Pairing clinician and basic science educators can help improve retention of information in medical school curriculum design. This integration, starting from the initial stages, facilitates the transfer of knowledge to clinical settings. By shadowing clinicians, basic scientists can better understand how to communicate information with ...
A new study from the University of Pennsylvania School of Nursing found that hospitals with better work environments have lower burnout rates among nurses and higher patient satisfaction. The researchers suggest that Magnet designation or similar initiatives can help improve these conditions.
A study published in Journal of the American Academy of Child and Adolescent Psychiatry found that stepwise treatment for pediatric OCD results in excellent long-term stability of treatment gains. Most participants responded well to treatment, with significant improvements in symptoms, psychosocial functioning, and depressive symptoms.
SourceElsevier·JournalJournal of the American Academy of Child & Adolescent Psychiatry·DateFeb 27, 2020
BU's PREP program supports recent bachelor's degree recipients from underrepresented groups in biomedical sciences, providing research experience and mentorship to advance their PhD training or career prospects. The five-year grant will foster diverse talent pipeline for STEM education.
Researchers discovered the anterior lateral motor cortex plays a crucial role in integrating vast amounts of information to make decisions, surpassing previous understanding of its primary function. This finding highlights the brain's remarkable ability to adapt to context and informs scientists' larger understanding of brain function.
A study published in the journal Brain found that nearly 40% of schizophrenia patients had brains similar to those of healthy people, highlighting a potential new subtype. The discovery could lead to more personalized treatment options by accounting for these differences.
Researchers found that patients with rheumatoid arthritis who had adequate folate levels were less likely to die from cardiovascular disease. The study suggests that maintaining optimal folate levels through diet and supplements could help reduce this risk in these patients.
A large study found that prenatal exposure to maternal metabolic conditions or mental health adversities increased the risk of childhood neurodevelopmental delays. The study suggests a potential therapeutic target in pregnancy to give children a healthier start in life, with antenatal intervention as a possible avenue for prevention.
A study by Stanford University School of Medicine investigators found that patients with ulcerative colitis have depleted levels of secondary bile acids and Ruminococcaceae bacteria in their intestines. These findings suggest that supplementing or restoring these missing metabolites may effectively treat intestinal inflammation.
A recent study by University of Pennsylvania School of Nursing found that while many PA school nurses have a supply of naloxone, important barriers to access and use exist. The study highlights the need for increased support and education among school nurses to improve naloxone administration in schools.
Research found that community-level LGBTQ supportiveness is associated with lower odds of lifetime substance use among sexual minority boys and girls. Living in a large population center also reduced the risk of lifetime alcohol use for boys, while a progressive political climate increased the risk of marijuana use for girls.
A study published in Circulation shows that declines in heart attacks are greatest among men, with a nearly 50% decrease between 2000 and 2014. While women also experienced a decline, their rate slowed in the last five years of the study.
A cross-sectional study in Japan compared primary care experiences in hospital-based practices and community-based office practices. Patients reported better patient experience of community orientation at community-based offices, while hospital-based practices offered better first contact experiences.
Researchers found that low oxygen levels cause abnormal sodium currents that lead to dangerous cardiac rhythms. The discovery offers new targets for therapeutics to prevent late current and arrhythmia associated with heart attacks, chronic heart failure and other life-threatening conditions.
A comprehensive molecular study has defined key genes and proteins contributing to endometrial cancer. The research suggests tailored treatments for each patient and potential biological targets for future drug design.
Survival rates have improved significantly for children who received kidney transplants, with a 72% lower mortality risk among those transplanted later than earlier periods. This improvement is primarily attributed to reduced deaths from cardiovascular causes and infections.
Researchers at Massachusetts General Hospital discovered extensive brain inflammation in veterans with Gulf War Illness, particularly in cortical regions involved in memory and reasoning. This finding may help identify new therapeutic targets for conditions linked to neuroinflammation.
Researchers at Mount Sinai discovered a novel combination of two classes of drugs that cause the highest rate of human beta cell proliferation without harming most other cells in the body. This finding is an important step toward a diabetes treatment that restores insulin production. The study, published in Science Translational Medici...
Researchers from Massachusetts General Hospital Cancer Center identified an adaptation by cancer cells that facilitates their spreading to distant sites. Targeted therapies disrupting the ribosome function and inhibiting cancer cell growth slows the spread of breast cancer in a mouse model.
Researchers developed a machine learning algorithm to predict dementia onset using electronic medical records, showing similar accuracy to invasive tests. The method could help identify patients at risk earlier, allowing for prevention and better quality of life.
