Articles tagged with Chronic Fatigue Syndrome
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A new report from the Institute of Medicine proposes revised diagnostic criteria for chronic fatigue syndrome, highlighting its physiologic nature. The criteria also emphasize the debilitating symptom of post-exertional malaise, where exertion triggers prolonged periods of fatigue.
A brain imaging study reveals differences in basal ganglia activity and similarity to inflammation-induced fatigue in chronic fatigue syndrome. Reduced basal ganglia activity is associated with the severity of fatigue symptoms.
Researchers used functional PET imaging to show that neuroinflammation is higher in CFS/ME patients compared to healthy people. The study found associations between inflammation in certain brain areas and symptoms such as impaired cognition.
The study aims to determine the prevalence of pediatric chronic fatigue syndrome in over 20,000 Chicago area youth ages 5 to 17. Chronic fatigue syndrome is an illness affecting close to 1 million Americans, causing significant impairment in physical functioning and daily activities.
Researchers found that cognitive behaviour therapy (CBT) and graded exercise therapy (GET), when combined with specialist medical care, can lead to significant improvements in symptoms and disability for patients with chronic fatigue syndrome. After one year, 22% of participants met the criteria for recovery, compared to 8% who receive...
Australian researchers discovered that reduced heart rate variability best predicts cognitive disturbances in people with chronic fatigue syndrome. The study found a significant loss of vagal modulation, consistent with the notion that CFS represents a system under stress. This could lead to new ways to improve cognitive difficulties i...
Researchers tested blood samples from 300 people for the presence of XMRV and pMLV genes, eliminating potential contamination that led to earlier false positives. No correlation between these viruses and chronic fatigue syndrome was found, refuting previous speculation.
A Mayo Clinic physiologist argues that lack of exercise should be treated as a medical condition, rather than just a cause or symptom of other health problems. This approach could lead to the development of treatments and public health measures to promote physical activity and limit sedentary behavior.
A new study finds that chronic fatigue syndrome patients have decreased activation of the basal ganglia in response to reward, associated with increased fatigue levels. The findings shed light on the biology of this mysterious disease and may lead to better treatments.
Researchers have developed a web-based therapeutic programme called Fatigue In Teenagers on the interNET (FITNET) that is substantially more effective than standard treatment in reducing symptoms of chronic fatigue syndrome. After 6 months, 63% of adolescents receiving FITNET reported recovery, compared to 16% on standard care.
Researchers at the University of Toronto Scarborough are studying how environmental factors affect gene expression in Chronic Fatigue Syndrome (CFS) patients. The study aims to identify epigenetic mechanisms that contribute to immune dysfunction and stress response in CFS, which could lead to new treatment options.
A new study suggests that Rituximab treatment can lead to significant improvement in CFS symptoms, potentially revealing a new direction for CFS research. The anti-CD20 antibody depletes B-lymphocytes, which are thought to be crucial in the disease's progression.
A Department of Health and Human Services-funded study confirms earlier findings were likely due to laboratory error, ruling out XMRV's presence in patients with chronic fatigue syndrome or healthy donors. The study suggests there is no need to screen blood donors for the viruses at present.
A new comment published in The Lancet states that numerous studies failed to replicate the findings of a 2009 XMRV detection in CFS patients. Contamination of laboratory reagents is blamed for the association between XMRV and chronic fatigue syndrome, leaving the field without a confirmed cause.
A new UCSF study finds no evidence of a mouse virus in human blood, contradicting previous claims that it caused Chronic Fatigue Syndrome. The study suggests the virus was detected in contaminated laboratory samples, and scientists need to continue searching for the real cause of the illness.
Researchers at the University of Utah Health conducted a comprehensive study finding no evidence of XMRV in CFS patients or healthy controls. The study's results contradict previous findings that linked the retrovirus to CFS, and experts emphasize the need for further research into potential infectious agents associated with the disease.
Researchers discovered unique spinal fluid proteins that differentiate neurologic post-treatment Lyme disease (nPTLS) and chronic fatigue syndrome (CFS), indicating central nervous system abnormalities. The study provides a starting point for diagnostic biomarkers and potential treatment targets.
A new trial confirms that CBT and GET are safe and moderately effective outpatient treatments for chronic fatigue syndrome, improving symptoms more than adaptive pacing therapy or specialist medical care alone. Serious adverse reactions were rare across all treatment groups.
