Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
Young adults with higher genetic risk for depression show reduced brain activity in response to rewards and punishments, while sex-dependent neural responses were also observed. This study highlights potential early indicators for depression before symptoms fully manifest.
A new study finds that living in rural areas in the first five years of life may be a risk factor for developing type 1 diabetes, whereas urban environments are associated with lower risk. The research identified significant high-risk clusters in rural areas and low-risk clusters in cities.
A study found that semaglutide and liraglutide use are associated with a higher risk of nonarteritic anterior ischemic optic neuropathy in older patients with type 2 diabetes. The GLP-1 receptor agonists showed varying levels of risk, with liraglutide posing the greatest threat.
A nationwide study found that financial hardship, food insecurity, lack of healthcare access, and other social risk factors increase the risk of long COVID. The RECOVER-Adult cohort study analyzed 3,700 participants and found significant associations between individual-level social risk factors and increased risk of developing long COVID.
Patients with type 2 diabetes experience more severe financial difficulties compared to those without the condition. The study emphasizes the importance of considering patient financial health when treating type 2 diabetes, particularly for vulnerable populations.
The US POINTER trial found that a structured lifestyle intervention of regular exercise, adherence to the MIND diet and social engagement had greater benefits on global cognition compared to an unstructured intervention. The study showed significant cognitive benefit after two years in older adults at elevated risk of Alzheimer disease.
Researchers from FAU's Schmidt College of Medicine recommend using high-potency statins as the primary pharmacologic approach in treating and preventing cardiovascular disease. Lifestyle changes, such as regular physical activity and a healthy diet, are also crucial in reducing cardiovascular risk.
A new study finds that risk-reducing mastectomy is cost-effective for women aged 30-55 with a lifetime breast cancer risk of 35% or higher. The findings have significant clinical implications, suggesting that RRM could expand access to the procedure beyond BRCA1/BRCA2/PALB2 pathogenic variant carriers.
This study found that moderate to vigorous-intensity physical activity declined from early adulthood to midlife, with notable demographic differences. Black women experienced the lowest physical activity across adulthood and highest risk of low physical activity post-CVD.
A contemporary cohort study found a low risk of isolated locoregional recurrence (5.6%) at 10.1 years follow-up for young women diagnosed with breast cancer under 40. Surgical decision-making should not be influenced by concerns about long-term risk.
A new study found that four high-risk population groups - women, adults 45 and older, those living in poverty, and people with metabolic syndrome - are driving the increase. The study also showed that average drinking rates remained unchanged over 20 years before the COVID-19 pandemic.
A cohort study reveals preterm individuals face increased mental health disorders and cardiometabolic issues compared to full-term peers. At age 35, these risks persist despite strong evidence linking preterm birth to long-term health consequences.
A retrospective cohort study found that COVID-19 booster vaccinations significantly protected against severe COVID-19, but uptake was low. Interventions are needed to increase COVID-19 vaccine uptake among high-risk populations with cancer.
A cohort study found that GLP-1RAs like semaglutide and tirzepatide lower risk of dementia, stroke, and all-cause mortality in adults with type 2 diabetes and obesity. The findings suggest potential neuroprotective benefits beyond glycemic control.
This randomized clinical trial found that bedtime dosing of antihypertensive medication improves nocturnal blood pressure control and circadian rhythm without compromising daytime or 24-hour blood pressure. The study suggests potential advantages of bedtime administration for patients with hypertension.
The study reveals that many people are unaware of two crucial facts that can help reduce SIDS deaths: putting babies on their backs to sleep, and avoiding secondhand smoke in the home. The survey found that only 65% know that a baby should be put to sleep on its back, highlighting a need for increased education and awareness.
Residential segregation contributes to lung cancer development in African Americans, highlighting the need for policymakers to address disparities. Structural racism in neighborhoods affects health outcomes, emphasizing the importance of reducing racial gaps in healthcare.
The Families First Coronavirus Response Act led to a significant decrease in Medicaid health insurance loss. The study found that the Act reduced the risk of losing health insurance for individuals enrolled in the Medicaid program.
A new study published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging found that individuals with remitted depression show increased habenula activity and reduced connectivity between the habenula and dopamine-producing regions, suggesting a heightened sensitivity to negative cues. This suggests that even after recove...
Research found that ADHD medication was associated with lower risks of self-harm, unintentional injury, and crime, but the magnitude of these associations decreased as prescription rates rose. The study highlights the need to regularly assess medication use in different patient populations.
