Articles tagged with Disease Intervention
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A Japanese study found that lower masseter muscle volume is associated with increased sarcopenia risk, particularly in men. The research suggests using MRI measurements of MMV for early diagnosis and personalized interventions.
A new UCLA study categorizes people with chronic liver disease into four unique risk groups based on barriers to outpatient care, increasing the likelihood of hospitalization. The study highlights the need for interventions aimed at reducing avoidable hospitalizations among the highest-risk individuals.
A cross-sectional study found significant increases in postpartum depression diagnosis among all racial and ethnic groups and body mass index categories over the past decade. The persistently high rates underscore the need for preventative interventions to mitigate PPD's impact on maternal and child health.
Research suggests that lifestyle modifications and metformin do not improve atrial fibrillation (AFib) burden or progression when compared to standard care. In contrast, weight loss and exercise resulted in decreased AFib symptoms in patients with the condition.
The American College of Lifestyle Medicine has partnered with the US Space Force to provide lifestyle medicine education, training, and certification to Guardian Resilience Team members. This initiative aims to enhance Space Force service members' health and performance through evidence-based lifestyle interventions.
Researchers found that podcasts significantly improved health knowledge, increased exercise levels, and boosted healthy eating habits. Engagement with health-related podcasts was generally high, suggesting they could be an effective medium for health information and behavior change interventions.
A study reveals disproportionate burden of cardiovascular-kidney-metabolic syndrome among certain populations, emphasizing the need for targeted interventions. The research highlights the importance of addressing socioeconomic disparities in cardiovascular health.
Studies published in JACC found that anti-obesity drugs such as tirzepatide and semaglutide improved cardiac structure and function, as well as reduced cardiac risk biomarkers with lifestyle interventions. These findings suggest that these treatments may have a transformative impact on cardiovascular health beyond weight loss.
A study found that pharmacists who received feedback about their heart failure patients increased the frequency of their patient interactions and prescribed more medication adjustments. The intervention, which provided educational resources and monthly audit and feedback emails, led to a significant increase in heart failure management.
A new study reveals that US college students who use dating apps are more likely to engage in risky sexual behaviors, including unprotected sex and multiple partners. The study suggests a vicious cycle where dating app use contributes to increased risks and vice versa.
According to the American Heart Association's Life's Essential 8, primary care clinicians can help patients reduce their risk of heart disease by addressing modifiable risk factors through lifestyle changes and treatment. Despite challenges, research shows that primary care professionals with a higher ratio have lower total costs of ca...
Researchers found that non-invasive stereotactic radiosurgery significantly improves tumor control and reduces symptoms such as tinnitus, cranial nerve deterioration, and vestibular dysfunction. Early treatment can prevent tumors from growing over time and spare patients from irreversible problems.
A study by the University of Gothenburg found that unclear procedures and distribution of responsibilities among healthcare workers can lead to poor oral health in older adults in nursing homes. The researchers suggest that a more structured process can promote communication and awareness of good oral health practices.
A new study introduces the Meuhedet Electronic Frailty Index (MEFI) to assess frailty in older people and identify those at risk for serious health outcomes. The index classifies individuals as 'fit,' 'mildly frail,' or 'severely frail' and has been shown to predict mortality and hospitalization with high accuracy.
Researchers analyzed nearly 200,000 cases of witnessed out-of-hospital cardiac arrests to determine the effectiveness of bystander CPR within different time windows. The study found that people who received CPR within the first few minutes had a higher survival rate and better brain function than those who didn't.
A study by University of Pittsburgh researchers found that Black patients are two to three times as likely to retain or gain additional weight compared to white counterparts. The study suggests interventions addressing the underlying stressors of discrimination could complement community and clinical interventions.
This study reveals prevalent adverse childhood experiences among children, including abuse and neglect, with notable disparities across demographics. Early identification and community interventions can reduce ACEs and mitigate future health consequences.
A global study of nearly 30,000 participants found that frailty accelerates dementia diagnosis by up to 9 years, with every additional health problem increasing the risk by 40%. Researchers emphasize the importance of targeted interventions and frailty screening for early disease prevention.
A new two-year grant will support research on the intersection of alcohol use and intimate partner violence among bisexual+ young adults. The study aims to identify factors contributing to alcohol-related partner violence and inform interventions tailored to this vulnerable population.
Researchers developed a new imaging technique using fluorescence-guided surgery to enhance visibility of tumors and nerves during head and neck cancer surgery. The technique uses two near-infrared fluorophores, one for tumors and another for facial nerves, allowing for clear differentiation between cancerous tissues and nerves.
