Researchers at Case Western Reserve University discovered a gene that helps zebrafish convert water motion into electrical impulses, similar to human hearing. The shared gene allows fish to sense water flow direction and may also inform future studies on human hair cell mechanotransduction.
Researchers develop methods to regulate robot movements and human interactions, aiming to improve social acceptance of robots in mobile robotics. The proposed control improves the robot's ability to emulate human-human dynamic behavior, reducing collisions and improving its acceptance by humans.
A recent study published in Nature found that Mars' surface water was absorbed by its crust over time, leaving the planet essentially dry. The research suggests that approximately 300 meters of surface water on Mars could have been locked up in microscopic mineral structures.
Researchers from SUTD design a versatile all-electric-controlled valley filter and demonstrate a concrete working design of valleytronic logic gate. They achieve logically-reversible computation by storing information in the electron's valley state, bypassing complex circuitries.
A new USC study reveals that tumor growth properties can influence response to cancer drugs. Researchers found certain parameters of tumor growth can forecast the effectiveness of anti-angiogenic treatment, allowing for more accurate predictions. This breakthrough has the potential to improve cancer therapy outcomes.
Scientists have determined the kinetic cycle of a potassium channel at atomic resolution, allowing for more precise targeting of specific spots within the channel structure. This breakthrough could lead to the creation of new drug molecules that can correct potassium channels dysfunction, addressing conditions such as epilepsy and diab...
Scientists have identified a common target shared by the T-cell receptors of two patients with colorectal cancer, paving the way for personalized immunotherapies. The breakthrough could lead to the development of broadly effective treatments that harness the immune system to fight cancer.
Researchers have devised a carbon-nitrogen bond forming strategy leading to new nucleoside analogues with interesting fluorescence properties, expanding on previous modifications.
A team of astronomers discovered massive clouds of gas and dust orbiting the star RZ Piscium, which could have formed from destroyed planets. The star's unusual dimming episodes suggest it is a young Sun-like star with a debris disk.
A mathematical model reveals that adding a pendulum between the container and carrying hand reduces sloshing by diminishing resonant frequency. The study shows that this design significantly reduces liquid movement, minimizing spills and burns.
Researchers at Hokkaido University have identified a cellular protein called STAP-2 that stabilizes the EGFR signaling pathway, leading to increased cell proliferation and tumor formation in prostate cancer. Suppressing STAP-2 with inhibitors could potentially treat Gefitinib-resistant prostate cancers.
A study published in the American Journal of Public Health found that Medicaid expansion led to a significant increase in early-stage cancer diagnoses, particularly among those aged 35-54. The research suggests that public health insurance may increase cancer detection, resulting in fewer cancer deaths and better patient outcomes.
Researchers propose new statistical methodology to understand climate system and attribute extreme climatic events. This approach views extreme events as a given and assesses the degree of changes in thermodynamic state variables influenced by climate change.
Researchers found that FDA-approved anti-inflammatory medications tofacitinib and ruxolitinib can block HIV production from infected cells, prevent transmission to bystander cells, and decay the viral reservoir. The study suggests using Jak inhibitors as a potential treatment for HIV-infected individuals to control the virus.
The study found that intoxicated participants spent significantly less time looking at women's faces compared to sober participants. Intoxicated men were more likely to 'check out' the body parts of women they perceived as unfriendly or unintelligent.
Researchers at the University of Michigan have created a new type of neural network made with memristors that can dramatically improve the efficiency of teaching machines to think like humans. The system, called reservoir computing, uses fewer nodes and requires less training time than traditional neural networks.
Research highlights the importance of dietary fiber in managing weight, blood sugar, and insulin sensitivity. Low-fiber diets can lead to weight gain, high blood sugar, and inflammation. Fiber supplements may help restore gut bacteria balance but more study is needed for treatment recommendations.
A study of over 1,200 Veterans with Parkinson's disease found that those receiving deep brain stimulation (DBS) lived an average of 6.3 years after surgery, compared to 5.7 years for non-DBS patients. This modest survival advantage was attributed to improved quality of life and better symptom control.
Researchers at the Max Planck Institute for Biophysical Chemistry have developed secondary nanobodies that outperform traditional antibodies in key cell-biological applications. These nanobodies can be produced in large scale by bacteria, reducing the need for animals in antibody production and improving resolution in light microscopy.
A new approach identifies and measures changes in thousands of proteins as Xenopus eggs undergo fertilization, revealing details of protein destruction and release to prevent multiple fertilization. This method enables comprehensive analyses of protein dynamics and sheds light on cellular changes driving disease.
