Research on death rates and what drives them. Covers cancer-linked stroke, COVID underreporting, hemoglobin levels, and education and survival.
The study highlights the increasing global burden of childhood diabetes, with rising deaths and disability-adjusted life-years. Improved understanding of diabetes epidemiology in children is crucial for prevention and control efforts.
A study of US state-level maternal mortality from 1999 to 2019 found increased risk among American Indian, Alaska Native, and Black individuals. The study highlights persistent disparities in maternal health care, with limited impact on prevention efforts.
A new study found that maternal mortality rates have worsened from 1999 to 2019, with the highest rates seen in Black women. The study used data from 1999 to 2019 and found significant disparities in maternal mortality rates across states and racial/ethnic groups.
Death rates due to unintentional poisonings and firearm homicides rose substantially in the US from 1999 to 2020, highlighting a pressing public health concern. The study's findings underscore the urgent need for targeted interventions to address this alarming trend.
A deep learning-based model developed in 7,105 patients predicted 30-day all-cause mortality in patients with CAP with AUCs ranging from 0.77 to 0.80. The model showed higher specificity than the CURB-65 score at the same sensitivity.
A large Swedish study found that higher cardiorespiratory fitness may lower the incidence and mortality rates of certain cancers in men. The researchers suggest prioritizing CRF interventions for individuals with low fitness levels.
A study published in Neurosurgery found that surgical stabilization of odontoid fractures is associated with better outcomes, including lower rates of nonunion, myelopathy, and mortality. The study used propensity score analysis to compare surgical stabilization with nonoperative treatment and found significant benefits in both surviva...
A study found disparities in Hispanic cancer mortality rates, with higher rates for men in certain age groups and women for liver, pancreatic, and uterine cancers. The researchers highlight the need for targeted education and screening efforts to address these disparities.
A large clinical trial found that monthly vitamin D supplements reduced the risk of major cardiovascular events such as heart attacks by 9% in older adults. The study involved over 21,000 Australians aged 60-84 and showed a significant reduction in heart attack rates, but no difference in stroke rates.
A study by Penn State researchers found that minority communities bore the brunt of the opioid crisis, with Black men and American Indian/Native Alaskan men and women disproportionately affected. The researchers suggest that race- and gender-specific interventions may be more effective in preventing overdose deaths.
A randomized controlled trial found that time-restricted eating produced similar weight loss results to traditional calorie counting in a racially diverse population of adults with obesity. Participants who engaged in 8-hour time-restricted eating had improved insulin sensitivity compared to those in the control group.
A new study finds that exposure to posthospitalization home-delivered meals is associated with lower 30-day rehospitalization and mortality rates. The study suggests that this service may help prevent hospital readmissions and improve patient outcomes.
A new study reveals increased excess mortality rates in US rural counties during the second year of the COVID-19 pandemic. Excess mortality rates decreased in large metropolitan areas but remained high in rural areas, despite vaccine availability.
A new study estimates a total of 1,179,024 excess deaths from March 2020 to February 2022, with significant increases in rural counties. The findings highlight the sustained burden of mortality in rural areas despite vaccine development and policy changes.
US delivery-related hospital mortality decreased for all groups between 2008 and 2021, while severe maternal morbidity increased, particularly among older women and minority patients with comorbidities
Head and neck squamous cell carcinoma patients face substantial burden of uncontrolled cardiovascular risk factors, leading to increased risk of stroke and heart attack. Modifiable CV risk factor control is crucial in reducing the risk of adverse cardiovascular events and death among these patients.
A recent study found that elderly patients treated in local intermediate care units have lower mortality rates and fewer hospital readmissions. The research suggests that Norway's healthcare system has improved with the introduction of these units, providing better integrated services adapted to individual users.
The study found a decreasing trend in the global TBL cancer burden from 1990 to 2019, but regional variations persisted. The burden was highest in upper-middle-income countries and lowest in high-income countries.
The study found that while there has been a decline in child mortality rates in Ethiopia, too many children are still dying. The country's neonatal mortality rate is significantly higher than the global target of 12 deaths per 1000 livebirths by 2030.
A new study revealed significant racial and ethnic disparities in US alcohol-related deaths during the Covid-19 pandemic. American Indian and Alaska Native populations saw a more than doubling of alcohol-related deaths, while Black Americans, Hispanic Americans, and Asian Americans experienced substantial increases as well.
