Seven original research studies on cardiometabolic therapies, structural heart disease, peripheral intervention, and shock care are published simultaneously by JSCAI at SCAI 2026. These findings highlight the intersection of cardiometabolic management and structural heart care, with implications for patient outcomes.
A new UC Santa Cruz study reveals that California's endemic and near-endemic trees are projected to lose between half and three-quarters of their climatically suitable habitat over the next century. The research demonstrates that current conservation status on the IUCN Red List do not reflect this imminent risk.
Researchers developed a controllable interfacial redox strategy using graphene to tailor surface chemistry of nickel-based metals, enhancing electrocatalytic oxygen evolution. The modified electrode exhibited improved OER metrics, including lower overpotential and smaller Tafel slope.
A Mount Sinai study reveals that early-life exposure to common environmental metals may shape brain development and behavioral health more than a decade later. The research combined baby teeth with advanced brain imaging, pinpointing specific weeks during pregnancy and infancy when the developing brain appears most vulnerable.
GFAKaleidos offers a unified framework for analyzing directed, bidirected, and biedged graphs, enabling in-depth examination of vertices, edges, and subgraphs. The tool provides intuitive visualizations and flexible deployment options, making it accessible to both beginners and experts in the genomics research community.
The review maps the most promising routes for recycling spent LiFePO4 batteries, focusing on pretreatment, impurity control, direct regeneration, hydrometallurgy, and selective auxiliary processes. It highlights hydrometallurgy as a promising strategy for large-scale recovery needs.
A survey on NeRF and 3DGS-based 3D editing provides a systematic review of latest techniques, outlining key advancements, challenges, and future research directions. These radiance field-based methods offer high-fidelity solutions for 3D scene representation and editing.
A new method called ProbsCut improves adversarial robustness by balancing accuracy and robustness through a variance-bias decomposition of generalization error. The proposed approach combines local loss with global loss, aligning the probability vectors of legitimate examples and their adversarial counterparts.
Scientists have developed an advanced microscopy technique to visualize critical components of the cell's transcription machinery and proteins that provide structural support to the nucleus. The new technique allows for the visualization of up to 12 biomolecules simultaneously, providing detailed maps of nuclear organization.
A new research method leverages auxiliary tasks and pose disentanglement to improve body height and weight estimation from a single non-frontal face image. The proposed method utilizes gender and age estimation as auxiliary tasks to enhance primary task performance, demonstrating superior results on small- and large-pose datasets.
Insilico Medicine nominates UAE's first developmental preclinical candidate using generative AI, marking a significant step forward for pharmaceutical innovation. The milestone showcases the country's growing biotechnological capabilities and its rise as a global hub.
Researchers developed DSPE to conceal ciphertext relationships, enabling dynamic deletion and maintaining semantic security. The framework offers a robust solution for next-generation privacy-preserving cloud services with high efficiency and practical computational overhead.
Researchers discovered high concentrations of tire- and rubber-related chemicals in Lake Sihwa sediments, with patterns reflecting changes in industrial activity and pollution control measures. The study provides a baseline for sediment concentrations, enabling understanding of future trends and potential risks to aquatic organisms.
A research team at the University of Cologne discovered that the protein cFLIP can be used to override the defences of Diffuse Large B Cell Lymphoma (DLBCL) against programmed cell death. Targeting cFLIP could re-activate cell death in lymphoma cells and provide a new therapy option.
Researchers discovered that sea urchin eggs can integrate chromoplast-derived carotenoid crystals, which enhance larval development and increase their survival rate by 50%. This integration enables the larvae to adapt to different environments.
Researchers developed a molecular engineering strategy to enhance PEMFC performance by tailoring the ionomer microenvironment. The addition of fullerenol improved oxygen transport and reduced platinum-sulfonate interactions, leading to increased peak power density and operational stability.
SST deformity, characterized by droopy glans penis, leads to cosmetic and painful issues, with conservative approaches offering benefits in mild cases. Durable correction through glanulopexy techniques achieves success rates of 85-95% with low morbidity, according to current management strategies.
Tiny bubbles in water electrolysis can account for significant efficiency losses, ranging from 5-25% of total energy input. Researchers are exploring ways to design electrode surfaces and optimize operating conditions to manage bubble buildup and improve performance.
Researchers find crab shell waste alters microbial communities on biodegradable plastics, reducing breakdown rate. The effect persists even without direct contact, suggesting biochemical compounds released from crab shells trigger changes in the plastisphere.
A study found that individuals with a high risk of type 2 diabetes do not benefit equally from lifestyle interventions, even after significant weight loss. Rising blood glucose levels and declining insulin secretion were observed in those who failed to show improvements.
