Articles tagged with Heart Failure
Contemporary US heart failure mortality rates have surpassed those in 1999 due to reversals from 2012 to 2021. The COVID-19 pandemic may have accelerated these increases, partly due to healthcare access limitations.
Atrial fibrillation is more common and deadly among young Americans than previously believed, a new study found. The study of over 67,000 patients under 65 years old showed higher rates of hospitalization, stroke, heart attack, comorbidity, and mortality compared to their peers without Afib.
The American Association for Thoracic Surgery (AATS) and Cardiovascular Research Foundation (CRF) will collaborate on the development of New York Valves 2024, focusing on advances in surgical approaches and techniques in valve disease. The summit will feature expert discussions, live-case demonstrations, and hands-on training.
Researchers found that reticulon 3 (RTN3) is downregulated in left ventricular tissue of patients with heart failure after myocardial infarction. RTN3 knockout alleviated cardiac dysfunction after MI, while overexpression decreased systolic function.
Researchers found that accelerated aging biology in the placenta contributes to peripartum cardiomyopathy (PPCM), a rare form of pregnancy-related heart failure. The study identifies underlying aging-related biology contributing to maternal heart failure and provides evidence from both patients and animal models.
Scientists at CNIC have identified mechanisms by which anthracyclines damage the hearts of cancer patients, leading to cardiac injury. The study suggests that a protein-enriched diet may prevent muscle atrophy caused by anthracycline chemotherapy.
Over five RSV seasons, researchers found that nearly one-quarter of hospitalized adults aged 50+ experienced an acute cardiac event, mostly heart failure. The risk of severe outcomes was nearly twice as high in patients with cardiac events compared to those without.
The article discusses the evolving role of transcatheter tricuspid valve edge-to-edge repair in treating severe tricuspid regurgitation. Preliminary results show promising outcomes, making it a feasible and effective option for high-risk surgical patients.
Dr. Himabindu Vidula will lead the American College of Cardiology's (ACC) Board of Governors for a one-year term, focusing on membership engagement and community outreach. Her goal is to strengthen how the ACC serves its members and the broader cardiovascular care community.
Researchers developed a new method to detect heart failure using smartphones by analyzing heart movement. The technology has been shown to be accurate in identifying patients with heart failure, offering potential benefits for remote monitoring and treatment.
A new study found that high-dose influenza vaccine significantly improved humoral response in patients with heart failure or prior myocardial infarction. Vaccination remains crucial in preventing influenza-related complications in high-risk populations.
A meta-analysis of 11 trials involving 78,607 patients found a 9% reduction in major adverse cardiovascular events (MACE) and a 14% reduction in cardiovascular death with SGLT2 inhibitors. The analysis showed consistent effects across patient groups and subgroups.
A new study found that inter-atrial shunts improve symptoms and outcomes in heart failure patients with reduced left ventricular ejection fraction (LVEF), but worsen outcomes in those with preserved LVEF. The device reduces high pressures in the left atrium, causing shortness of breath and hospitalizations.
New York Valves: The Structural Heart Summit is a world-class educational experience for the field of structural heart interventions. The summit will showcase advanced techniques, evidence-based medicine, and live-case demonstrations, offering attendees an unparalleled opportunity to explore the newest techniques and technologies.
Two anti-inflammatory molecules, TGFβ1 and HpTGM, reduce the inflammatory response within the injured heart and scarring. Treatment with these proteins at the time of reperfusion reduces infarct size and mature scar size.
Among a sample of over 3,100 people with heart disease, 89% consumed more than the recommended daily maximum of 1,500 mg of sodium, and study participants on average consumed more than twice this amount. Limiting sodium intake is crucial for reducing major adverse cardiovascular events.
People who use e-cigarettes are significantly more likely to develop heart failure compared with those who have never used them. The study found a substantial association between e-cigarette use and an increased risk of heart failure, especially for heart failure with preserved ejection fraction.
University of Virginia researchers have identified a single gene on the Y chromosome that can account for the disease-promoting effects of Y chromosome loss. This discovery provides new avenues for understanding the causes of heart disease and could lead to a treatment for men with Y chromosome loss.
A multi-institutional team is creating innovative technologies to reduce complications associated with left ventricular assist devices (LVADs), including infection, thrombosis, stroke, and bleeding. The new LVAD will deliver a physiological response to changes in the recipient's activity levels using a 'smart' Maglev drive technology.
Research highlights treating anxiety and depression in people with heart disease can significantly reduce emergency room visits, hospitalizations, and even death. The study found that talk therapy and antidepressant medications improved heart outcomes among those with blocked arteries or heart failure.
