Articles tagged with Radiation
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A study of 7807 children found no increased risk of brain tumours, leukemia, or lymphoma after a single CT scan. However, exposure to 4 or more scans before adulthood significantly increases the risk of intracranial tumours, leukemia, and non-Hodgkin lymphoma
Researchers found that participants with lower written health literacy experienced longer delays in initiating postoperative radiation therapy. The study controlled for demographic and clinical factors, highlighting the importance of health literacy in cancer care.
Dr. Erik K. Paulson, MD, chair of Duke University's radiology department, has been elected as the 123rd President of ARRS for a one-year term starting April 2023. He succeeds Gary J. Whitman, who served from 2022 to 2023.
A study published in the journal Cancer found that long-term pancreatic cancer survivors have a robust immune response and enriched gut microbiome species, including Faecalibacterium prausnitzii. The research suggests that these bacterial species may promote immune response to pancreas cancer.
Researchers from China have identified inosine as a potential broad-spectrum anti-inflammatory agent that improves survival in mice infected with SARS-CoV-2. The study also highlights TBK1 as a promising target for inhibiting cytokine storms and mitigating acute inflammatory lung injury.
Researchers found that senescence-associated exosomes (SA-EXOs) from MSCs induce fibrosis and activate invasive characteristics in neighboring cells via the TGF-β pathway. SA-EXOs play a large role in cancer-related fibrosis, and their unique miRNA content influences myofibroblast phenotypes.
A research team at City University of Hong Kong invented a tunable terahertz meta-device that can control the radiation direction and coverage area of THz beams. The device allows for signal delivery to specific users or detectors and has flexibility to adjust the propagating direction, as needed.
A team of scientists developed a new model for high-power terahertz emissions from laser pulses, observing multi-mJ THz emission from 100-TW-laser-driven LWFA. The correlation between electron beam properties and THz output energy reveals that low-energy but high-charge electrons can produce stronger terahertz radiation.
A new study published in the International Journal of Radiation Oncology, Biology and Physics found that stereotactic body radiotherapy (SBRT) is an effective treatment for early stage lung neuroendocrine tumors. The three-, six- and nine-year local control rates with SBRT were 97%, 91% and 91%, respectively.
Researchers discovered that radiation damage to paternal DNA is passed on to offspring through a highly error-prone repair mechanism. This leads to structural changes in the paternal chromosomes and causes developmental defects. Histone proteins play a crucial role in shielding damaged chromosomes from accurate repair.
Researchers at KAUST have developed acoustic tweezers that use spinning sound waves to manipulate ultrasmall objects with precision. This technology has the potential to enable precise control of submillimeter objects in opaque media, such as soft biological tissues.
A new space-time coding antenna developed at City University of Hong Kong enables manipulation of beam direction, frequency, and amplitude for improved user flexibility in 6G wireless communications. The antenna relies on software control and combines research advances in leaky-wave antennas and space-time coding techniques.
For adrenal lesions evaluated by single-phase dual-energy CT, fat fraction had significantly higher sensitivity than virtual noncontrast attenuation at both clinically optimal threshold and traditional ≤10 HU threshold. Fat fraction-derived metrics can help definitively diagnose incidental adrenal lesions as adenomas.
Researchers at CU Anschutz Medical Campus have identified a less invasive way to treat HPV-unrelated head and neck squamous cell carcinomas by combining radiation with immunotherapy. The approach resulted in remarkable success rates, including 75% of patients experiencing major pathological responses or complete responses.
Researchers at CU Anschutz Medical Campus found that irradiating only select lymph nodes near a tumor can significantly decrease cancer recurrence and improve patient outcomes. This approach eliminates the source of immune cells for immunotherapy to work on, but preserving long-term systemic immune response.
A Phase III trial found that hypo-fractionated whole breast irradiation (WBI) with concurrent boost is not inferior to conventional WBI with a sequential boost following lumpectomy in patients with high-risk, early-stage breast cancer. The study showed comparable effectiveness and toxicity outcomes between the two treatment options.
A randomized phase III trial found that hypofractionated whole-breast radiation with concurrent boost is comparable to six weeks of treatment for patients with higher-risk disease, reducing tumor recurrence by 20-30%. The three-week course was non-inferior to the longer treatment in terms of tumor recurrence and cosmetic outcomes.
In a first-in-human trial, FLASH radiation treatment was found safe and effective for pain relief in patients with bone metastases. The study showed significant pain relief in 7 out of 10 patients, with minimal side effects.
A phase III clinical trial confirms the safety and efficacy of a moderately shortened course of radiation therapy for men with high-risk prostate cancer. The study found no significant differences in survival rates, side effects, or recurrence between 5-week and 8-week radiation therapy.