A new detector technology has been developed to track elementary particles in large volumes of unsegmented scintillator material. The system uses a plenoptic camera and single-photon avalanche diode array sensors to achieve high-resolution 3D tracking, even in photon-starved conditions.
Researchers have discovered that optimizing sandbox execution time can significantly enhance the completeness and quality of cyber threat intelligence data. By analyzing over 110,000 malware samples, they found that 90% of useful intelligence is extracted within the first three minutes of execution.
A multi-center retrospective cohort study examined how cangrelor is used in real-world clinical practice around the time of surgery following PCI. The study found that varying dosing patterns can affect outcomes, with higher infusion rates associated with increased bleeding events and lower infusion rates linked to higher major adverse...
A research team has proposed powerful related-key boomerang attacks on two larger variants of HALFLOOP, highlighting urgent concerns about the design of cryptographic standards. The attacks significantly improve time complexity and achieve breakthroughs in key recovery, underscoring the need for stronger key schedule algorithms.
Dr. Dennis Slamon, a renowned breast cancer researcher, has been elected to the Association of American Physicians (AAP) for his pioneering work in HER2 gene discovery and targeted therapies. His research led to significant improvements in survival rates and established the principle of targeted cancer treatment.
Max Planck researchers have discovered how microscopic dendrites induce fractures in solid-state batteries, leading to short circuits. By understanding the counterintuitive phenomenon of dendrite formation, they've identified potential strategies to prevent or delay cracking.
Researchers found that cinnamic acid effectively inhibits plasmid-mediated conjugation, reducing the global spread of antibiotic resistance genes. The study suggests CA as a broad-spectrum conjugation inhibitor targeting bacterial energy metabolism to limit ARG spread.
A research team presents a general approach to batch verification of arbitrary signatures on blockchain, leveraging IVC to enhance scalability and reduce memory consumption. The proposed scheme supports an arbitrary number of signature verifications and offers significant speedups for both provers and verifiers.
A recent study explores how response timing affects people's use and evaluation of AI systems, challenging the assumption that faster is always better. Participants rated slower responses as more thoughtful and useful, highlighting a subtle but powerful feature of human psychology.
A computational protocol has been established by University of Kent researchers to accurately identify reactions that can result in successful drug candidates for Chagas disease. This approach reduces the need for trial-and-error, prioritizing promising compounds earlier and making the drug discovery process faster and more affordable.
Researchers used LP-TEM to visualize the dynamic processes occurring during early stages of liquid-liquid phase separation (LLPS) in intrinsically disordered proteins/regions. The study provides compelling evidence supporting a non-classical nucleation mechanism and proposes a multi-step process for LLPS, which is common in IDPs/IDRs.
A new framework, Synthegy, combines established search algorithms with artificial intelligence capable of interpreting chemical strategies expressed in natural language. This allows chemists to express their goals in plain language and receive strategically relevant solutions.
Hodgkin lymphoma cells are immune cells stuck in an 'identity crisis,' unable to mature into functional plasma cells. The team discovered that these cells downregulate key B cell features and upregulate proteins to make them more like plasma cells, but not completely functioning as such.
A research team at HHU Düsseldorf has discovered how the transport protein Rrm4 acts as a precision logistics expert in the fungus Ustilago maydis. The protein uses specific 'zip codes' on mRNA to identify and bind to, ensuring stable transport to distant sites within the cell.
The Yōni.Fit device is FDA-cleared for temporary management of stress urinary incontinence and also collects menstrual fluid and/or vaginal discharge. Clinical trials show a 96% clinically significant reduction in SUI bladder leaks.
A protein interaction between iNOS and IRG1 has been identified as a key regulator of the immune response. This discovery could lead to new treatments for conditions such as cardiovascular disease, arthritis, and Crohn's disease.
Young people aged 16-25 are three times more likely to start drinking alcohol than non-alcohol alternatives, according to new research from the University of Sheffield. Despite concerns about a potential 'gateway' effect, no evidence was found that no/lows impact young people's alcohol consumption.
A research team from China has developed a material with high charge-to-spin conversion efficiency, achieving record-breaking performance in spintronic devices. The discovery utilizes nonsymmorphic symmetry to stabilize the material and enables ultra-low power magnetic switching.
A research team developed an innovative method to analyze histone modifications during cell division, revealing three distinct phosphorylation programs that follow a clear temporal sequence. The study refutes the previous assumption that removal of certain chemical groups from histones is crucial for DNA compaction.