Chronic cough is a common symptom in the Asian general adult population, related to risk factors such as age, allergy, smoking, and air pollution. The physical and psychological burden of chronic cough is notable, particularly among older patients or those with comorbidities.
A study identified distinct trajectories of addictive social media, mobile phone, and video game use in US youths, finding links to increased suicidal ideation and worse mental health outcomes. The research suggests that high or increasing addictive screen use may warrant further clinical evaluation and intervention design.
A cohort study suggests severe neonatal morbidity is a significant risk factor for childhood mortality, highlighting the importance of preventing and identifying early signs of severe conditions. Efforts to reduce mortality through infancy and late adolescence may benefit from targeted prevention strategies.
Researchers developed an improved biological ageing clock, LinAge2, that offers doctors a practical way to assess how quickly a person is ageing and what can be done to slow it down. The new algorithm-powered tool outperforms other clinical models in predicting long-term mortality and health outcomes.
A cohort study found that obesity in childhood cancer survivors is linked to an increased risk of developing multiple subsequent neoplasms. Conversely, high levels of physical activity are associated with a reduced risk of these cancers.
The use of GLP-1 receptor agonists among diabetes patients is associated with a higher risk of developing incident neovascular age-related macular degeneration. Further research is needed to understand the underlying mechanisms and trade-offs between benefits and risks.
A large cohort study found significant associations between incarceration and increased risk of death from overdoses, as well as a doubling of individual mortality risk at high county incarceration rates. The findings highlight the need for reforms in criminal justice and public health policies to address these risks.
A nationwide decline in MMR vaccination rates among US children was confirmed by a new dataset, with significant variations observed across states and counties. The study provides valuable insights into factors influencing low vaccination rates and can inform targeted strategies to reduce measles outbreaks.
This novel treatment approach yields better weight loss maintenance and cardiovascular risk outcomes compared to standard-of-care treatment. Patient-delivered lifestyle intervention combined with peer support significantly improves weight loss and reduces cardiovascular risk.
Sustained midlife weight loss was associated with lower chronic disease incidence and decreased all-cause mortality. The study's findings suggest that maintaining a healthy weight during middle age can have long-term health benefits.
A survey of stakeholders in Japan found that incorporating patient voices into assessments of genetic conditions can recalibrate people's ideas about seriousness, shifting perceptions from a tool of societal burden reduction to individual reproductive autonomy. The study emphasizes the need for including patient voices in shaping ethic...
A study found that adults hospitalized for RSV had significantly higher odds of cardiac events compared to those with COVID-19 or influenza. The findings suggest that preexisting cardiovascular risk patients should consider vaccination against respiratory viral infections.
The PREVENT calculator improved estimates of heart attack risk when combined with coronary calcium score. Researchers analyzed nearly 7,000 adults and found that the PREVENT score matched the level of calcium buildup according to the CAC score.
A groundbreaking study reveals how China's 2009 banking deregulation reshaped risk-taking behavior among financial institutions while expanding credit access for small businesses. Deregulation enhanced long-term credit availability in underserved regions, demonstrating financial liberalization's dual role.
A large cohort study found that early antibiotic treatment did not significantly improve outcomes for patients with nonsevere COVID-19. The results argue against routine antibiotic use in this population due to associated risks.
A recent study published in PLOS ONE found that higher maternal selenium levels during pregnancy are associated with a lower risk of streptococcal infections in children. The research tracked over 74,000 mothers and their children to explore potential links between maternal metal exposure and infection risk.
People who sit for more than 14 hours a day may have a higher risk of cardiovascular events or death after treatment for heart attack symptoms. Replacing sedentary time with sleep reduces the risk, according to new research published in Circulation: Cardiovascular Quality and Outcomes.
A new study suggests that controlling eight key health risk factors can significantly reduce premature death risk in people with high blood pressure. By addressing these risk factors, researchers found a 40% lower risk of early death and up to 53% less risk of death due to cardiovascular disease.
Researchers from Mass General Brigham have identified a key predictor of stroke risk among women: brain health scores. Women with higher McCance Brain Care Scores (BCS) had a reduced risk of experiencing a cerebrovascular event, with those with a five-point higher baseline score being 37% less likely to experience an event.
A new COPD diagnostic approach integrates respiratory symptoms, quality of life, spirometry, and CT imaging to accurately classify individuals with the disease. This framework reveals increased risks for mortality, exacerbations, and lung function decline among those classified as having COPD.
A study published in The Lancet Respiratory Medicine found that lung capacity develops in two phases: rapid growth during childhood and slower growth until peak lung function. Lung function starts to decline after the peak age, contrary to previous models. Persistent asthma and smoking affect lung function differently than thought.
