Articles tagged with Type 1 Diabetes
Researchers found that DiaPep277 modulates the immune system to prevent autoimmune diabetes progression. The study showed significant increases in C-peptide levels and reductions in insulin requirements among patients receiving DiaPep277.
A phase II study found that DiaPep277 treatment maintained insulin production in patients with early type 1 diabetes. The treatment also reduced the need for insulin therapy and altered immune response patterns.
A study of 12,055 women found that children with recommended vitamin D supplements had a reduced risk of developing type 1 diabetes. The researchers suggest that health workers ensure all infants receive adequate vitamin D to prevent the condition.
Researchers found significant susceptibility for thyroid autoimmune disorders and Type 1 diabetes mellitus associated with DQ2 alleles, primarily transmitted from fathers to affected daughters. Hormonal factors may also regulate this interaction, as observed in the transmission of disease to pre- and postpubertal individuals.
The establishment of these centers brings together unique research expertise to perfect islet cell isolation and availability techniques. The centers aim to improve cellular viability, function, and shipping procedures for patients with type 1 diabetes.
A USC study found that teenagers and young adults with type 1 diabetes have a higher risk of atherosclerosis, or plaque buildup in their arteries. The study suggests that physicians should monitor lipid levels in these patients, even at an early age, to prevent cardiovascular problems.
A common treatment for diabetic crisis in children may contribute to a rare but often-fatal complication known as cerebral edema. Two simple blood test measurements can help predict which patients are at greatest danger of developing the potentially deadly complication.
Recent advances in diabetes treatment have improved blood sugar control, allowing patients to dodge complications until late life. New drug therapies, including metformin and insulin analogs, have enhanced treatment possibilities.
Scientists have found a novel gene, JM2, that causes an inherited form of type 1 diabetes and autoimmunity in boys. The mutations affect the protein's function, leading to hyperactive immune cells that destroy islet cells, resulting in diabetes and allergies.
A team of Type 1 diabetic athletes, including University of North Carolina M.D.-Ph.D. candidate Jeremy Ackerman, will climb Cerro Aconcagua in Argentina to raise awareness about diabetes and conduct scientific research on the effects of altitude on diabetics.
The DIRECT programme aims to establish whether candesartan cilexetil can prevent and treat diabetic retinopathy. The trial will investigate the effect of RAS blockade on diabetic patients with and without retinopathy.
Researchers found a strong association between high calcium scores and heart disease in people with Type 1 diabetes. The study suggests that a non-invasive heart scan may identify patients at high risk for heart disease earlier, allowing for potential interventions to lower their risk.
The National Institutes of Health (NIH) is launching a new clinical trial to test a promising transplant therapy for type 1 diabetes. The Edmonton protocol involves transplanting insulin-producing pancreas cells and aims to induce immune tolerance, allowing people with the condition to stop relying on insulin injections.
Researchers found that Avandia improves beta cell function, as measured by proinsulin to insulin ratio, indicating potential benefits for long-term glycemic control and disease progression. The study's results support the use of Avandia in type 2 diabetes treatment and suggest its potential to delay disease progression.
The JDF Center aims to develop new gene therapy techniques to increase islet cell supply for transplantation and protect transplanted cells from immune system attack. The center will focus on making islet cell transplants viable for young patients with Type 1 Diabetes.
A study found that young women with diseases requiring strict diets may experience unhealthy eating attitudes and behaviors, which can increase the risk of vascular complications and brain damage. The research highlights the need for clinicians to monitor signs of disordered eating in patients with chronic diseases.
Researchers found that diabetics under specialist care had significantly lower blood glucose levels and higher participation in self-care practices. The effect was particularly notable among patients with lower education levels.
Researchers have developed a new and painless way to measure glucose levels in diabetics using low-frequency ultrasound. The method, described in a recent study, involves making the skin permeable with ultrasound waves, allowing glucose to cross the skin and be measured continuously for up to 12 hours.
Researchers developed a reliable blood test to diagnose diabetes in children at an early stage, allowing for prediction of the condition with a reliability of 50%. The test measures concentration of islet antibodies in a child's blood and combines it with DNA testing for hereditary susceptibility.
A University of Pittsburgh study has found that depressive symptoms are a significant risk factor for coronary heart disease among people with Type 1 diabetes. The study's results also suggest that blood sugar levels do not strongly predict the likelihood of this complication.
The UofA research team is working to prevent rejection of transplanted islet cells, allowing diabetics to become insulin-free. Researchers are also developing procedures for transplanting islet cells before physical complications set in.
Researchers found slight memory impairment in children on intensive diabetes therapy, with a three-fold higher rate of severe hypoglycemic incidents compared to conventional therapy. The study suggests potential long-term cognitive consequences related to repeated hypoglycemic episodes.
A recent study found that nearly half of people with type 2 diabetes stop taking their oral anti-diabetic drugs (OADs), leading to a higher risk of complications such as blindness, amputation, and cardiovascular problems. The study revealed that individuals who discontinued treatment were almost three times more likely to die than thos...
Research highlights potential causes of autoimmune diseases, including prenatal exposure to environmental chemicals and certain dietary factors. Studies also explore links between ultraviolet radiation, stress, and exposure to heavy metals.
Studies suggest that involving individuals with diabetes in their care can improve quality of life and reduce complications. The results highlight the importance of patient education and empowering patients to make informed treatment choices.
A pan-European study found that type 2 diabetes in Europe is a significant healthcare burden, with total costs exceeding €29 billion and average individual costs more than double those of the general population. Preventing long-term complications through urgent action is crucial to reducing these costs.
Researchers found that resistant mice have higher levels of antioxidant enzymes, which help protect against pancreatic beta-cell destruction. The study suggests a single gene may be responsible for the genetic resistance, and identifying it could lead to therapies to boost natural defenses against diabetes.
Researchers at the University of Pittsburgh found that HbA1 levels predict mortality from coronary artery disease in women with Type 1 diabetes. However, this association was not seen in men with the same condition. The study analyzed data from over 600 subjects and suggests a gender-specific link between hyperglycemia and CAD risk.
Harvard and UF researchers identified a component of the human immune system that appears to prevent type 1 diabetes in a group of people at high risk. The protein interleukin-4 (IL-4) is produced in large amounts in these individuals and may suppress the arm of the immune system involved in the destruction of insulin-producing cells.