Articles tagged with Human Reproduction
A new study reveals that benzyl butyl phthalate (BBP) causes oxidative stress and DNA strand breaks, leading to cell death and abnormal chromosomes in egg cells. The research suggests that BBP exposure can lead to lower quality egg cells with compromised genomic integrity.
Researchers found that chimpanzees have a similarly narrow pelvis to humans, contradicting previous theories. The study proposes a new hypothesis that the obstetrical dilemma developed gradually and became increasingly exacerbated over evolution.
US women between 20-44 years old have experienced declining vitamin A, C, and iron intake over the last two decades. This trend may have significant implications for maternal and fetal health. The study aims to identify these nutrient gaps and inform recommendations to improve intake.
A study found increased menstrual irregularities in women living in areas affected by the 2023 earthquake in Turkey. Risk factors included post-traumatic stress symptoms, chronic diseases, and smoking.
Gestational carriers, also known as pregnancy surrogates, are at a higher risk for severe maternal morbidity, hypertensive disorders of pregnancy, and postpartum hemorrhage compared to women carrying their own pregnancies. The study found that these risks were nearly twice as high as in unassisted conception pregnancies.
A groundbreaking study finds that stress-induced changes in sperm motility occur after a stressful event, not during it, and improves sperm performance. Researchers observed changes in extracellular vesicles that play a role in sperm development and maturation.
The atlas contains data for around 626,000 cells from 121 people, including individuals with and without endometriosis. Researchers found two types of immune cells and two types of stromal cells potentially involved in endometriosis, highlighting new avenues for future research.
Researchers at RIKEN Center for Biosystems Dynamics found multiple specialized types of DNA replication in early-stage embryos, including a period of instability prone to chromosomal copying errors. This discovery could lead to improved methods of in vitro fertilization (IVF) and better strategies for minimizing chromosomal abnormalities.
Researchers analyzed national Medicaid data to identify perinatal and postpartum outcomes among people with intellectual and developmental disabilities. Autistic pregnant people had significantly higher probability of postpartum anxiety and postpartum depression compared to other groups.
A new study found that living near areas where pesticides were used during the first trimester of pregnancy or pre-conception increases the risk of stillbirths. Researchers linked pesticide use records to state birth certificate data and found specific chemicals, such as organophosphates and pyrethroids, to be associated with increased...
A large-scale randomized controlled trial found no difference in live birth rates between time-lapse imaging and standard approaches used in IVF. The study suggests that time-lapse imaging does not improve clinical outcomes for women undergoing fertility treatment, contrary to theoretical benefits.
A new tool has been developed to compare gender inequality among different US states, revealing substantial gender disparities across the country. States with higher gender inequality scores tend to have lower measures of women's wellbeing and fewer tweets about the #MeToo movement.
A new study has found that gestational carriers experience a severe maternal morbidity rate of 7.1%, significantly higher than unassisted conceptions (2.4%) and IVF conceptions (4.6%). Gestational carriers are also at risk for postpartum haemorrhages and hypertensive disorders, which can be serious complications during pregnancy.
A new study has found that exposure to fine particulate matter prior to oocyte retrieval during IVF can reduce the odds of achieving a live birth by almost 40%. The research analysed 3,659 frozen embryo transfers and found that even in areas with excellent air quality, higher PM2.5 exposure was associated with decreased live birth rates.
The UK has released a pioneering Code of Practice for the use of stem cell-based embryo models in research, providing standards for rigorous ethics and maximizing benefits. The code sets out processes for decision-making in research using these models, allowing scientists to proceed confidently while maintaining public trust.
A new study found that Texas' 2021 ban on abortion in early pregnancy was associated with unexpected increases in infant and neonatal deaths in Texas between 2021 and 2022. Congenital anomalies also surged in Texas, but not elsewhere in the US.
Researchers at Dartmouth College found that fruit fly oocytes can renew chromosome-linking proteins, potentially helping older women reduce pregnancy complications. The discovery could lead to new therapeutic strategies for enhancing protein rejuvenation in human eggs.
Researchers Polina A. Loseva and Vadim N. Gladyshev challenge the existing definition of human life, suggesting a new meaning for the 14-day stage in organismal life grounded in recent mechanistic advances and insights from aging studies. This stage defines the separation of soma from the germline and marks the boundary between rejuven...
The summit aimed to improve care for people with cancer by discussing knowledge gaps, societal stigma, and shifting policies. Experts emphasized the importance of education about sexual and reproductive health in cancer treatment.
