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Antibiotic prescription patterns violate guidelines, increase costs

A study found that only 24% of antibiotics prescribed for women's urinary tract infections are the recommended drug, down from 48% in 1990. The alternative medications are no more effective and cost 11-40 times as much. This trend appears to result from non-clinical forces such as pharmaceutical promotions and sub-specialty culture.

SourceUniversity of Chicago Medical Center·JournalArchives of Internal Medicine·DateJan 13, 2002

Many seniors forced to skip prescription meds

A study found that seniors with limited insurance are more likely to restrict their prescription medication use. The practice was common among minority groups, the poor, and those with high out-of-pocket drug costs. This can lead to increased emergency department visits, nursing home admissions, and other health problems.

SourceCenter for Advancing Health·JournalJournal of General Internal Medicine·DateDec 4, 2001

NHLBI supported study finds inhaled steroids accelerate bone loss in women with asthma -- treatment still recommended for persistent asthma

A new study published in the New England Journal of Medicine found that premenopausal women using inhaled corticosteroids for persistent asthma experience accelerated bone loss in the hip compared to those not using the medication. The study suggests a potential long-term risk of hip fractures for these women.

SourceNIH/National Heart, Lung and Blood Institute·JournalNew England Journal of Medicine·DateSep 26, 2001

Increased use of prescription drugs - especially new ones - outpaces price hikes as source of cost increase

A new University of Michigan study confirms that the utilization of prescription drugs, especially newly introduced ones, is the biggest reason for double-digit increases in overall prescription drug costs. Managed care insurance plans saw a 35% jump in prescription costs due to their members' rush on existing and new drugs.

SourceMichigan Medicine - University of Michigan·JournalThe American Journal of Managed Care·DateJul 12, 2001

Drug war strategy: First fund enforcement then switch to treatment, says O.R. paper

Researchers suggest emphasizing law enforcement at early stages of a new drug epidemic, then shifting funds to treatment when use flattens. The model is based on data from the U.S. cocaine epidemic and takes into account market and price dynamics, including the role of initiation, cessation, and treatment.

Media coverage of new drugs is often misleading

A collaborative study found that media coverage of new medications tends to exaggerate their benefits, ignore their risks, and fail to disclose their costs. Only 40% of news stories citing experts with financial ties to the drug being studied disclosed this potential conflict of interest.

SourceHarvard Medical School·JournalNew England Journal of Medicine·DateMay 31, 2000

Who should have heart bypass surgery? New guidelines will help doctors, patients decide together

The new guidelines chart the rapid evolution of bypass surgery techniques and provide a framework for physicians to evaluate risks and benefits with their patients. The report categorizes heart patients into groups that predict how well bypass will work for them based on various factors.

SourceMichigan Medicine - University of Michigan·JournalJournal of the American College of Cardiology·DateSep 30, 1999

Depression-treating drugs lead record-setting pharmacy benefit cost rise -- Total increase lower when pharmacy benefit actively managed

Depression-treating drugs were the biggest contributor to a record-setting pharmacy benefit cost increase of 16.8 percent last year, according to Express Scripts. Plan sponsors who actively managed their pharmacy benefits cut the cost increase in half by encouraging the use of lower-cost but equally effective drugs.

Managed-Care Systems Could Save By Eliminating Restricted Access To Dermatologists

Two studies presented at the American Academy of Dermatology meeting suggest that primary care doctors often refer patients with skin problems to dermatologists, wasting time and resources. Dermatologists diagnose skin diseases more quickly than other doctors, saving money for both patients and healthcare systems.

SourceAtrium Health Wake Forest Baptist·JournalJournal of the American Academy of Dermatology·DateMar 19, 1999

Climate Change May Impact Waterborne Diseases

A study by Penn State economists suggests that climate change could lead to an increase in waterborne diseases like Cryptosporidiosis, which can be fatal among immunocompromised individuals. The researchers estimate that doubling the frequency of 100-year floods could add up to $70 per person in costs.

Drug Regimen Reduces Atrial Fibrillation After Heart Surgery

A study conducted at the University of Michigan Health System found that administering amiodarone prior to elective heart surgery reduced atrial fibrillation by approximately 50%. Patients who received amiodarone experienced less discomfort, shorter hospital stays, and lower hospital costs compared to those who received a placebo.

SourceUniversity of Michigan·JournalNew England Journal of Medicine·DateDec 18, 1997