Researchers have developed a way to quickly create customizable synthetic blood vessel grafts in just minutes using additive manufacturing. The new technique, called Focused Rotary Jet Spinning, allows for precise control over diameter and wall thickness, making it ideal for acute trauma situations and complex pediatric heart surgeries.
Researchers found that hepatitis E virus particles can attach to and release from mouse cells, but viral genetic material remains unpacked. This discovery improves understanding of the host range and could pave the way for a mouse model to study the disease and test therapeutic approaches.
A new review proposes a paradigm-shifting framework to address the growing threat of Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP). The framework highlights the importance of considering virulence phenotype over co-detection of resistance genes and virulence markers.
A remarkably preserved Cretaceous mammal fossil in Mongolia's Gobi Desert is rewriting the chapter on mammal evolution. The discovery, published in Nature, reveals that zhelestids were not close relatives of modern placental mammals, but rather a distinct group of early mammals.
A new study reveals that only 2% of FHA loans and 5% of VA loans went to Black borrowers during this period. This exclusionary lending practice came at a time of increasing racial segregation and preceded the widening of the racial wealth gap in the US.
Researchers at the University of Illinois developed a gene editing tool to treat Huntington's disease by altering a specific point in the huntingtin gene. The treatment reduced toxic protein fragments, symptoms, and brain degeneration in mice, providing a new approach for treating genetic diseases.
The study presents a novel method for synthesizing fluorescent polymer nanoparticles (FPNs) using microwave irradiation, enabling precise regulation of particle size and fluorescence wavelength. The approach achieves a 24-fold improvement in reaction efficiency compared to traditional thermal polymerization methods.
A novel dynamic imine bond adhesive technology enhances commercial filters with improved particle retention and filtration performance, increasing efficiency and lifespan by up to 10-30% and extending filter lifespan by nearly a factor of two.
Research highlights importance of cardiovascular care in breast cancer patients and survivors throughout life. Cardiovascular risk factors and interventions are essential to prevent disease progression and improve quality of life.
A study led by CNIC suggests that intensive cardiac surveillance may have limited clinical value for lymphoma patients with low to moderate cardiovascular risk who are treated with anthracyclines. Nearly half of the patients met criteria for cancer therapy-related cardiac dysfunction, but most abnormalities were mild and transient.
A 16-week personalized exercise intervention improved glycemic regulation, physical fitness and reduced abdominal fat while increasing skeletal muscle mass. Cognitive impairment also showed significant improvements in working memory, perceptual speed and executive function.
A new study found a national mass drug administration (MDA) program drastically reduced scabies cases in Solomon Islands and Fiji by over 80%. The MDA, which involved ivermectin treatment, also decreased rates of skin infections and moderate-to-severe scabies.
A new study from King's College London identifies widening ethnic and socioeconomic inequalities in stroke, with higher rates of diabetes and hypertension among black African and lower socioeconomic groups. The research calls for targeted and earlier primary prevention efforts to reduce these disparities.
A new study from the University of Colorado Anschutz found that oral semaglutide reduced heavy drinking and alcohol-related harm in adults with Alcohol Use Disorder. The medication, commonly used for diabetes and weight loss, showed consistent reductions in harmful real-world drinking behavior.
Researchers at Colorado State University have developed a catalytic process to transform carbon dioxide into recyclable, high-performance materials. These new materials can replace today's plastics in many situations and feature sought-after characteristics such as high mechanical strength and flexibility. The foundational building blo...
Invasive species, such as Opuntia stricta and little fire ants, are displacing communities globally. At least 123.2 million people were forcibly displaced at the end of 2024, with food insecurity and competition over resources being major drivers.
Researchers have developed a new method to handle and transfer ultra-thin materials, using ordinary kitchen cling film to solve the problem of cracking. This breakthrough enables the creation of large-scale fabrication of 2D material-based devices and opens up new opportunities for studying novel physics in condensed matter systems.
LorMe is an open-source R framework designed to provide a unified approach for standardized microbiome analysis. The platform enables seamless data exchange with widely used microbiome analysis packages, allowing diverse analytical approaches to work together while maintaining flexibility and transparency.
Researchers at the University of Minnesota developed a new strategy to accelerate the breakdown of compostable PLA plastics under everyday composting conditions. The addition of a trace amount of 2-sulfobenzoic acid cyclic anhydride (SAn) dramatically enhances their hydrolytic degradation, making them more suitable for home composting.
