Scientists have unveiled a new structure of the kinesin-1 protein, showing how cells control its on-off switch. The discovery could shed light on incurable neurodegenerative diseases such as ALS and Charcot-Marie-Tooth Disease Type 2.
Researchers developed a hybrid technology combining human learning and machine learning in noninvasive BCIs, producing rapid and sustained gains in motor imagery control. The study demonstrates significant scientific and technological advancement in BCIs, establishing a scalable pathway toward robust neural interfaces.
A new species of colobus monkey, 'Likweli', has been identified by its distinctive facial markings and unique call. The rare species is found in the dense forests of Lomami National Park and is considered Endangered due to its small geographic range and population size.
A previously unknown species of African monkey, Colobus congoensis, has been identified in the Democratic Republic of Congo. The species, known locally as Likweli, features a distinctive orange face patch and is one of the rarest discoveries in modern primatology.
Scientists have discovered that marsupial forelimbs rapidly develop over a four-day period, challenging current understanding of limb development in vertebrates. This finding highlights the unique biology of marsupials and has important implications for conservation efforts.
Researchers developed a new way to uncover differences in how viruses infect and destroy individual microbial cells. The study used a mathematical modeling framework to analyze infection outcomes in individual cells, revealing striking accuracy and new insights into viral behavior.
Researchers have developed a new drug candidate, SB-0110, that boosts L-dopa's benefits while reducing dyskinetic side effects in animal models of Parkinson’s disease. The compound preserves the gene-activity patterns tied to L-dopa’s benefits while counteracting biological changes associated with dyskinesia.
A study published in PLOS Climate found that teleworking can reduce carbon emissions from commuting, but this benefit may be offset by increased utility use at home. More frequent and separate home office users produced higher emissions due to work-related housing and technology use.
Researchers found that providing honeybees with prebiotics and probiotics helped them survive thermal stress. The study suggests these nutritional supplements can buffer the survival of bees and improve antioxidant enzyme activity.
A groundbreaking study published in Science Translational Medicine has successfully restored the sense of touch in individuals with spinal cord injuries using brain-computer interface technology. The study found that electrical pulses delivered to the somatosensory cortex remained stable and localized over a period of up to 10 years, w...
Researchers from the University of Tokyo used limpet shell analysis to reconstruct the journeys of tiny creatures between hydrothermal vents, finding they explore sunlit upper ocean during larval stage. This discovery helps explain how animals living at isolated vent sites can spread over hundreds or thousands of kilometers.
A New Jersey meteorite contains high concentrations of salt and briny fluids that can create molecules vital for life on Earth. The discovery sheds light on the chemical origins of life on our planet.
The Trump administration's 2025 repeal of the US Roadless Rule could put 25 million Americans at risk due to loss of access to pristine watersheds. The study assesses the value of this rule for both human health and nature.
Researchers reconstructed past methane concentrations using clumped isotopes in air from the past, revealing significant changes since industrialization began. The study suggests human activities are disrupting the balance between methane emissions and breakdown, driving rising atmospheric methane concentrations.
Researchers have developed ultrathin, invisible on-skin electrodes that can measure biological signals without altering appearance or social interactions. These new sensors achieve this by closely matching the appearance and texture of natural skin, reducing reflections and eliminating visibility.
A study analyzing county-level data reveals broad geographic patterns and local factors influencing breastfeeding initiation in the US. Localized approaches addressing disparities in breastfeeding initiation are necessary to complement national policy efforts.
A German analysis explores how COVID-19 disrupted typical transmission patterns of respiratory diseases, leading to shifts in their seasonal surges. The study found that population-level loss of immunity after the pandemic caused a buildup of susceptible hosts, resulting in earlier peak weeks for these surges.
Researchers confirm discovery of new African monkey species Colobus congoensis, previously unknown in over 75 years. The species is distinct from other African colobus monkeys with unique cranial, dental, and skeletal characteristics.
A study in PLOS One identified T. rex as the likely cause of some tooth marks on fossils from Cretaceous-era Wyoming, providing insights into animal behavior and ecosystem dynamics. The researchers developed a guide to interpret tooth traces on fossils, distinguishing between natural and bite-related marks.
A study analyzing 30,527 English dementia patients found hospital readmissions associated with multiple factors including sex, health conditions and post-discharge care. The research highlights the importance of monitoring and managing these risk factors to prevent hospital readmissions.
Researchers found that horses' heart rates increased when viewing wolves, regardless of behavior, while keeping a poker face and not displaying overt behaviors. The study's findings have implications for horse welfare and rider safety, as horses may be experiencing internal agitation without physical signs.
