Articles tagged with Memory Disorders
Researchers altered a gene in mice to inhibit PDE4B, leading to enhanced cognitive abilities and reduced anxiety. The findings offer hope for better treatments for age-related cognitive decline, Alzheimer's disease, and schizophrenia.
A study by Northwestern University researchers found an intrinsic biological difference in the molecular regulation of synapses in the hippocampus between males and females. The drug URB-597 increased inhibitory effect in females, causing a decrease in neurotransmitter release, but had no effect in males.
Researchers at the University of Basel used computational models to describe human memory processes for the first time. The study identified specific genetic profiles underlying distinct mental processes, such as learning and memory storage.
Researchers from Cardiff University identified a process in the brain that can help rescue lost memories or bury bad ones. They found that strong reminders can recover memories previously thought to be lost in rats.
Researchers discovered insulin delivered via nasal cavity reaches affected brain areas, improving memory in a mouse model. The study suggests potential future treatments using gastrointestinal hormones like insulin to combat Alzheimer's disease.
A new Iowa State University study found a strong association between insulin resistance and memory function decline, increasing the risk for Alzheimer's disease. Insulin resistance is common in people who are obese, pre-diabetic or have Type 2 diabetes, and can lead to cognitive decline at any age.
A study published in Cortex found that sleep significantly improves memory accessibility, allowing subjects to recall facts they couldn't remember while awake. After a night's sleep, participants were able to recover unrecalled memories, suggesting that sleep sharpens and makes memories more vivid and accessible.
Researchers found that people with schizophrenia experience relational encoding problems and regional brain dysfunction in the dorsolateral prefrontal cortex and hippocampus. The study suggests a new target area for treatment development to improve memory in individuals with psychosis.
A meta-analysis of 53 studies involving nearly 8,500 people found that programs featuring violence and sex don't improve advertising effectiveness, while some nuances were discovered, such as improved ad recall when the content matches the media.
Researchers found evidence of Alzheimer's-like pathologies in individuals with the APOE ε4 variant, including increased amyloid plaque and tau levels. This study provides a foundation for further research among patients at risk of Alzheimer's earlier than usual.
A new study shows that stroke survivors experience accelerated and persistent declines in thinking ability over the years after their stroke, even after accounting for normal brain aging. The study suggests a need for better long-term follow-up care for stroke survivors to manage their cognitive problems.
Researchers found that playing Tetris after reactivating traumatic memories reduces their occurrence over time. The study suggests a potential preventative treatment for PTSD by bringing back traumatic memories under controlled conditions.
Researchers identified individual neurons in the medial temporal lobe that changed their firing to encode new associations at the exact moment of the experience. This finding may lead to a better understanding of memory loss and new methods to fight it in Alzheimer's and other neurological diseases.
A study published in Neuropsychopharmacology found that cortisol enhances the consolidation of emotional memories, particularly in individuals with anxiety and Post-Traumatic Stress Disorder (PTSD). Cortisol levels can strengthen memories of traumatic experiences during both initial formation and reconsolidation after memory retrieval.
Scientists from Scripps Research Institute have identified five microRNAs that are necessary for memory formation, while others decrease it, affecting neuronal physiology and nervous system development. The study provides valuable insights into the complex mechanisms of learning and memory.
A new University of Michigan study suggests that napping may be an effective strategy to counteract impulsive behavior and boost tolerance for frustration. The study found that taking a nap increased participants' ability to persevere through difficult tasks.
A new study found that errors on memory and thinking tests may signal Alzheimer's disease up to 13-18 years before the disease can be diagnosed. Those who scored lower overall had an increased risk of developing the disease, with higher scores associated with a lower risk.
Researchers have found that artificially reactivating positive memories can suppress the effects of stress-induced depression in mice. The study reveals how brain circuits interact with negative experiences and provides a potential target for therapeutic approaches.
Researchers found an association between cholesterol-lowering drugs and memory loss in the initial 30 days following medication initiation. The link may be due to increased contact with physicians among users of these medications, leading to earlier detection of memory issues.
A large study of nearly one million patients found that statin drugs do not likely cause short-term memory loss. Statins have been reported to cause memory lapses by some users, leading to their cessation, but the study suggests this is due to detection bias rather than a true effect of the drug.