Researchers develop a new photocatalytic material by engineering sulfur defects in ZnIn2S4 nanosheets using pulsed laser ablation. The defect-rich nanosheets show a 15-fold enhancement in converting CO2 to carbon monoxide.
The PIEM concept introduces a new framework for studying persistent intracellular extraintestinal microbes, which reside within internal tissues and cells. Microbiome research has long focused on barrier surfaces, but PIEMs offer fresh perspectives on host–microbe relationships and the pathogenesis of complex diseases.
Researchers at the University of Manchester have developed a new family of antifungal agents that are more potent and less toxic than existing treatments. The compounds, which were discovered through genome mining, showed increased antifungal activity and improved solubility compared to existing drugs.
This study analyzed 9845 Ukrainian refugee children aged 5 and under in Southern Poland, identifying 5 distinct health care utilization profiles. The findings suggest that refugee-hosting countries must prioritize emergency and inpatient care following a crisis to rapidly adapt health care resources.
Nearly 23 million Americans with high blood pressure may be eligible for treatment according to the 2025 American Heart Association/American College of Cardiology guideline. Lifestyle changes are key, but medication can save thousands of lives if prescribed and combined with lifestyle modifications.
Scientists have developed a table-top technique using all-attosecond transient absorption spectroscopy to study the oscillatory motion of an electron vacancy in xenon ions. The results provide insights into the underlying dynamics of light-induced processes.
Researchers at TU Wien developed a novel catalyst converting nitrate from wastewater into ammonia using sunlight and electricity. The MXene-Gold material interacts optimally, capturing light and heat while facilitating chemical reactions.
Researchers found that an AI-enabled early warning system identified patients at risk of rapid clinical decline sooner, contributing to fewer deaths. The study evaluated over 23,000 high-risk patients and showed a 18% reduction in the risk-adjusted odds of in-hospital death
Project Remission challenges the notion that chronic disease is inevitable by highlighting evidence that remission may be achieved through lifestyle interventions. The project features educational content, clinical evidence, and practical frameworks to help health systems translate research into routine clinical practice.
A new mathematical approach using optics helps computers solve larger, more complex optimization problems by reducing computational demands. The framework can be applied to various real-world challenges, including facility placement and data clustering, with potential benefits for a carbon-neutral future.
A new study has mapped landslide hazard zones across the US, revealing that 6.5 million Americans live in areas prone to landslides. The research highlights a significant urban-rural divide in disaster preparedness, with rural residents facing greater challenges in recovering from such events.
Researchers from Virginia Commonwealth University have uncovered a protein, TRNAU1AP, that helps glioblastoma cells survive and multiply. Targeting this protein could make cancer cells more vulnerable to treatment, potentially leading to improved survival rates.
ISM6331, a novel pan-TEAD inhibitor, has received Fast Track Designation from the FDA for treating adult patients with unresectable malignant pleural mesothelioma. The treatment boasts synergistic anti-tumor effects and potential to overcome drug resistance as combination therapy.
A new survey finds Orange County's governor race virtually tied, with the top issue being the cost of housing. The poll also reveals an increasing divide by generation and gender, yet an electorate converging on fixing housing costs. This leaves Democrats and Republicans scrambling to assemble winning coalitions.
European oil beetle larvae emit floral scents to attract wild bees, allowing them to sneak into nests and feed on eggs and food stores. The larvae produce the substances themselves through specific cytochrome P450 enzymes.
University of Warwick researchers and Verdel Instruments have successfully demonstrated two-dimensional mass spectrometry on a benchtop instrument, making this powerful technique accessible for everyday laboratory use. The Q-2DMS method preserves up to tenfold more usable spectral information when analyzing closely related or near-isob...
A review article published in the Journal of Environmental Psychology found that nature can enhance cognitive performance and emotional well-being even in the absence of prior stress or depletion. The study analyzed 54 studies and consistently reported positive effects on attention, positive affect, and well-being from a neutral baseline.
Researchers at Max Planck Institute have discovered that mechanical strain can induce chirality in previously achiral materials. By applying controlled strain, the team can create left- or right-handed structures, opening up new opportunities for controlling mechanically reconfigurable materials.
A new experiment by PSI researchers eliminates the possibility of transformation into mirror particles, ruling out a mirror world. This finding is crucial for particle physics, as it restricts speculations and encourages exploration of new avenues.
Researchers found that the Agulhas Current supplies heat and moisture that strengthen weather systems, causing severe floods in the Western Cape. In contrast, the Benguela Upwelling System has a minor role in intensifying rainfall.
