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Stem Cells journal awards human cord-blood research

A recent study published in Stem Cells journal has awarded human cord-blood research with a $10,000 prize for its potential to cure acute kidney injury. The research revealed the regenerative potentials of human cord-blood stem cells as a future cell therapy.

McMaster scientists turn skin into blood

Scientists at McMaster University have discovered how to make human blood directly from adult skin cells, bypassing the need for a pluripotent stem cell conversion. This breakthrough could lead to new treatments for patients in need of blood transfusions, reducing reliance on donor matches and increasing access to life-saving therapies.

Scripps Research team implicates wayward DNA-repair enzyme in Friedreich's ataxia

The Scripps Research Institute scientists have found strong evidence that a DNA repair enzyme is involved in the expansion of triplet repeats in the FXN gene, leading to the silencing of the gene and the disease. The study suggests that the enzyme mistakenly identifies the repeat expansions as DNA damage and attempts to repair them.

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MRI contrast agents change stem cell proliferation

Researchers tested three MRI contrast agents on different stem cell populations and found changes in stem cell proliferation depending on the agent used. The study revealed varying labeling efficiencies with each agent, but no significant alterations in cell phenotypes or differentiation.

DJI Air 3 (RC-N2)

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Plant stem cells could be fruitful source of low-cost cancer drug

A study suggests that plant stem cells derived from trees could be used to produce the anticancer compound paclitaxel at a low cost. This method avoids the use of mature trees and environmentally damaging by-products associated with current industrial manufacturing processes.

Davis Instruments Vantage Pro2 Weather Station

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Singapore scientists first to perform genome-wide study of human stem cells

A team of Singaporean scientists has made a major breakthrough by discovering the most important genes in human embryonic stem cells, which are crucial for treating debilitating conditions. The researchers identified a particular gene called PRDM14 that makes it easier to turn adult cells into pluripotent stem cells.

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Stem cells repair damaged spinal cord tissue

Researchers at Karolinska Institutet have discovered how stem cells and other cells repair damaged spinal cord tissue in mice. The study identified ependymal cells as a key player in this process, which is crucial for developing therapies for spinal cord injury.

Stem cells shape up to their surroundings

Research in the Journal of Tissue Engineering reveals that stem cells detect surface features with mechanosensors, which modulate gene expression through biochemical signaling cascades. This understanding opens doors to develop improved clinical prostheses with topographies that directly modulate stem cell fate.

Celestron NexStar 8SE Computerized Telescope

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Elasticity found to stretch stem cell growth to higher levels

A team of researchers has found a way to increase the number of blood-forming stem cells by using a unique stretchy surface. This breakthrough could revolutionize stem cell transplants by generating up to three times more stem cells than current methods.

Technique to reattach teeth using stem cells developed at UIC

Researchers at UIC's Brodie Laboratory have successfully developed a technique to reattach teeth using stem cells, which could lead to a major advance in the battle against gum disease. The new strategy involves using periodontal ligament stem cells to form new fibrous attachments between the tooth and bone.

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'Firefly' stem cells may help repair damaged hearts

Engineered 'firefly' stem cells can help repair damaged hearts without cutting into patients' chests. Researchers can now track the cells' progress using a special camera lens that picks up the glow under a microscope.

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OHSU research team joins elite consortium dedicated to curing type 1 diabetes

A multi-center team of scientists from OHSU is part of the prestigious Beta Cell Biology Consortium, aiming to develop a cell-based therapy for insulin delivery in type 1 diabetes patients. The researchers hope to produce abundant quantities of functional human insulin-producing beta cells that can be used for transplantation.

Keeping stem cells from changing fates

A study published in Cell Stem Cell reveals that NURF, an enzyme that regulates DNA packaging, allows specific genes to be turned on and off in stem cells. This dynamic structure enables stem cells to maintain their potency and prevent differentiation into other cell types.

Physical environment influences stem cell development

Researchers at Hebrew University develop theoretical model and conduct experiments to understand how stem cells differentiate based on their surroundings' rigidity. The study reveals elongated, muscle-like fibers in cells on rigid supports, differing from brain and bone cell structures on softer or harder substrates.

