Articles tagged with Obesity
A recent study found that maternal obesity and excessive pregnancy weight gain significantly increased the risk of childhood obesity by age 3. Researchers tracked nearly 3,000 mother-child pairs and discovered that excess pregnancy weight gain was common, affecting about four in 10 mothers.
A systematic review and network meta-analysis found that combining lifestyle treatment with obesity medications resulted in significant short-term weight loss and improved body composition in adolescents. Health behavior remained crucial to effective weight management.
Research reveals genetic variations linked to obesity are more strongly associated with high BMI in younger generations, suggesting a stronger link between genetics and environment
Researchers at the University of Zurich have developed epigenetic drugs that can reprogram perivascular fat cells to reduce inflammation and improve blood vessel health. By targeting specific gene-expression regulators, these drugs aim to prevent vascular damage in people with obesity and metabolic disease.
New research found that GLP-1 RA users showed weaker associations between impulsivity and violent crime, suggesting these medications may lessen risk factors. The study analyzed data from a US survey of adults who used GLP-1 medications.
The AGA commentary updates the POWER framework to reflect major advances in obesity care, including effective anti-obesity medications and bariatric surgery. Gastroenterologists play a crucial role in obesity management, caring for patients with related conditions.
A survey of over 5,700 Chinese adolescents found significant associations between screen time, body weight, and mental health with sleep quality. Rural adolescents and girls fared worse overall, highlighting the need to address these factors to improve sleep.
Research suggests GLP-1 receptor agonists modulate immune responses and reduce inflammation in skin diseases. Studies indicate improvements in psoriasis severity indices following treatment with these drugs.
A study found that prebiotic xylo-oligosaccharides reduced harmful metabolites and improved liver health in overweight adults. The composition of the gut microbiota prior to supplementation influenced the benefits observed.
A cohort study found that demographic, clinical, and healthcare factors influence the uptake of metabolic bariatric surgery among US adults with obesity. The study suggests improving access to this life-changing procedure through targeted policies and interventions could have a significant impact.
A study found that tirzepatide significantly increases brown adipose tissue activity and volume in premenopausal women with obesity. The medication also shows potential signs of converting white subcutaneous fat into more metabolically active 'beige' fat.
A new study investigates whether obesity contributes to faster brain aging and earlier memory decline. Researchers found that high K63 polyubiquitination levels in young obese rats matched those seen in older brains, suggesting a connection between obesity-induced and age-related memory loss.
A new study reveals that obesity is reshaping the global cardiovascular disease crisis, with heart disease now peaking in people aged 50-54 rather than the elderly. The study projects over 1.37 million premature cardiovascular deaths attributed to obesity by 2050, primarily in South Asia and low-income countries.
The American College of Physicians recommends semaglutide and tirzepatide as first-line treatments for nonpregnant adults with obesity, while recommending lifestyle modifications including improved nutrition and physical activity. The guideline also emphasizes discussing benefits, harms, costs, and contraindications with patients.
Clinical trials suggest that GLP-1s can improve testosterone levels and sperm quality in men with obesity-related low testosterone. The research also found that GLP-1s address the underlying effects of obesity on fertility. The studies showed no negative impact on hormones, sexual function, or sperm quality.
A new study from Ann & Robert H. Lurie Children's Hospital of Chicago found that metabolic and bariatric surgery for teens with severe obesity is a cost-effective option over 10 years. The procedure sends type 2 diabetes into remission, sparing patients years of medication and complications.
A recent study found that women and individuals with minimal motivation to lose weight experienced greater weight loss on tirzepatide. The research also identified baseline clinical, demographic, and behavioral variables associated with weight loss trajectories over 12 months.
A study found that nearly 4 in 10 patients stopped GLP-1 medication within the first year and nearly two-thirds restarted therapy within two years. The researchers also identified sociodemographic, clinical, and provider-level predictors of discontinuation, including Medicaid or Medicare status, Black patients, and side effects.
A study presented at ENDO 2026 found semaglutide was associated with a 15% reduction in bone fractures and greater weight loss compared to other anti-obesity medications. The results suggest that semaglutide may have beneficial effects on bone health in people with type 2 diabetes.
A study found that adults taking GLP-1 receptor agonist medications experienced significant decreases in daily step counts and moderate-to-vigorous physical activity, highlighting the need for targeted interventions to promote exercise alongside obesity treatment.
A recent study of 42,000 adults taking blood pressure medications and GLP-1s found higher rates of hypotension events, including dizziness and fainting. The study highlights a potential safety concern for patients aged 65 and older and those with diabetes.