High LDL-C led to 3.6 million deaths and 90.7 million disability-adjusted life years in 2023, despite declining mortality rates. The absolute burden increased due to population growth and aging, with regional disparities emerging.
A new study finds that climate change has slightly increased malaria overall, but rising temperatures could increase risk in southern and East Africa while reducing it in warm regions like West Africa.
Researchers developed boron-doped carbon nanotubes to boost NO3- reduction reaction performance, achieving high ammonia yields and positive-shifted onset potentials. The doping strategy offers a new way to tune complex electrocatalytic reactions.
Researchers developed ultrasound-responsive microspheres that release rhBMP-2 on-demand, promoting bone regeneration. The microspheres exhibit remarkable stability and trigger drug release via low-intensity ultrasound.
A new USC study found that LA County residents in evacuation zones experienced heightened levels of anxiety and depression after the 2025 wildfires. The effects were greatest among those facing social and economic hardship, highlighting the need for policies to bolster housing security and community support networks.
Researchers in India have identified β-esterase as the primary enzyme involved in α-cypermethrin detoxification, showing increased reactivity in response to the insecticide. This finding suggests that mosquitoes can dramatically increase production of a particularly effective enzyme when exposed to a threat.
The HULU framework accelerates clean energy materials discovery by integrating machine learning potentials with adsorption simulations. Researchers found that universal machine-learning potentials are reliable across different chemical systems, providing a roadmap for material screening.
A team of researchers has discovered that supermassive black hole winds are 100 times more powerful than previously thought, carrying energy across 300,000 light-year distances. This finding demonstrates the explosive winds' impact on space beyond galaxies.
A survey of 3,013 people found that 66% of respondents are influenced by animal welfare when making purchasing decisions. Shoppers would pay an average of £1.31 per week for improved farm animal welfare, with specific increases for eggs (£1.61), milk (£1.13), and beef (£0.46).
The study reveals that the amount of available resources determines whether an organism relies on its memory or makes decisions based on current sensory input. Memory becomes most useful when sensory information is moderately uncertain, providing a significant improvement in performance.
A phase 3 trial found that deramiocel, a heart-derived cellular therapy, slowed muscle weakening and preserved heart function in boys and young men with advanced Duchenne muscular dystrophy. The therapy also showed promise in reducing scarring in the heart.
A new fossil species, Eoceras shaanxiense, has been discovered in the early Cambrian of South China, providing insights into the earliest known siphuncle-bearing cephalopods. The find represents an intermediate evolutionary stage between earlier species and later species with more developed buoyancy systems.
Researchers have created an AI model that accurately predicts cardiac index, a metric used to evaluate heart function, using non-invasive sensors on patient skin. The system demonstrates potential for accessible cardiovascular assessment beyond major hospitals and specialized clinics.
The American College of Chest Physicians' open-access journal CHEST Critical Care has received its first Journal Impact Factor of 2.7, reflecting the dedication of its authors, reviewers, and readers. This recognition highlights the journal's growing impact in critical care medicine.
Researchers propose using a simple GKI test to track metabolic health in noncommunicable diseases like cancer and cardiovascular disease. The test measures glucose to ketone ratio and may help assess nutritional ketosis and adherence to metabolic interventions.
Researchers have developed a lightweight receiver that captures energy from laser beams and converts it into electricity, enabling wireless charging of drones in mid-air. The technology uses a perovskite laser cell-thermoelectric tandem device to generate power, overcoming the challenge of battery life for long-duration missions.
A research team developed a bioceramic material that releases magnesium ions in accordance with the stages of osteoporotic fracture healing, suppressing inflammatory immune responses. The study suggests advanced fracture treatment materials could regulate immune responses to promote bone regeneration.
Researchers discovered a small mutation in the RBM20 protein leads to vastly different disorders in heart muscle cells. The study identified molecular targets for patient-specific therapies and potential new active substances.
Researchers discovered a structural aberration in octopus ribosomes that enhances accuracy and reduces errors in protein synthesis. This finding may be linked to the evolution of the octopus's complex sensory system, which includes a highly sensitive 'taste by touch' system.
This new section in JMIR Pediatrics & Parenting explores the modern shift to data-driven parenting with digital technology guiding parental planning. Research topics include the impact of wearable devices, AI-powered apps, and tracking on child health outcomes, parental well-being, and the parent-child bond.
Researchers have developed a fully flexible sensing-memory integrated system for wearable physiological sensing, which integrates a pressure sensor with a floating-gate organic thin-film transistor memory. The device offers a short response time and long data retention capability compared to previously reported OTFT-based pressure sens...