Research found that certain patterns of pregnancy history, including early deliveries and multiple hypertensive disorders, are associated with high risk of heart attack and stroke. Others with fewer or no complications have lower risk, suggesting other factors may also play a role in predicting cardiovascular disease mortality.
Researchers found that Black individuals carrying genetic variants in the Titin, TTN gene have a high risk of developing atrial fibrillation, heart failure, and dilated cardiomyopathy. The study used data from the All of Us Research Program to examine the role of these genetic mutations in African ancestry individuals.
A multicenter randomized trial showed a paclitaxel-coated balloon to be superior to an uncoated balloon in preventing target lesion failure in patients with coronary in-stent restenosis. The study included 600 patients and demonstrated the effectiveness of paclitaxel-coated balloons as a treatment option.
Researchers at the University of Virginia Health System are developing a technique to 'paint' tiny nanoparticles on transplanted veins to prevent blockages, potentially sparing patients from repeated surgeries. This approach could significantly reduce the number of vascular reconstructions performed annually in the US.
Researchers aim to address LVAD shortcomings, reducing blood damage and clotting risk through innovative designs and coatings. A novel flexible stented blood inlet and slippery hydrophilic coatings will be used to prevent flow stasis and clot formation.
Long-term childhood cancer survivors face a significantly higher risk of death from heart-related events compared to the general public. Dyslipidemia and hypertension are key risk factors that should be treated earlier, with statins potentially providing increased protection.
A new study found that living close to pubs, bars, and fast-food restaurants is associated with a higher risk of heart failure. The study, which analyzed data from over 500,000 adults in the UK, also found that proximity and density of ready-to-eat food outlets were linked to an elevated risk of heart failure.
The REHAB-HFpEF study, led by Dalane Kitzman, aims to reduce rehospitalizations and mortality in older patients with HFpEF. A novel physical rehabilitation intervention is being tested at Advocate Christ Medical Center in Chicago.
Researchers found that pulse oximeters underestimate blood pumping and overestimate resistance, affecting treatment decisions. Direct blood oxygen measurement is crucial for accurate guidance, especially for Black patients already at higher risk.
A new study found that severe maternal grief, particularly the loss of a partner or child, is associated with an increased risk of heart failure in children up to middle age. The research suggests that prenatal stress may lead to adverse changes in mental and physical health, impacting fetal heart development.
A new study published in JAMA Cardiology found that taking 3,600 steps per day is associated with a 26% lower risk of developing heart failure. The study also found that accumulating more light and moderate intensity daily activities can help prevent heart failure.
A new study found that chronic exposure to PM2.5 is associated with increased risk of hospital admission for various cardiovascular conditions, particularly ischemic heart disease and cerebrovascular disease. The study suggests that lowering annual average PM2.5 levels could decrease overall cardiovascular hospitalizations by 15%.
Researchers at Hokkaido University developed a technique to promote cardiac regeneration by activating mitochondrial function in transplanted cells. The study found that activated mitochondria improved cardiac function and suppressed myocardial fibrosis, suggesting a new approach for treating severe heart failure.
The study of 5,951 women aged 63 to 99 found that higher levels of physical activity and lower amounts of sedentary time were associated with reduced heart failure risk. Promoting regular physical activity and limiting sedentary time may be a prudent strategy for primary prevention of heart failure in older women.
A major new study reveals that heart attack survivors are at high risk of developing further serious health conditions, including heart failure, kidney disease, and depression. The research found that up to a third of patients developed heart or kidney failure, and 38% died within nine years.
Researchers developed a test to predict which heart attack patients are likely to experience dysfunction after receiving mechanical pumps. The test measures pulmonary vascular compliance and its adaptability, helping doctors prevent right ventricle failure.
A study published in Nature Cardiovascular Research reveals that a dynamic synergy between cell types facilitates cardiac renewal, challenging existing paradigms. Targeting the microenvironment rather than specific cell types is key to healing injured hearts.
Researchers at Baylor College of Medicine have developed a gene therapy that induces heart cell proliferation and improves cardiac function in an animal model of advanced heart failure. The treatment also shows promise in improving liver and kidney functionality.
A new approach has improved heart failure outcomes in an animal model by targeting ERR-alpha receptors. The treatment, called SLU-PP-332 and SLU-PP-915, boosted the metabolism to match the hypertrophy providing enough energy for the heart to sustain the extra activity.
Researchers developed a risk calculator to predict individualized risk of right heart failure after left heart pump surgery, tailoring care to each patient. The STOP-RVF calculator uses machine learning and considers variables such as pre-existing health conditions, medications, and demographic information.
