A new combination therapy called QUIZOM significantly improves treatment outcomes and survival in patients with FLT3 gene mutations. The study found a composite complete remission rate of about 83% while reducing the risk of relapse, providing an effective and feasible treatment option for high-risk blood cancers.
A new strategy enhances oxygen reduction in zinc-air batteries by fine-tuning an efficient catalyst. The Fe2O3/Sm2O3 heterointerface accelerates ORR kinetics by inducing charge redistribution and orbital hybridization.
Researchers at UTMB have developed a single-dose vaccine against the Andes hantavirus that provides full protection in animal testing. The vaccine's powerful immune response creates protective antibodies in as little as 14 days, making it a potential emergency tool for high-risk contacts during outbreaks.
Researchers at HKU have discovered a significant piezoelectric effect in ultrathin and ultra-flexible polycrystalline diamond membranes. The finding challenges the long-held assumption that diamonds are non-piezoelectric, opening up new possibilities for medical and energy applications.
The JUNO Collaboration has made the high-precision measurement of two key oscillation parameters, reducing associated uncertainties by a factor of 1.6 compared to past decades. This result validates detector performance and analysis methodology, establishing JUNO as a key player in precision neutrino oscillation physics.
A clinical trial found that low-dose atropine eye drops are safe and effective in reducing myopia progression in UK children. The treatment led to a small decrease in refractive error and eye growth compared to placebo.
Scientists mapped the genetic history of ancient grapevines from Tuscany's Cetamura del Chianti settlement, discovering a single, identical variety passed down for centuries. The study found that white grapes were dominant in ancient Chianti, contradicting the region's modern reputation for red wines.
A study published in The Lancet found that Chile's comprehensive food policies, including labelling and advertising bans, have a real-world impact on reducing child obesity. After implementing the Food Labelling and Advertising Law in 2016, children who had been at school for 18 months showed a lower risk of overweight or obesity compa...
Research reveals that zebra finch chicks' brain development is altered by heat warning calls in the egg, preparing them for hot conditions after hatching. The changes involve genes involved in blood vessel structure and muscle contraction, potentially protecting the chicks from heat stroke.
Researchers at Sanford Burnham Prebys Medical Discovery Institute found that enhancing protein-folding processes can help prevent harm to insulin-producing cells. The study revealed the importance of a chaperone protein called binding immunoglobulin protein and its cochaperone protein p58 IPK in maintaining proper proinsulin folding.
A new study published in Science challenges the myth of simple Barbarian domination in the Early Middle Ages. Researchers found that communities in northwestern Hungary formed part of a dense network, with populations showing southern European genetic ancestry and Asian/African diversity.
A new study reveals that biochar can regulate antibiotic movement in structured soils, helping reduce contamination risks. By shifting transport into the slower soil matrix, biochar reduces pollutant export and increases retention.
A new study found associations between cardiac remodeling and higher risks of breast and colorectal cancers, with left ventricular mass index linked to breast cancer risk and reduced peak left atrial strain predictive of colorectal cancer risk. The study suggests that early heart changes may serve as an early marker for identifying ind...
A new review highlights the potential of biochar's intrinsic redox properties to enhance pollutant degradation, microbial processes, and energy recovery. Biochar can act like an electron shuttle or buffer, transferring electrons more efficiently than highly conductive materials in stressed environments.
A new study found that soil fungi play a key role in supporting carbon retention and improving fertility in nutrient-poor urban soils. Biochar and compost increased soil carbon and nitrogen storage most strongly in these soils, with amendment effects up to 14.4 times greater than those observed in nutrient-rich soils.
The Society of Nuclear Medicine and Molecular Imaging (SNMMI) has announced the recipients of five Drs. Jane & Abass Alavi Mars Shot Research Awards, supporting studies on inflammatory bowel disease, artery inflammation, and other conditions.
Researchers at MIT found that people expect generosity to flow one way in asymmetric relationships, and follow precedent to maintain equal relationships. In symmetric relationships, such as friendships or family ties, reciprocity is expected, but not in asymmetric ones.
The Luxembourg AI Factory released an open-source tool to accelerate testing for trustworthy artificial intelligence. The AI Assessment Sandbox Configurator enables rigorous AI testing at scale, addressing regulatory requirements and ensuring trustworthiness.
A new study forecasts global antimicrobial resistance threats for the next two decades, identifying 210 traits that could pose the greatest future risk. The research uses machine learning and forecasting to predict which genetic factors will become more prevalent and which may decline over time.