A digital health behavior intervention improved child weight-for-length trajectory and reduced childhood obesity at 24 months. The intervention was effective in a racially and ethnically diverse population, including groups at elevated risk for childhood obesity.
A new study finds that quitting smoking within six months of a cancer diagnosis significantly improves survival, with the largest benefit among patients who quit soonest. This evidence-based approach highlights the urgent need for cancer centers to offer smoking cessation programs to all patients.
A systematic review reveals exercise reduces alcohol dependence while improving mental and physical health in patients with alcohol use disorder. The study also found that exercise interventions can lead to significant improvements in symptoms and quality of life.
Researchers found a specialized low-salt, fasting-mimicking diet (LS-FMD) slows deterioration of kidney structures and function in rodents with chronic kidney disease. In humans, the diet reduced proteinuria and improved endothelial function in patients with chronic kidney disease.
A study led by WVU epidemiologist Bethany Barone Gibbs found that alternating sitting and standing at work reduces sedentary behavior but has no effect on lowering blood pressure. Prolonged static standing may even have negative effects on cardiovascular health due to a physiological mechanism called the muscle pump.
Researchers tested a model of depression care in Malawi using the country's existing HIV delivery system, involving clinical officers and community personnel. The intervention showed improvements not only in depression but also in other chronic health conditions and household members' wellbeing.
A comprehensive review of global evidence highlights the devastating effects of family violence on mental and physical well-being. The study, involving over 3 million individuals, reveals a strong connection between family violence and various adverse health outcomes.
The study found a significant decrease in the percentage of adolescents reporting current marijuana use, from 23.1% in 2011 to 15.8% in 2021. Marijuana use was most prevalent among 12th graders, with a notable decline in usage rates across all grades.
A recent study published in JAMA Network Open found that 84% of adults with congenital heart disease reported good or better health-related quality of life, despite complex CHD. However, participants with complex CHD were less likely to meet physical activity guidelines and reported mood disorders.
A study by Dr. Hernan Bazan at Ochsner Health reveals that higher frailty scores are directly associated with increased rates of stroke, death, and myocardial infarction within 30 days of the carotid procedure. The Hospital Frailty Risk Index provides a systematic tool for assessing frailty risk across large populations.
The EAT2 study, led by Dr. Ursula White, investigates the lasting health effects of short-term weight gain and loss on fat tissue and overall health. Participants will undergo a dietary intervention program followed by an eight-week weight loss treatment.
A peer-reviewed study published in NEJM Catalyst found Waymark's early intervention model significantly improved clinical outcomes for patients receiving Medicaid, reducing hospital and ED visits by 22.9%. The study also showed improved patient goal completion and care quality.
A new methodology has been introduced that significantly enhances the accuracy of epidemiological estimates for infectious diseases like COVID-19. The approach adopts a history-dependent framework, eliminating biases in traditional models and allowing for more precise predictions of disease spread.
A University of Michigan-led study found that treatment with either modafinil or cognitive behavioral therapy alone was associated with significant reductions in fatigue over 12 weeks. A combination of both treatments worked as well as each individual treatment but did not result in better fatigue scores.
A recent study analyzing data from the ANCORS-YW study found that overweight and obese women in this region are at a higher risk of hypertension and cardiovascular disease. Researchers recommend tailored preventive strategies, including lifestyle modification programs and socioeconomic support, to address this public health challenge.
A new study found that people with severe mental illness are more likely to experience fragility fractures than the general population. The researchers analyzed GP records of over 440,000 people between 2000 and 2018 and found a significant association between severe mental illness and fragility fractures.
A new study evaluated the efficacy of a combined hearing and vision rehabilitation intervention for people with dementia living at home. The SENSE-Cog trial showed significant improvements in quality of life in the short term, but further research is needed to understand its long-term impact.
The Lancet Commission on Investing in Health recommends focusing on 15 priority health conditions to achieve a 50% reduction in premature deaths. Raising taxes on tobacco is key, with estimates suggesting it could reduce mortality rates by more than any other single policy.
A new report argues that countries can cut premature mortality in half by 2050 through targeted health investments. By prioritizing the 15 health conditions causing most premature deaths and implementing public subsidies for essential medicines and diagnostics, nations can achieve this goal.
Researchers have developed a new approach to epidemic modeling that considers socioeconomic factors like income, education, and ethnicity. This framework allows for more realistic predictions of disease spread by accounting for how people interact and respond to public health measures.
A cross-sectional study reveals a significant risk of suicidal thoughts and behaviors among autistic transgender and gender-nonconforming US college students. The study emphasizes the importance of providing targeted support to address this issue.
