Articles tagged with Memory Disorders
A new study reveals that girls with NF1 are at greater risk of vision loss from brain tumors, while boys are more vulnerable to learning disabilities. The research identifies gender-linked differences in male mice that may help explain these findings.
Increased inflammation after infections impairs brain's ability to form spatial memories by disrupting neural circuits involved in learning and memory. The study used PET scans to measure effects of inflammation on glucose consumption in the brain, revealing a decrease in glucose metabolism in the Medial Temporal Lobe.
Researchers at Cleveland Clinic have identified a critical role for the Neuroligin-1 protein in Alzheimer's-related memory loss, disrupting synaptic networks and leading to memory decline. The discovery may provide new approaches for preventing and treating Alzheimer's disease.
A preclinical study reveals that histone deacetylase inhibitors can enhance brain's ability to replace old traumatic memories with new ones, offering promising avenues for treating PTSD and anxiety disorders. Exposure-based therapy can be combined with HDACis to improve treatment for enduring traumatic memories.
Researchers at MIT have discovered a potential new treatment for PTSD by using an HDAC2 inhibitor to make brain memories more malleable. This approach may be more effective than traditional psychotherapy alone in treating patients with well-established traumatic memories.
A recent study published in Neurology found that heavy drinking in middle age is associated with faster decline in all areas of cognitive function in men. Moderate drinking, on the other hand, may not harm memory and executive function.
A recent study published in Experimental Gerontology found that various forms of vitamin E, including tocopherols and tocotrienols, play a role in memory processes. The study revealed that higher total serum levels of vitamin E, particularly γ-tocopherol and β-tocotrienol, were associated with a reduced risk of cognitive impairment.
A new study suggests that a history of concussion may be related to the buildup of Alzheimer's-associated plaques in the brain. In people with memory and thinking problems, higher levels of amyloid plaques were found compared to those without head trauma.
A study by researchers from the University of Basel found that individuals with high motor excitability have better working memory than those with low excitability. The research used transcranial magnetic stimulation to measure motor cortical excitability and its correlation with working memory performance, revealing a positive correla...
Research suggests that breast cancer ads can be ineffective when they emphasize a woman's vulnerability, leading to motivated forgetting. This phenomenon occurs when people feel threatened about their gender or social identity, causing them to suppress memories of the ad and its message.
Researchers from East China Normal University discovered NMDA receptor 2B subunit gene expression declines significantly associated with memory impairment in aged animals. The study identified key regulatory pathways, including P53 and insulin-like growth factor pathways.
A study by Dr. Sha Liu and colleagues found that progesterone administration can reverse cognitive impairment in Alzheimer's disease patients. The research, published in Neural Regeneration Research, used rat models to demonstrate the protective effect of progesterone against Aβ25–35-induced neurotoxicity.
Researchers found that pre-moxibustion prior to Aβ1–42 exposure was more effective than moxibustion after Aβ1–42 exposure in protecting neuronal structure and lowering apoptosis rate. Moxibustion therapy may have a beneficial effect on preventing Alzheimer's disease development.
A team of Montréal researchers discovered that the protein PC7 plays a critical role in the brain by affecting cognitive performance such as anxiety, learning, and emotional memory. The study found that mice lacking PC7 had impaired episodic and emotional memories, while exhibiting increased levels of dopamine in the brain.
A randomized controlled trial found that a modified Story Memory Technique (mSMT) improved learning and memory in people with MS, leading to better daily functioning and increased satisfaction. The effects persisted for six months, providing first Class 1 evidence for cognitive rehabilitation in MS.
Researchers found that antioxidant extracts from spearmint and rosemary reduce deficits in mild cognitive impairment, a precursor to Alzheimer's disease. The study suggests these herbal compounds might have beneficial effects on altering age-associated cognitive decline.
A new study found that aerobic exercise improves memory, brain health, and physical fitness in healthy aging adults. Researchers used non-invasive brain imaging techniques to detect brain changes earlier, revealing increased blood flow to the hippocampus and anterior cingulate region.
Research reveals new roles for sex hormones like estrogen in the cognitive function of females, including memory and interpreting social cues. Estrogen replacement therapy may help prevent stress-related memory loss in post-menopausal women.
Researchers found aerobic exercise increases hippocampal volume, improves memory, and enhances connectivity in individuals with MS. Aerobic exercise resulted in significant benefits for memory but not other cognitive functions.
A new study found that people with lower blood sugar levels performed better on memory tests, even within the normal range. Higher blood sugar levels were associated with smaller brain volumes and poor memory performance.