The study found that increasing light intensity decreases diffusion rates of nanotubes in water, a phenomenon known as light-induced quantum friction. The team also demonstrated the immediate coupling between nanotubes and water using terahertz spectroscopy.
Johanna Joyce, a leading tumor immunologist, has begun her two-year term as President of the European Association for Cancer Research. She will focus on strategic oversight, promoting broad scientific collaboration, dialogue, and training, while addressing issues such as gender disparities in science.
A new study found that third-graders with higher impulsive behavior had lower math and reading scores in elementary and high school, as well as fewer years of education as adults. Children who could 'keep it together' for longer tended to do better academically.
FemTech has expanded over the past decade to become a major force for women's health worldwide, tackling issues like reproductive health, cardiovascular disease, and chronic conditions. International funding bodies are creating opportunities for innovation, enabling researchers to redefine how women access and experience medical care.
A team of physicists used mathematical modeling to describe the spread of opinion and election results in terms of anomalous diffusion. Their research found that certain social phenomena exhibit similar characteristics to physical systems, such as particle movement in complex media.
Researchers at UCLA Jonsson Comprehensive Cancer Center have been awarded a $3.2 million NIH grant to develop advanced imaging and surgical strategies for improving glioblastoma outcomes. The team aims to use pH-based imaging to guide precise tumor removal and explore targeted therapies that target the tumor's acid-regulating systems.
A new study reveals that despite a decline in national lead levels, children of color and from low-wealth families continue to face higher exposure risks due to increased lead in old homes and cultural products. The authors call for policy solutions to eliminate all sources of lead and provide targeted interventions to reduce disparities.
Researchers are developing novel yeast strains and fermentation methods to reduce alcohol in wines while maintaining flavor. The goal is to achieve meaningful reductions in alcohol content, which can impact balance, consumer appeal, and tax classifications.
A new University of Michigan study found that nursing job turnover increased significantly since the pandemic, with over 24% of registered nurses leaving their primary positions. The main reasons for this increase were stressful work environments, burnout, and inadequate staffing, which affected all care settings.
Researchers developed a liquid material that charges like a battery, transforms like a living organism, and resets itself in open air. The material stores power for months and can be recharged, making it useful for adaptive clean renewable systems.
Two new UH CPRIT grants will accelerate lung cancer prevention, diagnosis, and treatment. Researchers aim to develop new mRNA-based immunotherapies and a next-generation blood test for precise lung cancer detection.
Researchers identify hormone-driven molecular cascade enhancing K⁺ uptake in cotton under low-K⁺ conditions, revealing synergy between jasmonic acid and ethylene pathways. Foliar application of MeJA or ACC improves leaf K⁺ concentration and photosynthetic performance, increasing seed cotton yield by 11.6%.
The American College of Cardiology has selected 47 clinicians to participate in its inaugural Fuster Prevention Forum, which focuses on early cardiovascular disease prevention. Participants will gain skills to enact change and foster a culture of prevention in their communities.
Researchers found that fructose communicates with the brain through a different gut-brain pathway, leading to less effective hunger suppression compared to glucose. This study challenges the idea that hunger-related neurons track calorie intake regardless of nutrient source.
A new national analysis found that mesothelioma deaths and diagnoses continue to rise in the US, with little improvement in survival rates. The disease disproportionately affects women and several high-risk states tied to shipbuilding, mining, and legacy asbestos exposure.
The Applied Microbiology International (AMI) 2026 Member Survey reveals a highly engaged membership community with strong satisfaction rates. Members highlight the need for clearer pathways for involvement, mentorship, and professional development to strengthen long-term engagement and retention.
A major study found that patients who measured and recorded their blood pressure at home had a significantly lower risk of hospitalization and death from cardiovascular diseases. The use of digital telemonitoring systems can help improve health outcomes, save lives, and ease pressure on the NHS.
The study demonstrates how environmentally responsible strategies can be integrated into chemistry classes while maintaining academic rigor. Students at Georgia State University conducted a redesigned experiment as part of their coursework, experiencing green chemistry concepts directly in the lab.
A Yale-led study analyzes genetic variation in Oceania populations, uncovering insights into human evolutionary history and adaptation. The research found that ancient DNA from Denisovans continues to shape human biology today, influencing gene expression and immune function.
Research reveals that leaving deadwood in forests and creating artificial gaps can increase the diversity of bats and birds, with some species responding strongly to these changes. The study found that forest interventions can promote biodiversity even in previously monotonous ecosystems.
The Gerontological Society of America has renewed funding for the Journalists in Aging Fellows Program, which has produced over 900 news stories since its inception in 2010. The program aims to educate journalists about aging issues and disseminate information on scientific findings, policy debates, and innovations.
