Articles tagged with Obesity
A new study found a strong association between social determinants of health and obesity rates, with higher SDOH burden leading to increased obesity prevalence. The study analyzed data from nearly 165,000 adults in the US and found that middle-aged and non-Hispanic Black adults were more likely to be overweight or obese.
Researchers at Boston Children's Hospital have developed an organoid platform that identifies drugs that enhance enteroendocrine cell action, potentially reversing diabetes, obesity and gastrointestinal conditions. The system identified three chemicals that drive the formation of EE cells and hormone production.
Research found that over 55,000 chemicals in everyday plastic products can reprogram precursor cells to become fat cells, leading to increased fat accumulation. The study suggests that previously unknown plastic chemicals may be contributing to overweight and obesity.
Scientists at Nanyang Technological University have developed a novel therapeutic approach to tackle obesity, reducing body fat and improving blood markers through a hydrogel injection and near infrared light treatment. The treatment shows significant promise in lab trials, with mice experiencing reduced body mass and improved metabolism.
A new Penn State study found that Black youth with high BMIs reported fewer weight concerns when they had a strong sense of racial identity. Fathers also played a role in shaping their daughters' body image, particularly when involved in teaching about Black culture. The findings suggest that services promoting youth racial identity an...
Researchers found that some people's genes determine whether they store fat in a 'favourable' or 'unfavourable' way, affecting their risk of diseases. Even those with 'favourable adiposity' are still at risk for certain health issues.
A new study found that living in a disadvantaged neighbourhood increases a child's risk of developing overweight by school age. Children born in less affluent areas were more likely to gain weight and develop obesity, even when controlling for other factors.
A recent study published in Drug and Alcohol Dependence found that people with underweight who drink excessively may be at an even higher risk of dying from heart disease, cancer, and other causes. The researchers analyzed data on mortality risk among drinkers and non-drinkers using the CDC categories to define
A new federally funded study will use machine learning to create a first-of-its-kind algorithm predicting individual responses to food and dietary routines. The National Institutes of Health's All of Us Research Program will recruit 10,000 participants nationwide.
Researchers discovered that Black women have a greater relative abundance of Actinobacteria, associated with reduced insulin sensitivity and elevated inflammation. The study highlights the importance of understanding the role of gut microbiome in cardiometabolic health disparities among Black women.
A nationwide study found that weight loss prior to starting infertility treatments did not increase the chances of having a healthy baby. Women with obesity and unexplained infertility who lost weight before beginning therapy did not have a greater chance of delivering a healthy baby than those who did not lose weight.
A comprehensive study of exercise performed at different times of the day has identified distinct health-promoting signaling molecules produced by the body in an organ-specific manner. The findings suggest that exercising at the right time can optimize health benefits, particularly for individuals at risk of obesity and type 2 diabetes.
A recent study published in Scientific Reports found that chewing food thoroughly increases energy expenditure through diet-induced thermogenesis (DIT), which helps prevent obesity. The study involved participants who chewed liquid food for varying durations, revealing that prolonged chewing and tasting increased DIT, gas exchange, pro...
A new study has identified 74 previously unknown genomic regions that influence how people's bodies break down food into energy. These findings could help develop more personalized ways to maintain a healthy weight by taking into account an individual's genetic profile.
Researchers at Penn State developed a new risk score system that uses genetic data to predict obesity in young children. The scores, called polygenic risk scores, can be easily interpreted and have been shown to be effective in identifying children most at risk for developing obesity.
Aspirin use in primary prevention of cardiovascular disease should be individualized based on benefit-to-risk assessment, not age. The authors' updated meta-analysis shows a 13% reduction in cardiovascular disease with similar benefits at older ages.
A new interdisciplinary treatment method has shown significant improvements in reducing overeating episodes and emotional issues among individuals with morbid obesity. The treatment combined mental health care with somatics, resulting in a nearly 30% reduction in overeating episodes and improved emotional well-being.
A systematic review of 26 studies found that the British food environment hinders weight loss efforts and maintains obesity. Policymakers are advised to address this issue through effective policy changes to create a healthier food environment.
A Cleveland Clinic study found that prior weight loss achieved with bariatric surgery was associated with a 60% lower risk of developing severe COVID-19. Patients who underwent weight-loss surgery had better clinical outcomes, including reduced hospitalization and need for supplemental oxygen.
A study conducted at the University of Turku found that following a healthy diet in early pregnancy can significantly reduce the risk of developing gestational diabetes. The research revealed that a diet high in saturated fats and low in essential nutrients increases inflammation and raises the risk of gestational diabetes.
