A natural compound derived from gut-friendly bacteria significantly slows vitiligo progression and may restore pigmentation in mice. The findings could offer hope to millions affected by the autoimmune disease, which causes visible patches of skin discoloration and carries profound emotional and physical consequences.
Researchers at Rice University's Synthesis X Center and MD Anderson Cancer Center are developing a light-induced brain delivery platform to improve drug delivery across the blood-brain barrier for treating brain metastasis. The goal is to enhance survival rates and transform the standard of care for this deadly form of cancer.
Researchers at Penn State developed a strategic framework to optimize CSR activities, finding that directly related initiatives create both social and business value. The four-component framework focuses on shared value, enlightened stakeholder theory, resource-based theory, and CSR-fit perspective.
A study of men with a family history of prostate cancer discovered an inherited form of prostate cancer linked to the mutated gene WNT9B. This gene variant increases prostate cancer risk by two- to 12-fold, comparable to breast cancer risk conferred by pathogenic mutations.
Smallholder farmers in Western Kenya support native-tree restoration for improved crop yields, climate resilience, and food security. However, concerns about increasing tree diversity attracting wildlife and the need for locally designed solutions remain.
A new study published in Neuro-Oncology found that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously thought. The study suggests that doctors may need to rethink current screening guidelines for detecting brain metastasis in patients without symptoms.
A new study has identified specific gut cell types that communicate with T cells to tolerate or attack food, revealing how the intestinal immune system maintains balance. The findings also suggest that parasitic infections can disrupt tolerance mechanisms, leading to reduced food tolerance and increased allergy risk.
The journal examines dementia-related trends in high- and middle-income countries, highlighting the need for effective interventions to prevent dementia. Worldwide, dementia cases are expected to rise from 55.2 million in 2019 to 139 million by 2050.
The University of Bath's new Institute for Digital Security and Behavior aims to put people at the heart of research into digital security and behavior. Researchers will study factors that make individuals, organizations, and societies safer and more secure.
The ISS National Lab sponsored over 100 payloads to the orbiting laboratory, achieving the second-highest annual total. The lab also published a record 51 peer-reviewed articles in FY24, advancing scientific discovery and innovation.
The University of Texas at Austin's McCombs School of Business has established the Keith C. Brown Endowed Scholarship to support high-potential students from low- and middle-income families. The scholarship is made possible by a generous donation from Danielle DiMartino Booth, MBA '96, and her husband John.
Researchers developed MUNIS, a deep learning tool that predicts CD8+ T cell epitopes with high accuracy, potentially accelerating vaccine development. The tool was validated using experimental data from influenza, HIV, and EBV, demonstrating its potential to streamline vaccine design.
A study by Brown University researchers found that nearly half of primary care providers in the US are affiliated with hospitals or private equity firms, resulting in higher charges. These affiliations were linked to a 10.7% increase in negotiated prices for office visits compared to independent practices.
The fellowship aims to develop clinical expertise, leadership skills, and effective systems of care for treating substance use disorders. Dr. Sarah Kler will receive comprehensive training in delivering high-quality addiction care, joining a highly competitive program with a focus on reducing stigma.
Researchers at Harvard University used photochemical modeling to simulate how ancient Mars' climate was affected by atmospheric chemistry and crustal hydration. They found that episodic warm spells were driven by crustal hydration, leading to the buildup of hydrogen in the atmosphere.
Researchers successfully created a bi-paternal mouse by modifying genes involved in reproduction. The mice that reached adulthood exhibited altered growth and shortened lifespan, but could potentially lead to new therapeutic strategies for imprinting-related diseases.
The book provides a comprehensive, step-by-step overview of the Pyramid Model Practices for infants and toddlers from birth to 3 years old. It offers research-based practices to support early social-emotional development and language development in young children.
Researchers identified a deficit in contrast perception among people with schizophrenia, which affects identifying shapes, textures, and details. Further studies are needed to confirm this relationship and explore the role of medication and other factors.
A study of young adults found that heavy lifetime cannabis use is associated with negative outcomes on working memory tasks. These findings suggest potential long-lasting effects of cannabis use on brain function.
A recent study published in JAMA Network Open found that heavy cannabis users exhibited reduced brain activity during working memory tasks, associated with worse performance. Abstaining from cannabis before cognitive tasks may help improve performance.
A new AI-powered tool from KAUST researchers is mapping cause-and-effect relationships between diseases, creating a framework for targeted therapeutic strategies and disease prevention. The tool reveals surprising links between metabolic diseases and other conditions, including cardiovascular and nervous system diseases.
