New research from Griffith University uncovers significant genetic changes in receptors associated with immunological and cellular function, potentially shedding light on CFS/ME. The findings contribute to a deeper understanding of the complex illness's pathology.
A new study by the American Academy of Neurology suggests that professionals with jobs requiring strategic thinking, conflict resolution, and managerial tasks may experience better brain protection against memory and thinking decline. Participants with higher levels of these tasks showed slower cognitive decline rates over eight years.
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Researchers found that simultaneous inhibition of multiple Class 1 HDACs led to improved memory restoration and synaptic growth in animal models of Alzheimer's disease. The study suggests a promising new therapeutic strategy for the treatment of this devastating neurodegenerative disorder.
A Washington, D.C., researcher has received a $130,000 award to investigate temporal lobe epilepsy and its impact on memory processing. The two-year fellowship will support the development of a standard method for using imaging scans to evaluate patients' memory functioning before surgery.
A new study found that people with more challenging jobs may live up to three years longer than those with less skilled jobs after developing frontotemporal dementia. The cognitive reserve theory suggests that higher occupational levels build connections in the brain, creating a buffer against disease.
A new study reveals cannabis consumers have a less active hippocampus and are more susceptible to false memories. Chronic use of cannabis can accentuate age-related memory problems.
Cognitive scientists identified three middle-aged adults with SDAM, who lack personal recollection of past events but can learn and recall information normally. Brain imaging revealed reduced vividness and activation in midline brain regions, as well as a subtle volume reduction in the hippocampus.
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UCI MIND has been redesignated as an Alzheimer's Disease Research Center, allowing it to continue its impactful clinical and basic research programs. The center involves over 100 investigators studying the cellular, molecular, and clinical risk factors of Alzheimer's disease.
A new study published in Neurology suggests that heavy snoring and sleep apnea may be linked to an earlier age of memory decline. Treating the disorders with a breathing machine may delay the decline, according to the research.
NTU scientists have discovered a new treatment for dementia using deep brain stimulation, which can form new brain cells and improve memory retention. The research found that stimulating the front part of the brain led to increased brain cell growth, reducing anxiety and depression, and promoting improved learning.
In a groundbreaking study, researchers used optogenetics to artificially associate the memory of a foot shock with an unrelated environment, triggering increased fear-related behavior. The findings suggest that co-activated cell ensembles can link two distinct memories, paving the way for new treatments of psychiatric disorders.
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A new scoring system helps determine which elderly people are at higher risk of developing memory and thinking problems that can lead to dementia. Factors such as years of education, history of stroke or diabetes, and smoking contribute to the risk score.
Researchers at Johns Hopkins University found that a novel therapeutic approach using an existing drug reverses hyperactivity in the brain of patients with amnestic mild cognitive impairment (aMCI), a condition that increases risk for Alzheimer's dementia. The therapy, calmed hyperactivity in the brain and improved memory performance.
Researchers at Vanderbilt University discovered a specific region of the brain that signals when a memory is being retrieved with high detail, enabling the prediction of recall order. This finding has significant implications for understanding and preserving memories in individuals with diseases like Alzheimer's.
Research proposes that a brain system called declarative memory compensates for autism, OCD, and dyslexia by providing strategies to overcome learning difficulties. This compensation allows individuals to learn scripts for social situations and control tics and compulsions.
Researchers at USC's Keck School of Medicine have identified a promising avenue for treating Alzheimer's disease by rebalancing the immune response to clear toxic plaques from the brain. The study found that blocking a specific substance can activate an immune response to restore memory loss and brain cell damage.
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Researchers from Texas A&M University have discovered a compound called resveratrol that may help improve memory function in older adults. Studies have shown that treatment with resveratrol can increase neurogenesis and improve blood flow to the brain, leading to better cognitive function.
A study assessing neurocognitive functioning in 1,500 homeless adults found nearly three-quarters to have cognitive deficits. Cognitive remediation practices need improvement for this population, with adaptations required in treatment and support options.
Researchers at Gladstone Institutes discovered a new memory regulator in astrocytes, which improved memory in healthy mice and prevented impairments in Alzheimer's disease models. The study suggests that targeting A2A adenosine receptors may offer a potential treatment for improving memory.
Researchers examined 50 years of sleep research to investigate whether improving sleep early in life can delay or reverse age-related changes in memory and thinking. The findings suggest that sleeping well in middle age predicted better mental functioning 28 years later.