A study published in The Lancet found that Chile's comprehensive food policies, including labelling and advertising bans, have a real-world impact on reducing child obesity. After implementing the Food Labelling and Advertising Law in 2016, children who had been at school for 18 months showed a lower risk of overweight or obesity compa...
The American Society for Nutrition (ASN) and The Obesity Society (TOS) have formed a strategic alliance to accelerate progress in both fields. This collaboration will drive evidence-based solutions that shape practice, inform policy, and improve health outcomes worldwide.
A new study by Pennington Biomedical and collaborators found that Americans with the highest levels of obesity are undergoing fewer surgical procedures overall. Despite the increasing prevalence of extreme obesity, these individuals appear to be receiving proportionally fewer surgical interventions each year. The research highlights gr...
A cohort study found that smartphone acquisition at age 13 was linked to increased risk of insufficient sleep at age 14. Excessive smartphone use was also tied to higher odds of depression and obesity. Limiting screen time may protect adolescents from these outcomes.
A study analyzing insurance claims data found similar risks between continued and non-continued GLP-1RA medication use during early pregnancy. The authors conclude that further research is needed to better understand the safety of GLP-1RAs in pregnancy due to imprecise estimates for rare outcomes.
Mazdutide, a GLP-1 receptor dual agonist, provides clinically meaningful weight reduction in Chinese adults with obesity. However, gastrointestinal adverse reactions are more common among those taking the drug compared to placebo.
A study of over 229,000 obese adults without diabetes found that weight loss drugs, such as semaglutide and tirzepatide, were associated with a 41% decrease in the overall risk of developing obesity-related cancers. GLP-1 RAs also showed larger reductions in certain subgroups, including men and gynaecologic cancers.
Adults with both obesity and an autoimmune disease who took a GLP-1-based medication had fewer emergency department visits and lower mortality rates compared to those not taking the medication. The study analyzed data from over 26,000 adults treated in the OneFlorida+ network between 2014 and 2024.
A new study reveals how Philip Morris Companies Inc. used cigarette research and flavor engineering to design Lunchables, a successful ultra-processed food for children. The company's strategy was based on optimizing 'technical synergies' between tobacco and food divisions.
Researchers from Pennington Biomedical will showcase their latest findings on prevention, care, and cures for diabetes and obesity at the American Diabetes Association's 2026 Scientific Sessions. The sessions will highlight cutting-edge advancements driving progress in diabetes research and management.
The University of Texas at San Antonio has received significant funding from the Cancer Prevention and Research Institute of Texas to develop innovative cancer research technologies and treatments. The institution will focus on pressing cancers such as Ewing sarcoma, obesity-related endometrial cancer risk, and AI in clinical oncology.
Researchers at Pennington Biomedical published the first study to estimate pediatric obesity prevalence among US children and adolescents aged 5-18 years using the new Lancet Commission definitions. The study found that many children are already experiencing measurable health impairments associated with obesity.
The use of weight loss medications like semaglutide and tirzepatide could deepen existing health inequalities if patients lack access to nutrition advice, healthy food, and ongoing healthcare support. Researchers warn that poorer patients may face barriers to using these treatments safely and maintaining health improvements over time.
Researchers highlight latest developments in pathology, diagnosis, and treatment of MASLD and IPFD, revealing correlations with chronic diseases like liver cancer and pancreatic cancer. Innovative treatments, such as AI-driven approaches and organ-targeted therapies, show promise for precision prevention and therapy.
Weight loss after bariatric surgery is associated with better ability to cope with daily household tasks such as cleaning and grocery shopping. The study also found that maintaining weight loss for long periods results in improved functionality and independence. Patients who regained lost weight experienced poorer outcomes over time.
A study found that BMI significantly understates obesity levels in the US, with up to 50% of overweight individuals reclassified as obese under a new clinical definition. This highlights the need for healthcare providers to adopt this new measure to better identify and treat obesity-related health risks.
A new study found that nearly a quarter of adults with a normal weight BMI may still be at risk for obesity-related health complications. The research highlights the importance of considering multiple factors beyond body mass index (BMI) to accurately identify individuals at risk for these conditions.
Two new international studies found that healthy lifestyles can have a protective effect on childhood cancer survivors, reducing the risk of chronic health problems. The studies suggest that physical activity, a healthy weight, and other lifestyle factors can significantly reduce the burden of disease in adulthood.
Researchers found that obesity alters the biological changes in breast cancer cells, enabling them to survive and thrive. The study's findings could improve prediction and treatment of invasive breast cancer, reducing overtreatment and unnecessary treatments.
A new study found that drinking tomato-soy juice lowered pro-inflammatory proteins in healthy adults with obesity after four weeks. The findings hint at the juice's promise as a functional food that may help curb chronic inflammation and improve health outcomes for patients with pancreatitis.
