Researchers at Tel Aviv University discover a simple blood test can predict diabetes risk up to five years before symptoms appear. The test uses A1c levels to identify high-risk patients, who may benefit from earlier diagnosis and treatment.
A study published in the Journal of the American Medical Association found that maintaining higher blood glucose levels than recommended does not increase the risk of diabetes complications. People with MODY, a genetic change leading to elevated blood glucose from birth, had the same risk as their normal relatives.
A new study published in PLOS ONE suggests that a Mediterranean diet without breakfast, but with a large meal at lunch, may be the most beneficial for patients with diabetes. The study found that this diet approach reduced blood glucose levels and triglycerides compared to low-fat and low-carbohydrate diets.
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Research published in Diabetologia shows that pre-existing diabetes in pregnant women significantly increases the risk of fetal and infant death. The study found a four-and-a-half times higher risk of fetal death and an almost doubling of infant mortality compared to women without diabetes.
A new study finds that high blood glucose levels before and after surgery significantly increase the risk of wound-related complications in diabetic patients. Tight control of glucose levels during surgery is recommended to reduce these risks.
Joslin scientists found that salsalate effectively lowers blood glucose and improves glycemic control in type 2 diabetes. The study involved 286 participants with inadequately controlled diabetes, who showed significant reductions in hemoglobin A1c levels and fasting glucose concentration.
A study found that exercise-induced improvements in glycemic control are dependent on pre-training blood glucose levels and type 2 diabetes status. Moderate-intensity aerobic exercise improved body weight, body fat, fasting plasma glucose, and 2-hour oral glucose tolerance test results.
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The predictive Hypoglycemia-Hyperglycemia Minimizer (HHM) System demonstrated that it can maintain safe glucose levels overnight, with participants spending over 90% of the time within a target range. The system showed encouraging performance in controlling blood glucose values during the critical nighttime period.
Leading diabetes expert argues that 'Type 2 diabetes' is a category error, implying an entity that doesn't exist. This mislabeling has led to sub-optimal treatment for patients. Professor Edwin Gale proposes replacing the term with 'idiopathic hyperglycaemia', emphasizing individualized treatments based on varied causes.
The American College of Physicians recommends targeting a blood glucose level of 140-200 mg/dL for surgical and medical intensive care unit patients when using intensive insulin therapy. The guidelines aim to balance the benefits and harms of hyperglycemia management in hospitalized patients.
Researchers found that a restrictive diet following bariatric surgery leads to rapid improvements in blood glucose levels. The study's findings suggest that controlling food intake is key to successful diabetes remission.
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A community-based diabetes prevention program, led by health workers, successfully reduced blood glucose levels and improved insulin sensitivity in overweight participants with prediabetes. The study replicated the results of the Diabetes Prevention Project, demonstrating a significant reduction in diabetes risk.
Studies have shown that the autonomic nervous system plays a crucial role in regulating insulin secretion from beta cells in the pancreas. Researchers at Karolinska Institutet successfully grafted beta cells into mice eyes to study their function, revealing how the autonomic nervous system influences blood glucose levels.
Researchers found that epigallocatechin-3-gallate, a compound in green tea, can reduce blood glucose levels when combined with starchy foods. This suggests that drinking green tea with meals containing starch may help control typical blood sugar increases.
Researchers found that blood glucose tracking apps can pose challenges for older adults due to declining vision, memory, and motor skills. The apps' design problems include small text, poor color contrast, and font sizes that decrease when text exceeds one line.
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New research from the University of Copenhagen found that even slightly higher blood glucose levels increase the risk of ischemic heart disease. A study of over 80,000 participants revealed a 69% increase in risk with just 1 mmol above normal levels.
A study in mice found a connection between obesity and elevated blood sugar levels, potentially leading to new treatments for Type 2 diabetes. The research suggests that targeting glucagon, a pancreas-produced hormone, may be an effective pathway to lowering sugar levels.
A clinical study demonstrates the effectiveness of an automated insulin dosage titration system in improving blood glucose control and reducing hypoglycemic events. The system, developed by Hygieia, Inc., automatically updates insulin dosage for patients with type 2 or type 1 diabetes, leading to improved glycemic targets.
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A new study aims to determine whether intravenous insulin delivery is more effective than standard shots in improving stroke outcomes. Researchers hope to find ways to lower high blood glucose levels quickly and safely after a stroke, which can worsen brain damage.
A study published in the Journal of Nutrition found that genetically-determined differences in salivary amylase activity influence blood glucose levels after starch consumption. Individuals with high salivary amylase activity tend to have lower blood glucose levels and may be better adapted to eat starch-rich foods.