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MIT researchers develop a better way to grow stem cells

Scientists at MIT have developed a new synthetic surface that allows human pluripotent stem cells to stay alive and continue reproducing themselves for at least three months. This breakthrough enables the growth of large quantities of cells, necessary for treating diseases such as Parkinson's disease and spinal cord injuries.

Stem cell versatility could help tissue regeneration

Scientists have successfully converted stem cells from a key immune system organ into skin stem cells without genetic modification. This breakthrough allows for potential applications in regenerating tissues and has implications for the development of new therapies.

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Are there too many stem cell journals?

The University of South Florida researchers warn that the growing number of stem cell journals may compromise the quality of research in the field. They recommend authors to follow Good Publications Practices when choosing a publication outlet.

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Human embryonic stem cells purified in new, rapid technique

Researchers at UCSF have successfully purified one type of human embryonic stem cell using a novel, high-throughput strategy that avoids genetic engineering. The technique links two existing technologies and enables the separation of pure stem cells from teratoma-forming cells at a rate of about 25,000 cells per second.

New insights into how stem cells determine what tissue to become

Stem cell differentiation is a crucial process that can be accelerated using a novel type of matrix, adjusting its stiffness without altering its chemical composition. By analyzing traction forces and cellular behavior, researchers predict stem cell differentiation as early as Day 1.

6 researchers to receive prestigious awards from the American Society of Hematology

The American Society of Hematology will honor six scientists with significant contributions to the understanding and treatment of hematologic diseases. Volker Diehl, Sanford Shattil, David T. Scadden, Leonard I. Zon, Barry S. Coller, and Joel S. Bennett will receive awards for their pioneering research in Hodgkin lymphoma, platelet cel...

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Researchers pinpoint key stem cells for eating and sex

Dr. Anthony-Samuel LaMantia's research identifies stem cells responsible for generating nerve cells involved in eating, reproduction, and social behavior. These cells are essential for understanding neurological and mental disabilities, such as autism, schizophrenia, and Alzheimer's disease.

Stanford scientists develop new way to grow adult stem cells in culture

Researchers at Stanford University School of Medicine developed a technique to grow muscle stem cells on a synthetic matrix that mimics the elasticity of real muscle, allowing them to maintain their self-renewing properties. This breakthrough may revolutionize the production of adult stem cells for therapies.

Skin cells could help discover cause of Parkinson's disease

Researchers are using induced pluripotent stem cells from skin tissue to grow dopamine neurons and study Parkinson's disease. The goal is to better understand the cause of the disease by comparing healthy cells with those affected by Parkinson's.

Apple Watch Series 11 (GPS, 46mm)

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Neural stem cells attack glioblastoma cells

Researchers identify a protein released by neural stem cells that induces signaling in glioblastoma cells, causing them to differentiate. This discovery could lead to new therapy concepts targeting tumor stem cells and potentially destroying the aggressive brain tumors.

Researchers identify factors behind blood-making stem cells

Researchers at the University of Montreal have identified three proteins that regulate blood cell production and one protein that inhibits it. Understanding these factors is crucial for developing novel therapies to treat diseases caused by abnormal blood-making stem cells.

GQ GMC-500Plus Geiger Counter

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Work-life balance: Brain stem cells need their rest, too

Researchers have identified a key molecular guard that prevents brain stem cells from proliferating, protecting the brain against excessive cell division. This study highlights the importance of bone morphogenetic factor protein (BMP) signaling for maintaining neural stem cells throughout adulthood.

Texas A&M researcher explains how embryo fights retroviral infection

A Texas A&M researcher has found that early mammalian embryos possess three stem cell lineages with different viral silencing strategies, including XEN cells that exhibit rapid and aggressive silencing of retroviruses. The study provides new insights into fetal diseases and has profound implications for diagnosis and treatment.

AmScope B120C-5M Compound Microscope

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Florida State researcher uncovers protein's role in cell division

A Florida State University researcher has identified the important role that CDK5RAP2 plays in maintaining centriole engagement and cohesion, thereby restricting centriole replication. This discovery could lead to a greater understanding of stem cells and their connection to human diseases such as small brain syndrome.