A study from Stockholm University found that the Swedish speed premium policy, introduced in 1980, led to a 26% increase in premature birth rates over six years. However, relaxation of the policy to a 30-month window resulted in an 11% decrease in premature birth rates in subsequent years.
A new study reveals insights into the human ovary's factors that enable follicles to mature, enabling potential treatments for ovarian hormone production restoration and fertility. The atlas may lead to the creation of artificial ovaries in labs using stored tissue, providing a longer fertility window for patients.
A new study found that postmenopausal women exhibit smaller cortical surface areas in certain brain regions, reduced thalamic subnuclei volumes, and decreased functional connectivity, suggesting a link between menopause-related symptoms and brain changes.
A new study led by Karolinska Institutet reveals the mechanism of sperm entry into the egg, explaining how mutations in egg coat proteins cause female infertility. The research also suggests potential implications for non-hormonal contraceptives.
Researchers found associations between prenatal vitamin and metal exposures and epigenetic aging biomarkers in early life. A one standard deviation increase in essential metals was associated with lower Horvath EAA at birth, while arsenic was linked to greater EAA at birth and in childhood.
A new study found that the link between paternal age and rare congenital disorders is more complex than previously thought. Researchers discovered that while older fathers are more likely to have children with certain bone and heart malformations, some genetic mutations associated with these conditions do not increase with paternal age.
Researchers at Salk Institute find a new method to interrupt sperm production using an HDAC inhibitor, which blocks fertility without affecting libido. The treatment's reversibility is attributed to its ability to modulate gene expression downstream of retinoic acid.
A large national study of over 6,000 patients found that video visits, texting and mailing pills were effective and safe for medication abortion. The research supports the safety and efficacy of telemedicine abortion, which has become increasingly important due to clinic closures and wait times.
A large study found that exposure to organophosphate ester flame retardants during pregnancy was associated with preterm birth, especially among female newborns. Higher birth weight was also linked to increased obesity risk. The chemicals are widely used in building materials, furniture, and electronics.
A new study found that e-cigarettes are more commonly used by pregnant smokers than nicotine patches, and regular use of nicotine products is not associated with adverse effects on mothers or babies. The study suggests that e-cigarettes can be a safe stop-smoking aid for pregnant women.
According to a study by Michigan State University, more Michigan adults now say they never want to have children due to the uncertainty surrounding reproductive health care following the Supreme Court's overturning of Roe v. Wade.
Scientists at University of California San Diego have developed a noninvasive approach to detect exRNA molecules in leftover culture media, which can help predict embryo quality and IVF success. By analyzing these molecules, the researchers were able to replicate morphological measurements used in current embryo tests.
A new study published in PLOS Medicine found no association between assisted reproductive technologies and body mass index in children, except when using frozen embryos. The study analyzed data from Denmark and other countries, providing insights into the health outcomes of children born through assisted reproductive technologies.
Participating in baby massage has been linked to lower rates of postnatal depression and improved parent-child interactions. A systematic review found that mother-led infant massage can have a positive impact on maternal mental health and relationships.
A large study of over 9,000 pregnant people found that cannabis exposure during pregnancy is associated with a composite measure of unhealthy pregnancy outcomes, including low birth weight. Higher levels of cannabis exposure were also linked to higher risks of complications.
A study found that prenatal discrimination and acculturation stress can alter the strength of infant brain circuits, potentially leading to increased risk for mental health disorders. The research suggests a critical role in treating individuals with kindness during pregnancy.
A study published in PLOS Medicine found that 90% of pregnant women in high-income countries lack key vitamins necessary for healthy pregnancies and fetal development. The situation is expected to worsen as more people adopt plant-based diets, leading to increased risk of nutrient deficiencies.
Regular aerobic exercise can help prevent and treat postpartum depression. Moderate-intensity exercises performed three to four times a week are particularly effective in reducing symptoms of the condition.
A study of 152 male gym enthusiasts found a significant lack of awareness about the risks of gym lifestyle on fertility. High levels of estrogen from protein supplements were linked to fertility issues, prompting a call for men to educate themselves about supplementation.
A new study highlights how perimenopausal women's periods may become unpredictable, heavy, and cause worse premenstrual symptoms. The research suggests that improved education and support are needed to manage these changes, including extra support in the workplace, emotional support from loved ones, and access to support groups.
Researchers found that sperm flagellar waveforms are primarily influenced by viscosity rather than shear rate, promoting energy-efficient beating behavior. Sperm adjust their power generation to respond to fluid dynamics, enabling efficient swimming against the flow in high-viscosity media.
