Articles tagged with Neuroimaging
A global consortium has created the first map of bipolar disorder's impact on the brain, revealing clear differences in brain regions controlling inhibition and emotion. The study found significant thinning of gray matter in patients with bipolar disorder, particularly in areas responsible for emotional regulation.
A team of neuroscientists has developed a technique that predicts brain age based on MRI scans, finding a link between the discrepancy and increased risk of mental and physical health decline. The study shows that those with 'older brains' are more likely to die before 80, suggesting potential for early intervention.
Using neuroimaging techniques and multivariate statistical models, researchers found that people with older-than-chronological-age brains are more likely to experience deteriorating conditions and early death. Combining brain-predicted age with DNA-related epigenetic biomarkers improves mortality predictions.
A study published in Psychiatry Research Neuroimaging found that the reward system in women's brains is larger than in nonalcoholic women and smaller in alcoholic women than in nonalcoholic men. The study also showed a negative association between sobriety time and ventricle size, suggesting recovery from alcoholism.
A research team developed a polygenic hazard score to estimate an individual's Alzheimer disease risk based on their genetic data and age. The score predicted those with the highest risk were several times more likely to develop AD, with earlier expected onset by up to 10 years.
Brain imaging can determine whether someone is acting knowingly or recklessly during criminal activity, according to a new study. The discovery has implications for the emerging field of neurolaw and could inform punishment decisions.
A study using AI technique TDA identified patients with normal brain scans who may deteriorate months after diagnosis and develop symptoms like post-traumatic stress disorder. The research also found molecular biomarkers predictive of poor recovery, paving the way for personalized treatments.
A new potassium-sensitive fluorescence-imaging method enables accurate measurement and spatiotemporal mapping of the brain, shedding light on chemical activity within it. The nanosensor has improved spatial resolution, allowing for investigation into potassium micro-domains around activated neurons.
NeuroVision is participating in a landmark A4 study to test a new investigational treatment that may reduce beta-amyloid accumulation in the brain. The substudy will use NeuroVision's retinal imaging technology to characterize amyloid imaging findings and assess longitudinal changes.
Researchers used imaging techniques to map the brain wiring of two thylacine specimens, comparing them to the brains of living Tasmanian devils. The results suggest that the larger-brained thylacine had more cortex devoted to planning and decision-making.
Researchers from Osaka University investigated how neuronal activity influences CREB dynamics and its interactions with the cAMP response element (CRE). They found that neuronal activity increases CREB-CRE interactions, leading to increased binding of CREB to specific genomic sites.
Optical probes have been developed to overcome light scattering in deep-brain imaging, allowing for precise stimulation of neural circuits. This breakthrough enables researchers to control individual neurons with remarkable resolution, opening up new avenues for neuroscience and neuromedical research.
Studies found that early life stress associated with poverty and lack of familial support may lead to lower response to rewards, increased vulnerability to depression in children, and altered brain development. Positive maternal support appeared protective against these adverse effects on brain development.
Researchers develop space-division multiplexing optical coherence tomography (SDM-OCT) to image single neurons in live tissue, enabling label-free and depth-resolved images of neural activity. This breakthrough technology could revolutionize brain mapping and provide insights into brain disorders such as Alzheimer's and schizophrenia.
Research found promising initial evidence that specific neuroimaging markers can help predict the response to psychotherapy in patients with depression or anxiety. Neuroimaging markers such as activity in the amygdala, anterior insula, and anterior cingulate cortex may indicate which patients are more likely to benefit from psychotherapy.
A new study has found measurable brain changes in children after a single season of playing youth football, even without a concussion diagnosis. The research team analyzed head impact data and multimodal neuroimaging to determine the risk-weighted cumulative exposure associated with a single season of play.
A comprehensive rat brain atlas has been created to guide stereotaxic surgery procedures, combining high-resolution MRI images with histological sections. The atlas features a standardized reference grid and precise coordinates, enabling accurate targeting of surgical targets.
Researchers identified three distinct brain atrophy patterns associated with cognitive decline in Alzheimer's disease and mild cognitive impairment. The study found that these patterns, including cortical, temporal, and subcortical atrophy, can predict cognitive deficits and may allow for earlier diagnosis and treatment.
A massive MRI study identified seven genetic hotspots regulating brain growth, memory, and reasoning, as well as predicting the onset of Parkinson's disease. The research supports the notion that brain size can be used to measure 'brain reserve' and promote resilience to age-related brain diseases.
