Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
Severe RSV disease among children is more likely those aged 2 or older with pulmonary or neurologic conditions. Younger children under 6 months and prematurity are high-risk factors for severe RSV in younger kids.
A major Danish nationwide cohort study found that adults with respiratory syncytial virus-associated acute respiratory infection (RSV-ARI) experience significantly worse health outcomes, including a 2.7-fold higher risk of death within one year compared to the general population. RSV-ARI also leads to exacerbations of COPD and asthma, ...
Regional mesylate anticoagulation in centrifugation artificial liver support systems is safe for liver failure patients at risk of bleeding. Adjusting the mesylate dose based on pre-R and pre-MA enhances safety.
The American Heart Association will strengthen and expand Hawaii's stroke system of care, reducing death and disability rates from stroke in rural populations. The initiative aims to enhance coordination among emergency responders, hospitals, and healthcare providers.
A new study found that death rates from alcohol in England increased by a fifth in 2020, rising further between 2020 and 2022. The largest increases were among men, people from deprived areas, and those aged 50-69, mainly due to liver damage caused by alcohol.
Researchers have found that puberty triggers significant changes in brain connectivity patterns in individuals with a rare genetic disorder tied to autism. The study suggests that synaptic dysfunction during development may contribute to the condition's behavioral challenges.
A study published in Heart Rhythm has found that handheld electro-shockers can interact with cardiac implantable electronic devices (CIEDs) such as pacemakers, posing a risk to individuals. The risk is primarily based on the applied voltage, but also on the manufacturer and type of implanted CIED.
A new NIH study found that children born in lower-opportunity neighborhoods are more likely to experience repeated asthma flares requiring emergency care. Non-Hispanic Black children have the highest incidence rates of severe childhood asthma, also known as asthma with recurrent exacerbations (ARE).
Researchers have identified a potential precision medicine approach to prevent chronic kidney disease progression by targeting type 5 collagen, a minor component of scar tissue. A repurposed anti-cancer drug, Cilengitide, has been shown to slow kidney scarring and disease progression in high-risk individuals.
The WNFC's player ambassadors will amplify public service announcements, social media content, and local community education events to raise awareness about cardiovascular disease and CPR education in women. The league has also implemented a requirement for all coaches to be certified in CPR, AED, and first aid.
Researchers have initiated a clinical trial using an investigational medicine to lower amyloid precursor protein, targeting Alzheimer's disease in adults with Down syndrome. The study aims to prevent the development of Alzheimer's disease by addressing its underlying genetic cause.
A new study published by the American Academy of Neurology found that having a father with Alzheimer's disease may be associated with a greater spread of tau protein in the brain. Female participants also showed a heavier buildup of tau protein, highlighting potential vulnerabilities.
A study by the Barcelona Institute for Global Health found that Europe has adapted better to cold temperatures than to heat over the last two decades. The relative risk of death in low temperatures decreased by 2% per year, while the risk from extreme heat fell by 1% per year.
A systematic review of nearly 6000 runners found that lower energy and fat intakes were strongly associated with a higher risk of injury in female runners. A low-fibre diet also increased the likelihood of bone stress injuries.
A new study found that a 2018 US public housing smoking ban led to reduced hospitalizations for cardiovascular problems. The ban resulted in modest declines in heart attacks incidence rates and small differential declines in strokes among adults aged over 50.
Researchers used data from 9,000 pregnancies to discover and validate RNA signatures that distinguish between severe and mild hypertensive disorders of pregnancy. The study validates Mirvie's simple blood test to predict preeclampsia early, at 17.5-22 weeks gestational age.
A two-week in-patient study found that eating during the day but not at night reduced cardiovascular risk factors in healthy young participants after simulated night work. This finding supports adjusting food timing to mitigate health risks associated with shift work.
A new study found that genetic predisposition to sedentary behavior is associated with a higher risk of developing the most common cardiovascular diseases. Individuals with the highest genetic predisposition accumulated more daily sedentary time and had a 20% higher risk of cardiovascular diseases.
A recent study found that parental metabolic traits, particularly those of the mother, can significantly affect a child's cardiometabolic health. The research showed that mothers have a greater impact on blood sugar and cholesterol levels in their children, while fathers' genes play a stronger role in insulin function over time.
A French cohort study of over 100,000 adults found that mixtures of common food additives, including aspartame and carrageenan, were associated with a slightly increased risk of type II diabetes. The study suggests that these additives may have adverse effects on glucose metabolism.