The USPSTF recommends regular screening for depression in the adult population to address its significant impact on daily functioning. Major depressive disorder can lead to increased mortality if left untreated.
Researchers found female babies with CDH have a 32% higher risk of dying within 30 to 60 days of birth compared to males. The study, using medical records from an international registry, suggests that lower birth weights for females may be linked to the disparity in survival rates.
A recent study published in JAMA found that continuous meropenem administration did not improve mortality rates or reduce the emergence of drug-resistant bacteria in critically ill patients with sepsis. The results suggest that intermittent administration may be a more effective treatment strategy for this condition.
A new study reveals sickle cell disease is far deadlier than its textbook description, with a total mortality burden of 373,000 deaths in 2021. The condition disproportionately affects children, adolescents, and young adults worldwide, highlighting the need for universal newborn screening and early intervention.
A study of 142 nations found a strong link between access to formal financial services and lower COVID-19 mortality rates. Access to bank accounts, credit cards, or loans from a financial institution is a key predictor of lower mortality risk, even stronger than comorbidities.
A new study analyzing death records data found that men had a 2–3 times greater rate of overdose mortality from opioids and psychostimulants. The researchers noted that biological, behavioral, and social factors likely combined to increase the mortality risk for men.
Researchers at Tulane University have identified a synthetic compound called dimethyl malonate that can prevent coagulopathy during massive hemorrhages. The study found that this compound inhibits excessive cellular metabolism, preventing the glycocalyx from shedding and causing bleeding to stop.
A machine-learning study has found that individual characteristics, including age and weight, determine which drug combinations most effectively reduce COVID-19 recurrence rates. The study used real-world data from a hospital in China and identified unique treatment combinations for different demographic groups.
A study published in The BMJ found that women diagnosed with early stage breast cancer today can expect to become long term cancer survivors. The average risk of dying from breast cancer in the five years after a diagnosis has fallen from 14% to 5% since the 1990s.
Research suggests that the Bhopal gas disaster had long-term intergenerational effects on health and education. Men exposed in utero to toxic gas had a higher risk of disabilities and cancers, while those born later had reduced educational attainment. The sex ratio of births also changed among children born near the incident site.
A Dartmouth-led project has updated the Know Your Chances website to include smoking status as a major risk factor for mortality estimates. The new estimates provide more accurate predictions of cancer and disease risk, with smokers facing significantly higher risks after age 40.
A decision analytical model study found that sustained public health interventions can reduce opioid-related overdose deaths. Implementing medications for opioid use disorder and increasing naloxone supply were key factors in reducing death rates.
The study found that taking home methadone doses increased deaths of black and hispanic men but had little effect on the other demographic groups. Relaxing methadone restrictions may help certain at-risk groups, addressing the heterogeneity in treatment.
State palliative care laws are associated with an increased likelihood of dying at home or in hospice among decedents from cancer. Passage of these laws may be an effective policy intervention to increase the number of seriously ill patients who experience their death in such locations.
Projected health outcomes associated with Supreme Court decisions in 2022 suggest substantial harms to public health due to lack of COVID-19 workplace protections and revoked abortion rights. Nearly 3,000 excess deaths are projected over a decade.
The UCDP reported a 97% increase in deaths in armed conflicts to 237,000 in 2022, with Ethiopia and Ukraine being the deadliest conflicts. The number of active conflicts remains at a historically high level, with over 50 state-involved conflicts and 82 non-state conflicts.
A study by University of Missouri researchers found similarities in COVID-19 mortality rates between certain US states and Canadian provinces, highlighting the importance of localized public health strategies. The findings suggest that factors such as population density, age, and socioeconomic conditions may have contributed to these s...
A new American Heart Association scientific statement highlights the disproportionate burden of cardiovascular disease on AI/AN women. The study reveals that more than 60% of these women have suboptimal heart health when pregnant, increasing their risk of heart disease later in life.
Researchers found that boosting vaccine use can reduce lockdown intensity and duration, but the relationship varies based on factors like disease severity and vaccination speed. The study suggests a nuanced approach to balancing lockdowns and vaccinations in future pandemics.
A recent study published in Annals of Internal Medicine found that elderly hospitalized patients treated by physicians with MD or DO degrees had virtually identical mortality rates, readmissions, length of stay, and healthcare spending. The results suggest high-quality care regardless of the physician's educational background.