A phase II trial suggests that radiation can reduce painful complications and hospitalizations, and possibly extend overall survival in patients with advanced cancers. The study found that treating asymptomatic lesions with radiation reduced skeletal-related events and extended overall survival compared to those who received no radiation.
A new study found that sexual side effects of cancer treatment are discussed less frequently with female patients, who are asked about their sexual health 1 in 10 times, compared to 9 in 10 men. The disparity is also observed in clinical trials nationwide.
Researchers compare Monte Carlo simulations and Loevinger formula for beta radiation dosimetry in cancer treatment, finding the latter to be a quick yet accurate method. The study suggests using the Loevinger formula as a basis for dosimetry software in simple geometries.
UCF researchers have designed a cerium oxide nanoparticle to protect bones against radiation damage from cancer therapy. The treatment also improves bone regeneration and kills cancer cells, reducing the risk of bone fractures and tissue damage.
A recent study published in Advances in Atmospheric Sciences identifies compensating errors in widely used climate model protocols, known as CMIP6. The researchers analyzed five CMIP6 models and found large uncertainties in cloud microphysical properties, including cloud fraction, liquid water path, and droplet effective radius.
Scientists from Göttingen and Lausanne successfully created electron-photon pairs in an electron microscope for the first time. This breakthrough enables researchers to harness free electrons and photons in a controlled manner.
Cancer patients in rural areas experience higher mortality rates and are more likely to miss radiation appointments, leading to poorer overall survival. The study suggests that targeted support programs like patient navigation can help reduce disparities in cancer care.
A study published in the American Journal of Roentgenology found that combining deep-learning reconstruction with a subtraction technique yielded optimal diagnostic performance for detecting in-stent restenosis by coronary CT angiography. This approach reduced radiation exposure while maintaining high image quality.
A research group from Tokyo University of Science has discovered molecular features that govern the filling process at nanoscales, enabling finer resolutions in ultraviolet nanoimprint lithography. The findings provide valuable insights for guiding the selection and design of optimized resists for sub-10 nm resolution.
Researchers investigated radiation exposure among health professionals performing structural heart interventions, revealing higher doses for echocardiographers and cardiologists compared to sonographers. The study highlights the need for safer procedures and protective measures to mitigate radiation risks.
Scientists at Max Born Institute create novel method to probe magnetic thin film systems, identifying heat injection from platinum layer as cause of magnetization changes. The approach allows femtosecond temporal and nanometer spatial resolution, paving way for studying ultrafast magnetism and device-relevant geometries.
A series of FQXi-funded experiments deep under the Italian mountains failed to find evidence in support of a gravity-related quantum collapse model, undermining the feasibility of this explanation for consciousness. The team used an extremely sensitive cylindrical detector and reported no spontaneous radiation signals after running the...
A meta-analysis published in The Lancet Oncology suggests that targeted radiation therapy, which spares healthy brain tissue, is equitable to whole brain radiation therapy for patients with small cell lung cancer and brain metastases. This approach may improve their care experience with fewer negative cognitive consequences.
Concentrated solar power (CSP) plants use wet cooling methods to dissipate waste heat, but this can lead to significant water loss. A new study developed a radiative cooling system with cold storage that reduces water consumption by up to 85% in hot regions.
A clinical trial found that adding immunotherapy to standard treatment increased the likelihood of complete tumor eradication in patients with high PD-L1 expression. The combination could become a new standard of care if confirmed in larger trials.
The American Journal of Roentgenology has published best practices for managing an iodinated contrast media (ICM) shortage in radiology practices. To mitigate the shortage, practice leaders should prioritize examination findings and reduce overall ICM usage.
The new ASTRO guideline provides guidance on radiation therapy for brain metastases, including evidence-based recommendations for multidisciplinary planning and delivery of advanced techniques to manage intact and resected brain tumors. The guideline aims to improve quality of life and outcomes for patients with brain metastases.
Dr. Gary J. Whitman, MD of the University of Texas MD Anderson Cancer Center, has been appointed as the 122nd President of the American Roentgen Ray Society (ARRS). He succeeds Jonathan Kruskal, MD, PhD, and will serve for the next year.
Research suggests that EMFs can cause Alzheimer's disease by building up calcium levels in brain cells. This increase leads to changes in the brain, which develop conditions for Alzheimer's. The study highlights the importance of reducing EMF exposure to prevent or delay the onset of Alzheimer's.
Researchers create high-power laser and foam ball to simulate supernova remnants and observe compression of molecular cloud material. This experiment demonstrates the potential for laboratory astrophysics to understand star formation mechanisms.
Raising awareness about cardiac radiation exposure reduced the number of patients receiving high heart doses in lung cancer patients. The study found that standardized cardiac dose constraints improved patient care without minimizing tumor treatment or increasing dosage to other at-risk organs.