Scripps Research scientists have developed a 'warp drive' method to create unique 3-D structures resembling those found in nature, which can lead to more effective medicines. The technique has potential applications for treating inflammatory diseases and may help identify new drug leads.
A new article from the Journal of Vocational Rehabilitation reveals effective but underutilized practices for including employees with disabilities in workplaces. These include partnering with disability organizations, auditing hiring practices, and providing supervisor training. The survey also found that a higher commitment from uppe...
The employment-to-population ratio for working-age people with disabilities increased from 29.8 percent in January 2019 to 30.7 percent in January 2020, up 3.0 percent or 0.9 percentage points. This gain reflects the growing strength of the labor market and suggests an upward trend for 2020.
Researchers analyzed brain tissue from patients with Alzheimer's and corticobasal degeneration, finding that modifications to the tau protein influence its misfolding behavior. The study reveals key insights into how tau filaments form, grow, and spread throughout the brain, potentially accelerating the fight against neurodegenerative ...
A new study suggests that moral and religious beliefs may exacerbate concerns about porn addiction. Researchers found that individuals who morally disapproved of pornography were more likely to report addiction, even with low or average porn use. The findings highlight the need for clinicians to consider these factors when diagnosing c...
A zinc finger domain in Arabidopsis protein SIZ1 is essential for transcriptional regulation of genes required for abiotic stress responses, including cold, salt, and drought stresses. The domain's absence leads to impaired SIZ1 function, stunted plant growth, and increased sensitivity to stressful conditions.
Researchers have developed a technology that can distinguish between Parkinson's disease and multiple system atrophy with high accuracy. The Protein Misfolding Cyclic Amplification (PMCA) test targets misfolded alpha-synuclein aggregates, allowing doctors to identify the correct disease and pursue timely treatment.
Researchers at Massachusetts General Hospital developed mathematical models to predict how tumors may respond to immunotherapy and how adding other anti-cancer drugs could lead to improved treatment. The models suggest that normalization of the tumor microenvironment, including blood supply, could improve treatment efficacy.
Researchers found that physical activity was a protective factor against diet lapses in a real-world environment study. Exercise reduced the risk of overeating by more than half when participants engaged in 60 minutes of physical activity, compared to those who didn't exercise.
The Damon Runyon Cancer Research Foundation has awarded $231,000 in funding to 16 postdoctoral scientists conducting innovative cancer research projects. The Fellowship aims to encourage promising young scientists to pursue careers in cancer research.
Researchers at Boston University School of Medicine have identified the unique genetic program behind primordial lung progenitors, a rare and transient cell type. This discovery may lead to improved stem cell protocols for treating respiratory diseases such as COPD, cystic fibrosis, and lung interstitial disease.
A new study found that between 15-22 out of every 100 Indian patients with mild-to-moderate CKD had significant impairment in at least one domain of quality of life. Lower income, poor education, and female gender were associated with lower quality of life scores.
A new study maps TB immune responses in diverse models including genetically diverse mice and blood samples from adolescents with TB. The study reveals similarities and differences between human, mouse, and macaque responses, providing valuable insights for developing effective therapies.
Researchers discovered that the darcin pheromone triggers a complex response in the brain of female mice, driving both innate and learned sexual behaviors. The study mapped the neural circuitry responsible for processing the pheromone, revealing its role in integrating sensory information with an animal's internal state.
A University at Buffalo-led research team is studying molecular interactions that enable enzymes to accelerate chemical reactions. The goal is to understand how enzymes perform their job, with a focus on enzyme activation and inhibition.
Recipients of kidney paired donation experience equivalent outcomes to those receiving kidneys from other living donors, with similar rates of organ failure and mortality. The study demonstrates the safety and effectiveness of national kidney paired donation programs in treating patients with incompatible living donors.
A team of researchers aims to improve early detection of cognitive impairment using voice assistant systems like Amazon Alexa and Google Home. They will collect data on patient participants to provide feedback to patients, caregivers, and clinicians, potentially enabling long-term planning for independence.
Research suggests that strict adherence to traditional masculine ideals can lead to more severe post-traumatic stress disorder symptoms and hinder access to effective treatment. Veterans who conform to these norms may have a harder time seeking mental health help due to societal expectations of masculinity.
A recent study by the American Psychological Association found that caregivers are more likely to neglect their own health due to cost concerns. The study revealed a significant gap in healthcare access and utilization among caregivers, with 26% having no insurance coverage compared to non-caregivers.
Researchers at the University of Pittsburgh propose a system called 'EasyPass' that uses existing wireless channels to create extra opportunities for lag-free connections in IoT devices. Lab tests demonstrate a 90% reduction in data transmission delay and up to 2.5 Mbps throughput.