A new study found that body image dissatisfaction during pregnancy varies widely among women, influenced by complex factors such as positive and negative experiences. Negative body image can have serious effects on the mother and baby, including depression, anxiety, and poor quality interactions. The research highlights the importance ...
A U of M Medical School professor has received a $3.5 million grant to develop a reproductive health curriculum for Tanzania that addresses the needs of people with disabilities. The project aims to improve healthcare services and build in-country capacity for comprehensive sexual and reproductive healthcare.
A new Cochrane review suggests that timed intercourse using urine ovulation tests can improve live birth and pregnancy rates, especially in women under 40. The study found that timing intercourse around the fertile period increased chances of successful conception by 20-28%.
A novel mitochondrial enzyme was identified as key to reproductive aging, increasing oocyte clustering with age and affecting fertility
A study published in JAMA Network Open found that many websites selling fertility tests make misleading claims about their effectiveness and limitations. The researchers called for increased regulation and oversight on the marketing of home fertility tests, which can lead to false reassurance or worry among women.
The study reveals that women physicians prioritize family building over career advancement, leading to a shift in their professional paths. Women in medicine experience significant alterations to their careers due to fertility concerns and family planning, contributing to ongoing gender disparities.
Mothers with a criminal record and care experience face negative judgements and excessive scrutiny due to their 'known' status. The study emphasizes the need for supportive dialogue across disciplinary boundaries to break cycles of stigma and social care involvement, focusing on safe spaces and trust-building for care-experienced mothers.
A new AI tool can identify sperm in severely infertile men in seconds, compared to the hours it takes scientists. The algorithm improves antiquated approaches and increases the chance of a couple conceiving their own biological children while reducing stress on sperm and increasing efficiency.
A study found that more than 40% of women who froze their eggs in their 30s were able to have babies when they returned to the fertility clinic. However, many didn't return or used other fertility treatments. Women who used frozen eggs had a lower miscarriage rate compared to those using fresh eggs.
New study finds that men who suffered from mild COVID-19 have lower sperm concentrations and motility even three months after recovery. The researchers believe that the virus may cause permanent damage to male fertility, leading to long-term decline in semen quality.
The Endocrine Society will discuss emerging technology and diabetes research, including a scientific statement on hormones and aging. Researchers will share studies on various aspects of endocrinology, such as PCOS, obesity, and endocrine-disrupting chemicals.
A new study finds that midwifery care is associated with higher levels of autonomy and respect during childbirth, particularly in community settings. Midwives attended 12% of births, mostly in hospitals, while community births were more common with midwife attendance.
A new E-MOTIVE solution dramatically improves outcomes for women experiencing postpartum haemorrhage (PPH), a leading cause of maternal mortality worldwide. The study found a 60% reduction in severe bleeding and fewer blood transfusions, potentially saving thousands of lives globally.
A study from Indiana University found that internet searches for abortion- and contraception-related terms increased significantly in states with trigger laws or pre-Roe bans after the June 2022 ruling. Searches surged 61% in these states, indicating concerns about impending restrictions on reproductive care access.
A new MSU study confirms the initial estimate that 20.9% of Michigan adults do not want children, closely matching the 21.6% found in the original study. This translates to approximately 1.7 million people in Michigan and 50-60 million Americans nationwide being child-free.
A study found similar birth outcomes for same-sex lesbian couples undergoing ART compared to heterosexual couples who conceived naturally or through ART. Infertility-related factors, not reproductive treatments, contribute to higher adverse birth outcomes in ART pregnancies.
A new study has confirmed that chronic THC use can negatively impact male reproductive health, including testicular function and sperm quality. Discontinuing use of THC for at least four months can partially restore these effects, providing a critical window for family planning and conception.
A new study published in JAMA Health Forum finds that nearly half of primary care physicians treating Medicaid patients provide prescription contraception, while only 10% offer longer-acting methods like IUDs and implants. The research highlights the need for policy approaches tailored to different physician specialties to ensure acces...
A study found that gestational iron deficiency may contribute to cognitive impairments like autism, ADHD, and learning disabilities. Researchers identified a specific embryonic neuronal progenitor cell target for GID, which disrupts interneuron development.
Scientists at the Wyss Institute and Gameto develop a living, fully human ovarian organoid that supports egg cell maturation and secretes sex hormones. This technology enables the study of human ovarian biology without tissue from patients and could lead to new treatments for infertility and ovarian cancer.