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Different brain atrophy patterns may explain variability in Alzheimer's disease symptoms

Researchers identified three distinct brain atrophy patterns associated with cognitive decline in Alzheimer's disease and mild cognitive impairment. The study found that these patterns, including cortical, temporal, and subcortical atrophy, can predict cognitive deficits and may allow for earlier diagnosis and treatment.

SourceMassachusetts General Hospital·JournalProceedings of the National Academy of Sciences·DateOct 7, 2016

Does brain size really matter?

A massive MRI study identified seven genetic hotspots regulating brain growth, memory, and reasoning, as well as predicting the onset of Parkinson's disease. The research supports the notion that brain size can be used to measure 'brain reserve' and promote resilience to age-related brain diseases.

SourceUniversity of Southern California·JournalNature Neuroscience·DateOct 5, 2016

Imaging the brain at multiple size scales

A new technique called magnified analysis of proteome (MAP) allows scientists to image brain tissue at multiple scales, preserving proteins within cells and connectivity between neurons. The method enables high-resolution imaging with a resolution as high as 60 nanometers, tracing connections in the human brain more accurately.

SourceMassachusetts Institute of Technology·JournalNature Biotechnology·DateJul 26, 2016

The brain clock that keeps memories ticking

Research from RIKEN Brain Science Institute in Japan identifies the brain clock that keeps memories organized across time. Without CA3 input, the neural orchestra loses its conductor, leading to errors in representing space and impairing accurate prediction of spatial location.

SourceRIKEN·JournalNature Neuroscience·DateMay 30, 2016

Fifteen international neurointerventional societies join to release new training guidelines to help ensure optimal outcomes for ischemic stroke patients

International neurointerventional societies have released new training guidelines to improve the treatment of ischemic stroke patients. The guidelines aim to ensure that physicians performing inside-the-artery clot removal in the brain have the necessary education and training, leading to better patient outcomes.

SourceSociety of NeuroInterventional Surgery·JournalJournal of NeuroInterventional Surgery·DateFeb 17, 2016

Brain tumor revealed by treatment-resistant depression

A woman with treatment-resistant depression was found to have a brain tumor after symptoms persisted for six months despite antidepressant and anti-anxiety medication. The tumor, located in her left frontal lobe, was later treated successfully with emergency surgery, resulting in the disappearance of depressive symptoms.

SourceBMJ Group·JournalBMJ Case Reports·DateDec 22, 2015

Neurological underpinnings of schizophrenia just as complex as the disorder itself

A new study maps specific schizophrenia symptoms to distinct brain circuits, revealing novel connections between cognitive, emotional, and intellectual symptoms. The findings have important implications for diagnosis and treatment, suggesting that brain scans could help identify individual patients and track progress during therapy.

SourceUniversity of North Carolina Health Care·JournalMolecular Neuropsychiatry·DateNov 24, 2015

Noninvasive imaging method looks deeper inside the body to study living brain

Researchers have developed a new noninvasive light-based imaging technology that can see inside the living brain, providing a tool to study how diseases change brain tissue over time. The method doubles the image depth range, enabling examination of acute and chronic morphological or functional vascular changes in the deep brain.

SourceSPIE--International Society for Optics and Photonics·JournalJournal of Biomedical Optics·DateOct 13, 2015

How the brain's wiring leads to cognitive control

Research reveals fundamental rules governing brain regions' ability to exert control over thoughts and actions, using structural imaging techniques and network science. The frontal cortex's role in cognitive control is mechanistically explained, shedding light on its dynamic control of trillions of individual neurons.

SourceUniversity of Pennsylvania·JournalNature Communications·DateOct 6, 2015

Reproducible neuroscience with real tango

Researchers replicate previous finding on how the brain processes music using a naturalistic free listening context, demonstrating reliable results and ecologically valid findings. The study fine-tunes previous findings, concluding which brain areas are involved in processing different musical elements.

SourceAcademy of Finland·JournalNeuroImage·DateSep 25, 2015

Take a trip through the brain

Researchers develop novel imaging technology to visualize brain's intricate structures, including neurons and blood vessels. The breakthrough enables scientists to study neurological disorders and understand how brain development shapes individual identity.

SourceCell Press·JournalCell·DateJul 30, 2015

Altruism is simpler than we thought

A computational model suggests that generosity and selfishness can be both fast and effortless, depending on the person and context. The model indicates that people are happier when mistaken generosity doesn't happen, highlighting the importance of focusing on others' thoughts and experiences.

SourceCell Press·JournalNeuron·DateJul 15, 2015

Redrawing language map of brain

Scientists have updated the traditional brain map of language comprehension by discovering a new location for word comprehension in the left anterior temporal lobe. Sentence comprehension is found to be distributed widely throughout the language network, contradicting previous theories. The study provides a more precise target for futu...

SourceNorthwestern University·JournalBrain·DateJun 25, 2015

Saving critical time diagnosing stroke patients with MRI by borrowing 'lean' principles

Two Washington-area hospitals used lean manufacturing principles to reduce door-to-needle times for stroke patients, from 93 to 55 minutes, by streamlining their processes and improving teamwork. The techniques, known as SMART, can be applied to other hospitals using CT scans, allowing more efficient use of MRI scans in acute stroke care.