A new study from UCSF has found that ChatGPT overprescribes in emergency care situations, providing unnecessary x-rays and antibiotics. The AI model was less accurate than resident physicians, with a tendency to err on the side of caution. Researchers emphasize the need for better frameworks to evaluate clinical information before AI c...
Researchers argue that stigma can play a huge role in health outcomes, leading to disengagement from care, coerced sterilization, and lack of informed choices. Addressing stigma through evidence-based approaches, such as staff training and relationship building, can improve healthcare services.
A study suggests that online insomnia treatment, SHUTi, can provide meaningful relief for caregivers struggling with sleep difficulties. The program showed promising results in improving sleep quality and reducing stress among high-intensity caregivers, those shouldering the greatest responsibilities in caring for their loved ones.
A new study aims to increase follow-up care for patients who receive abnormal stool-based fecal immunochemical tests, focusing on improving coordination between primary and specialty clinics. The goal is to improve colorectal cancer screening processes in underserved populations, increasing survival and reducing mortality.
A global study reveals that women's environmental quality of life explains a substantial 46% of their overall health and well-being. The study found that younger women report poorer environmental quality of life, while older women experience improved quality of life after age 45.
The expert panel discussion sheds light on the best practices for injecting hyaluronic acid (HA) fillers in the infraorbital hollows. Top surgeons share their preferred fillers and techniques, providing valuable insights for treating undereye dark circles.
A clinical trial found time-restricted eating improved blood sugar regulation and reduced markers of metabolic dysfunction in adults with metabolic syndrome. Participants who followed a customized eight-to-ten-hour eating window saw significant improvements compared to standard treatments.
A research team led by Maria Glymour will investigate four modifiable risk factors for ADRD: lifetime alcohol use, depression, vision and hearing impairments, and social isolation. The project aims to provide comprehensive evidence on how these risk factors contribute to ADRD risk.
A recent study found that limiting food consumption within a 10-hour window per day improved key indicators of heart health in adults with metabolic syndrome. The study demonstrated significant reductions in blood sugar and cholesterol levels, as well as lower levels of hemoglobin A1c, a marker of long-term blood sugar management.
A randomized clinical trial found that a voice-activated cognitive behavioral therapy program improved insomnia symptoms in breast cancer survivors. The intervention, delivered in an in-home setting, demonstrated efficacy in reducing sleep disturbances and enhancing overall quality of life.
Video games created as mental health interventions can be modest tools in improving the mental well-being of children and teens with anxiety, depression, and ADHD. These digital mental health interventions showed a reduction in symptoms related to ADHD and depression, but not for anxiety.
A systematic review and meta-analysis of over 3.6 million mother-child pairs found that maternal obesity during pregnancy significantly linked with psychiatric and behavioral problems in children later in life, including autism spectrum disorder and attention deficit hyperactivity disorder.
This study suggests that gamified digital mental health interventions can be an effective treatment option for youth with ADHD or depressive disorders. The findings provide new information for pediatricians and healthcare professionals seeking innovative solutions for pediatric mental health care.
A recent Cochrane review confirms that giving women at risk of premature birth a simple magnesium sulphate infusion can prevent their babies from developing cerebral palsy. The drug costs approximately £5 (~$6.50) per dose and has been recommended by the World Health Organization since 2015.
Scientists analyzed millions of tweets to detect early warning signs of PTSD in COVID-19 survivors, achieving an accuracy rate of 83.29%. The study highlights the potential for machine learning techniques to identify individuals at risk of PTSD through social media data.
A cross-sectional study in California finds that legacies of redlining contribute to increased severe maternal morbidity, highlighting the need for place-based interventions. The study suggests that addressing structural drivers of adverse pregnancy outcomes and racial inequities is crucial.
A new study of nearly 2,000 former NFL players shows that about one-third believe they have chronic traumatic encephalopathy (CTE), a condition linked to repeated head trauma. Players who believed they had CTE reported more cognitive problems and higher rates of treatable conditions such as depression and low testosterone.
Scientists at Stanford University have developed a new method to relocalize misplaced proteins in cells, which could lead to therapeutic treatments for diseases. The team created a class of molecules called TRAMs that convince natural shuttles to take cargo like proteins to different parts of the cell.
A nonrandomized clinical trial found that wearable devices can increase moderate-to-vigorous physical activity and reduce dyspnea at 6 months post-lung cancer surgery. This suggests a promising role for wearable devices in personalizing perioperative rehabilitation strategies.