A cohort study found that long-term survival was similar among patients with low-risk early-stage cervical carcinoma who underwent simple, modified, or radical hysterectomy. These findings support the use of simple hysterectomy in select patients.
A cross-sectional study found that more than one-third of veterans aged 65-84 who used cannabis in the past 30 days had a cannabis use disorder. Routine health screening for cannabis use is necessary to identify older adults with cannabis use. Frequent and inhaled cannabis use was associated with higher odds of any cannabis use disorder.
A large-scale UK biobank study found that loneliness increases the risk of hearing loss, with a 24% higher risk for lonely individuals compared to non-lonely counterparts. The study also identified distinct pathways through which loneliness contributes to hearing loss, including inflammation and chronic diseases.
Researchers found that only a small fraction of proteins have genetic differences between males and females. Instead, lifestyle, education, and access to resources also contribute to the health gaps experienced by men and women.
A Danish study found that adverse waist-to-height ratio trajectories in childhood are associated with increased cardiometabolic risk at age 10. Children with gradually increasing central obesity showed early signs of metabolic and cardiovascular risk, including elevated blood pressure and insulin resistance.
A new study has discovered a link between delayed puberty and an increased risk of developing type 2 diabetes in boys. According to the research, adolescent boys who experience delayed puberty are 37% more likely to develop type 2 diabetes in early adulthood, regardless of their weight or socio-economic status.
The RSV protein subunit vaccine showed similar efficacy to clinical trials, with diminished immune response in immunocompromised patients. The vaccine was associated with a small increased risk of Guillain-Barré syndrome, but not immune thrombocytopenic purpura.
A multicentre study found that biological ageing, measured by frailty index and telomere length, can predict cardiovascular disease risk more accurately than traditional tools. The study, involving over 14,000 individuals, suggests that incorporating biological age into risk assessments could improve cardiovascular health outcomes.
A cohort study of US veterans found that depression is associated with a higher hazard of incident heart failure after controlling for demographic and cardiovascular risk factors. Depression remains consistent as a risk factor even in low-risk cohorts.
A cohort study of 12,480 mother-offspring pairs found that pre-pregnancy obesity, gestational diabetes, and hypertensive disorders of pregnancy are associated with increased offspring blood pressure. These risk factors may also promote a faster rate of blood pressure change from age 2 to 18 years.
This study finds that teen drivers in older vehicles are more likely to be involved in fatal crashes, highlighting the need for safer vehicles. The study's authors stress the importance of ensuring teens drive newer vehicles equipped with advanced driver assistance technologies.
A study published in Alzheimer's & Dementia found that learning one's Alzheimer's risk can decrease negative emotions like depression and anxiety, but also leads to decreased motivation for maintaining healthy lifestyle changes. Researchers emphasize the importance of personalized disclosure processes to sustain healthy behaviors.
A cohort study found that exposure to conversion therapy increased systolic and diastolic blood pressure, inflammation, and high blood pressure in SGM individuals. The findings highlight the need for stronger public health interventions to ban conversion therapy practices.
A study published in The Lancet Regional Health – Europe found that patients with low household income were more likely to be diagnosed late and receive less effective treatment for liver cancer. This highlights the need for targeted screening in deprived areas to improve early diagnosis and survival rates.
Researchers found that even small doses of high-intensity exercise can reduce the risk of dementia and promote healthy brain aging. The study suggests exercising regularly is crucial for preserving brain health, making it a key prevention measure against cognitive decline.
A new study found that age-, sex-, and race-specific standards could reclassify many thyroid disease diagnoses, with nearly half of subclinical hypothyroid cases being over-diagnosed. The study suggests using these standards to establish more accurate reference intervals for thyroid disease.
A cohort study of 1,787 adults found significant differences in hearing loss prevalence among white male individuals (highest) and Black female individuals (lowest). The study highlights the importance of tailored interventions to reduce hearing loss risk across populations.
A recent study has found that increasing physical activity between the ages of 45 and 65 can help reduce the accumulation of beta-amyloid, a protein linked to Alzheimer's disease. The research, led by ISGlobal, suggests that even minimal amounts of exercise have health benefits for brain health.
A new study reveals a concerning rise in type 2 diabetes among depression inpatients in Beijing from 2005 to 2018. Depression and type 2 diabetes co-occurrence is understudied, but the research found 9.13% of depression patients had T2DM, with significant age, sex, and socioeconomic factors linked to elevated risk.