A study found that migrants experience a 'clear change' in their gut microbiome composition after migration, leading to increased rates of cardiovascular disease. The Amsterdam UMC-led research showed that specific groups of microbes disappear or emerge along the migration axis.
Invasive group A Streptococcus infections increased substantially in 10 US states between 2013 and 2022. Accelerated prevention efforts are needed, especially among high-risk groups, to combat the spread of this bacterial infection.
A meta-analysis of randomized clinical trials found that glucagon-like peptide-1 receptor agonists (GLP-1RAs) were associated with a statistically significant reduction in all-cause dementia. Cardioprotective glucose-lowering therapies, however, did not show an overall reduction in dementia risk.
Research reveals that GLP-1RAs and SGLT2i medications significantly reduce the risk of Alzheimer's disease and related dementias in people with type 2 diabetes. No significant difference was found between these two treatments.
A new study published in The Lancet Psychiatry found that ADHD medications have small but significant effects on blood pressure and heart rate. While there were concerns about the side effects of these medications, the study suggests that their benefits outweigh the risks.
The Ralph L. Sacco Scholarships in Brain Health support research into vascular disease's impact on cognitive decline, dementia, and brain health. Researchers Hortense Triniac and Katy Walsh will study protein interactions to reduce stroke risk and investigate cerebral amyloid angiopathy.
A study of nearly 30,000 adults found that heart failure is associated with a significant decrease in cognition at diagnosis and rapid decline over time. Adults with heart failure reach the threshold for meaningful decline in global cognition nearly six years earlier than those without it.
A global study led by UCalgary researchers found that one in five people who experience a minor stroke or TIA will have another stroke within 10 years. The study analyzed data from over 171,000 patients across four continents and shows a persistently high risk of future strokes for at least a decade.
A longitudinal study found that individuals living in neighborhoods with low walkability had a higher risk of cardiovascular disease, even after adjusting for sociodemographic characteristics. The study highlights the importance of long-term urban planning for cardiovascular health.
A study found that pedometers capture a remarkable 88% of the health information provided by more advanced accelerometer measurements. Walking at a brisk pace is essential for cardiovascular health optimization, with a minimum cadence of 80 steps per minute strongly associated with good aerobic fitness.
Mass General Brigham researchers have identified 17 modifiable risk factors shared by stroke, dementia, and late-life depression. Modifying any one of these risk factors can reduce the risk of all three conditions, providing an opportunity to simultaneously reduce the burden of age-related brain diseases.
New research published in the Journal of the American Heart Association suggests that even sporadic physical activity can have lasting health benefits, making it easier for people to prioritize their well-being amid busy schedules. The study found that completing 150 minutes of moderate to vigorous physical activity per week, regardles...
Scientists have discovered that early-life cardiac injury in parents can alter heart development and function in offspring, leading to improved cardiac remodeling and increased blood ejection volume. This finding suggests a potential long-term impact on cardiovascular health.
A new study by Mass General Brigham researchers reveals that many eligible patients who receive other preventative screenings are not getting screened for lung cancer. The study found that 65% of those eligible received breast and colorectal cancer screening, a nearly 4-fold higher rate than lung cancer screening.
Researchers from Florida Atlantic University challenge the current aspirin guidelines based on a flawed trial, advocating for healthcare providers to make individual clinical judgments about prescribing aspirin. They stress that patients should consult their primary care provider to balance the benefits of clot prevention against bleed...
A cross-sectional study reveals significant racial disparities in unintentional overdose mortality, with Black individuals facing an increased burden of mortality. Addressing these disparities requires a multifaceted approach targeting social, physical, economic, and policy risk environments.
Scientists at University of Lausanne classify 35 commonly used drugs in Switzerland based on their ecotoxicity. The classification reveals that painkillers like diclofenac and antibiotics like ciprofloxacin have significant consequences for aquatic biodiversity.
The American Heart Association invites communities nationwide to walk together on National Walking Day to break the cycle of sedentary behavior. Regular walking can improve both physical and mental well-being, even in small steps.
A new study published in Nature Communications found that pregnancy may offer protection from developing Long COVID. The research analyzed data on approximately 72,000 pregnant women and 208,000 non-pregnant controls, revealing lower rates of long-term complications related to COVID-19 among pregnant women.
A University of Minnesota Medical School study identified a key heart marker predicting ischemic stroke and dementia, which could lead to improved patient outcomes. The left atrium's ability to stretch was found to be the most accurate predictor.
A new study investigates the safety of excluding pulmonary embolism in high-risk patients based on D-dimer testing. The analysis found that ruling out PE based on a low D-dimer level was safe, with no missed cases.