The upper-level subtropical westerly jet over East Asia shows a weakened long-term trend under orbital forcing but strengthens under greenhouse gas forcing. This study challenges the simple assumption that warming means weakening and suggests the jet could become stronger under future global warming.
Researchers identified 16 clinical laboratory markers linked to PTSD, including cholesterol and glucose levels, liver indicators, and red and white blood cell counts. These biomarkers may reveal the physical impact of PTSD on the body, supporting timely interventions to mitigate chronic disease risk.
A research team developed an implantable sensor to monitor dynamic H₂O₂ levels in plants, enabling real-time tracking of plant stress responses. The system achieved high time resolution and maintained stable performance under various conditions.
A new study published at the Pediatric Academic Societies Meeting found that adolescents with high social media use had triple the odds of recent alcohol use compared to non-users. The study suggests that digital literacy and safe online navigation are crucial in reducing exposure to alcohol-related content.
A new research study by Australian energy companies and waste management firms has shown how organic waste can be safely turned into clean gas for homes and businesses. The team identified critical specifications for optimal biomethane quality, making it more cost-effective to produce.
New findings suggest that clopidogrel monotherapy is associated with a lower risk of net adverse clinical events compared to aspirin monotherapy, even in patients at high risk of bleeding. This benefit is more pronounced in patients with high bleeding risk and complex procedures.
A cohort study of 6,802 pregnant women found an inverse association between grip strength and the risk of hypertensive disorders of pregnancy. The study suggests that relative grip strength may be a useful tool for risk stratification of HDP.
The study found that outpatient care for youth is driving the growth, with nicotine, cannabis, and opioids being the most common substances. Despite this, alcohol-related visits have declined in all care settings over the past 16 years.
A new study found that electronic provider notifications significantly increased aortic valve replacement rates and improved survival among older patients with severe symptomatic aortic stenosis. The DETECT-AS trial showed that clinicians who received automated email alerts with abnormal heart ultrasound results detected AS were more l...
Researchers reveal how expansion of bone marrow fat promotes immunosuppressive PD-L1 signaling, leading to enhanced osteoclast activity and accelerated bone loss. Reducing bone marrow fat improves bone structure.
A cohort study found that bereavement was associated with increased cardiovascular disease risk both before and during the COVID-19 pandemic. The strongest association was observed for partner or sibling loss during the pandemic, highlighting the importance of targeted clinical monitoring and preventive care for bereaved individuals.
Researchers at Griffith University and Queensland University of Technology have developed a machine-learning model to design efficient urea catalysts using waste gases. The model accurately predicted key co-adsorption energy values, narrowing down over 1,400 candidates to promising ones.
This research explores how vibration can convey emotional qualities like reassurance and encouragement, as well as represent abstract experiences through touch. The findings highlight the potential of vibration as an alternative to sound-based navigation for blind and low vision people.
A novel blood return system has been shown to significantly reduce blood loss during pulmonary embolism procedures, with a median reduction of 97%. The study found that the system improved procedural efficiency and maintained hemodynamic efficacy without added therapies or major complications.
Young scholars explore how to make clinical decisions from biomarkers to immunotherapy. They present innovative approaches for targeted therapy sensitivity and guidelines, shedding light on neoadjuvant care.
A new study found that infants receiving maternal RSV vaccination or Nirsevimab after birth had significantly lower RSV infection rates and fewer severe complications. The study showed a high uptake of the vaccines among pregnant patients and newborns, leading to declining rates of RSV-related illnesses.
A new study found that COVID-19 significantly worsens cardiovascular outcomes, leading to higher one-year mortality rates in patients with severe heart attacks. Patients who survived a heart attack and experienced COVID-19 had a 25% higher one-year mortality rate compared to those without COVID-19.
A pilot study of 100 exclusively breastfeeding women found that maternal dairy intake is associated with decreased concentrations of numerous human milk lipids. The study suggests a link between healthy dairy intake and lower levels of specific milk lipid species, which may have implications for infant health.
New research suggests exposure to fathers' depression in pre-adolescence is associated with poor educational outcomes among males, but not females. Early identification and family-centered support can help promote school success and long-term well-being for affected sons.
Researchers found that obakulactone reduced joint swelling, restored cartilage structure, and improved immune organ function in RA rats. It also suppressed proinflammatory cytokines and shifted macrophage polarization to anti-inflammatory M2.
Researchers developed Plan & Protect, a technology-guided safety planning program for rural youth with suicidality seeking care in emergency departments. The program aims to enhance accessibility and usability of safety planning in resource-limited settings, supporting more effective crisis care for adolescents in rural communities.