Researchers found that adjuvant radiation therapy compared to early salvage therapy reduced mortality risk in men with pN1 prostate cancer. The study, published in the Journal of Clinical Oncology, showed a 8% decrease in mortality for each additional positive pelvic lymph node found at surgery.
A CHOP-led study found bortezomib significantly improved overall survival in children and young adults with newly diagnosed T-cell lymphoblastic lymphoma. The trial also showed that intensifying the chemotherapy regimen allowed for elimination of radiation in nearly all patients, resulting in excellent outcomes.
Researchers have leveraged quantum information theory techniques to amplify entanglement in the Hawking effect, a process previously difficult to test due to the faint nature of Hawking radiation. By illuminating event horizons with appropriately chosen quantum states, they can tunably stimulate entanglement production.
Researchers created two types of hydrogenous-rich composites for shielding space radiation, which showed higher shielding abilities than traditional aluminum. The simulations also revealed that these new composites can reduce the mass needed for shielding by up to 77% when the thickness is larger than 10 g/cm².
A new study found that traditional Chinese medicine Shengmai Yin increases the sensitivity of cancer cells to radiation, reducing radioresistance. By altering DNA methylation status, SMY enhances the efficacy of radiation therapy and reduces side effects.
A study published in Nature Cancer has found that tissue damage caused by radiation can facilitate the spread of cancer, with neutrophils playing a key role. The researchers used mice to test the effect of high doses of radiation on healthy lung tissue and found that secondary tumours formed more easily in damaged lungs.
A new study highlights alternative treatment options that consider a patient's likelihood of recovery and quality of life. Total Definitive Treatment (TDT) is an approach that combines chemotherapy, radiation therapy, and close monitoring to potentially cure patients without surgery.
Patients with severe coronary artery calcium have a significantly increased risk of major adverse cardiovascular events during thoracic radiation therapy for non-small cell lung cancer. The study found that patients with severe coronary artery calcium had a 21.4 times increased risk compared to those with no coronary artery calcium.
A genome study found significant variation in human ribosomal RNA (rRNA) genes based on geographic ancestry, particularly in the 28S rRNA segment. This discovery suggests that these variants may be important for understanding cancer development and functionally assessing their impact on ribosome functions.
A research team from the University of Jena has made an important breakthrough in generating high-energy proton radiation using laser-plasma interaction. By precisely adjusting parameters such as foil thickness, laser focusing, and pulse duration, they have achieved a maximum energy yield that could enable the development of smaller an...
A new meta-analysis of randomized clinical trials found that adding androgen deprivation therapy (ADT) to definitive radiotherapy prevents one cancer from metastasizing for every 10 to 15 men treated. Prolonging adjuvant ADT also showed significant benefits, while neoadjuvant ADT was not effective beyond two months.
Researchers found that glioma cells with mutated ATRX have reduced Chk1 activity, leading to dysregulated cell cycle and heightened sensitivity to ATM inhibitors. The study suggests that combining radiation therapy with these inhibitors may improve treatment outcomes for patients with this gene mutation.
The American Society for Radiation Oncology (ASTRO) has released a new clinical guideline outlining the use of external beam radiation therapy (EBRT) to treat adult patients with primary liver cancers. The guidelines emphasize multidisciplinary care and provide evidence-based recommendations on indications, dosing, techniques, and trea...
A new post-surgery approach for treating HPV-related throat cancer uses low-dose radiation and spares the majority of patients from chemotherapy. The trial found high survival rates and quality of life in patients at medium risk for recurrence.
A recent study found that despite some progress, the US academic workforce in radiation and medical oncology remains underrepresented compared to the broader US cancer population. The study emphasizes the need for continued efforts to recruit and retain diverse faculty members.
A new diagnostic tool for breast cancer uses a low-voltage electrical current to detect changes in lymphatic interstitial fluid, showing 70% effectiveness in predicting cancer presence. The device can be used repeatedly on women of any age, providing an additional diagnostic option for younger patients and those with dense breast tissue.
Women with breast cancer are at a higher risk of developing atrial fibrillation and dying from heart-related issues within the first year. The condition was more common in women who did not receive surgery or radiation as their initial treatment.
A new study found that low-dose CT scans are as accurate as standard-dose scans in diagnosing appendicitis and differentiating between uncomplicated and complicated cases. This breakthrough could lead to reduced radiation exposure for young patients, improving treatment outcomes.
A multi-center study demonstrated improved overall survival and quality of life for inoperable pancreatic cancer patients treated with MRIdian SMART, with a median survival of 26 months. The treatment showed low rates of major adverse events and was more effective than standard radiation therapy.
A new study finds that high-dose radiation therapy can lengthen progression-free survival for people with advanced lung cancer when systemic therapy has not fully halted tumor growth or spread. Stereotactic body radiation therapy (SBRT) shows promise in treating oligoprogressive, metastatic lung and breast cancer.