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Science News Archive July 2013 - Page 18


Page 18 of 31

Neurotoxicity of chemotherapy drugs

Recent studies have found chemotherapy-associated adverse neurological effects, including vascular complications and neuropathic pains. Chemotherapy triggers changes in ion channels on dorsal root ganglia, resulting in secondary changes that affect neurogenesis and plasticity.

SourceNeural Regeneration Research·JournalNeural Regeneration Research·DateJul 15, 2013

Pain control in children with cerebral palsy

A new study published in Pediatrics reveals that over 25% of children with cerebral palsy suffer from moderate to severe chronic pain, limiting their activity. Pediatricians should focus on identifying and treating the underlying causes of pain to improve health and quality of life for these children.

SourceUniversity of Toronto·JournalPEDIATRICS·DateJul 15, 2013

Fear factor: Missing brain enzyme leads to abnormal levels of fear in mice, reveals new research

Researchers found that mice lacking the monoamine oxidase A and B enzymes displayed increased fear and generalized phobia to new contexts. This study suggests a correlation between MAO enzyme deficiency and autistic-like features, highlighting potential avenues for developing interventions for neuropsychiatric disorders.

SourceUniversity of Southern California·JournalProceedings of the National Academy of Sciences·DateJul 15, 2013

JCI early table of contents for July 15, 2013

Research identifies a link between the FTO gene and increased hunger-stimulating hormone production in individuals prone to obesity. Additionally, studies show that adult brown fat levels increase with cold exposure, which may provide a new strategy for combating obesity.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJul 15, 2013

A guide to help physicians talk to their patients about dying

A new conversation guide aims to improve physicians' ability to discuss end-of-life care with patients, addressing the growing need for sensitive discussions due to an aging population and chronic illness. The guide provides practical advice on identifying high-risk patients, communicating prognosis, and clarifying patient values.

SourceMcMaster University·JournalCanadian Medical Association Journal·DateJul 15, 2013

Wayne State University scientists identify neural origins of hot flashes in menopausal women

Researchers used fMRI to investigate the neural origins of hot flashes in postmenopausal women. They found that activity in brain regions like the brain stem and insula rises before and after the hot flash, respectively. The study provides novel insights into the complex brain mechanisms underlying this common menopause symptom.

Prior flu exposure dictates your future immunity, allowing for new, rationally developed regiments

Researchers at The Wistar Institute found that sequential vaccination with distinct influenza strains can stimulate immune responses against multiple strains. This approach offers an alternative to creating a universal flu vaccine by targeting conserved regions of the virus, potentially providing long-term immunity.

SourceThe Wistar Institute·JournalJournal of Experimental Medicine·DateJul 15, 2013

Is the ice in Greenland in growing decline?

The study found that Greenland's ice sheets are losing significant amounts of ice at a rate of about 300 billion tons per year. The accelerated loss of ice mass is attributed to both anthropogenic warming and natural processes such as variations in snowfall and ocean currents.

SourceHelmholtz Association·JournalNature Geoscience·DateJul 14, 2013

Surprise finding reveals how adaptive our immune systems can be

Researchers found that people with Hyper IgE Syndrome have more redundancy in their immune systems than expected, allowing them to respond effectively to most viruses and cancers. This discovery highlights the differences between mouse model work and real human infectious diseases, providing valuable insights for clinical treatment.

SourceGarvan Institute of Medical Research·JournalJournal of Allergy and Clinical Immunology·DateJul 14, 2013

NIH scientists find that proteins involved in immunity potentially cause cancer

A set of proteins involved in the body's natural defenses produces a large number of mutations in human DNA, according to a study led by researchers at the National Institutes of Health. In some cancers, these naturally produced mutations can outnumber all other mutations and account for over two-thirds of tumors.

Antiviral enzyme contributes to several forms of cancer, University of Minnesota researchers say

Researchers at the University of Minnesota have discovered that APOBEC3B, a human antiviral enzyme, causes DNA mutations that lead to several types of cancer. The enzyme was found to be significantly elevated in six types of cancer and produced a unique mutational signature that matches the actual mutation pattern in these cancers.

SourceUniversity of Minnesota·JournalNature Genetics·DateJul 14, 2013