Articles tagged with Neuroimaging
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Neuroscientists at USC will establish two Centers of Excellence to mine brain data, aiming to identify new treatments for autism, Alzheimer's disease, and mental illness. The $23 million awards total $12 million and $11 million over four years, supporting large-scale analyses that could revolutionize neurological research.
Researchers at Salk Institute will create an epigenetic map of each cell type in the brain, allowing for deeper understanding of neurons' identity and functional differences. The study aims to reveal possible windows into brain development and disease.
A new MRI technique using Diffusion Tensor Imaging (DTI) can help clinicians predict the likelihood of poor clinical outcomes following mild traumatic brain injury. This technique shows significant differences in white matter between mTBI patients with positive versus negative findings on CT and MRI evaluation.
A new study reveals that bats process complex spatial information by dynamically adapting their brain maps to external factors. By enhancing neuronal signals for objects in close proximity, bats can magnify the appearance of nearby obstacles, enabling them to navigate safely.
Chronic use of codeine-containing cough syrups is associated with brain white matter deficits, particularly in regions involved in impulse control. These changes are linked to increased impulsivity traits and correlate with the duration of CCS use.
Researchers used ultrasound to monitor chitosan nerve conduits in rats, revealing unsatisfactory complications and degradation modes. This non-invasive technique enhances the assessment of nerve conduit outcomes, advancing peripheral nerve tissue engineering.
Researchers developed a new model explaining how autism occurs, with genetically-controlled brain plasticity mechanisms potentially determining autistic capabilities and subtypes. The 'Trigger-Threshold-Target' model suggests focusing on developing children's unique strengths rather than solely correcting behaviors.
The new journal Neurophotonics adds to the rapidly growing understanding of the brain through advanced optical methods and applications. Key findings include photoacoustic tomography techniques that display brain activity with high accuracy, and novel technologies for brain energy metabolism.
Cerebral microbleeds have been shown to be a significant marker for diffuse axonal injury, which can lead to severe neurological disorders. The study highlights the importance of using susceptibility-weighted imaging to detect these tiny changes and evaluate traumatic cerebral microbleeds with high sensitivity.
A 3D image of a Paleolithic child's skull shows compound fractures indicating blunt force trauma, likely caused by interpersonal violence. The child is believed to have suffered from severe traumatic brain injury, which may have impacted their social communication and behavior.
A new noninvasive optical imaging device has been shown to detect changes in the retina that occur before clinical diagnosis of Alzheimer's disease. The device, developed at Cedars-Sinai, can differentiate between Alzheimer's and non-Alzheimer's diseases with high sensitivity and specificity.
A novel biomarker predicts which individuals will develop epilepsy after febrile seizures, according to a UC Irvine study. The diagnostic ability could lead to improved use of preventive therapies for the disorder.
Researchers at Cedars-Sinai have created 3-D computer models to map the brain region involved in dystonia, identifying an anatomical target for further study. The models provide information for neurologists and neurosurgeons to consider when planning surgery and making device programming decisions.
A new study reveals that childhood maltreatment is associated with cerebral grey matter abnormalities, leading to lasting changes in brain structure. The research found significant deficits in late-developing brain regions, indicating a potential link between adverse childhood experiences and long-term cognitive and emotional deficits.
A new review highlights the need for healthcare professionals to be aware of rare causes of headaches in pregnancy, including conditions like idiopathic intracranial hypertension and cerebral venous thrombosis. These conditions can be fatal if not treated promptly and require prompt medical attention.
Researchers discovered that octopuses' suckers temporarily lose grip on their own skin due to a chemical produced by the skin, preventing them from getting tangled. This mechanism allows for flexible manipulation and may inspire bioinspired robot design.
A new study found that access to electronic health records (EHRs) can significantly impact the interpretation of head CT scans, potentially leading to adverse effects on medical management. In nine percent of cases, EHR data was deemed crucial for accurate diagnosis, highlighting the importance of widespread EHR adoption.
A new high-throughput imaging method called CUBIC enables rapid whole-brain imaging at single-cell resolution, overcoming previous limitations. This allows for unprecedented insights into gene expression patterns and neural networks in the brain.
A study found that neuroimaging for headaches is frequently ordered by physicians, with a significant increase in use from 1995 to 2010. The procedure resulted in estimated costs of $3.9 billion and was performed in nearly 14% of all headache visits.
A new study found that 12% of doctor visits for headaches result in unnecessary brain scans, costing around $1 billion annually. The researchers suggest better public education and insurance plan designs could reduce unnecessary use and spending on scans.