Swedish researchers have identified 20 genetic variants associated with an increased risk of atherosclerosis, a leading cause of cardiovascular disease. The study used advanced imaging techniques to examine millions of genetic variants, providing new insights into the disease process and potential ways to prevent it.
Hormonal contraceptives initiated immediately after childbirth may increase the risk of developing depression in new mothers. Researchers found that combined oral contraceptives were associated with a higher risk of depression when started earlier postpartum.
A recent NIH-funded study found that rural adults experience higher rates of heart disease and its risk factors compared to urban counterparts. The study revealed that variables such as poverty, education, and access to healthcare do not explain these differences, with lifestyle risk factors like smoking also playing a lesser role.
A recent study found substantial rural-urban disparities in cardiometabolic risk factors and cardiovascular diseases among US adults. Social risk factors are identified as the primary driver of these disparities, with efforts to address socioeconomic conditions in rural communities critical to reducing the gap.
Researchers found females with a history of binge eating start drinking alcohol quicker than males. Increased levels of phosphodiesterase 4B (PDE4B) prevent cooccurrence of binging in both sexes of mice.
The University of Texas at Arlington has launched a new Mobile Simulation Lab to tackle workforce and training challenges in rural areas. The lab, equipped with advanced patient manikins and simulation bays, will provide specialized training for local healthcare providers to expand their expertise.
The SUMMIT trial shows tirzepatide reduces the risk of cardiovascular death or worsening heart failure in patients with obesity, chronic kidney disease, and heart failure, while improving kidney function. Researchers found significant improvements in both patient groups with and without chronic kidney disease.
A new study found that reported tuberculosis diagnoses among incarcerated people in Europe and the Americas plummeted by up to 100% during the pandemic, despite consistent incarceration rates. This reduction was distinct from general population trends, highlighting the need for improved healthcare systems within prisons.
The ALL ALS Consortium has recruited over 300 participants across two studies, ASSESS and PREVENT, aiming to disrupt traditional ALS research by making data and samples available worldwide. The consortium seeks to discover new drug targets and approaches for effective treatments.
Research findings indicate that individuals with a history of antidepressant use have an increased risk of sudden cardiac death, which varies based on age and time of exposure. The study suggests that longer periods of antidepressant exposure are associated with a higher risk of SCD, particularly in older adults.
The rate of cardiac arrests during marathons has remained unchanged, but the chance for survival is twice what it was in the past. The decline in preventable cardiac deaths can be attributed to increased awareness of the risks and availability of emergency services and defibrillators.
Patients with low surgical risk undergoing transcatheter (TAVR) or surgical aortic valve replacement (SAVR) show comparable death, stroke, and reintervention rates at five years. The study found that TAVR is as effective as surgery in improving symptoms, functional class, and overall quality of life.
Patients who received nurse-led follow-up care had a 30% lower rate of cardiovascular death, non-fatal heart attacks, or strokes at five years compared to those receiving standard care. This was achieved through improved lifestyle habits and medication adherence.
A study published in JAMA Cardiology found that finerenone was effective in treating heart failure, regardless of the presence of atrial fibrillation. New-onset atrial fibrillation was linked to a substantially increased risk of adverse outcomes.
A new study found that three months of dual antiplatelet therapy (DAPT) was better than one month for reducing heart attacks, strokes, and other adverse events without increasing bleeding risk in high-risk patients. For low-risk patients, three months of DAPT was comparable to 12 months in reducing adverse events, while being better th...
In an open-label study, patients hospitalized for a serious heart attack who received rivaroxaban or warfarin had similar efficacy and safety outcomes. Rivaroxaban showed comparable results in dissolving left ventricular blood clots at three months follow-up.
A four-year study presented at the American College of Cardiology's Annual Scientific Session found that oral semaglutide reduced cardiovascular death, heart attack, and stroke by 14% compared to a placebo. The drug's benefits are comparable to injectable forms and offer an alternative for patients who prefer not to take injections.
A study found that semaglutide significantly improved maximal walking distance in people with symptomatic peripheral artery disease (PAD) and Type 2 diabetes. Patients taking semaglutide also experienced improvements in symptoms and quality of life compared to those on a placebo.
A study published in JAMA Cardiology found that legislation to reduce sodium in processed food in South Africa is linked to significant declines in blood pressure levels. The reduction in sodium intake has been associated with lower rates of cardiovascular disease mortality and stroke, potentially saving millions of lives globally.