Articles tagged with Disease Prevention
A McGill University study reveals that vitamin D deficiency early in life can lead to a higher risk of autoimmune diseases like Type 1 diabetes. The research found that an aging thymus causes the immune system to become less effective, increasing the risk of misdirected immune cells attacking healthy tissues.
Researchers found that using valacyclovir for a year can decrease the risk of new or worsening eye disease and prevent vision loss associated with shingles. The study, which enrolled over 500 participants, showed that this treatment reduced the risk of complications by 30%.
A study at Boston Children's Hospital highlights the complexity of infection prevention and control measures in pediatric healthcare. The conventional method of calculating IP staffing needs does not accurately reflect the current demands of healthcare systems or pediatric patients, leading to a shortage of resources.
A special issue of the Journal of the Academy of Nutrition and Dietetics reviews the history of the Women's Health Initiative, which has contributed significantly to the science of nutrition. The initiative's findings have led to a reduction in breast cancer cases and improved blood lipid management among postmenopausal women.
Experts from The Independent Panel for Pandemic Preparedness and Response urge leaders to take action against Mpox, a more dangerous virus now spreading across borders. The previous outbreak was neglected, highlighting the need for increased investment and cooperation to prevent further harm and global spread.
New research confirms that young adults are at risk for large vessel occlusion acute ischemic strokes, which were previously thought to occur mainly in older adults. The study found that nearly 20% of a cohort of 1,200 young adult patients had these strokes, highlighting the need for regular check-ups and prompt treatment.
A new app has tracked travel-related illnesses globally, showing that travelers experience health issues more often than expected. The Illness Tracking in Travellers (ITIT) app recorded gastrointestinal symptoms most frequently among Asian travelers and respiratory diseases in Europe.
A new report argues that countries can cut premature mortality in half by 2050 through targeted health investments. By prioritizing the 15 health conditions causing most premature deaths and implementing public subsidies for essential medicines and diagnostics, nations can achieve this goal.
A new study published in the American Journal of Infection Control found that nearly 4 in 5 hospitals are not staffed at sufficient levels to keep patients safe from preventable infections. The study highlights the need for customized infection prevention staffing recommendations, which can be provided by an online calculator tool.
A new study found that COVID-19 infection increased the risk of heart attack and stroke for up to three years after infection. The risk was higher among people with A, B or AB blood types compared to type O, according to researchers analyzing data in the UK Biobank.
A new supplement celebrating the 100th volume of the Journal of Alzheimer’s Disease presents insights into the state of art in AD research. Recent advancements in geroscience have led to the development of preventive medical strategies targeting aging, holding promise for reducing disease risk.
A recent study found that smokers report higher rates of chronic pain, poor mental health, and severe work limitations due to pain. Quitting smoking can reduce prescription opioid use and associated health problems, emphasizing the need for integrated treatment programs.
A systematic review and meta-analysis found that weight-loss surgery reduces pancreatic cancer risk among individuals with obesity by 44%, and among those with both obesity and type 2 diabetes by 79%. The study suggests that metabolic-bariatric surgery may play a crucial role in reducing the risk of pancreatic cancer.
A new study in the American Journal of Preventive Medicine found that quitting smoking even at 75 can significantly increase life expectancy. The research showed that older individuals who quit smoking can avoid an average loss of 4-9 years of life, with some regaining up to 8 years or more.
A new Canadian study models a 1-dose HPV vaccination approach and finds it could prevent a similar number of cervical cancers as 2 doses if vaccine protection remains high. The switch is projected to be a more efficient use of vaccine doses, potentially eliminating cervical cancer in Canada by 2040.
Researchers found that intestinal absorption of fats plays a crucial role in preventing diet-induced fatty liver disease. The absence of gut hormones, such as proglucagon-derived peptides, prevents fat accumulation by reducing lipid absorption from the intestines.
The authors emphasize the importance of increasing vaccination rates to combat decreasing rates globally. They also highlight emerging challenges such as a highly virulent strain of influenza and measles outbreaks, particularly in areas with low vaccination rates.
A comprehensive review of population-level tobacco control strategies found tax increases, smoke-free legislation, and anti-smoking campaigns to be effective in reducing smoking. These interventions also increased quit rates and led to higher smoking cessation rates.
Two new papers estimate economic value of reducing avoidable deaths worldwide, finding 40 million deaths in 2019 were avoidable. The economic value is equivalent to 23% of annual global income, suggesting health improvements could lead to substantial economic benefits.
A recent study published in The Lancet Public Health found that body weight is a significant factor in pregnancy complications, affecting women born in different countries. Researchers estimated that approximately half of all cases of gestational diabetes could be prevented if all women were of normal weight during pregnancy.
