Researchers at Duke University have developed a new optical sensing platform that can detect genomic cancer biomarkers in tissue samples using silver-plated gold nanostars. This technique has the potential to provide fast and reliable diagnostic results for cancer and other diseases, simplifying testing processes.
Researchers have demonstrated the potential of a leukemia drug, arsenic trioxide, to treat medulloblastoma, a type of brain cancer most common in children. The drug made tumor cells more sensitive to radiation therapy and proved capable of killing tumor cells and preventing new colony formation.
Researchers will test two existing drugs against SARS-CoV-2-infected mini lungs in a dish to find solutions for COVID-19. The grant aims to advance promising drug candidates and improve patient care.
Researchers at Tokyo University of Science discovered that transcription factor PU.1 plays a crucial role in regulating PD-L2 expression, which has implications for developing new treatments for immune-related disorders and cancer. The study sheds light on the molecular events underlying PD-L2 regulation.
Lionfish in Curacao reefs exhibit strong preference for brown chromis over other two prey fish species. The study suggests that lionfish can be picky about their daily menu as long as they are not starving, with poorer condition fish being less selective.
The researchers report two new cryo-EM structures representing the pre- and postfusion conformations of the full-length SARS-CoV-2 spike protein. The findings suggest that current vaccine strategies may be relying on limited information about the natural state of the protein, highlighting the need for further evaluation.
Researchers use VLA radio telescope to image galaxy NGC 4217's magnetic field, extending far beyond the galaxy's disk. The dynamo theory suggests that this massive magnetic field is generated by plasma motion within the galaxy's disk.
Researchers at Rockefeller University have created new surrogate viruses to test neutralizing antibody activity against SARS-CoV-2, enabling rapid testing in biosafety level 2 labs. The tools will help assess vaccine efficacy and develop antibody-based therapies.
A UCLA study reveals that COVID-19 antibodies decrease by roughly half every 36 days after infection in people with mild cases of the disease. This rapid decay raises concerns about the reliability of antibody tests and the potential impact on herd immunity and vaccine effectiveness.
Researchers at Ruhr-University Bochum used EEG to study the impact of repetitive tactile stimulation on brain activity. They found that neuronal responses adapted to the frequency of stimulation and showed changes over time, potentially illustrating a learning process.
Researchers from Skoltech and MSU discovered the type of electrochemical reaction associated with charge storage in the anode material for sodium-ion batteries. They also developed a method to produce hard carbon with high capacity comparable to graphite, a crucial step towards commercializing SIB.
Researchers at UCLA have identified a potential new combination therapy to treat advanced head and neck squamous cell carcinoma by targeting BMI1 proteins. The study found that using an anti-PD1 immunotherapy drug in combination with PTC209 successfully stopped cancer growth, prevented reoccurrences, and eliminated cancer stem cells.
A new study published in PLOS Medicine suggests that combining self-imposed prevention measures like handwashing and mask-wearing with government-imposed social distancing can delay and reduce the peak of a COVID-19 epidemic. The model found that if self-imposed measures exceed 50% efficacy, large epidemics can be prevented.
Researchers found that Fusobacterium nucleatum, a common mouth bacteria, can initiate cancer cell migration by sticking to and entering cancer cells using protein Fap2. This causes cancer cells to release cytokines IL-8 and CXCL1, leading to inflammation and attracting immune cells.
Researchers have created an optical switch that can direct high-frequency gamma radiation by switching the acoustic field. This effect demonstrates controlled transparency of a resonant medium for gamma radiation, which may be useful for controlling generated radiation in modern synchrotron sources and X-ray lasers.
A non-invasive blood test, PanSeer, can detect five common types of cancers four years before conventional diagnosis methods. The test detected cancer in 91% of asymptomatic samples and accurately identified cancer-free samples 95% of the time.
Researchers pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2), to distinguish between atopic dermatitis and psoriasis with 100% accuracy using adhesive tape strips. The study identifies distinct immune response markers for each disease.
Researchers propose a new method for constructing higher-order topological insulators using ring resonators and synthetic dimensions, enabling dynamic control over system parameters. This approach allows for the creation of high-dimensional topological insulators with exotic properties.
Researchers analyzed the magnetic field of Milky Way-like galaxy NGC 4217 and discovered unique structures such as X-shaped fields, helices, superbubbles, and giant loops. These findings suggest a connection between star formation and supernovae explosions in shaping the galaxy's magnetic field.
Researchers discover that alcohol activates microglia in the brain, altering geometry and increasing dopamine diffusion, which may promote addiction. This study provides a new understanding of alcohol's effects on the brain and suggests potential treatments.