Research at UMass Amherst finds that despite concussion-related abnormalities in sleep and memory, sleep aids recall and benefits are comparable to those without TBI. Participants who slept showed better recall in word memorization tasks compared to those tested after an equal period awake.
A study published in Nature Neuroscience found a link between poor sleep and the accumulation of beta-amyloid protein, which is believed to trigger Alzheimer's disease. Researchers discovered that excessive sleep disturbances can lead to impaired long-term memory consolidation.
A study published in Scientific Reports reveals a direct link between amyloid-beta protein and memory loss in healthy brains, even before physical signs of degeneration appear. The research found that administering amyloid-beta to pond snails caused significant impaired memories, despite no visible brain damage.
A study of retired NFL players found that those with a history of concussion were more likely to experience brain atrophy and impaired memory. The research suggests a potential link between repeated concussions and long-term cognitive decline.
New research from Griffith University uncovers significant genetic changes in receptors associated with immunological and cellular function, potentially shedding light on CFS/ME. The findings contribute to a deeper understanding of the complex illness's pathology.
A new study by the American Academy of Neurology suggests that professionals with jobs requiring strategic thinking, conflict resolution, and managerial tasks may experience better brain protection against memory and thinking decline. Participants with higher levels of these tasks showed slower cognitive decline rates over eight years.
Researchers found that simultaneous inhibition of multiple Class 1 HDACs led to improved memory restoration and synaptic growth in animal models of Alzheimer's disease. The study suggests a promising new therapeutic strategy for the treatment of this devastating neurodegenerative disorder.
A Washington, D.C., researcher has received a $130,000 award to investigate temporal lobe epilepsy and its impact on memory processing. The two-year fellowship will support the development of a standard method for using imaging scans to evaluate patients' memory functioning before surgery.
A new study found that people with more challenging jobs may live up to three years longer than those with less skilled jobs after developing frontotemporal dementia. The cognitive reserve theory suggests that higher occupational levels build connections in the brain, creating a buffer against disease.
A new study reveals cannabis consumers have a less active hippocampus and are more susceptible to false memories. Chronic use of cannabis can accentuate age-related memory problems.
Cognitive scientists identified three middle-aged adults with SDAM, who lack personal recollection of past events but can learn and recall information normally. Brain imaging revealed reduced vividness and activation in midline brain regions, as well as a subtle volume reduction in the hippocampus.
UCI MIND has been redesignated as an Alzheimer's Disease Research Center, allowing it to continue its impactful clinical and basic research programs. The center involves over 100 investigators studying the cellular, molecular, and clinical risk factors of Alzheimer's disease.
A new study published in Neurology suggests that heavy snoring and sleep apnea may be linked to an earlier age of memory decline. Treating the disorders with a breathing machine may delay the decline, according to the research.
NTU scientists have discovered a new treatment for dementia using deep brain stimulation, which can form new brain cells and improve memory retention. The research found that stimulating the front part of the brain led to increased brain cell growth, reducing anxiety and depression, and promoting improved learning.
In a groundbreaking study, researchers used optogenetics to artificially associate the memory of a foot shock with an unrelated environment, triggering increased fear-related behavior. The findings suggest that co-activated cell ensembles can link two distinct memories, paving the way for new treatments of psychiatric disorders.
A new scoring system helps determine which elderly people are at higher risk of developing memory and thinking problems that can lead to dementia. Factors such as years of education, history of stroke or diabetes, and smoking contribute to the risk score.
Researchers at Johns Hopkins University found that a novel therapeutic approach using an existing drug reverses hyperactivity in the brain of patients with amnestic mild cognitive impairment (aMCI), a condition that increases risk for Alzheimer's dementia. The therapy, calmed hyperactivity in the brain and improved memory performance.
Researchers at Vanderbilt University discovered a specific region of the brain that signals when a memory is being retrieved with high detail, enabling the prediction of recall order. This finding has significant implications for understanding and preserving memories in individuals with diseases like Alzheimer's.
Research proposes that a brain system called declarative memory compensates for autism, OCD, and dyslexia by providing strategies to overcome learning difficulties. This compensation allows individuals to learn scripts for social situations and control tics and compulsions.
Researchers at USC's Keck School of Medicine have identified a promising avenue for treating Alzheimer's disease by rebalancing the immune response to clear toxic plaques from the brain. The study found that blocking a specific substance can activate an immune response to restore memory loss and brain cell damage.