Two studies suggest that weight loss after bariatric surgery reduces cancer risk in women, with insulin levels and genetic background playing key roles. Women carrying a specific FTO genetic variant showed significant breast cancer risk reduction.
A new study published in Nature Medicine finds that semaglutide improves weight loss and metabolic health outcomes in patients who do not respond well to bariatric surgery. Patients taking semaglutide showed significant weight loss from body fat, improved blood sugar levels, and better quality of life.
A new study reveals that metabolic dysfunction in offspring is caused by excess microRNA in sperm from obese fathers. After weight loss, these molecular marks disappear, and offspring develop normally. Research suggests that interventions promoting health and longevity may trigger an increase in this enzyme expression.
A low-calorie diet and behavioral support program significantly reduced weight in older patients with overweight and persistent atrial fibrillation at 8 months. The study found no safety concerns or impact on atrial fibrillation symptoms, cardiac remodeling, or need for further rhythm control interventions.
Researchers developed an AI framework, MouseMapper, to map disease-related changes in the entire mouse body. They found widespread inflammation and previously unrecognized damage to facial sensory nerves caused by obesity, which was also observed in human tissue.
Researchers identified a subgroup of patients who experience nearly twice the improvement in sleep apnea when treated with tirzepatide GLP-1. These strong responders have distinct characteristics, including severe upper-airway collapsibility and breathing control instability. The study aims to provide personalized treatment options for...
A new study published in eBioMedicine found that integrating measurements such as body fat percentage and waist circumference can help identify individuals at high risk of developing obesity-related diseases. The research team analysed data from 489,311 participants and found that those with an adverse adiposity profile despite normal ...
A research study, COACH trial, is testing different ways to help children and families improve their health through lifestyle changes delivered by primary care clinics. The study aims to assess the effectiveness of personalized nutrition counseling, community resources, and online interactive lessons on weight management.
Weight loss followed by weight regain, known as 'yo-yo dieting,' is not supported by strong scientific evidence. The authors found that benefits of losing weight outweigh the theoretical risks of weight cycling in most cases. Repeated attempts at weight loss can provide meaningful periods of improved metabolic health and quality of life.
The European Association for the Study of Obesity, dietitian societies, and patients' organizations have issued a new consensus statement on using incretin drugs to treat obesity. The statement highlights the importance of medical nutritional therapy (MNT) and reinforces healthy dietary patterns. It also emphasizes the need to monitor ...
A comparative study found that endoscopic sleeve gastroplasty (ESG) is associated with significantly greater short-term weight loss than oral semaglutide. Patients undergoing ESG achieved a mean total body weight loss of 12.7%, compared to 8.7% in those receiving semaglutide.
A nationwide self-controlled cohort study found that GLP-1 class of obesity drugs were associated with a 26% fall in asthma exacerbations and a 14% drop in use of asthma inhaler reliever. The study suggests that weight loss, modulation of airway inflammation, and improvements in metabolic functions may improve asthma outcomes.
A meta-analysis of 32 studies and 43,618 adults found a clinically relevant drop in blood pressure with obesity drugs for weight loss. The study shows that GLP-1RAs and MHRMs can induce significant BP reductions, with a 0.34 mmHg reduction per 1% weight loss.
A new study published at the European Congress on Obesity found that participants who underwent rapid weight loss lost significantly more weight than those who followed a gradual weight loss plan. After one year, the rapid weight loss group had achieved clinically meaningful weight loss and maintained it better than the gradual weight ...
A nationwide study in Denmark shows a 7% reduction in triptan use for migraine treatment among women taking semaglutide for weight loss, with no significant change observed among men. The study suggests that weight loss and potential direct effects of GLP-1RA treatments may contribute to reduced migraine medication use.
Two scientists, Dr. Anna Elizabeth Thalacker-Mercer and Dr. Rachel Whooten, receive awards for their groundbreaking research on micronutrients and muscle health in relation to aging and disease, as well as innovative approaches to childhood obesity care.
Research reveals bidirectional relationships between higher BMI and financial difficulties, loneliness and stress. Higher BMI may lead to stigma, social isolation and healthcare costs, while financial strain can limit access to healthy food and physical activity.
The article discusses how studying art history can aid in treating obesity, highlighting its long-standing depiction as a sign of prosperity and physical strength. Doctors can become more empathetic towards patients by understanding this historical context.
A new study suggests that GLP-1 receptor agonists and GIP/GLP-1 receptor agonists can lead to substantial fat loss while preserving skeletal muscle mass in relative terms. The study found that muscle mass remained stable over time when accounting for changes in fat mass.