Researchers found dapagliflozin effective as an add-on for type 2 diabetes treatment, despite long-term safety data limitations and increased hypoglycemia risk. Peer mentoring improved glucose control among African American veterans through behavioral interventions. However, the use of antiplatelet therapy in patients with chronic kidn...
A new study of three diets with obese children shows that all diets are effective in managing weight. The reduced glycemic load diet may be the most promising approach for pediatric weight management.
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A recent study published in The Journal of Infectious Diseases found a significant association between H. pylori bacteria and elevated glycosylated hemoglobin (HbA1c) levels in adults, particularly those with obesity. This link suggests that the bacteria may play a role in the development of type 2 diabetes.
A clinical practice guideline recommends continuous glucose monitoring for type 1 diabetes patients who can use devices daily, while also limiting risks of hypoglycemia. The guideline aims to improve glycemic control and reduce hypoglycemia risk in patients with type 1 and type 2 diabetes.
A simple finger prick test during routine eye exams at high street opticians can identify millions of people with undiagnosed Type 2 diabetes. This could lead to better disease management and cost savings for the NHS.
Research found no clear picture on risk of death and cardiovascular disease with intense vs conventional glucose control. Lower intensity levels may reduce small vessel damage, but increased risk of low blood sugar and death with more intensive control.
A recent study found that higher muscle mass is associated with better insulin sensitivity and lower risk of pre- or overt diabetes. Building muscle may be a key factor in improving metabolic health, particularly for overweight individuals who struggle to lose weight.
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A study identified blood glucose levels that predict the 10-year risk of retinopathy. Individuals with higher fasting plasma glucose and HbA1c levels were more likely to develop eye-related complications.
A study by USDA researchers suggests that a water-soluble cinnamon extract can improve antioxidant variables and decrease fasting glucose levels in people with prediabetes. The extract showed significant improvements, with a correlation between antioxidant status and blood glucose reductions.
A York University study reveals that type 1 diabetes can affect athletic performance, but it can be managed through proper blood sugar management. The research found that sport skill performance was highest when blood glucose values were in a normal range.
A new diabetes drug, dapagliflozin, has been shown to improve blood sugar control in patients who have inadequate control with metformin. The drug acts independently of insulin, promotes excretion of glucose in the urine, and is associated with weight loss and low risk of hypoglycaemia.
Researchers found significant differences in hemoglobin A1c response to blood glucose between African-American and Caucasian children with diabetes. The study suggests that doctors may be misinformed about blood glucose levels in African-American patients, leading to life-threatening hypoglycemia and increased complications.
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Researchers found that chokeberry extract reduced body weight, improved blood glucose regulation, and decreased inflammation in prediabetic rats. The study suggests that chokeberry's antioxidant properties may help modulate genes associated with adipose tissue growth and inflammatory pathways.
Consuming foods with high glycemic index increases the risk of coronary heart disease in women due to higher levels of blood glucose and triglycerides. A study found that a diet rich in high-glycemic index carbohydrates, rather than overall carbohydrate intake, is associated with greater risk of heart disease in women.
Research finds that intensive glucose control can lower blood glucose too far, increasing mortality risk in patients with type 2 diabetes. The study suggests that blood glucose level targets should have both upper and lower limits to minimize the risk of hypoglycemia.
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A study found that individuals with higher blood glucose levels tend to be more future-oriented, while those with lower glucose levels focus on the present. Fluctuations in blood sugar may affect our decisions for immediate versus delayed rewards.
Two studies find that routine self-monitoring of blood glucose levels by people with type 2 diabetes who are not taking insulin is an ineffective use of health-care resources due to significant cost of test strips. Expenditures associated with blood glucose self-monitoring in Canada are projected to exceed $1 billion.
A recent study found that liraglutide significantly improves glycaemic control compared to exenatide, while also being better tolerated. Liraglutide reduces HbA1c levels by 1.12%, compared to 0.79% for exenatide, and promotes similar weight loss.
Researchers at Joslin Diabetes Center have identified a crucial link between insulin and glucagon levels. The study suggests that targeting insulin receptors or proteins in alpha cells could lead to the development of a new treatment for diabetes, particularly for type 1 patients who are at risk of hypoglycemia.
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A new study published in The New England Journal of Medicine suggests that intensively lowering blood glucose in critically ill patients increases the risk of death by 10%. The research, which followed over 6,000 ICU patients, found that targeting very low levels of blood glucose is not safe.