Small Ontario municipalities are less prepared to support aging adults due to lack of planning and funding, according to a University of Waterloo report. The report recommends that municipalities adopt age-friendly policies and strategies, as seen in British Columbia, to better support their aging populations.
The observation of two neutron stars merging generated tiny ripples in spacetime called gravitational waves, detected by LIGO detectors on Earth. This event also triggered an explosion studied by hundreds of astronomers worldwide, marking a major breakthrough in astrophysics and offering new tools for observing the universe.
A high-protein diet can protect against colorectal cancer in those with inflammatory bowel disease, while a low-protein diet may be beneficial for those with a genetic predisposition. Researchers suggest tailoring treatments based on the amount of protein in the diet.
Researchers at University of Utah Health have found a way for cells to destroy viruses without harming themselves. The study reveals how the protein Dicer, which is part of normal cell function, uses a different mechanism to process viral dsRNA.
A global analysis of human birth-rate cycles found that post-holiday 'baby boom' persists across cultures, with Christmas and Eid-al-Fitr being key drivers. The study used data from Google searches and Twitter posts to reveal a correlation between online interest in sex and births nine months later.
Researchers have developed a standardized, freely available method for creating interactive 3D maps of molecules on the skin. The technique has been used to study the influence of environmental factors and health outcomes, with potential applications in forensics, agriculture, and microbiome studies.
A recent study found that shutting down a coal-fired power plant significantly improves fetal health in downwind areas. The analysis of birth outcomes showed a 15% reduction in low birth weight and a 28% decrease in preterm births in areas affected by the plant's emissions.
Researchers detected a high rate of thyroid cancer in young individuals from Fukushima Prefecture after the 2011 nuclear accident. However, no clear evidence suggests an increased incidence of thyroid carcinomas following the accident, contrasting with Chernobyl's findings.
Researchers in Colorado study 200 people affected by AFFF contamination, collecting data on biological markers and health indicators to assess biopersistence and potential health impacts of PFASs. The study aims to provide a better understanding of the effects of long-term exposure to these chemicals.
Researchers developed a mathematical model that simulates tumor growth and predicts response to cancer drugs. The model uses parameters of tumor growth to forecast treatment effectiveness, potentially leading to new strategies for predicting tumor response.
NIFA's investments support transformative discoveries in maximizing agricultural productivity, providing a safe food supply, and promoting responsible stewardship. The partnership aims to bolster the US economy by creating jobs and enhancing nutrition while sustaining natural resources.
Carnegie Mellon University's Tom Mitchell and MIT's Erik Brynjolfsson describe 21 criteria for evaluating task amenable to machine learning. Skills people develop and investments businesses make will determine who thrives in ML-driven economy.
Researchers from HSE and University of Valladolid created a neural network prediction model to detect corruption cases in Spanish regions. The model uses macroeconomic and political determinants to estimate the probability of corrupt cases emerging over three years, providing valuable insights for anti-corruption measures.
Entomologist Gia Aradottir from Rothamsted Research explores insect communication through chemical signals and sound-based interactions. Her experiments with aphids and parasitic wasps demonstrate the complex ways insects convey information to each other.
Researchers recreate ancient copper alloy colours using colour charts, shedding light on the importance of aesthetics in prehistoric metal-making. The study reveals that early tin bronzes may have had a distinctive golden hue, driven by demand for an 'exotic' colour.
New research by professors Sunil Mithas and Michael Kimbrough at the University of Maryland shows that IT investments also matter to bond markets. Bond investors favor IT investments in industries where automation and richer information flows are key, but view them as riskier in transform industries.
A 10-minute burst of exercise can measurably boost brain power, improving focus and problem-solving skills. Research found that exercising for a short duration primes the brain's problem-solving areas, leading to faster reaction times and improved cognitive performance.
A new DNA marker discovered by University College London researchers can detect fatal breast cancer up to a year before symptoms appear. The EFC#93 DNA methylation marker in blood serum correctly identified 43% of women who went on to be diagnosed with fatal breast cancer within three to six months.
A new study challenges the long-held assumption that soil animals contribute to the self-reinforcing effect of climate change by releasing more CO2. The research found that warming temperatures and drought actually lead to a decrease in feeding activity, contrary to expectations.
Researchers at Bar-Ilan University demonstrate that each neuron functions as a collection of excitable elements, where inputs from different directions are processed differently. This new understanding could impact research into the origin of degenerative diseases and challenges traditional spike sorting techniques.