A new tool, developed with a machine learning-based approach, can predict diuretic response in patients with ADHF. The BAN-ADHF score may lead to personalized strategies for effectively managing congestion in hospitalized patients.
A comparative effectiveness trial found that behavioral activation psychotherapy and antidepressant medication management significantly reduced depressive symptoms in patients with heart failure. Psychotherapy recipients experienced better physical health-related quality of life and fewer hospital visits.
A phase 3 trial has shown that the novel drug acoramidis achieves near-complete stabilization of TTR proteins, slowing or halting disease progression. The treatment reduced hospitalizations for heart-related events and increased distance walked over six minutes.
A systematic review of 95 studies found that 3D camera system estimates, patient self-estimates, and the Lorenz method are accurate for estimating adult body weight. However, no method is foolproof, and alternative strategies should be available when patients are unable to provide an estimate.
Researchers found that impaired autophagy can lead to cardiac dysfunction by depleting NAD+ levels, which activates a chain of events causing mitochondrial and cardiac damage. Inhibiting a key enzyme in this pathway may offer new therapeutic options for heart failure treatment.
A national study by Mass General Brigham researchers found that patients treated at home had a 0.5% mortality rate, compared to those in traditional hospitals. Home hospital care also resulted in fewer readmissions and adverse events, with consistent outcomes across diverse demographic groups.
A new study by UCL researchers suggests that a vest mapping the heart's electrical activity could help identify people at high risk of sudden cardiac death. The electrocardiographic imaging (ECGI) vest combines signals with MRI images to generate 3D models, potentially predicting risk factors for life-threatening heart rhythms.
A study found that the common drug Entresto (sacubitril/valsartan) increases plasma Aβ42 and Aβ40 levels in patients with cardiac failure, making them falsely positive on a debated Alzheimer's blood test. This could lead to misclassification of patients as having Alzheimer's disease.
Patients with lower socioeconomic status in their neighborhoods have a higher risk of nonadherence to guideline-directed medical therapy for heart failure. Neighborhood-level socioeconomic factors play a significant role in shaping healthcare outcomes.
A new study by NYU Langone Health found that patients from lower socioeconomic areas were less likely to fill their heart-failure medications, highlighting the importance of neighborhood-level interventions to improve access to lifesaving drugs. The research team plans to explore additional barriers, such as cost and language barriers,...
A clinical trial found that stem cell-based therapy reduced daily hardship and improved physical and emotional health in patients with advanced heart failure. Patients who received the treatment had lower death and hospitalization rates compared to those on standard care.
Researchers have developed an AI-powered algorithm that can detect the risk of atrial fibrillation (AFib) with high accuracy, even in people with infrequent AFib episodes. This new tool has the potential to reduce the incidence of stroke and heart failure by identifying patients at increased risk and guiding targeted interventions.
A randomized clinical trial found that excluding aspirin from the antithrombotic regimen in LVAD patients improved adverse event rates by a significant reduction in non-surgical bleeding. The study results suggest that an aspirin-free regimen is safe and may improve longevity, morbidity, and quality of life for these patients.
Adults with congenital heart disease are at increased risk of death or cardiovascular complications after hospitalization for heart failure. However, those who received recent cardiology care before hospital admission had lower rates of death and major complications.
A study published in Med suggests that low-dose radiation therapy can improve heart function by reducing inflammatory immune cells and scar tissue in the heart. Researchers found improved pumping capacity and increased survival of mice with heart failure after receiving radiation therapy.
Despite its cost-effective prevention for recurrent events, cardiac rehabilitation remains inaccessible to many due to lack of social support, particularly in poorer countries. Home-based rehabilitation and comprehensive lifelong healthy behavioral programs may help address these barriers.
Thirty-two institutions earned the SET-10 distinction, with top ten recognized globally for their dedication to advancing scientific knowledge in interventional cardiovascular medicine. The rankings span six categories and acknowledge excellence within and outside the United States.
A groundbreaking study published in JAMA found that excluding aspirin from the antithrombotic regimen for patients with a fully magnetically levitated left ventricular assist device (LVAD) resulted in a significant decrease in major nonsurgical bleeding events. This approach is safe and beneficial, challenging conventional practice and...
Adults with lower household incomes are less likely to receive cardiologist involvement during heart failure hospitalizations. Socioeconomic factors may influence the quality of care provided to these patients.
Researchers found that removing aspirin from treatment while continuing vitamin-k antagonists in patients with modern left ventricular assist devices (LVADs) did not increase clotting-related risks or pump malfunctions. Aspirin avoidance was associated with a reduction in bleeding events, lower hospital days, and decreased cost of care.