A major international diabetes study of over 52,000 patients from eight countries found that using biphasic BIAsp 30 insulin resulted in significant clinical improvements and greater patient satisfaction. The study showed a 53% reduction in blood glucose levels below seven percent, with major hypoglycaemia incidents falling by 94%.
A randomized controlled trial studied 700 critically ill patients aged under one year and 1-16 years, finding that intensive insulin treatment reduced mortality by 3% and intensive care stay by 5.5 days compared to conventional insulin treatment.
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Researchers investigate the effect of high blood sugar on the immune system in hopes of improving islet cell transplant success rates. High blood glucose levels can temporarily shift the balance between effector and regulatory T cells, giving advantage to regulatory cells that suppress attacks.
Researchers at Beth Israel Deaconess Medical Center discovered that the AAT protein can restore normal blood glucose levels in a mouse model of Type 1 diabetes. The study suggests that inflammation plays a key role in the disease and provides evidence for using the protein as an alternative treatment option.
Studies show mixed results on blood glucose control and micro-vascular disease prevention, while oral drugs like metformin offer some benefits. Tight insulin control has limited proven success in reducing complications, emphasizing the need for longer-term studies.
A study published in Archives of Neurology found that individuals with mild cognitive impairment are more likely to develop diabetes, have longer durations of diabetes, and experience greater severity. Poor blood glucose control over time may lead to neuronal damage, contributing to cognitive impairment.
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A study of nearly 9,000 patients found that inadequate blood sugar control increases the risk of death and major complications after heart surgery, affecting both diabetic and non-diabetic patients. The research suggests that strict protocols for active blood sugar control are necessary to improve patient outcomes.
A collection of state-of-the-art reports highlights the benefits of self-monitoring blood glucose (SMBG) in achieving improved glucose control. SMBG has been shown to significantly improve glucose control, complements A1C results, and guides patient self-management of diabetes at home.
A randomized controlled trial found that early intensive insulin therapy improved blood glucose control and β-cell function in patients with newly diagnosed type 2 diabetes. The treatment, which included continuous subcutaneous insulin infusion or multiple daily insulin injections, resulted in higher remission rates and prolonged glyc...
Critically ill patients with wide glycemic variability were more likely to die and develop nosocomial infections compared to those with low variability. The study identified age, previous diabetes history, and insulin control as predictors of high variability.
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A genetic breakthrough explains dangerously high blood glucose levels in healthy individuals by identifying a DNA sequence that controls variability. This discovery holds out hope for 'personalized medicine' and may lead to customized treatment based on an individual's unique genetic structure.
Two studies suggest that Diabetinol, a natural citrus supplement, improves blood glucose numbers and LDL-cholesterol levels in people with type 2 diabetes. The supplement shows promise in lowering blood glucose levels after meals and improving heart health, potentially reducing diabetic complications.
Regular Tai Chi Chuan exercise improves T cell helper function in patients with type 2 diabetes by increasing T-bet transcription factor and IL-12 production, suggesting a potential therapeutic effect. The study also found improved glycemic control, reduced inflammation, and enhanced immune response.
A study by the American Heart Association found that minority and financially vulnerable adults with insulin-treated diabetes are less likely to monitor their blood glucose levels. The disparities were greatest for low-income Hispanics, with significantly lower rates of daily self-monitoring compared to whites.
Researchers analyzed over 3.6 million patient records to find thousands of cases of probable undiagnosed diabetes in the UK. The study suggests that tens of thousands of people may be at risk of diabetes and require further assessment.
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A new study is providing community pharmacists with education and advice on controlling blood glucose levels through individual glucose meter uploads. The project aims to determine whether lifestyle advice from pharmacists improves glycaemic control and potentially reduces the burden of Type 2 Diabetes on healthcare systems.
A study published in JCI Journals found that glucose reperfusion triggers more extensive neuronal death in hypoglycemic mice than prolonged hypoglycemia itself. Gradual increase of blood glucose levels may be a better approach to treat individuals in hypoglycemic coma, but the findings are subject to further clarification.
A randomized controlled trial shows that low-dose hydrocortisone continuous infusion minimizes hyperglycaemic episodes and serious adverse events in critically ill patients with sepsis. Continuous infusion also reduces nurses' workload by requiring fewer insulin dose adjustments.
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A new study aims to improve diabetes management by linking patients' glucose levels to their pharmacists. Half of the participants will share their data with their pharmacist for lifestyle advice, while the other half will manage it themselves.
A recent study found that high blood glucose is responsible for approximately 2.2 million cardiovascular deaths and 1.5 million ischaemic heart disease deaths worldwide. The findings highlight the significant burden of high blood glucose on mortality from these conditions.