A new study finds that approximately 15% of current global warming is attributed to 'indirect greenhouse gases,' including carbon monoxide and nitrogen oxides. The authors call for integrating these gases into climate policy frameworks, emphasizing their significant impact on warming.
Physicists at UC Berkeley introduce phase contrast to electron microscopy, enabling clearer images of small molecules and structures inside cells. The laser phase plate enhances cryoelectron microscopy, overcoming signal-to-noise limitations and paving the way for new drug discovery.
The Science journal has issued an Editorial Expression of Concern regarding a 2024 Research Article on using dialogues with AI to reduce conspiracy beliefs. The authors reported inconsistencies in their analysis pipeline and dataset, which affected the reproducibility of their results.
Researchers have developed a digital brain twin using multimodal data, providing anatomically accurate brain models that can be used in experimental and clinical settings. The models were reconstructed simultaneously with brain anatomy and dynamics from neural data.
Researchers have identified a new mechanism behind the Venus flytrap's snap action: a one-second softening of its outer epidermal cell walls. This dynamic tuning of material properties could inspire bio-inspired movement in soft robotics and smart materials.
A new study found that socioeconomic factors, including increased stress and reduced sleep, are strongly associated with changes in brain structure and function in children. The research suggests that early support for families is needed to address these effects.
A proposed fairness framework aims to address bias and inconsistency in faculty promotion and tenure decisions, ensuring meritorious candidates are recognized regardless of background. The framework, called SET, identifies targeted changes to existing processes to reduce bias and increase equity.
Researchers found that socioeconomic factors, such as family income and neighborhood resources, have a strong connection to brain development in children. These factors are more strongly linked to brain function than IQ scores or parenting style, and can even affect the structure of the brain through disrupted sleep and chronic stress.
Researchers find that low-severity fires, such as prescribed burns, can significantly reduce the probability of very high severity wildfires for a decade. This reduction in smoke particulate pollution leads to cumulative benefits of up to 10% over a decade.
A Stanford-led study suggests that burning 500,000 acres of California conifer forests each year with prescribed fire could cut deadly pollution from wildfire smoke by roughly 10% over a decade. The risk of very severe fires immediately drops 92% in areas burned in low-severity fires, with risks remaining lower for up to a decade and e...
Researchers at Biohub and UC Berkeley have developed a laser phase plate that dramatically improves contrast in cryo-electron microscopy images, allowing scientists to see small molecules and interactions within human cells. The device uses a laser 100 million times brighter than the Sun and is expected to revolutionize structural cell...
Researchers created the first global maps of arbuscular mycorrhizal fungi's distribution and mass, estimating ~110 quadrillion kilometers of network length and ~300 megatons of carbon. The networks support plant life and regulate climate by drawing in CO2 from atmosphere.
Researchers at Kyoto University developed a new organic molecule with an ultranarrow emission spectrum, achieving monochromatic light without strong excitation. The breakthrough opens up possibilities for OLEDs with extremely high color purity and advanced functionality.
VeriXiv's trust marker badges showcase rigorous verification checks, setting new standards for preprint integrity. The badges provide clear confirmation of the extensive checks each preprint undergoes before being made available on the site.
Eighty medical students from across the US and Puerto Rico are selected for a six-week summer experience to introduce them to clinical research early in their careers. The program aims to develop the next generation of clinical investigators equipped to engage communities and improve participation in clinical trials.
A team of researchers has discovered large droplets of proteins known as condensates near inactive chromosome regions within the cell nucleus that are a feature of some cancer cells. The newly found condensates store excess gene-activating protein TEAD1, regulating its activity and preventing toxicity to the cell.
The collaboration aims to expand research and clinical program development in spinal cord stimulation, pairing it with intensive activity-based training to improve movement, mobility, and other functions. This effort will help move evidence-based practices into broader clinical use, benefiting people living with a spinal cord injury.
Researchers identified age-related genetic changes in microglia that may drive inflammation and neurodegeneration in Alzheimer's disease. Cancer-associated mutations were found in genes commonly linked to clonal hematopoiesis, promoting inflammatory activity.
Baylor College of Medicine researcher Dr. Jimmy Holder and his team will join the ARIA IMPACT Network to accelerate clinical trial readiness and implementation for promising therapies on autism. The collaboration aims to better understand how autism develops and changes over time in children with profound autism.
This Brazilian adult study explores the association between mental health, dermatology-related quality of life, and probiotic intake. Women were found to have higher anxiety, depression, and stress levels than men, with strong positive correlations among these conditions.