Research reveals that a genetic variation in the ADRA2B gene affects how well antidepressants like reboxetine weaken negative memory recall in healthy men. The study found that individuals with the variant gene form recalled more negative memories, regardless of treatment.
Researchers at the University of Basel have identified a new compound that reduces aversive memory, a trait central to anxiety disorders like PTSD. The compound, a known antihistamine, was found to significantly reduce memory recall of negative pictures but not neutral or positive ones.
Researchers at RIKEN-MIT Center for Neural Circuit Genetics have uncovered a faulty brain mechanism underlying schizophrenia and other psychiatric disorders in humans. Mice genetically engineered to display symptoms of schizophrenia exhibit abnormal neural activity in the default mode network, which processes memories and recall.
Research confirms GWI deficits in working memory, a critical cognitive function that enables short-term retention of information. Brain alterations reveal a unique neurobiological marker that could positively identify GWI, with potential implications for Alzheimer's disease treatment.
Neurological researchers have discovered a significant link between abdominal fat and memory loss, finding that the same protein controlling fat metabolism in the liver also resides in the memory center of the brain. This study suggests that people with high levels of abdominal fat may be at risk for memory-related problems later in life.
Researchers have found that a selective GABA inverse agonist can potentiate learning and memory performances in mice with Down's syndrome, reversing learning impairments. The drug also restored normal levels of gene expression in disregulated pathways, suggesting its therapeutic potential.
Researchers found that osteocalcin, a bone-derived hormone, plays a powerful role in prenatal brain development and cognitive functions such as learning, memory, anxiety, and depression. Osteocalcin promotes the birth of neurons, increases neurotransmitter synthesis, and affects behavior in adult mice.
Researchers found that pravastatin impaired learning and recognition memory in rats, while atorvostatin showed no adverse effects. The study suggests chronic treatment with pravastatin may cause cognitive impairment, but further studies are needed to confirm this.
A systematic questionnaire has been devised and evaluated to identify pre-school children with an increased risk of long-term post-traumatic disorders within a few days of an accident. The questionnaire recorded high accuracy, identifying 85% of children who would later develop PTSD.
Researchers discovered that beta-amyloid destroys synapses by binding to a receptor called PirB, leading to a cascade of biochemical activities. The study suggests that Alzheimer's disease starts to manifest long before plaque formation becomes evident, offering new hope for earlier treatments.
A new, environmentally-friendly electronic alloy consisting of 50 aluminum atoms bound to 50 atoms of antimony may be promising for building next-generation 'phase-change' memory devices. The material has high thermal stability and can store three bits of data in a single memory cell.
Computer scientists at the University of Texas at Austin have created a new method for summarizing hours of wearable camera footage into short, meaningful stories. The 'story-driven' video summarization technique uses machine learning to analyze recorded videos and assemble a better summary than existing methods.
Experts warn that UK and US policies to screen for pre-dementia may lead to unnecessary investigation and treatment. Up to 65% of people aged over 80 may be incorrectly diagnosed with Alzheimer's disease.
A new study links obstructive lung disease to impaired cognitive functions, including memory and information processing. Researchers analyzed 5,764 people with OLD and found significant declines in memory tests, pairs matching tests, and reaction time.
Researchers at UC Irvine have created new memories by directly altering brain cells in the cerebral cortex, producing specific memory content with long-term retention. This breakthrough could lead to new treatments for learning and memory disorders.
A team of neuroscientists found that better coordination between two brain regions is associated with less forgetting and longer-lasting memories. The study suggests that the brain strengthens memories by distributing them across networks, a process that takes time.
A study at Columbia University Irving Medical Center identifies RbAp48 as a significant contributor to age-related memory loss, which can be reversed. The researchers found that RbAp48 plays an active role in the process and propose it as a target for therapeutic intervention.
Researchers found that CTE primarily affects behavior and mood, while memory and thinking abilities are also impacted. The study suggests that athletes with CTE experience symptoms at a younger age, with mood/behavior problems appearing at an average age of 35.
A study of 36 male athletes with chronic traumatic encephalopathy (CTE) found that the disease initially affects behavior or mood and later impacts memory and thinking abilities. The researchers discovered notable differences in symptoms between those experiencing behavior problems and those with memory and thinking issues.
A new study published in Neurology suggests that high-altitude flying increases the risk of brain lesions. The research found that pilots had nearly four times the volume and three times the number of brain lesions as non-pilots, with lesions evenly distributed throughout the brain.