A study of nearly 12,000 obese patients found that substantial weight loss achieved through weight loss surgery was associated with improved outcomes after contracting COVID-19, including lower risk of severe disease. The results suggest that weight loss surgery may help mitigate the severity of COVID-19 in individuals with obesity.
A study by Kanazawa University researchers found that the chemokine CCL3 plays a significant role in inducing inflammation as nonalcoholic fatty liver disease develops. The presence of CCL3 increased liver macrophage accumulation, leading to liver inflammation and scarring.
A global study found that hospitalized COVID-19 patients with metabolic syndrome had a 20% higher risk of developing acute respiratory distress syndrome (ARDS) and dying. The study examined records of over 46,000 patients in 181 hospitals across 26 countries.
A new Northwestern University study has derived and validated the first set of risk prediction models for lifetime risk of heart failure. The models can identify individuals at greatest risk, especially among young adults, allowing physicians to start prevention measures sooner.
A study analyzing McDonald's social media marketing across 15 countries found that the company prioritizes children in lower-middle-income countries with more posts and child-friendly content. This may exacerbate existing healthcare issues in these vulnerable populations.
A new study found that news media amplified rather than rectified misleading health information from TV personality Dr. Oz, resulting in the further spread of misinformation. The researchers called for government oversight to lessen the risk of spreading inaccuracies.
Researchers found that SGLT2 inhibitor empagliflozin can improve insulin sensitivity in the brain, leading to better glucose control and reduced liver fat content. This breakthrough discovery positions SGLT2 inhibitors as a potential treatment for insulin resistance in the brain.
Researchers at UC Davis Health developed a new treatment that simultaneously blocks IL-6 and TNF cytokines, providing superior protection against acute graft-versus-host-disease severity and mortality. The dual-cytokine blockade approach did not impair beneficial graft-versus-tumor effects.
Research shows autistic adults on Medicaid have higher odds of co-occurring physical and mental health conditions, including diabetes, obesity, and epilepsy, compared to the general population. Racial and ethnic disparities are also evident, with Black, Hispanic, and Asian adults facing higher odds of certain conditions.
A study in mice suggests that transplanted brown fat can reduce type 2 diabetes risk factors after a heart attack by dampening gene activation linked to negative effects. The transplantation method could help researchers understand the mechanisms behind this protective effect and potentially lead to therapeutic applications.
Scientists have developed a new method using CRISPR-Cas9 to target specific fat cells, reducing the time and cost of genetic discovery in obesity research. The technique allows researchers to study genes in brown adipose tissue, which plays a crucial role in regulating body temperature.
A new research project, SYSTAM CHINA-SEACS, aims to develop systemic solutions to tackle both undernutrition and overweight, obesity or diet-related NCDs. The study will be piloted in the Chinese city of Fang Cheng Gang and has the potential to improve the health and living conditions of billions of people.
Researchers found that flavanols activate brown adipose tissue, causing it to burn calories and produce heat. Long-term consumption of flavanols increased the levels of heat-related proteins in mice, suggesting a potential therapeutic effect against obesity-related diseases.
Metabolic disorders, such as inflammation and insulin resistance, are key elements in the development of anxiodepressive disorders in obese individuals. Diet high in sugar and saturated fats leads to these changes in the brain, increasing the risk of depression and anxiety.
A study by University of New South Wales has found that one in five future thyroid cancers in Australia is attributable to current levels of overweight and obesity. The prevalence of obesity has doubled in the last two decades, with 75% of Australian men and 60% of women being overweight or obese.
A study found that obesity is associated with severe COVID-19 outcomes, including hospital admission or death. Additionally, accelerated immunosenescence may be a key mechanism explaining the relationship between obesity and T2DM in severe COVID-19. Vaccination effectiveness may also be impacted by metabolic disorders.
A University of Gothenburg study found that bariatric surgery lowers cancer risk by 60% in obese patients with type 2 diabetes, particularly those achieving and maintaining normal glucose control. The research highlights the importance of glucose control in preventing cancer in this high-risk population.
A study by the CDC found a strong association between obesity and diabetes, both of which are widespread in the U.S., and severe COVID-19 disease. In South Carolina, chronic diseases disproportionately affect Black communities, increasing their risk of developing severe COVID-19.
Researchers found that high avocado consumption led to reduced caloric energy intake, lower dairy and meat consumption, and improved fiber and nutrient intake. However, unexpected decreases in calcium and certain minerals were also observed.
Researchers at HKU have identified a naturally occurring flavone as a potential drug for obesity treatment. The study found that obesity damages skeletal muscle metabolism by reducing brain-derived neurotrophic factor (BDNF) levels, leading to impaired mitochondrial function and insulin resistance.