Researchers found that brain pathways adaptively change between detecting and discriminating sensory inputs, such as headlights in the distance. The study used animal models and optical imaging to directly assess how acuity is controlled in the brain.
A study found that people with both parents having Alzheimer's disease showed more severe brain abnormalities, including increased brain plaques and reduced brain volume. The research suggests a possible genetic link to the development of Alzheimer's disease.
Researchers developed a reliable 3-D MRI imaging technique to study premature brain development. This allows for early identification of delayed tracts and potential treatments, enabling proactive therapies within weeks of birth.
Researchers found individuals are more satisfied with truth-telling rewards than deceitful ones. The studies explored two types of deception and discovered a liar's brain responds differently when gaining rewards through truth or lies.
Researchers at IU School of Medicine will use advanced neuroimaging techniques to study high school athletes and understand the impact of concussions on brain blood flow. The study aims to improve understanding of concussion symptoms, cognitive functioning, and detection methods.
Researchers at the University of Pennsylvania have developed a brain development index from MRI scans that captures normal brain maturation patterns. The study shows a relationship between cognitive development and physical changes in the developing young brain, allowing for early detection of subtle developmental abnormalities.
The NIH has selected eight projects to study the long-term effects of repeated head injuries and develop more accurate concussion diagnoses. The partnership between the NIH and the NFL aims to reduce the risk of chronic traumatic encephalopathy (CTE) in athletes and military personnel.
A new study from CAMH found that people carrying the SORL1 gene for Alzheimer's disease show brain changes beginning in childhood. These changes are linked to an increased risk of late-onset Alzheimer's, a condition that typically appears decades later.
A study by Aron Barbey and colleagues identified a network of brain areas in the frontal and parietal cortex essential for discourse comprehension. The researchers used voxel-based lesion-symptom mapping to create a collective map of the cerebral cortex, revealing that executive control is critical for integrating language with prior k...
Studies show that concussions can lead to brain abnormalities four months after symptoms have resolved, with memory and behavioral issues improving more quickly than physical injuries. These findings suggest that healing from concussions may be similar to recovering from burns, with tissue scabs forming before the body is fully healed.
The hospital achieved excellence through strategies such as reducing overhead paging and establishing daily hospital huddles to prioritize patient needs. UT Southwestern's neurology and neurosurgery programs are nationally ranked.
The new journal will cover a range of topics including microscopic methods, optogenetics, and computational methods relevant to understanding brain function. It aims to foster greater awareness and interaction among the photonics, neuroscience, and clinical communities.
Researchers analyzed 36 cases of inflammatory demyelinating pseudotumor in the spinal cord, finding that patchy reinforcement on MRI and inflammatory cell infiltration are key features. The study aims to reduce misdiagnosis rate and improve patient quality of life by providing accurate imaging and clinical properties.
Researchers found increased iron deposits in deep gray matter of patients with clinically isolated syndrome (CIS), a precursor to Multiple Sclerosis (MS). The study also revealed subtle brain damage and lack of correlation between iron deposits and jugular vein diameter, casting doubt on the Zamboni hypothesis.
A study of 70 elderly adults found that shorter sleep duration and poorer sleep quality were associated with greater beta-amyloid buildup in the brain, a hallmark of Alzheimer's disease. The research suggests that optimizing sleep may help prevent or slow AD progression.
A new Pain and Interoception Imaging Network (PAIN) will feature hundreds of brain scans and clinical information to tease out similarities and differences between chronic-pain conditions. The database aims to improve research and treatment development for conditions like migraine, irritable bowel syndrome, and rheumatoid arthritis.
A team of researchers led by LA BioMed's Patricia Dickson will use state-of-the-art brain imaging to study the brains of disease models with mucopolysaccharidosis (MPS), a genetic disease causing cognitive deterioration, memory loss and dementia. The goal is to gain greater understanding of MPS brain disease and develop new treatments.
Researchers have created a new map of bird brains based on a decade-long exploration of gene expression across eight species. The findings suggest that bird brains have commonalities with human brains, including columnar organization and forebrain regions similar to mammals.
Scientists have developed a high-speed imaging technique with single-neuron resolution that can record the activity of 70% of nerve cells in a worm's head. This breakthrough allows for detailed maps of how neurons are wired up in the brain and information on how networks interact in real time.
Researchers at MIT and Boston Children's Hospital found a correlation between poor pre-reading skills in kindergartners and the size of a brain structure that connects language-processing areas. This study aims to identify children with dyslexia earlier, allowing for early intervention.