Researchers from Texas A&M University have discovered a compound called resveratrol that may help improve memory function in older adults. Studies have shown that treatment with resveratrol can increase neurogenesis and improve blood flow to the brain, leading to better cognitive function.
A study assessing neurocognitive functioning in 1,500 homeless adults found nearly three-quarters to have cognitive deficits. Cognitive remediation practices need improvement for this population, with adaptations required in treatment and support options.
Researchers at Gladstone Institutes discovered a new memory regulator in astrocytes, which improved memory in healthy mice and prevented impairments in Alzheimer's disease models. The study suggests that targeting A2A adenosine receptors may offer a potential treatment for improving memory.
Researchers examined 50 years of sleep research to investigate whether improving sleep early in life can delay or reverse age-related changes in memory and thinking. The findings suggest that sleeping well in middle age predicted better mental functioning 28 years later.
A recent study suggests that brain circuitry for fear retrieval shifts over time, potentially worsening symptoms of anxiety disorders. The discovery could change scientists' view of post-traumatic stress disorder and inform the development of new treatments.
A recent review of 25 clinical trials with over 47,000 participants found no significant link between statin use and changes in cognition. The study's findings contradict the US Food and Drug Agency's warning about potential cognitive adverse effects of statins.
Researchers at the Center for BrainHealth found individuals with depressed mood experience 12% memory deficit when exposed to depressive thoughts. The study suggests therapeutic approaches teaching cognitive inhibition may be effective in treating depression-related cognitive deficits.
A study found that premature birth impairs a subtle but important aspect of memory: recalling context, such as what, when, and where. The hippocampus region is smaller in preterm children, affecting contextual recollection-based retrieval.
Adults who lose all their teeth show significant declines in memory and walking speeds compared to those with some teeth. The association between tooth loss and decline remains after adjusting for various factors.
Researchers from Scripps Florida are investigating microRNAs as a potential key to treating posttraumatic stress disorder (PTSD) by erasing traumatic memories without altering other, more benign ones. The study aims to understand how the brain stores toxic memories and develop new targets to selectively target harmful memories.
Researchers identified specific circuits in the brain where memories are generated, using a precision MRI technique that tracked information flow within the brain. The study aims to gain new insights into how Alzheimer's disease affects the brain and memory processing.
A large international study has discovered two common genetic variants associated with memory performance. The findings, published in Biological Psychiatry, suggest that these genetic variants may play a role in the development of age-related memory decline and dementia.
A Penn-led team discovered that a specific set of cells in the brain are responsible for memory problems after sleep loss. By increasing levels of a signaling molecule, they prevented mice from having memory deficits.
Researchers found that even brief oxycodone exposure can impair cognitive flexibility in rats, leading to maladaptive decision-making. The study suggests that this 'cognitive hangover' may contribute to drug addiction.
Researchers at Stanford University have identified a brain structure that plays a crucial role in learning and memory, which becomes disrupted when the circadian clock is out of sync. The study found that surgically removing the suprachiasmatic nucleus (SCN) from Siberian hamsters restored their memory abilities.
Researchers developed an advanced imaging system to identify cells storing memory in a tiny worm, offering a new way to investigate molecular substrates of memory. The study may lead to understanding how memory loss occurs in humans and potentially develop therapies for memory disorders.
Scientists have identified new therapeutic targets for memory disorders and developed a high-throughput screening test to uncover compounds that may treat these conditions. The study reveals the importance of kinesin proteins in regulating synaptic function and identifies potential drug candidates.
A genetic variant associated with better memory performance was found in a large analysis of genomic data and memory test results from over 14,000 older adults. The researchers discovered that the gene FASTKD2 has not been linked to cognition before, but the G nucleotide variant showed a correlation with improved episodic memory.
A new study published in Neurology suggests that taking vitamin B12 and folic acid supplements may not reduce the risk of memory and thinking problems. The study involved 2,919 people with high blood levels of homocysteine and found no significant difference between those who took supplements and those who did not.
Researchers at University of California, San Diego, have removed the brain area responsible for spatial navigation in rats, showing that other memory abilities remain intact. The study provides insights into Alzheimer's disease and stroke effects on the brain's navigational system.