Researchers found that video-based, telehealth-delivered exercise and weight loss programs improved pain and function in people with knee osteoarthritis and overweight or obesity. The intervention with dietary component led to substantial weight loss and additional benefits.
Researchers at UConn Health have discovered that eliminating senescent cells in human fat tissue can alleviate signs of diabetes and improve insulin sensitivity. The study suggests that clearing away these dysfunctional cells could lead to game-changing new treatments for Type 2 diabetes.
Researchers from the University of Tsukuba found that lifestyle factors such as smoking, alcohol consumption, and sedentary behavior significantly increase the risk of developing metabolic syndrome in non-obese individuals. Similar risk factors were identified for both obese and lean individuals, highlighting the importance of healthy ...
Researchers have discovered a protein called CPEB4 that plays a key role in diet-induced obesity. Blocking CPEB4 expression in mice protected them from weight gain, inflammation, and improved their microbiome health. The findings could lead to new treatments for diet-induced obesity and its associated cancer risks.
A clinical trial found that long-term weight loss was similar for those who received 5:2 diet or standard weight management advice, with 18% and 15% of participants losing at least five per cent of their body weight. However, the 5:2 diet group was more likely to recommend the intervention to others or continue with it.
A research team has identified a subset of cerebellar neurons that signal satiation after eating, leading to reduced food intake in mice. The findings suggest a novel target for therapies that could curb overeating and obesity.
Research suggests that using mirrors can decrease anxiety and body dissatisfaction in individuals with obesity. This mirror-based intervention aims to promote self-assessment and reflection, leading to behavioral changes.
A recent study analyzed over 18,000 reported adverse events from patients taking various anti-obesity medications. The study found that 4.9% of reported events were fatal, with 35% requiring hospitalization. Further research and monitoring are needed to address the safety concerns surrounding these medications.
A study analyzing data from 109 COVID-19 patients found that obesity is the key factor associated with endothelial dysfunction, a condition increasing heart attack and stroke risk. The results suggest an 17% higher cardiovascular risk for obese patients compared to those of normal weight.
Research suggests that obesity triggers inflammation, leading to an increase in myeloid-derived suppressor cells, which break down bone tissue. This can result in gum disease and tooth loss. The study found a significant link between high-fat diets and increased osteoclasts and alveolar bone destruction.
A study by West Virginia University researcher Sunil Sharma found that rural COVID patients who end up in an intensive care unit are more likely to die within 30 days compared to their urban counterparts. The researchers also discovered that rural patients with COVID-linked ARDS have a higher mortality rate, even when controlling for d...
A major Finnish–Norwegian study found that obesity does not lower the risk of subarachnoid haemorrhage, as smoking habits are a significant factor in the condition. The study analyzed over 200,000 individuals and comprehensively considered confounding factors.
A Johns Hopkins-led study found that leptin cancels out the effects of Tamoxifen, making it ineffective for obese patients with breast cancer. Researchers suggest that interventions targeting leptin or Med1 may improve Tamoxifen's success in this group.
Research suggests COVID-19 pandemic has adverse effects on women's menstrual cycles due to stress and sleep disturbance. Women are experiencing increased rates of depression, anxiety, and poor sleep.
A new study identifies four novel obesity genes and predicts a fifth, using a platform of fat fruit flies. The research found that these genes are involved in a neuronal signaling pathway that increases fat levels.
An 8-country study finds that obesity will contribute 3.6% of a nation's GDP by 2060, with total costs projected to double in Spain and increase 19-fold in India. Reducing obesity prevalence could cut average annual costs by 5-13%.
A study found that cardiopulmonary exercise testing is highly applicable for early detection of respiratory disorders in obese individuals. The test assesses physiological responses to exercise and identifies potential issues before symptoms appear.
A study at the University of Turku found that brain function regulating satiety and appetite is altered before obesity develops, with family background risk factors contributing to these changes. The findings suggest the brain and central nervous system are key targets for treating obesity.
A study published in Nature Communications identified C-terminal binding protein 2 (CtBP2) as a global regulator of metabolism that balances sugar and fat levels in the liver. CtBP2 is crucial for controlling glucose and lipid balance, making it a promising drug target for treating symptoms associated with obesity.
Researchers found that around 5% of patients with type 2 diabetes in Scotland are in remission, suggesting a need for updated guidelines to support clinicians. Individuals in remission tend to be older and have lower blood sugar levels at diagnosis, and often achieve remission after weight loss since their diagnosis