A new study found that children with newly-diagnosed type 1 diabetes have a distinct gut microbiome composition associated with poorer blood sugar control. The researchers used machine learning analysis and genetic analysis to identify this link, highlighting the importance of gut health in disease development.
A new method detects MIR images using Si cameras through non-degenerate two-photon absorption, enabling simple and efficient imaging. The approach avoids alignment artifacts and utilizes the nonlinear optical properties of the Si chip itself to trigger photo-induced charge carriers.
Thanks to a decade-long collaboration, the global population of the critically endangered Chinese crested tern has more than doubled, from fewer than 50 adults to over 100. The project used social attraction techniques to lure adult seabirds to restoration sites with suitable nesting habitat.
Researchers at Stanford University have created a handheld, portable device to measure ammonia levels in blood. The device, which assesses ammonia levels from a finger or earlobe prick, can report results in less than a minute and is significantly more efficient than current methods.
Researchers studied convenience samples from 10 US geographic sites to estimate SARS-CoV-2 antibody prevalence. The study found varying levels of antibodies across different regions.
Researchers propose an all-optical method to modulate plasmonic response in graphene and metal-based systems using intense pump beams, enabling ultrafast light modulation. The technique exploits nanoscale photothermal effects to heat electrons, inducing changes in conductivity and optical properties.
A set of reviews concludes that hundreds of studies link widespread health issues including infertility, diabetes, and impaired brain development to hormone disruptors in pesticides, flame retardants, and certain plastics.
A new CSU study found that physical stress at work is linked to faster brain aging and poorer memory in older adults. Those who reported high levels of physical stress had smaller hippocampal volumes and performed poorly on memory tasks.
Researchers at the Weizmann Institute of Science created artificial cells that produced viral parts, allowing for safe testing and development of diagnostic tools, drugs, and vaccines. The system consists of micrometer-sized compartments etched into a silicon chip, enabling controlled production of specific proteins.
Researchers at Flinders University warn that family members can be the first to detect early signs of a problem gambler. Chronic hypervigilance, relationship conflict, and exhaustion are common consequences for partners and families.
A new study found that training doctors in anaesthetic skills using Lego bricks can improve their performance. The study used a simple task where participants copied shapes using bricks to see in a mirror, and found that this improved their ability to perform ultrasound-guided regional anaesthesia tasks.
A new study explores patients' views on hospital fundraising practices, finding that certain strategies cause concerns. Hospitals can show appreciation to donors through nicer hospital rooms, expedited appointments, or providing doctors' cell phone numbers, while avoiding wealth screening and sharing patient names without permission.
A new study by YANG Jia and colleagues identified both task-specific and subject-invariant components of perceptual learning ability, revealing multifaceted nature of learning and strong evidence for consistent pattern of individual differences across multiple training tasks.
A collaboration between Cornell and Northwestern universities has exposed tiny chemical flaws in human enamel using atomic imaging techniques. The findings suggest that irregularities in the enamel's structure may play a role in reinforcing it, making it more resilient to decay.
A recent study by Flinders University highlights the escalating gendered burdens faced by women during the pandemic, particularly in frontline healthcare roles and unpaid care work. Women experienced discrimination, eviction threats, and restricted access to essential services under COVID-19 restrictions.
Researchers at the University of Tsukuba found that epidermal stem cells undergo a change in their complex sugar repertoire with age, which could serve as a biological marker of aging. This 'glycome shift' is characterized by an increase in sialylated complex type N-glycans and a decrease in mannose-type N-glycans.
Researchers have developed a droplet biosensing method that can detect the presence of COVID-19 in a sample in just minutes. This fast and accurate method uses surface-enhanced Raman spectroscopy to analyze viral genetic material, reducing testing time and error margin.
Researchers found that over 20% of US homes lack sufficient space and plumbing facilities to isolate or quarantine COVID-19 patients. The study suggests that offering hotel stays with medical supervision at no cost could decrease transmission in minority communities.
Researchers found that the WA Christmas Tree, a parasitic plant, adapts to its environment by adjusting to temperature changes rather than relying on precipitation. This discovery has implications for conservation and restoration efforts, as it could inform the collection of seed for these species.
A study from the University of Tokyo found that feeding distillation remnants from shochu production to pigs reduces stress levels and improves the quality of meat, resulting in better-tasting sirloin and fillets. The leftovers also contain nutrients like leucine and histidine peptides, which may contribute to the benefits.