A recent study published by the European Society of Cardiology found that direct catheter-based thrombectomy is as effective as traditional thrombolytic treatment in treating acute ischemic strokes. The procedure was performed in a timely manner and resulted in comparable outcomes, with 41% of patients achieving good functional recover...
Researchers have optimized optogenetic methods to study neural circuits with single neuron resolution. By confining light stimulation to a defined disc-like shape and using spatially restricted ChR expression, they can unmask synaptic connections from neurons whose cell bodies lie close to the dendrites of the postsynaptic cell. This r...
Researchers at the University of Chicago found that trading experience reduces emotional pain associated with selling, leading to a decrease in the endowment effect. Brain scans showed reduced activity in areas linked to negative emotions and anticipation of losses.
A new technique called magnified analysis of proteome (MAP) allows scientists to image brain tissue at multiple scales, preserving proteins within cells and connectivity between neurons. The method enables high-resolution imaging with a resolution as high as 60 nanometers, tracing connections in the human brain more accurately.
Near-infrared spectroscopy technologies offer improved quality of life through portable, sensitive, and non-invasive diagnosis and treatment of diseases. The latest advances enable researchers to investigate complex illnesses and dysfunctions.
Athletes may experience long-term brain changes even after recovery from a concussion, according to new research. The study found alterations in brain white matter six months post-injury, with more severe symptoms at the time of the concussion being a predictor of these changes.
Scientists track brain-cell activity in mice to gain insight into how the brain creates a map to a destination. The study found that two sublayers of cells in the hippocampus process different types of learning, with one layer creating a stable internal map and the other layer updating it during navigation.
Researchers from UNC-Chapel Hill and NC State University developed a new technology to improve imaging of neuronal activity in the brain, capturing images up to 9.5 square millimeters - a 10 times larger area than previously possible.
A new imaging technique helps identify patients at risk of severe bleeding after stroke treatment by analyzing the extent of blood-brain barrier disruption. This association can inform treating physicians on the risk of bleeding and potentially guide clinical decisions.
Research from RIKEN Brain Science Institute in Japan identifies the brain clock that keeps memories organized across time. Without CA3 input, the neural orchestra loses its conductor, leading to errors in representing space and impairing accurate prediction of spatial location.
The study, published in the American Society of Neuroradiology's annual meeting, found that younger patients, African-Americans, and those seen by a stroke team received more advanced imaging, including MRI and MR angiogram. The findings highlight disparities in neuroimaging use for different patient groups.
Recent advancements in neuroimaging technology have led to better understanding and treatment of neurodegenerative diseases such as Alzheimer's. These innovations enable clinicians to detect preclinical stages of AD through PET imaging, and also provide new therapeutic interventions.
Researchers propose Spherical Brain Mapping (SBM) to detect Alzheimer's disease, achieving 91% accuracy in differential diagnosis. The framework projects three-dimensional MR brain images onto two-dimensional maps, revealing statistical characteristics of tissue, and can be visually assessed for diagnosis.
The Open Neuroimaging Laboratory aims to aggregate annotated brain imaging data and develop a tool for distributed team collaboration. The project seeks to improve transparency, statistical power, and reproducibility in brain data analysis.
Recent research reveals that visual brain maps are dark-centric, with greater precision for darker stimuli. This dark-centric organization enables the brain to represent different positions of light spots as rotating around a dark anchor in visual space.
Researchers found that difficulties building cognitive maps of new surroundings could indicate Alzheimer's disease. Participants with preclinical Alzheimer's disease showed significant challenges forming cognitive maps but not route learning tasks, highlighting the hippocampus and caudate as early affected brain regions.
This year's top winners include a study on benign disorders simulating thoracic malignancies and a thorough understanding of ankle nerves for nerve entrapment evaluation. B-flow imaging is also highlighted as a promising method to complement color Doppler ultrasound.
Researchers found lower metabolism and reduced brain size among study participants taking anticholinergic drugs, which may increase risk of cognitive impairment and dementia. The study provides insight into the potential underlying biology of these clinical links using neuroimaging measurements.
A recent study by the American Academy of Neurology found that over 40% of retired NFL players showed signs of traumatic brain injury based on sensitive MRI scans. The study also revealed a significant correlation between longer NFL careers and increased risk of TBI.
Researchers found that brain swelling in mice with experimental cerebral malaria starts in the olfactory bulb and spreads along a specific path called the rostral migratory stream. This path is used by immature nerve cells and immune cells, allowing the progression of inflammation into the central nervous system.
Researchers found that brain imaging can accurately predict patient outcomes and identify those who may benefit from clot removal up to 18 hours after symptom onset. This approach could improve treatment eligibility and outcomes for ischemic stroke patients.