A new survey finds that nearly three-quarters of US adults support requiring children to be vaccinated against preventable diseases, while over half support prohibiting unvaccinated children from attending school. However, support for this prohibition has dropped significantly since the Covid-19 pandemic, and there is growing support f...
A team of researchers proposes a new generation of language models inspired by human language acquisition. They demonstrate how artificial agents learn linguistic constructions linked to their environment and sensory perceptions, leading to more realistic language understanding.
Researchers at Terasaki Institute develop lipopeptide hydrogels to deliver peptide-based cancer vaccines, demonstrating sustained release and enhanced immune cell uptake. The system shows promise in overcoming limitations of traditional peptide-based vaccines.
A high-resolution map and hierarchical classification system of Antarctica's ice-free lands reveal nine Major Environment Units, 33 Habitat Complexes, and 269 Bioregional Ecosystem Types. This unprecedented level of detail provides a critical foundation for protecting biodiversity in the continent's fragile ecosystems.
Researchers found no increase in large iceberg sizes over the last half century, contradicting climate change expectations. Instead, frequent small calving events have dominated ice shelf loss, suggesting 'death by a thousand cuts',
Schuman and her team aim to create a large library of open-source code, tools, and training programs for neuromorphic computing. They will provide community-level access to NMC systems, enabling widespread use and research in various scientific fields.
A new study found that driving-related conversational prompts improve driver performance in taking control of the vehicle, but only when drivers are engaged. Conversely, non-driving related tasks like solving anagrams can significantly decrease performance and render prompts ineffective.
A recent study reveals that rats' visual recognition abilities are extremely efficient and adaptable, even outperforming advances in artificial intelligence. Rats employ more flexible image processing strategies than CNNs, which could inspire new approaches to AI model development.
A study by Kyushu University economists found a significant economic impact on Japan's tourism industry, resulting in a loss of 3.44 trillion yen and 22 billion US dollars. The pandemic also led to employment declines for 868,976 people, with the highest losses in restaurants and hotels.
Two new European projects, GuardIAS and OneSTOP, aim to tackle the threat of invasive alien species on endangered species, natural sites, and human health. The projects will use advanced scientific research, cutting-edge technology, and artificial intelligence to develop new tools for detection, prevention, and eradication.
A study found that pregnant patients with chronic hypertension and gestational hypertension are at a higher risk of severe maternal morbidity compared to those with normal blood pressure. The researchers suggest preventing preeclampsia in these patients may reduce this risk, making them comparable to normotensive patients.
Researchers have discovered persistent and large magma bodies beneath dormant volcanoes in the Cascade Range, surprising scientists. The team used seismic waves to identify these magma chambers, which exist beneath volcanoes over their entire lifetime, not just during active eruptions.
A team led by biologist Thomas Mayer found that a small binding-pocket on cyclin B helps regulate the sequence of cell division events. Without this pocket, malformations occur due to incorrect kinase phosphorylation, leading to potential tumours or infertility.
A new video game, CAMI, uses motion-tracking technology to detect differences in motor imitation skills, distinguishing children with autism from neurotypical children and ADHD patients with 80% accuracy. The tool has the potential to transform autism diagnoses worldwide by providing a quick, low-cost, and easy-to-use alternative.
PolitiFi, a new form of meme coin cryptocurrency inspired by internet culture and humour, was explicitly affiliated with political candidates in the 2024 US elections. The coins helped shape narratives, enhance visibility, and boost political engagement among voters in the cryptosphere.
A cohort study from JAMA Network Open reveals an association between temperature exposure and increased psychiatric symptoms among adolescents in the Netherlands and Spain. The findings suggest a possible link between climate change and mental health, warranting further research across diverse climates.
Researchers found that the mites sense and rely on electric fields generated by hummingbird wings for survival. The study revealed that the mites are attracted to specific frequencies of static electricity and can recognize positive charges.
Tobias Ackels' research reveals that mammals can differentiate between odor sources at lightning speed, using a temporal dimension to orient themselves in space. This ability is encoded in the output of the olfactory bulb and could be used for early detection of dementia.
The foundation has awarded eight recipients of the 2025 Damon Runyon-Rachleff Innovation Award, including five early-career researchers with initial grants of $400,000 over two years. The awardees aim to develop novel cancer therapies using innovative approaches such as engineered skin bacteria and small molecule-boosted drug delivery.
Researchers from the University of Turku and Natural Resources Institute Finland found that combining accommodation and repelling fields can help mitigate crop damage and human-wildlife conflict. The study suggests using stakeholder knowledge and coordinated field design to prepare for goose damage and reduce costs.