The researchers aim to establish targets for the vaccine by identifying proteins on the surface of early-stage ovarian cancer cells recognized by the immune system. If successful, clinical trials will begin to test the vaccine's effectiveness in preventing ovarian cancer, potentially offering a solution for women at high risk.
A new study published in JAMA Network Open found that racial and ethnic minorities are more likely to have claims for free preventive care denied by insurance plans, leading to unexpected bills or lack of access. Healthcare providers also charge disadvantaged groups a higher amount for preventive services.
Researchers have developed a peptide inhibitor called RI-AG03 that effectively prevents Tau protein aggregation in lab and fruit fly studies. The breakthrough targets both major aggregation-promoting 'hotspots' of the Tau protein, potentially paving the way for more effective treatments for neurodegenerative diseases.
A study found that doxycycline post-exposure prophylaxis (doxy-PEP) did not significantly alter the overall composition of gut bacteria in individuals who took it for six months. However, the researchers noted signs of resistance building against tetracycline, a class of antibiotics to which doxycycline belongs.
A six-month study found that reducing daily sitting by 40 min/day can prevent back pain from worsening. The researchers suggest trying to reduce sitting at work or leisure time, but emphasize the importance of physical activity such as walking or brisk exercise.
A new study suggests that banning the purchase of cigarettes and other tobacco products among people born between 2006 and 2010 could prevent an estimated 1.2 million lung cancer deaths in 185 countries by 2095. This could reduce the impact of smoking on lung cancer deaths in future generations.
A modelling study suggests that reducing tobacco smoking globally to 5% by 2050 could increase life expectancy and prevent millions of premature deaths. Accelerating actions to eliminate tobacco smoking could result in up to 1.5 additional years of life expectancy among males and 0.4 years among females.
Researchers have created the largest and most complete map of the fruit fly brain, detailing over 50 million connections between neurons. The study provides critical information about brain wiring and underlying signals, paving the way for future studies on larger-brained animals.
The American College of Chest Physicians has released a new clinical guideline on endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) specimen processing and handling to standardize the process. The guidelines aim to improve diagnostic yield and specimen preservation for downstream ancillary testing.
A research team led by Maria Glymour will investigate four modifiable risk factors for ADRD: lifetime alcohol use, depression, vision and hearing impairments, and social isolation. The project aims to provide comprehensive evidence on how these risk factors contribute to ADRD risk.
A new study published in the Journal of the American College of Cardiology found that subclinical atherosclerosis is independently associated with the risk of dying from any cause. The study also showed that monitoring the progression of atherosclerosis can improve the prediction and prevention of death from any cause.
Researchers at the University of Arizona Health Sciences are studying the molecular mechanisms of coagulation factor XII as a contributor to heart failure with reduced ejection. The goal is to develop better preventive and treatment options for this irreversible condition, which affects millions of Americans.
Researchers identified T. immunophila as a key player in breaking down the gut's protective immune barrier, leading to increased susceptibility to pathogens and delayed repair of the gut barrier. The discovery provides a promising new avenue for treatment of inflammatory bowel disease, Crohn's, and ulcerative colitis.
According to the Global Cancer Observatory (GLOBOCAN), lung cancer is the most common type of cancer, with 2.2 million new cases and 1.8 million deaths worldwide in 2020. China had the highest number of new cases, and incidence and mortality rates have been steadily rising from 1990 to 2019.
A new study found that climate change may lead to a significant increase in diarrheal disease hospitalizations in Dhaka, Bangladesh, even if global warming targets are met. Hospitalization rates could rise by 4.5-7.4% due to warmer temperatures and worsening water quality.
Researchers developed a nasal spray that captures and neutralizes airborne viruses and bacteria, providing up to 8 hours of protection. The Pathogen Capture and Neutralizing Spray (PCANS) demonstrated a greater than 99.99% reduction in lung viral titers in mice models.
Researchers have developed an antibody that can identify Campylobacter jejuni and inhibit its growth, reducing pathogenicity. The antibody targets a multiprotein complex essential for the bacteria's energy production, making it a potential target for therapy and vaccination.
The American Heart Association joins a $10 million grant from the Global Cardiovascular Research Funders Forum for international scientific research on cardiovascular health in women. The International Research Challenge aims to address significant gaps in research, diagnosis, and care for women worldwide.
A large study found that women with premature ovarian insufficiency are 2.6 times more likely to have an autoimmune disorder, with some conditions increasing the risk by 26 times. The study suggests a strong link between POI and severe autoimmune diseases, highlighting the need for medical professionals to be aware of this increased risk.
A new study found that a high body roundness index over 6 years was associated with an increased risk of developing cardiovascular disease in adults older than 45. The study, published in the Journal of the American Heart Association, suggested that BRI may be a valuable predictor of cardiovascular disease risk.