A team of researchers identified a crucial region in Numb that binds and inhibits Mdm2, stabilizing p53 levels. This interaction is key to understanding the regulation of p53 in breast cancers, which tend to retain a functional p53 gene.
A team of researchers at Stanford University School of Medicine identified four on-the-market drugs that successfully quelled symptoms triggered by several overabundant proteins in patients with a rare eye disease. The findings demonstrate the potential of treating rare and complex eye conditions using precision health approaches.
A new methodology for correlating compound identity to CYP1A2 potency of inhibitors in metabolic mixtures has been developed, providing direct identification of compounds with inhibitory properties. This approach allows for rapid assessment of pharmacokinetic properties of drugs and their metabolites, improving drug development.
Researchers discovered that defects in monolayer molybdenum disulfide (MoS2) exhibit electrical switching, providing new insights into the material's electrical properties. This finding could contribute to MoS2's future use in opto-electronics and address current limitations.
Dr. Carmen Ulloa and her team compiled a comprehensive checklist of 124,993 vascular plant species of the Americas, representing one third of all known vascular plants worldwide. The checklist was published in Science today and used the Garden's plant database, Tropicos, as its data repository.
Weyl fermions, massless particles similar to light, were discovered in materials with strong electron interaction. They move extremely slowly despite no mass, lending unique properties to these materials.
A model predictive control framework incorporates adaptable interaction models for personalized human-robot collaboration, resulting in precise shared movements. Personalization allows robots to learn from users and adjust their interference to optimize performance.
Archaeologists have uncovered a vast, structured surveillance and communication network dating back to the Middle Bronze Age in northern Syria. The network, comprising fortresses, small forts, towers, and enclosures, stretched across approximately 7,000 km2 and was designed to protect urban areas and transport corridors.
Researchers developed a compact and inexpensive camera that produces high-resolution 3D images from a single 2D image. The DiffuserCam uses computational imaging to reconstruct 100 million voxels from a 1.3-megapixel image, with potential applications in brain research, self-driving cars, and machine learning.
A study by Instituto Gulbenkian de Ciencia found that worldwide peaks of sexual interest coincide with specific religious celebrations, leading to peaks in birth rates. Online searches related to sex display a cyclical nature that correlates with a specific "loving mood" independently detected on Twitter.
A new study from the University of Pennsylvania found that children who eat fish at least once a week have better sleep quality and higher IQ scores. The researchers discovered that increased omega-3 consumption is associated with improved cognitive function and reduced sleep disturbances.
The study presents a comprehensive checklist of 124,993 plant species across North and South America. Notably, the vast majority of plant species in the Americas are found in just one country or region, with Brazil having the most diverse flora. The authors predict an additional 25,000 species will be documented by 2050.
Researchers have developed small shining molecules that can recognize specific proteins in the brain, such as amyloid beta and tau. These molecules emit light at different wavelengths when bound to their target protein, enabling potential diagnostic tools for neurodegenerative diseases.
A new population-based model has been developed to track new HIV infections with greater accuracy, enabling researchers to better target prevention strategies and evaluate interventions. The tool uses biomarkers to identify recent infections, reducing false classifications and costs for studies.
Researchers discovered a mechanism to regulate switching between breast cancer-associated genes, using G-quadruplex structures. The study provides new insights into alternative splicing and could lead to the development of novel therapeutic strategies for controlling cancer growth.
The new book highlights scientific advances and emerging opportunities for targeted research, focusing on key questions to improve management effectiveness. World-renowned experts discuss the biology, ecology, and early life stages of COTS, emphasizing the need for improved knowledge to prevent outbreaks.
Researchers have gained crucial gene-level insights into an age-old evolutionary arms race between wheat and stem rust disease, a devastating fungal pathogen. The studies identified key peptides released by the fungus that can evade plant immune systems, potentially allowing for more effective DNA testing to identify resistant crops.
Research from the University of East Anglia found that singing in a community group improved mental health for participants. The combination of singing and socializing promoted feelings of belonging and well-being, leading to improved mood and daily functioning.
Researchers have isolated the first rust pathogen gene that wheat plants detect to 'switch on' resistance, allowing for faster DNA testing and prioritizing resistance genes. The breakthrough could save crops from being destroyed by devastating diseases, threatening food security globally.
Chemists at Ruhr-Universität Bochum tracked individual water molecules attaching to an organic molecule, exploring hydrophilicity and hydrophobicity. The study uses low-temperature scanning tunneling microscopy, providing insights into solvation processes.