Researchers have demonstrated coherence times up to 10,000 times longer than previously recorded for spin-orbit qubits, making them an ideal candidate for scaling up silicon quantum computers. Strong spin-orbit coupling is key to achieving stable qubits and robust quantum information.
A new University of Michigan study estimates that wealthy American homes generate about 25% more greenhouse gases than lower-income residences, mainly due to their larger size. The researchers used data from over 93 million American homes to create nationwide rankings by state and zip code.
A new study from the University of California, Davis, shows that toddlers may experience and deal with uncertainty in decision making like older children and adults. Toddlers gather information before making decisions, taking extra time on difficult trials, and exhibiting behaviors that suggest they can respond to uncertain situations.
Researchers at Rice University have developed a new strategy, 'wrap, trap and zap,' to combat antibiotic-resistant bacteria in wastewater treatment plants. The graphene-wrapped nanospheres kill bacteria by producing reactive oxygen species, degrading antibiotic-resistant genes and minimizing their release into the environment.
A NIH study found consistent sex-based differences in cortical volume across 2,000 brain scans, which correspond with patterns of sex-chromosome gene expression. These findings suggest that genetic mechanisms, including those on the X and Y sex chromosomes, may influence sex differences in brain anatomy.
A new portable DNA detection method can identify tree pests and pathogens like the Asian gypsy moth and sudden oak death pathogen in under two hours. The device uses PCR testing to analyze tiny amounts of DNA and has been tested on multiple destructive invasive species.
A team of geophysicists used the ROMY ring laser to measure the Earth's rotational velocity and axis orientation, achieving the most precise ground-based measurements yet. The instrument detected minute alterations in the Earth's rotation caused by ocean currents, ice mass shifts, and seismic events.
Researchers found that certain species of foraminifera can survive and thrive in anoxic environments with high levels of toxic hydrogen sulfide. The organisms exploit soluble organic material as a source of carbon and energy, playing a crucial role in anaerobic nutrient cycles.
Researchers at Johns Hopkins Medicine have demonstrated that behavior therapy exposing people to memories of their trauma does not cause relapses of opioid or other drug use. Following the first therapy session, PTSD severity and emotional problems decrease significantly.
Researchers found that high genetic risk scores, including apolipoprotein E ε4, increase dementia risk by 2.6 times, while favorable cardiovascular health reduces the risk by 0.45 times.
A study finds that crop rotation effectively mitigates western corn rootworm damage to Bt cornfields, increasing yields and reducing fertilizer use. Farmers must diversify their Bt crops and rotate to prevent the pest's resistance.
Physicists at the University of Bath have accurately measured and characterised a single, twisted nanoparticle using a new method, taking them closer to producing medicines on demand. The discovery could lead to mini-labs that can mix substances in a completely new way, producing pharmaceuticals from minute droplets of active ingredients.
A UCSF study found that older adults with retained senses of hearing, vision, and touch have half the risk of developing dementia compared to those with marked sensory decline. The study tracked over 1,800 participants in their seventies for up to 10 years, revealing a stronger association between olfaction and lower dementia risk.
Researchers at the University of Maryland have discovered 37 recently active volcanic structures on Venus, suggesting the planet's interior is still churning. The study provides evidence that Venus is no longer a dormant planet and may hold clues to its geological development.
Researchers use cameras, drones, geolocators, and sensors to track wildlife and greenhouse gas emissions. Computing advances help analyze terabytes of data, enabling ecologists to scale up ecological research and address environmental challenges.
Research reveals exotic species diversity increases on Azores islands through human activities, disrupting native ecosystems and nutrient recycling processes. The study found a slight decrease in endemic island species, such as the Azorean money spider.
Researchers developed a system to monitor pneumonia and genetic diseases by analyzing breath exhaled by patients, revealing a new potential diagnostic tool. The technology uses specialized nanoparticles that release gases when proteases in the body cleave them, allowing for rapid detection of lung health.
Researchers develop Proteus, a lightweight material that turns back the force of cutting tools upon itself, making it resistant to angle grinders, drills, and high-pressure water jets. The unique structure of ceramic spheres encased in cellular aluminium creates an interlocking, vibrational connection that repulses any attack.
Researchers have successfully developed a method to 'upconvert' low energy light into visible light using oxygen, enabling it to be captured by solar cells. This breakthrough has the potential to increase the efficiency of solar cells and expand their sensitivity range.
International trade can compensate for regional food shortages and reduce hunger due to climate change. Eliminating protectionist measures and barriers to trade can relieve these differences.