Researchers discuss chemotherapeutic resistance in recurring ovarian cancer, focusing on the unfolded protein response and its effect on polyploid giant cancer cells. Understanding this mechanism could lead to investigating cancer cell molecular mechanisms and potential therapeutic strategies.
A new study from Tulane University found that eight social determinants of health significantly contribute to the racial mortality gap in the US. The research indicates that addressing these factors can eliminate the disparity in premature deaths among Black and White adults.
A new combination treatment for brain hemorrhage significantly improves survival rates and reduces disability. The INTERACT3 study shows a Care Bundle of readily available treatments can improve outcomes, particularly in low- and middle-income countries where most cases occur.
A study of 5,813 youths found that socially vulnerable communities experienced a disproportionate number of assault-related firearm deaths. Stricter gun laws were associated with lower death rates, but disadvantaged communities remained disproportionately impacted.
A study of nearly 4,000 patients with cirrhosis found that mortality rates were more than twice as high in lower-income countries compared to high-income countries. The research highlights the need for improved access to medical care and preventive measures to address liver disease.
A comprehensive multicontinental analysis found that COVID-19 vaccination reduced mortality by 22% among hospitalized and oxygen-dependent individuals. Vaccination was particularly beneficial for vulnerable groups, such as the elderly and those with pre-existing conditions.
Researchers found that COPD patients prescribed non-benzodiazepine benzodiazepine receptor agonists (NBZRAs) like zolpidem did not have increased risk of hospitalizations or death compared to those prescribed other types of hypnotics. However, they had a greater risk of death and exacerbations when not prescribed hypnotic drugs
A retrospective analysis of patient data suggests that targeting mucus plugs in the lungs may help prevent deaths from COPD. The study found that patients with mucus plugs had a higher mortality rate compared to those without, with significant associations across different disease phases.
The number of deaths worldwide from ischemic stroke increased from 2 million in 1990 to more than 3 million in 2019, with an expected increase to nearly 5 million by 2030. Lifestyle factors such as smoking and high blood pressure are identified as major contributors to the rising stroke rate.
A new study found an initial decline in diabetes mellitus plus cardiovascular disease-related mortality, but it reversed from 2014 to 2019. The researchers emphasized the need for primary prevention of diabetes and early diagnosis to prevent cardiovascular complications and mortality.
The Black population in the US has experienced over 1.63 million excess deaths and 80 million excess years of life lost from 1999 to 2020. After initial progress, disparities between Black and White populations worsened in 2020, highlighting ongoing health inequities.
Mortality rates from diabetes and cardiovascular disease increased significantly from 2014 to 2019, with patients with diabetes mellitus disproportionately affected. Researchers emphasize the need for better population-level control of diabetes to positively impact life expectancy.
A study of 307,000 neonates with very low birth weight found that increased use of probiotics in hospitals was associated with reduced risk of necrotizing enterocolitis, but not sepsis or mortality rates. The adoption of routine probiotic use increased slowly from 2012 to 2019.
Research finds military veterans exposed to low doses of chemical warfare agents have higher rates of mortality from genitourinary diseases and deaths attributable to alcohol. However, overall cancer incidence is not significantly associated with Porton Down attendance.
A new study from the USC Norris Comprehensive Cancer Center found that immigrant adults with liver cancer have a significantly higher five-year survival rate compared to those born in the US. The study identified disparities in survival rates across different racial and ethnic groups, with immigrants demonstrating better outcomes.
An analysis of 172 countries and territories found that health worker shortages are strongly associated with higher death rates, particularly for neglected tropical diseases and maternal complications. The study highlights the need for targeted action to boost health workforces in priority areas.
A 24-year study of freshwater fish exposed to warm water pollution found changes in growth rates, death rates, and size. Despite expectations, the study revealed that warmer waters led to larger fish, contradicting general predictions of global warming's effects on natural ecosystems.
Researchers have engineered a new CRISPR-based drug candidate targeting E. coli directly while preserving the microbiome. The innovative treatment has shown promise in reducing E. coli burden in mice and is now in phase 1 clinical trials to treat blood cancer patients and prevent deadly infections.
Deaths from falls among adults aged 65 or older in the US rose between 1999 and 2020, affecting all population subgroups. The relative ranking of groups remained unchanged over time despite varying magnitudes of increase.
Fentanyl-related pediatric deaths increased substantially from 2013 to 2021, with the COVID-19 pandemic exacerbating this public health crisis. Annual deaths peaked in 2020 and 2021, indicating a more than 6-fold increase among children under 5 years.