A recent study suggests that brain circuitry for fear retrieval shifts over time, potentially worsening symptoms of anxiety disorders. The discovery could change scientists' view of post-traumatic stress disorder and inform the development of new treatments.
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A recent review of 25 clinical trials with over 47,000 participants found no significant link between statin use and changes in cognition. The study's findings contradict the US Food and Drug Agency's warning about potential cognitive adverse effects of statins.
Researchers at the Center for BrainHealth found individuals with depressed mood experience 12% memory deficit when exposed to depressive thoughts. The study suggests therapeutic approaches teaching cognitive inhibition may be effective in treating depression-related cognitive deficits.
A study found that premature birth impairs a subtle but important aspect of memory: recalling context, such as what, when, and where. The hippocampus region is smaller in preterm children, affecting contextual recollection-based retrieval.
Adults who lose all their teeth show significant declines in memory and walking speeds compared to those with some teeth. The association between tooth loss and decline remains after adjusting for various factors.
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Researchers from Scripps Florida are investigating microRNAs as a potential key to treating posttraumatic stress disorder (PTSD) by erasing traumatic memories without altering other, more benign ones. The study aims to understand how the brain stores toxic memories and develop new targets to selectively target harmful memories.
Researchers identified specific circuits in the brain where memories are generated, using a precision MRI technique that tracked information flow within the brain. The study aims to gain new insights into how Alzheimer's disease affects the brain and memory processing.
A large international study has discovered two common genetic variants associated with memory performance. The findings, published in Biological Psychiatry, suggest that these genetic variants may play a role in the development of age-related memory decline and dementia.
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A Penn-led team discovered that a specific set of cells in the brain are responsible for memory problems after sleep loss. By increasing levels of a signaling molecule, they prevented mice from having memory deficits.
Researchers developed an advanced imaging system to identify cells storing memory in a tiny worm, offering a new way to investigate molecular substrates of memory. The study may lead to understanding how memory loss occurs in humans and potentially develop therapies for memory disorders.
Researchers found that even brief oxycodone exposure can impair cognitive flexibility in rats, leading to maladaptive decision-making. The study suggests that this 'cognitive hangover' may contribute to drug addiction.
Researchers at Stanford University have identified a brain structure that plays a crucial role in learning and memory, which becomes disrupted when the circadian clock is out of sync. The study found that surgically removing the suprachiasmatic nucleus (SCN) from Siberian hamsters restored their memory abilities.
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A new study published in Neurology suggests that taking vitamin B12 and folic acid supplements may not reduce the risk of memory and thinking problems. The study involved 2,919 people with high blood levels of homocysteine and found no significant difference between those who took supplements and those who did not.
Scientists have identified new therapeutic targets for memory disorders and developed a high-throughput screening test to uncover compounds that may treat these conditions. The study reveals the importance of kinesin proteins in regulating synaptic function and identifies potential drug candidates.
A genetic variant associated with better memory performance was found in a large analysis of genomic data and memory test results from over 14,000 older adults. The researchers discovered that the gene FASTKD2 has not been linked to cognition before, but the G nucleotide variant showed a correlation with improved episodic memory.
Researchers at University of California, San Diego, have removed the brain area responsible for spatial navigation in rats, showing that other memory abilities remain intact. The study provides insights into Alzheimer's disease and stroke effects on the brain's navigational system.
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University of Toronto researchers found that anesthetics activate memory-loss receptors in the brain, leading to long-term effects on memory-related tasks. The study suggests that anesthetics may compound existing issues with sleep, new environments, and medications after surgery.
A new study found that general anesthesia impairs memory in mice by increasing the activation of α5GABA(A) receptors, leading to reduced synaptic plasticity. Inhibition of these receptors reversed memory defects in animals given anesthesia, suggesting a potential treatment for post-anesthesia cognitive impairment.
Long-term shift work is associated with impaired brain function, including lower memory and processing speed. Recovery may take at least five years after stopping shift work.
Researchers at UT Dallas' Center for Vital Longevity found that brain networks become less segregated and specialized as we age, leading to poor long-term memory. This study may lead to new clinical diagnostic criteria for age-related memory disorders.
Researchers at Columbia University Irving Medical Center found that dietary flavanols can improve cognitive function and reverse age-related memory decline in healthy adults. The study showed noticeable improvements in the function of a specific brain region and significant performance on a memory test.