A team of scientists has mapped the complex neural connectivity in a fly's brain essential for vision, revealing new insights into how flies detect motion. The researchers used a high-throughput approach to chart neuronal connections involved in motion detection, identifying 379 cells and 8,637 connections between them.
Researchers at the Salk Institute found that altering cortical layout can produce significant changes in connected brain regions, potentially underlying neural developmental problems. This discovery provides insights into the development of autism and other neural disorders.
A team of researchers from Imperial College London has developed a map of a typical bird brain, showing how different regions are connected to process information. They discovered that areas important for high-level cognition, such as long-term memory and problem-solving, have similar wiring patterns to those in human brains.
A recent study published in the American Journal of Neuroradiology found that women with mild cognitive impairment experience higher rates of cognitive decline than men, while all women exhibit greater regional brain loss over time. The study's authors suggest that hormonal differences may play a role in these findings.
The BigBrain atlas provides nearly cellular resolution, allowing researchers to see details close to the level of individual cells. This high-resolution model can be used for various applications such as computational modeling, simulating brain functions and analyzing data from MRIs and PET scans.
The BigBrain project presents a landmark three-dimensional digital reconstruction of the human brain with a spatial resolution of 20 microns. This allows for unprecedented exploration of brain microstructure and cellular level details, facilitating new insights into neurobiology, cognition, and aging.
A pioneering study demonstrates the benefit of MRI in identifying mental illnesses such as bipolar disorder. The advanced imaging technique was able to correctly distinguish patients from healthy individuals with a high degree of accuracy, promising a new approach to diagnosis.
A recent study published in Social Cognitive and Affective Neuroscience found that meditation can significantly reduce normal everyday anxiety in healthy individuals. The study used arterial spin labeling magnetic resonance imaging to examine brain activity before and after four 20-minute mindfulness meditation sessions.
Researchers used virtual reality to study how brain cells create maps of the world, revealing that environmental cues such as smell and sound play a major role in activating these cells. The findings provide new insights into how the brain learns and makes memories.
Researchers at UCLA found that individuals with body dysmorphic disorder (BDD) have abnormal brain connections, which may impair information processing. The study suggests that these patterns in the brain relate to impaired symptoms, particularly compulsive behaviors.
Researchers at Johns Hopkins have developed a minimally invasive procedure that uses a stent to alleviate symptoms of pseudotumor cerebri by expanding narrowed veins and relieving fluid pressure. The study shows promising results, with 10 out of 12 patients experiencing complete and lasting recovery.
A UCLA-led study found that clot-removal devices do not improve recovery from clot-caused strokes. However, a new generation of devices shows better results and may offer improved outcomes.
A study found that brain imaging after mild traumatic brain injury (mTBI) or concussion can detect microbleed lesions and tube-shaped linear lesions, which may be associated with vascular injury. These lesions could potentially provide a target for treating people with mTBI.
Heavy drinkers show greater and faster acetate uptake and metabolism in the brain compared to light drinkers. Acetate can serve as an alternative energy source, potentially alleviating withdrawal symptoms during detoxification.
Researchers at Virginia Tech Carilion Research Institute found that cold reasoning and hot feelings are intimately connected in the brain. The study used a fairness probe called the ultimatum game, which showed that feelings about offers tracked well-defined computations, indicating no clean separation between rational decision-making ...
Researchers found that brain regions responsible for making decisions continue to be active even when the conscious brain is distracted, leading to better decision-making. The study suggests that our brains unconsciously process decision information in ways that improve effective problem-solving and decision-making.
Researchers found that excess alpha-synuclein protein disrupts vital recycling processes in neurons, leading to progressive degeneration and cell death. The study provides a structural and mechanistic explanation for the progression of Parkinson's disease, shedding light on its causes and mechanisms.
Researchers at University of Toronto Scarborough identified overactive negative emotion processing and underactive emotional regulation in people with Borderline Personality Disorder (BPD). This study provides valuable evidence for improving BPD diagnosis and treatment through brain imaging.
A new study reveals that fetal alcohol exposure alters brain structure and metabolism in children, with MRI techniques showing statistically significant thinning of the corpus callosum. Diffusion weighted imaging also detected increased diffusion, indicative of neurological disorders or brain damage.
A new study found that newborn rats' whisker twitches are linked to bursts of brain activity, suggesting a crucial role in developing sensorimotor systems. The discovery sheds light on the importance of involuntary movements during sleep in infant brain development.