New ways to pressure HIV
Researchers found that unique reading frames in the HIV genome can induce immune responses, potentially leading to new ways to combat the virus. These findings may prove useful for developing more effective HIV vaccines.
Immune Cells
Articles tagged with Immune Cells
The right messenger for a healthy immune response
Researchers from the Helmholtz Center for Infection Research found that Beta-Interferon facilitates faster immune reactions against microbial and viral threats by regulating antigen presentation. Low levels of Beta-Interferon before infection can lead to a stronger immune response, known as priming.
Opioids provide relief from neuropathic pain
A mouse model of neuropathic pain showed that immune cells producing opioids reduced symptoms, suggesting a novel approach for pain relief. Selectively targeting opioid-containing immune cells may provide natural pain relief and offer a new treatment option.
Interferon could be a key to preventing or treating multiple sclerosis
Interferon-gamma plays a deciding role in whether immune cells attack and injure the central nervous system in mice. The protein is protective in cerebellums and brainstems but causes nerve cell damage in spinal cords.
Form of Crohn's disease traced to disabled gut cells
Research finds disabled gut cells linked to Crohn's disease, with altered genetic activity leading to increased hormone production. The study suggests a potential role for autophagy and Atg16L1 in Paneth cell function, shedding light on the complex mechanisms behind the inflammatory bowel disorder.
Effective cancer immune therapy through order in the blood vessels
Researchers discovered a key molecule that normalizes tumor vasculature, allowing immune cells to colonize cancer tissue in large numbers. This finding led to improved survival rates in mice with disrupted Rgs5 gene, highlighting the potential of vascular normalization for enhancing immune therapy.
Caffeine prevents multiple sclerosis-like disease in mice
Researchers found that caffeine protects mice from developing experimental autoimmune encephalomyelitis (EAE), a model for human Multiple Sclerosis (MS). Caffeine's ability to block adenosine receptors may be key to preventing immune cell infiltration into the central nervous system.
In the laboratory, green tea proves a powerful medicine against severe sepsis
A new study found that green tea's EGCG ingredient can rescue mice from lethal sepsis, paving the way for clinical trials. The substance works by preventing HMGB1 from being released and activating immune cells.
Immune mechanism could help explain transient immune suppression often seen in acute infections
Researchers found that lymphoid chemokines, which guide immune cells to lymph nodes and spleen, are reduced during active immune responses, potentially leading to transient immune suppression. This discovery could help explain why the immune system is less effective at responding to secondary infections after an acute infection.
Damaged motor neurons in ALS contribute to their own death
Researchers discovered that damaged motor neurons in ALS send incorrect signals, triggering an immune cell response that accelerates their own death. This finding offers a new approach for therapies targeting the motor neurons themselves.
Immune culprit in malaria-associated anemia
Malaria infection hampers red blood cell production, leading to severe anemia. A new study reveals MIF as the key immune player in this process.
Fatty foods fight inflammation
Researchers have discovered that eating fatty foods can dampen inflammation in the gut by stimulating the production of cholecystokinin, a hormone that sends signals to the brain and immune cells. This process may provide a way to reduce inflammatory complications after surgery.
Leukemia, infection tied to aging stem cells, Stanford researchers say
Researchers at Stanford University have found a connection between aging, infection, and leukemia in blood-forming stem cells. These cells were found to produce fewer immune cells and turn on cancer-causing genes, contributing to the development of certain types of leukemia.
Immune cells' genetic 'jam session' is controlled by cell division machinery
Researchers from Johns Hopkins report that the band leader controlling DNA copying also brings the jam session to a close, intricately connecting the two processes. This discovery sheds light on the development of immune system cancers.
Tai chi chih boosts shingles immunity in older adults
A new study finds that tai chi chih significantly increases immune cell levels and improves physical functioning in older adults with shingles. The exercise program was comparable to hip replacement surgery in boosting immunity and reducing symptoms.
Scientists find hidden piece of influenza virus
Researchers have found a new, hidden piece of the influenza virus that may kill immune system cells. This protein was discovered by accident while studying
High Levels of Vitamin C Prove Toxic to HIV
Researchers found that HIV-infected immune cells take in more vitamin C and glucose than healthy counterparts, but extremely high levels are toxic. This study provides a foundation to understand the relationship between vitamin C, HIV infection, and cell metabolism.