Southwest Research Institute's Risk Evaluation & Medical Decision Efficacy (REMEDY) tool supports agile medical decisions on countermeasures for chemical and biological threats. The REMEDY mission risk evaluations quantify risks and benefits of medical countermeasures, enabling operational planners to make informed decisions.
The European Society for Paediatric Endocrinology and the European Society of Endocrinology will host the first-ever joint Congress on May 10-13, 2025. The event aims to bring together paediatric and adult endocrine specialists from across Europe and the world to collaborate and celebrate endocrinology.
The new center aims to translate discoveries into better diagnostics and treatments, benefiting patients worldwide. HonorHealth's research institute is investing in cutting-edge clinical trials and collaborations to develop novel therapies.
Aging cats with chronic kidney disease (CKD) have lower levels of key kidney transporter genes, leading to impaired waste removal. Monitoring these transporters and toxin buildup may help detect CKD early and improve treatment options.
Researchers at the University of Pittsburgh have developed a new way to grow T cells that can live longer and better destroy cancer cells in mice. By adding a compound called dichloroacetate to growth media, they created T cells less reliant on glucose and more efficient at using other energy sources.
Researchers developed two low-resource sessions to improve PCC staff wellbeing, focusing on social support, self-belief, and feedback. Feedback from staff was positive, with high satisfaction and feasibility ratings.
A new study reveals striking similarities and critical gaps in how three major countries measure healthcare quality, with an emphasis on family medicine and process-focused metrics. The findings underscore the need for a more balanced approach that includes all aspects of medical care, from infrastructure to patient outcomes.
Researchers from ANEMEL have developed highly stable anion exchange membrane electrolysers that can produce hydrogen without using platinum-group catalysts. The new technology surpasses state-of-the-art solutions in performance and long-term stability, holding promise for industrial applications.
Researchers at Leipzig University developed a new standardised numberinng system for adhesion G-protein coupled receptors (GPCRs) to improve comparability and analysis. The system is based on AI analysis of over 14,000 modelled structures and facilitates deeper insights into disease-relevant mutations in GAIN domains.
A deadly ciliate parasite has decimated sea urchin populations in the Caribbean, Red Sea, and Indian Ocean, with mortality rates reaching over 90%. The International team of researchers is working to track the disease and preserve sea urchins, which play a crucial role in maintaining coral reef health.
A new study found that empathy responses peak in young adulthood, with increased sensitivity to social pain. This development demonstrates that empathy strengthens as people age, but also accompanies reduced ratings of pain for others, highlighting the complexities of empathic responses.
Researchers at Istituto Italiano di Tecnologia and Imperial College London demonstrate the connection between hand movement patterns and motoneuron control patterns, enabling natural control of bionic limbs. The study reports successful testing of a soft prosthetic hand with individuals with physical impairments.
Researchers found that fewer veterans reported having access to firearms than expected, with only 5% included in discussions. The study also revealed that most veterans with opioid access did not accept overdose-reversing medication, highlighting the need for improved suicide safety planning.
A novel lab-on-chip platform uses acoustofluidics to efficiently separate rare circulating tumor cells, enabling real-time diagnosis. The system's precision and energy efficiency hold promise for improved cancer diagnostics and personalized medicine.
A KAUST-led research team discovered EZH1 plays a dual role in circadian regulation, stabilizing RNA Polymerase II and reshaping chromatin to activate or silence genes on schedule. This ensures genes involved in metabolism, sleep, and other essential processes rise and fall on cue.
Researchers identified a potential new treatment for aggressive sarcoma arising in nerves, using a pre-clinical platform that combines inhibitors targeting specific mutations. The triple combination of MEKi-BETi-CDKi showed promising results in shrinking tumors and even eliminating some cases, offering hope for improved treatment options.
A new study found that oxytocin treatment can improve apathy symptoms in patients with frontotemporal dementia. The trial, conducted across 11 sites in Canada and the US, showed a significant improvement in apathy levels when patients received oxytocin compared to placebo.
Researchers have developed a perovskite X-ray detector that uses cascade engineering to reduce dark current, enabling high-quality medical images at ultra-low doses. The device achieved a detection limit of 100 nGy·s−1, a significant improvement over previous limits.
Rising temperatures alter lignin deposition in plant cell walls, requiring adaptive strategies for a resilient supply chain. Understanding regional variations, exploring alternative sources, and developing climate-resilient plant varieties are crucial to mitigate the effects of global warming.