Ketamine use in pediatric anesthesia may lead to long-term cognitive and behavioral problems in young children. Research suggests that ketamine's neurotoxic effects, particularly tau phosphorylation, can damage developing neurons and microtubule function.
Researchers at Neuroscience Research Australia discovered that the orbitofrontal cortex plays a key role in linking emotion and memories in frontotemporal dementia patients. This finding explains why FTD patients struggle to recall emotionally charged events, highlighting new potential for diagnostic tools.
A study by UCLA researchers found that older adults who used the Dakim BrainFitness program demonstrated significant improvements in both immediate and delayed memory skills, as well as language abilities. The findings suggest that computerized brain training can be an effective way to improve cognitive skills in this age group.
A study by McGill University researchers found that blocking the activity of a specific receptor can reverse memory pathology and improve cerebrovascular function in mice with advanced Alzheimer's disease. The treatment also reduced toxic amyloid-beta peptide levels, which contribute to neuronal and vascular dysfunction.
A new study published by The Endocrine Society found that weight loss improves memory function in older, overweight women. After six months of dieting, their brain activity changed in the regions important for memory tasks, with improved performance and altered brain activity detected.
Researchers at McMaster University found that women's ability to recall faces is superior to men's, likely due to their subconscious focus on facial features. By changing their eye movement patterns, individuals can potentially improve their own face memory and recognition skills.
Tel Aviv University researchers used a method to modify the levels of the protein tomosyn in the mouse hippocampus, leading to a decline in learning and memorization abilities. The study suggests that adjusting tomosyn levels may help increase cognition and combat memory loss in Alzheimer's patients.
Research suggests that sleep plays a crucial role in consolidating emotional memories in healthy children but not those with attention-deficit hyperactivity disorder (ADHD). Brain activity during sleep may exacerbate emotional problems in children with ADHD.
Dr. Shayna Rosenbaum's research focuses on the neural bases of learning and memory, particularly in patients with memory impairment. Her work has provided a framework for understanding how memory is organized in the brain and the efficacy of intervention techniques when memory declines or fails.
Activating Sirtuin 1 (SIRT1) enzyme delays nerve cell loss and preserves cognitive function in mice. Reducing caloric intake also produces similar effects.
A study of 3,690 older adults found that even short-term use of strong anticholinergics causes memory problems. Taking multiple drugs with weaker anticholinergic effects also has a negative impact on cognition over time.
A recent study suggests that age-related atrophy of the medial temporal lobe (MTL) may contribute to difficulties in processing and remembering everyday events. The researchers found that older adults with MTL atrophy performed poorly in separating and chunking events, which can impact memory for everyday activities.
A new study from Wake Forest Baptist Medical Center shows that regular exercise does not worsen the pain associated with fibromyalgia and may even improve symptoms. The study found that participants who engaged in moderate-intensity exercise for at least 12 weeks showed greater improvements in clinical symptoms.
A multicenter study reveals that mild traumatic brain injury after blast exposure produces inflammation and oxidative stress, similar to disorders of memory processing such as Alzheimer's disease. Gene activity patterns akin to neurodegenerative diseases were also observed in the brains of rats exposed to a shock tube.
A team of neuroscientists studied the case of EP, a man with radical memory loss due to viral encephalitis. Unlike HM, who retained some residual tissue, EP's brain damage resulted in total destruction of specific memory-linked structures, rendering him unable to learn new information.
Researchers at UTHealth used sea snail nerve cells to demonstrate a strategy for overcoming memory deficits. By retraining the cells with optimized training schedules, they reversed memory loss and restored connection strength.
Researchers at the University of Missouri found that propranolol improves working memory performance in people with Autism Spectrum Disorder. The study showed significant improvements in working memory abilities, particularly in those who already take the medication for anxiety.
A review of 32 randomized controlled trials suggests that mental exercise, such as computerized training programs or intensive one-on-one personal cognitive training, may benefit older adults in preventing cognitive decline. The annual rate of dementia-related cognitive decline is estimated to double to over 1 million Canadians by 2047.
A new study found that heart disease risk scores may be more useful in predicting future decline in cognitive abilities, or memory and thinking, than a dementia risk score. The study involved 7,830 participants and showed stronger links between heart disease risk and cognitive decline.
Researchers have identified a key molecule responsible for triggering chemical processes in the brain linked to memory formation. The study found that the gene CASK regulates the 'molecular memory switch', enabling it to remain active even after calcium has gone, paving the way for new therapies to reverse memory loss.