A new study found that nursing shortages result in longer hospital stays and worse patient outcomes, including higher mortality rates. Understaffing by registered nurses and nurse assistants is associated with increased risks of adverse events, such as readmissions, deep vein thrombosis, pneumonia, and pressure ulcers.
Researchers have identified nearly 200 potential breast carcinogens in food contact materials, including plastics and paper, highlighting widespread exposure despite existing regulation. The findings emphasize the need for stronger preventative measures to reduce these chemicals in everyday products.
The 2024 guideline provides comprehensive recommendations for assessing cardiovascular disease risk and managing patients taking SGLT2-inhibitors. It also highlights the importance of judicious screening and evidence-based management of cardiovascular conditions before, during, and after noncardiac surgery.
A new poll from Michigan Medicine shows that nearly half of people age 50 and older plan to get the updated COVID-19 vaccine. However, some older adults with high risk of severe illness appear unlikely to seek the vaccine, highlighting the need for increased encouragement from clinicians and other sources.
Researchers at Mizzou have developed Cryo2Struct, a computer program that uses AI to build the three-dimensional atomic structure of large protein complexes from cryo-electron microscopy images. This breakthrough enables scientists to better understand protein interactions, critical for developing effective treatments for diseases like...
A new study found that up to 10 million people in the US could qualify for Medicare-covered semaglutide injections, depending on their level of cardiovascular risk. Those with higher risk scores would be eligible for full or partial coverage, potentially expanding access to this life-saving medication.
A new study has identified the genetic factors driving cholera's severity and spread. The research, led by Professor Tania Dottorini, found that unique genes and mutations in Vibrio cholerae are linked to prolonged diarrhoea, intense abdominal pain, and dehydration.
A new study led by Uppsala University researchers found that a single treatment session playing the video game Tetris can reduce PTSD symptoms. After five weeks and six months, participants showed significant improvements in reducing intrusive memories and alleviating other symptoms.
A Virginia Tech research team has identified a molecular mechanism by which Shigella flexneri bacteria manipulate host molecules to ensure their survival. The study provides a new understanding of the infection pathway and its potential implications for preventing similar infections in other bacteria.
A Nagoya University study suggests adopting testing-based protocols to minimize both premature and prolonged isolation for mpox patients. The approach characterizes viral shedding dynamics to optimize isolation strategies, potentially reducing patient isolation times by more than a week on average.
A pioneering study identified critical biomarkers that can predict disability worsening in MS. Elevated serum neurofilament light chain and serum glial fibrillary acidic protein levels correlate with progression independent of relapse activity, guiding personalized treatment approaches.
Regenstrief researcher Andrew Gonzalez proposes developing an AI chatbot to identify PAD in asymptomatic individuals, providing clinicians with critical information to make informed decisions. The project aims to improve diagnosis and reduce diagnostic errors, particularly among vulnerable populations.
A new study reveals that two specific genes in the RNA interference pathway play a crucial role in preventing virus transmission from parent to progeny in plants. This discovery could lead to healthier crops and potentially reduce the transmission of diseases like Zika from mothers to human children.
A study finds that cardiometabolic indicators like metabolic syndrome and diabetes impair coronary microvascular function, increasing cardiovascular risk. The presence of subclinical atherosclerosis also contributes to altered microvessel function.
The global stroke burden has increased significantly over the past three decades, driven by rising levels of air pollution, high temperatures, and metabolic risk factors. The study found that the number of people experiencing new strokes rose to 11.9 million in 2021, with an additional 93.8 million survivors and 7.3 million deaths.
A study by Amber Salter found that people with multiple sclerosis (MS) who have comorbidities experience worsened disease activity. The research highlights the importance of addressing comorbidities in MS treatment.
A nationwide multi-cohort study found that residence in low-income-low-food-access neighborhoods during pregnancy or early childhood significantly raises the risk of obesity and severe obesity from childhood to adolescence. The study underscores the importance of early-life neighborhood environments in shaping child health outcomes.
A new study estimates that more than 1 million people died each year due to antibiotic-resistant infections between 1990 and 2021. The study predicts that this number could increase to nearly 2 million by 2050, with a significant age-related shift in the impact of AMR on children under five years old.
A new scientific statement emphasizes the role of social determinants, such as immigration status, socioeconomic position, and access to healthcare, in shaping cardiovascular health among Asian American adults. The statement identifies future research directions to advance health equity and reduce disparities in these communities.
The new European Society of Cardiology Guidelines recommend regular screenings for Peripheral Arterial Disease (PAD) to prevent complications. The guidelines also emphasize personalized treatment plans, including lifestyle changes, medication, and efficient blockage treatments.