Articles tagged with Drug Delivery
Researchers at MIT have developed synthetic nanoparticles that can quickly pass into cells without harming them. The key to their approach is a striped structure on the nanoparticles' surface, which allows them to directly penetrate the cell membrane and deliver drugs or imaging agents to the cytosol.
Researchers at USC Information Sciences Institute have developed a method to manufacture miniscule closed containers for precise drug delivery. The new technique uses micro-origami to fold up small shapes, which can be used to create 'voxels' - tiny volume-enclosing structures.
Researchers have developed a unique nanoparticle that can safely deliver a compound to the eye, blocking an enzyme that contributes to glaucoma. This non-toxic tool offers high penetration rates and little patient discomfort, making it a promising treatment option.
Researchers at Ohio State University have developed a new method to create polymer rings that can encapsulate and release specific molecules at specific times. The technique has the potential to be used in medicine, particularly in drug delivery and antibiotic development.
A study published in the Archives of Internal Medicine found that women were less likely to benefit from hospitals' quality-improvement measures and received fewer drugs and lifestyle counseling after a heart attack. This disparity led to a higher risk of death within a year, despite overall improved care for both men and women.
Researchers have discovered that certain proteins in the amniotic membranes can fuel an inflammatory response, leading to preterm labor. The study aims to develop a chemical test to identify effective drugs and block the TLRs to stop early labor.
A pharmacist has been awarded a $500,000 MacArthur grant to develop and implement safe medication practices, potentially saving up to 98,000 lives per year. The project aims to educate the healthcare community on medication safety, following a range of successful initiatives.
Scientists have developed a novel structure made from cell components that can assemble into nanotubes with controllable open or closed states. This innovation has the potential to deliver drugs or genes where they would be most effective, using the natural properties of cells similar to skin and bone.
The new process, developed by Michael Wong and his team, involves mixing polymer, salt, and tiny silica particles to create hollow spheres that can encapsulate drugs, flavor compounds, and other molecular cargo. The microcapsules have potential applications in drug delivery, medical imaging, and enzyme protection.
The report has had a positive impact on improving patient safety by changing healthcare views, enlisting support from stakeholders, and altering practices. Clinical effectiveness of safe practices implemented in hospitals show promising results, including reduced medical errors, adverse drug events, and cardiac arrests.
A randomized controlled trial found that combining cognitive-behavioral therapy (CBT) with medication significantly improved treatment outcomes for patients with panic disorder. Patients receiving CBT and medication had higher remission rates and greater improvements in mental health functioning compared to those receiving usual care.
Chemists in Australia have created a molecule called the 'superbowl' that can carry large molecules of medicinal value, including painkillers and chemotherapy drugs, to specific areas of the body. The molecule shows promise for precision drug delivery and may one day improve medical treatments and save lives.
Researchers found that heat can alter drug dosage and appearance, putting patients with respiratory conditions at risk. The study advises patients to inspect mail-order medications before consumption and avoid exposing them to extreme temperatures.
The SonoPrep device uses ultrasonic energy to make skin more permeable, allowing for painless treatment with lidocaine cream, reducing wait time from one hour to five minutes. The technology has potential applications in various medical procedures and may lead to further innovations like glucose-sensing devices.
University of Houston College of Pharmacy students took first through fourth place in the Texas Pharmacy Association competition with projects on asthma management, community wellness, and medication labeling. The UH College of Pharmacy won for having the highest percentage of student body members in the TPA-ASP.
Engineers at Ohio State University used compressed carbon dioxide to embed protein molecules in plastic, creating a process for developing implantable drugs. The technology could be used to release medicines into the body, improving medical treatment and reducing environmental impact.
Researchers at NIST have developed a new method for producing uniform, self-assembled nanocells using micrometer-size channels. These nanocells can be controlled to specific sizes and are ideal for encapsulating medicine, leading to more accurate drug delivery.
Researchers at UCSD have developed a way to transfer the optical properties of silicon sensors to plastic, creating flexible and biocompatible devices that can monitor drug delivery, joint strain, or healing. This technology could lead to non-invasive monitoring of implantable devices.
Researchers at Virginia Tech have developed a new cryptand compound that forms stronger non-covalent bonds than traditional host crown ethers. The improved association constants enhance the recognition and attraction between host and guest molecules, paving the way for potential applications in medicine.
Researchers have developed contact lenses that can dispense prescription drugs directly to the eye, reducing the risk of side effects associated with traditional eye drops. The new technology uses nanoparticles to encapsulate drugs in a matrix, allowing for controlled release over an extended period.
A study of Medicare prescription benefit plans found that higher copayments reduce the use of brand-name drugs and lower overall plan costs, but also increase enrollee out-of-pocket expenses. The research suggests that combining cost-sharing strategies with other cost-containment mechanisms can help balance these competing effects.
Researchers are developing non-invasive methods for delivering therapies, such as patches, inhalers, and ultrasound, to overcome limitations of traditional drug delivery. Tissue engineering also holds promise for growing new organs and tissues using cells and polymers, offering potential solutions for diseases like diabetes and paralysis.
A new Medicines Information Helpline has been launched in the UK to provide independent expert advice on medicines for patients with Parkinson's disease. The helpline, staffed by experienced pharmacists, aims to address the need for reliable information on medication management for this growing population.
A new implantable device has been designed to deliver anti-psychotic medication for up to a year, potentially relieving patients of psychosis and social instability. The device, made of biodegradable polymers, is surgically implanted under the skin and releases medication into the bloodstream at a specific rate.
Pregnant women infected with HIV can reduce the risk of transmitting the virus to their infants by about 50 percent if they deliver by elective cesarean section before labor and membranes rupture. The study found that c-sections cut mother-to-child HIV transmission by at least 50 percent.
Researchers at UT Southwestern Medical Center found that walking during the first stage of labor had no impact on labor duration, pain management, or infant outcomes. Women who walked showed similar results to those who rested in bed, with most indicating they would walk again in future labors.