Researchers found that light exposure regulates how two kinds of fat cells work together to produce energy. A lack of sunlight may lead to metabolic problems beyond seasonal affective disorder, with implications for human health.
Researchers at Kessler Foundation identified specific brain regions associated with memory rehabilitation using the modified Story Memory Technique. Participants showed decreased brain activity in language network, default mode network, and executive control network, leading to improved learning and memory outcomes.
The ISSCR is updating its guidelines to address the use of pluripotent stem cells in modeling early human embryo development. The new guidelines outline principles and recommendations for researchers, including oversight by special committees and reporting to Embryo Research Oversight (EMRO) processes.
The Society for Pediatric Research welcomes 130 new members, including renowned researchers, who will contribute to child health endeavors. The SPR's initiatives include a research and presentation forum, award programs, and career development support.
Researchers at Massachusetts General Hospital develop new non-surgical Coolsculpting method targeting fat almost anywhere in the body using a safe, injectable ice solution. The technology selectively reduces fat tissue at any depth and site accessed by a needle or catheter.
Researchers identified four ageotypes: metabolic, immune, hepatic, and nephrotic, which determine biological pathways in the body. The study also found that lifestyle changes can slow aging rates in some individuals.
Researchers identified a rare genetic syndrome, CATIFA, caused by mutation of the RIC1 gene, characterized by cleft palate, intellectual disability, facial dysmorphism, and ADHD. The study combined zebrafish models, pediatric genetic diseases, and electronic health records to define the underlying mechanism.
A landmark study published in Social Science & Medicine found that over 95% of women who had an abortion said it was the right decision for them five years later. The study also showed that negative emotions such as sadness and guilt decreased dramatically over time, while relief remained a dominant emotion.
A new study found that Medicaid expansion was associated with a six percent lower rate of total opioid overdose deaths, as well as lower rates of death involving heroin and synthetic opioids. However, unexpectedly, an 11 percent increase in methadone overdose mortality was observed with Medicaid expansion.
The Mark Foundation for Cancer Research has awarded six grants totaling $4.5 million to promising early career scientists pursuing projects in basic, translational, and clinical cancer research.
A new study published in Health Affairs found that adults in Southern states with expanded Medicaid programs experienced lower rates of physical and mental health decline compared to those without expansion. The research suggests that access to the safety net is an inadequate substitute for coverage, highlighting the need for non-expan...
A new study found that higher adherence to the Mediterranean diet is associated with a lower risk of kidney function decline and failure in transplant recipients. Those with higher Mediterranean Diet Scores experienced 29% less risk of function loss and 32% less risk of failure.
Research on fossilized fish from the late Devonian period details the evolution of fins as they began to transition into limbs. The study used CT scanning to examine fin shape and structure, constructing digital 3D models that allowed researchers to infer how fins worked and changed.
A new study reveals that one dose of the HPV vaccine may prevent infection from the potential cancer-causing virus, with implications for reducing global cancer burden. The current two- or three-dose series may be replaced by a single dose regimen if ongoing clinical trials provide sustained benefits.
The Breakthroughs in Gerontology (BIG) Awards support research into human aging and healthspan. Ursula Jakob will study early epigenetic events that extend lifespan, while Norbert Perrimon will investigate organ communication networks influencing aging.
The Glenn Foundation for Medical Research and AFAR have announced the 2019 Research Grants for Junior Faculty, awarding fifteen early career scientists $1,450,000 to support research on aging processes and age-related diseases. The grants aim to translate basic biology into interventions that can extend healthspan with lifespan.
The American Federation for Aging Research and the Glenn Foundation for Medical Research announced ten fellowships awarded to postdoctoral researchers to study basic biology of aging. The program aims to develop independent research projects to build knowledge in aging, potentially leading to therapies and interventions.
A new study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that computer-based attention training reduced anxiety in 50% of participants. The treatment involved targeting neutral or threatening stimuli, leading to comparable reductions in anxiety. This promising result provides a potential aug...
SourceElsevier·JournalJournal of the American Academy of Child & Adolescent Psychiatry·DateDec 19, 2019
A recent analysis reveals higher mortality rates among Hispanic and Asian patients undergoing dialysis in the US territories compared to their counterparts in the 50 US states. The study highlights the need for research into potential kidney disease-related disparities in these territories.
Seven postdoctoral fellows have received awards of $120,000 for two years to study the role of endothelial senescence on age-related cognitive decline and other topics. The Irene Diamond Fund/AFAR program provides full-time research training and flexible grant support to senior postdoctoral fellows.