International neurointerventional societies have released new training guidelines to improve the treatment of ischemic stroke patients. The guidelines aim to ensure that physicians performing inside-the-artery clot removal in the brain have the necessary education and training, leading to better patient outcomes.
Children with sensory processing disorder (SPD) have altered brain connectivity pathways compared to typically developing children, affecting auditory and tactile processing. The study found strong correlations between white matter integrity and sensory functioning, paving the way for personalized treatments.
A woman with treatment-resistant depression was found to have a brain tumor after symptoms persisted for six months despite antidepressant and anti-anxiety medication. The tumor, located in her left frontal lobe, was later treated successfully with emergency surgery, resulting in the disappearance of depressive symptoms.
Researchers at the Salk Institute used genetic techniques to visualize three brain cell types in the visual cortex, shedding light on how the brain processes visual information. The study provides new insights into neural circuits and their potential implications for neurological disorders like schizophrenia and autism.
A new study using MRI scans found that 52% of active duty military personnel with blast-related mild traumatic brain injury (MTBI) have white matter T2 hyperintensities, also known as 'brain scars'. Pituitary abnormalities were identified in almost a third of MTBI patients.
Researchers at The Neuro compiled a detailed map of the hippocampus, improving tools for diagnosing and treating epilepsy. The new atlas provides non-invasive ways to assess therapy impact and improve patient quality of life.
A new study maps specific schizophrenia symptoms to distinct brain circuits, revealing novel connections between cognitive, emotional, and intellectual symptoms. The findings have important implications for diagnosis and treatment, suggesting that brain scans could help identify individual patients and track progress during therapy.
Scientists can now observe neurons' electrical activity in real-time using a highly sensitive molecule fused with a fluorescent protein. This breakthrough allows researchers to study brain processing in living animals, offering unprecedented insights into cell-to-cell communication.
Researchers at the US Naval Research Laboratory have developed luminescent nanoparticles to image brain function, enabling real-time mapping of neural connections. The nanoparticles, specifically quantum dots, can track action potential changes with high fidelity and are ideal for interfacing with neurons.
Researchers at City College of New York have introduced a new optical window, dubbed the Golden Window, which enables deeper brain tissue imaging. This breakthrough has significant implications for the noninvasive study of the brain and breasts, reducing scattering that causes blurring in previous methods.
Researchers mapped the human brain's experience of gratitude using Holocaust survivors' testimonies, revealing areas responsible for feelings of reward and moral cognition. The study also showed that gratitude enhances empathy and understanding of historical events.
Researchers at Penn developed a new neuroimaging method that uses glutamate detection to identify epileptic lesions in patients with medication-resistant epilepsy. The GluCEST imaging method was tested on four patients and confirmed the location of the seizures with high accuracy.
Researchers have developed a new noninvasive light-based imaging technology that can see inside the living brain, providing a tool to study how diseases change brain tissue over time. The method doubles the image depth range, enabling examination of acute and chronic morphological or functional vascular changes in the deep brain.
Researchers matched behavioral symptoms to specific brain abnormalities, providing a new way of thinking about schizophrenia. The study found distinct subgroups of patients with schizophrenia that correlate with symptoms, offering a step toward improving diagnosis and treatment.
Research reveals fundamental rules governing brain regions' ability to exert control over thoughts and actions, using structural imaging techniques and network science. The frontal cortex's role in cognitive control is mechanistically explained, shedding light on its dynamic control of trillions of individual neurons.
Researchers replicate previous finding on how the brain processes music using a naturalistic free listening context, demonstrating reliable results and ecologically valid findings. The study fine-tunes previous findings, concluding which brain areas are involved in processing different musical elements.
A study using MRI to evaluate 603 military service members with TBI found that cerebral microhemorrhages were more common among those imaged within three months post-injury. Early detection of microbleeding could provide important information regarding disease progression or recovery.
Researchers emphasize the need to improve brain imaging accuracy for dementia diagnosis and progression prediction. MRI scans and PET scans show promise, but current methods are not sensitive or accurate enough for widespread adoption.
A study published in Vision Research found that amblyopia, or 'lazy eye,' alters the brain's visual pathways, making it harder for the brain to adapt to using the weaker eye. The research suggests a potential new approach for treating vision disorders, including adults.
Researchers used non-invasive brain-imaging tool to detect pathways connecting basal ganglia regions, improving understanding of circuitry. The breakthrough could lead to technologies to track disease progression for Parkinson's and other neurological disorders.