A new study published in Retrovirology reveals that cell samples used in previous research were contaminated with XMRV, not the cause of chronic fatigue syndrome. The researchers developed improved methods to detect XMRV and rule out infection by this virus as a cause of the disease.
Researchers investigating UK samples have found no association between XMRV and chronic fatigue syndrome, contradicting a previous report. The study suggests that CFS may encompass a range of diseases and that further investigations are needed to confirm or rule out an association with XMRV infection.
A new UK study has found no evidence of the XMRV virus in patients with Chronic Fatigue Syndrome (CFS), contradicting previous findings that suggested a link. The research suggests that CFS treatment using anti-retroviral drugs may not be effective.
A study by Emory University School of Medicine and CDC found childhood trauma increases CFS risk six-fold, with posttraumatic stress disorder symptoms further exacerbating the risk. Low cortisol levels are also associated with childhood trauma, suggesting they may be a marker for CFS risk rather than a symptom
Individuals with childhood trauma are six times more likely to develop chronic fatigue syndrome as adults, according to a recent study. Childhood trauma is also associated with neuroendocrine dysfunction and decreased cortisol levels, suggesting a biological pathway that influences adult vulnerability to illness.
Chronic fatigue syndrome is linked to a stomach virus, with over 80% of infected patients testing positive for enteroviral particles. Research suggests that initial infections can occur years earlier, highlighting the long-term impact of viral infections on the condition.
A study of healthy women has found that stress-related cortisol administration can reduce fatigue and increase vigor. The research may help fine-tune treatments for illnesses linked to low cortisol levels, such as chronic fatigue syndrome and post-traumatic stress disorder.
Research suggests that chronic fatigue syndrome (CFS) is influenced by multiple factors, including neuroticism, introversion, and genetics. Cognitive behavioral therapy (CBT) and exercise therapy have been found to be effective in managing symptoms.
A study found that veterans with CMI report poorer quality of life and utilize more healthcare services. The condition is also linked to metabolic syndrome, which doubles the risk of coronary heart disease, diabetes, and cirrhosis.
A study published in the BMC Neurology Journal found that patients with chronic fatigue syndrome have a set of proteins in their spinal cord fluid not detected in healthy individuals. These proteins could serve as a 'biosignature' for the disease and may help diagnose CFS in the future.
A pilot study published in BMC Neurology identified 16 proteins in the cerebrospinal fluid of CFS patients that are not found in healthy individuals, potentially providing a biosignature for diagnosis. The study concludes that chronic fatigue syndrome may be a legitimate neurological disease.
Research reveals a significant increase in chronic fatigue syndrome and fibromyalgia among veterans of the first Gulf War compared to non-deployed peers. The study, conducted at 16 VA medical centers, found that deployed veterans were 40 times more likely to develop chronic fatigue.
A review of 29 studies found that 19.6% of chronic fatigue syndrome patients improved with inactive treatments, lower than expected figures for other conditions. Behavioral therapy and graded exercise therapy show benefits, but high patient expectations and a perceived physical origin may hinder treatment outcomes.
A randomized, double-blind trial found that galantamine hydrobromide did not provide a significant clinical benefit for patients with CFS. Despite being well-tolerated, the study confirmed the lack of effectiveness of this medication in addressing core symptoms.
A study found a higher prevalence of the D variant in the ACE gene among Gulf War veterans with chronic fatigue syndrome. Veterans with specific genetic variants were more likely to develop CFS/ICF, suggesting an interaction between genetics and environmental factors related to deployment.
Researchers link chronic fatigue syndrome to an impaired stress response, finding lower levels of a key hormone in patients. The study suggests that future research should investigate the role of cortisol in the condition.
Women with endometriosis have a higher prevalence of autoimmune inflammatory diseases, hypothyroidism, fibromyalgia, chronic fatigue syndrome, allergies, and asthma. A 10-year delay between symptom onset and diagnosis is common, prompting doctors to consider endometriosis in girls and women with pelvic pain.
A study of 250 primary-care patients found that infections like glandular fever can trigger chronic fatigue syndrome (CFS), while mood disorders are predicted by factors such as psychiatric history and social adversity. Early physical activity may help prevent or treat CFS after infectious mononucleosis.
A study published in Journal of the American Medical Association found that fludrocortisone had little effect on symptoms of chronic fatigue syndrome. The researchers tested isolating fludrocortisone as a treatment and found no significant improvement compared to a placebo.