A new analysis of over 110,000 papers submitted to Science and Science Advances reveals Western scientists, larger teams, and top-ranked universities have slight advantages in acceptance rates. The study provides insights into editorial dynamics and outcome disparities, shedding light on the peer review process.
A new study from Griffith University reveals how different cave environments leave distinct 'fingerprints' on skeletal remains, providing a powerful tool for reconstructing past environments and histories in challenging conditions. Bones preserved in underwater caves often preserve their structure and surfaces remarkably well, while un...
A University of Colorado Boulder-led study analyzed over 110,000 manuscript submissions to top-tier scientific journals, revealing that prestige, topic, and location matter most in determining publication. The study found a significant disadvantage for authors based in China and those studying social sciences.
Researchers analyzed isotope data from over 100 individuals to find that some societies relied heavily on maize grown within diversified agricultural systems. These communities developed resilient polycultural food-production systems combining domesticated crops with wild plants and local ecological knowledge.
Researchers have found four exoplanets orbiting Barnard's Star, all smaller than Earth and Venus, but larger than Mars. The planets' composition suggests they are rich in magnesium, which creates periclase, a mineral that does not store water effectively.
A new study from the University of Michigan highlights the limitations of framing loneliness as a solely medical issue. Chronic loneliness and social isolation are linked to higher risks of disease, death, and economic costs, but experts argue that healthcare alone cannot rebuild social ties or address underlying social issues.
Researchers at MIT have created a precise way to engineer artificial blood vessels by mechanically stretching and pulling a "blood vessel on a chip". The new method, reported in the Proceedings of the National Academy of Sciences, enables controlled sprouting of new vessels and programming of their growth patterns.
Researchers have identified a new fungal species, Semicentenialea rex, representing a new class of fungi called Semicentenialomycetes. The fungus was isolated from roots in Sweden and has unique characteristics that set it apart from other rust fungi.
Dr. Rui Yang receives a Burroughs Wellcome Fund Career Award for Medical Scientists to uncover genetic causes of life-threatening immune disorders and identify new treatment paths. The research aims to advance diagnosis and understanding of rare diseases while fostering the next generation of scientists.
Researchers at Texas A&M University designed a fictional hospital to demonstrate the business case for investing in better design. The model shows that by incorporating evidence-based design strategies, hospitals can recover their additional construction costs within two years and achieve over $100 million in net financial gains over t...
A Johns Hopkins Medicine team created a computational model to forecast which patients with hepatocellular carcinoma (HCC) will benefit from combination treatment using immunotherapy and targeted therapy. The spatial QSP modeling platform accurately predicted response rates for virtual patients, demonstrating its potential to inform pe...
Reducing carbon dioxide concentration improves microbial production of biodegradable plastic, such as poly[(R)-3-hydroxybutyrate]. Lower CO2 levels trigger adaptive cellular responses that enhance carbon utilization efficiency.
The Brain & Behavior Research Foundation recognizes six early-career scientists for their outstanding contributions to mental health research, including Dr. Joline Fan's work on brain circuitry and personalized neuromodulation therapies, and Dr. Nili Solomonov's development of scalable neuroscience-informed psychotherapies for depression.
Researchers discovered that reducing microglial activity worsened abnormal electrical activity and increased seizure-like events in a mouse model of Alzheimer's disease. Microglia are not just drivers of inflammation but also perform important housekeeping functions to maintain healthy brain activity.
Researchers created a tool that leverages large language models to build novel languages with unique grammatical structures and vocabularies. The ConlangCrafter tool generates diverse languages, which can be used for creative applications such as video games and movies, or aid researchers in studying poorly documented languages.
Research from the University of Reading shows that cutting air pollution globally can strengthen the Indian monsoon, increasing rainfall by 0.28 millimetres a day across the country. The study found that regional action alone can have the opposite effect, reducing rainfall in parts of India.
Researchers have developed a systematic cross-calibration method for GPS satellite data, producing a long-term dataset that spans two full solar cycles. The calibrated dataset provides a reliable resource for studying relativistic electrons in medium Earth orbit, enabling more accurate predictions of electron flux enhancements.
A University of Stirling study found that most people in the UK don't fully understand dog laws and often believe stronger protections exist than actually do. Dog owners were consistently more confident but not more accurate in their knowledge, raising concerns about improving legal understanding.
A team of researchers from the University of Münster and RIKEN research institute has discovered a previously unknown mechanism for salt tolerance in plants. They found that a particular chemical mark in the 'histone code' plays a crucial role in adapting to salt stress.