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A study by the University of Manchester and Liverpool John Moores University found that courts imposed excessive and arbitrary punishments during the 2011 English riots. The research suggests that both courts and law enforcement agencies were influenced by a desire to restore order, leading to a 'collective hysteria' approach.
A new study found that smoking status significantly influences neurocognitive recovery in treatment-seeking alcohol-dependent individuals. Active-smoking ALC showed poorer recovery than never-smoking ALC on measures of learning and processing speed, while former-smoking ALC recovered less than never-smoking ALC on processing speed meas...
A new animal study found that a walnut-enriched diet improved learning skills, memory, and reduced anxiety in mice. The researchers suggest that walnuts' high antioxidant content may protect the brain from degeneration typical of Alzheimer's disease.
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A study reveals that distinct genetic mutations in neurodevelopmental disorders produce similar molecular effects, suggesting a one-size-fits-all therapeutic approach may be effective for conditions like seizures and ADHD. The research identifies shared molecular pathways involved in these diseases, providing new insights into their ca...
Research reveals that curiosity activates brain regions involved in learning and memory, leading to improved retention of information. Curiosity also recruits the reward system and interactions between the hippocampus and reward circuit enhance learning, suggesting new approaches for treating memory disorders.
Research suggests that people with memory issues without dementia are at higher risk of developing the disease. A 12-year study found nearly three times more likelihood of memory problems in those reporting changes, emphasizing the importance of taking such complaints seriously.
A study published in Neurology found that people who notice their memory slipping may be on to something, with 56% of participants reporting changes in their memory. The study suggests a significant window of opportunity for intervention before diagnosable problems show up, approximately 12 years after initial complaints began.
Researchers confirmed earlier findings of verbal overshadowing, where witnesses' descriptions impair their ability to select a suspect. The study found smaller effects in replications, suggesting sample sizes may have been too small to detect the effect reliably.
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Kessler Foundation researchers have discovered a link between slowed processing speed and executive deficits in people with multiple sclerosis. The study found that slower processing speed accounted for the observed executive function deficits, suggesting a potential target for cognitive rehabilitation strategies.
A team from the University of Pennsylvania School of Medicine found that some behavioral defects in NF1 fish are not related to abnormal Ras, but can be corrected by drugs targeting another signaling pathway controlled by cAMP. Learning and memory defects can be treated with drugs modulating the Ras pathway.
A UCI study reveals that brain inflammation can severely impact the ability to retrieve complex memories, but not simpler ones. Researchers found that immune system signaling molecules called cytokines disrupt communication among neurons in the hippocampus, leading to impaired discrimination memory.
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A recent study found that individuals with blood type AB are 82% more likely to develop cognitive impairment and dementia than those with other blood types. High levels of factor VIII, a protein related to clotting, were also linked to increased risk of memory problems.
Researchers at Tel Aviv University have discovered a new way to preserve the flexibility and resilience of the brain, targeting areas affected by Alzheimer's disease. The breakthrough involves stabilizing microtubules, which provide a cellular skeleton for nerve cells, promoting neuroplasticity.
A study suggests that the hippocampus plays a crucial role in the development of Huntington's disease cognitive decline. Researchers found increased expression of p75NTR in the hippocampus, leading to reduced dendritic spine density and memory defects.
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Researchers found that the hippocampus, a brain region essential for memory, has a bidirectional flow of activity, rather than just unidirectional. This discovery opens up new avenues for understanding neural circuitry and dynamic mechanisms controlling memory.
Researchers at Northwestern University used Transcranial Magnetic Stimulation to improve memory in healthy adults, showing that specific brain regions can be stimulated to enhance learning abilities. The study's findings have potential applications for treating conditions like Alzheimer's disease and traumatic brain injury.
A new study published in the American Journal of Alzheimer's Disease and Other Dementias found that mindfulness training can brighten outlooks on life for both individuals with memory loss and their caregivers. The training eased depression, improved sleep quality, and enhanced overall quality of life.
Researchers found an association between over-estimating medication self-administration ability and memory loss among stroke survivors. Assessing patients for their ability to estimate medication skills accurately may predict memory disorders.
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Researchers found that rule monitoring, an executive function, facilitates more accurate prospective memory in individuals with traumatic brain injury (TBI). The study identified predictors of prospective memory deficit post-TBI and highlights the importance of including rule monitoring in clinical assessments.