social inclusion are important factors in determining cardiac arrest risk, but only explain part of the puzzle.
SourceHeart and Stroke Foundation of Canada·DateOct 30, 2012
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A study found 174 cases of sudden cardiac death in Ontario between ages 2-40, with heart disease present in 72% of cases. The majority of events occurred at home, not during sports or exercise. Researchers advocate for screening and education to detect warning signs like fainting.
SourceHeart and Stroke Foundation of Canada·DateOct 29, 2012
Researchers found a direct relationship between neighborhood income and racial composition and the probability of receiving bystander-initiated CPR. The study suggests that targeted, low-cost CPR training efforts are needed to address disparities in life-saving interventions.
SourceUniversity of Colorado Anschutz Medical Campus·JournalNew England Journal of Medicine·DateOct 24, 2012
Researchers found that residents in high-income white and integrated neighborhoods were more likely to receive bystander CPR during out-of-hospital cardiac arrests compared to those in low-income black neighborhoods. The study suggests a targeted approach in these areas may be more efficient than nationwide CPR training programs.
SourceEmory Health Sciences·JournalNew England Journal of Medicine·DateOct 24, 2012
The study found that urgent coronary angiography and PCI improved hospital survival rates in patients with STEMI and NSTEMI. Successful treatment increased survival rates from 51% to 83% for STEMI and 55% to 81% for NSTEMI.
The study found that patients treated in states with public reporting of PCI outcomes were less likely to receive a PCI compared to those in non-reporting states. However, there was no difference in overall heart attack survival rates between the two groups.
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Researchers found that patients at hospitals with longer resuscitation attempts have a higher likelihood of immediate survival and survival to discharge. However, the study does not recommend an optimal duration for resuscitation, emphasizing the need for careful clinical judgment.
SourceMichigan Medicine - University of Michigan·JournalThe Lancet·DateSep 4, 2012
A study examining the length of resuscitation efforts after in-hospital cardiac arrest found that hospitals attempting longer resuscitations had higher survival rates. The duration of resuscitation attempts varied widely between hospitals, with those attempting longer efforts having a greater chance of successful revival and discharge.
SourceThe Lancet_DELETED·JournalThe Lancet·DateSep 4, 2012
Research presented at the ESC Congress 2012 found that patients who experience a cardiac arrest during or shortly after exercise are three times more likely to survive than those who experience an exercise-unrelated cardiac arrest. The study also showed that exercise-related cardiac arrests tend to occur in younger, male individuals an...
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Penn and Cornell researchers have created evidence-based guidelines for veterinary CPR, aiming to standardize treatment of cardiac arrest in pets. The guidelines recommend 100-120 chest compressions per minute, intubated ventilation at a rate of 10 breaths per minute, and administration of vasopressors every 3 minutes.
SourceUniversity of Pennsylvania·JournalJournal of Veterinary Emergency and Critical Care·DateJun 7, 2012
Researchers at Trinity College Dublin developed a patented technology to reduce cerebral oedema by safely manipulating blood vessels in the brain. The technique, 'Neuronal Barrier Modulation,' has shown promising results in animal models and is planned for Phase I clinical trials.
SourceTrinity College Dublin·JournalNature Communications·DateMay 22, 2012
A Penn study found that more than 75% of cardiac arrests occur outside the range of nearby automated external defibrillators (AEDs), highlighting the need for strategic placement and easy location. The study suggests innovative ways to help the public find AEDs in emergencies.
SourceUniversity of Pennsylvania School of Medicine·DateMay 11, 2012
Research reveals racial disparities in pre-hospital care for black cardiac arrest victims, with lower rates of bystander CPR and defibrillation. The study also found that black patients were less likely to have regained their pulse before arrival at the hospital.
SourceUniversity of Pennsylvania School of Medicine·DateMay 11, 2012
Researchers have identified a new way to predict the risk of sudden cardiac arrest by imaging nerve function in the heart. A study involving 204 patients with advanced heart disease found that those with at least 38% denervated myocardium were at highest risk of sudden cardiac arrest.
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A Mayo Clinic study found that therapeutic hypothermia, also known as body cooling, has reduced in-hospital deaths among sudden cardiac arrest patients. The research analyzed over 1 million patients and found mortality rates dropped from 69.6% to 57.8% between 2001 and 2009.
Research finds improved survival rates among patients with non-shockable cardiac arrests when given CPR based on updated guidelines. The likelihood of survival to discharge increased from 4.6% to 6.8%, and one-year survival doubled from 2.7% to 4.9%
Paramedics can administer a mixture of glucose, insulin and potassium (GIK) to patients having a heart attack, reducing the rate of cardiac arrest and death by 50 percent. The treatment also reduces the severity of heart tissue damage from the heart attack.
SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateMar 27, 2012