Researchers developed a new computational approach to identify genes that characterize different cellular states from mRNA-seq data, offering more accurate and interpretable analysis of complex biological data. The Cartesian Distance-Based Gene Expression (CDBGE) algorithm was evaluated using multiple publicly available datasets, demon...
Researchers at Shaanxi Normal University have developed a novel titanium-chromium nitride catalyst that efficiently traps and rapidly converts polysulfides, key to improving Li-S battery efficiency. The new material demonstrates exceptional stability and effectiveness in suppressing the shuttle effect and enhancing conversion efficiency.
Researchers at ISTA discover how to turn single molecules into effective magnets, overcoming weak magnetic field limitations. The findings could lead to breakthroughs in nanoelectronics and the design of single-molecule nanodevices.
The Monell Chemical Senses Center has signed a 20-year lease to relocate and expand its operations to One uCity Square. The new facility will provide world-class support for sensory science discovery and strengthen Philadelphia's life sciences ecosystem.
Researchers developed DeepHHF, an AI model that identifies patients at high risk of heart failure up to five years in advance. The model analyzes standard ECG recordings and detects subtle abnormalities that are often imperceptible to the human eye.
The study identified specific climate measures for each city type, including infrastructure investment in heat protection, urban greening, and transport transition. Rapidly growing cities like Tirana and shrinking cities like Daugavpils benefit from nature-based solutions and infrastructure upgrades.
A new study found that students and staff involved with collegiate recovery programs held varying definitions of harm reduction, which shaped their perspectives on integrating it into CRPs. The study suggests opportunities to reframe harm reduction in a way that builds common ground and meets students' diverse recovery needs.
Researchers developed a new molecular strategy to control the critical interface in perovskite solar cells, resulting in a power conversion efficiency of 26.19%. The approach reduced interfacial disorder and nonradiative voltage losses while improving charge carrier transport.
A novel measurement cell enables in-situ/operando X-ray absorption spectroscopy measurements under high pressures and temperatures, providing new insights into thermocatalytic processes such as the Fischer-Tropsch synthesis. The setup is suitable for investigating catalytic gas-solid reactions under realistic operating conditions.
A USF study has identified South Florida as a crucial feeding ground for Atlantic tarpon, highlighting the importance of the region to the species' migrations. The research found that tarpon rely on distinct 'foraging landscapes' and can travel hundreds of kilometers to find food.
Researchers at Tsinghua University Press have created MXene-PVDF textiles that offer enhanced thermoregulation for adaptive personal protection, while also providing safe Joule heating. These materials are promising for wearable personal protection in extreme temperatures, enabling workers to operate safely and efficiently.
A specific subgroup of neutrophils signals the immune system to dial down its response, allowing regeneration. The study shows that the fine regulation of inflammation is crucial for healing and that unleashing the right signals can reactivate nerve regeneration.
A new study published in Environmental Research Letters found that climate mitigation and adaptation strategies often lack real-world data, hindering effective climate policy. Researchers identified the need for systematic collection of observational data across cities to determine what truly works, under which conditions, and for whom.
Researchers explored how AI and metabolic modeling can inform effective biocontrol strategies to combat antimicrobial resistance in built environments. Microbial biocontrol using 'good' microbes has shown promise, but inconsistent outcomes are due to various factors, including genetic differences and environmental stressors.
Post-Soviet Estonian films tend to focus on victimhood and resistance, while ignoring the Holocaust and collaboration with Nazi forces. Films like Awakening and In the Crosswind address deportation complexities, while others draw connections to the Holocaust for international audiences.
An international team of scientists developed a novel, catalyst-free plastic recycling process that uses only water and oxygen to convert various types of plastic waste into high-value organic acids. The method achieved near-complete conversion with minimal environmental impact.
Scientists have discovered that oxygenic photosynthesis is possible with only one photosystem, overturning a long-held assumption in biology. The study, published in Nature Communications, shows that the absence of one photosystem can be compensated by an alternative mechanism.
Researchers discovered that cyanobacteria band together into protective flocs when attacked by predators, a survival strategy that could influence how carbon is stored in the world's waters. This behavior helps explain why cyanobacteria invest energy in forming flocs despite the apparent cost to their growth.
Incorporating structured, video-enhanced feedback into training programs halves prescribing errors by newly qualified doctors. This approach closes the performance gap between novice and experienced prescribers, demonstrates cost-effectiveness and scalability.
Researchers at the Hebrew University of Jerusalem have found that plants can successfully manufacture β-casein, one of the major proteins in cow's milk. The protein accumulated in an unexpected location inside plant cells, revealing a previously unknown pathway that could help improve animal protein production in crops.