A new method for three-dimensional visualization of nanoplastic distribution in the neonatal mouse brain has been established, revealing particle-size-dependent biodistribution patterns. The study found that smaller particles (50 nm) were widely distributed throughout the brain, while larger particles (500 nm) showed weaker accumulation.
Juno's Microwave Radiometer reveals Io's heat output by looking below the surface, breaking new observational ground for volcanic and icy worlds. The findings suggest a steep gradient of rising temperatures just several feet into Io's surface, with possible explanations including conductive crust heating or cooling lava flows.
The VALOR project aims to co-develop a comprehensive approach to understanding the impact of pollinator decline on food systems. A new collection in the Research Ideas and Outcomes journal provides an open-access hub for researchers, policymakers, and practitioners to access outputs and tools related to pollinator conservation.
A multidisciplinary study has identified a novel biofilm regulatory protein called Biofilm Architecture Regulator (BatR) and its role in Pseudomonas aeruginosa infections. The discovery may lead to new targets for anti-infective treatments, including those for people with cystic fibrosis.
Researchers at Duke University developed an AI framework called Raygun that can create modified versions of proteins while preserving structure and function. The tool uses protein language models to make extensive changes to existing proteins, opening up new avenues for engineering customized-sized proteins.
Researchers have developed an oxidation-free approach to oligonucleotide synthesis using P(V)-fluoridates, enabling rapid coupling and automated synthesis. The new platform offers improved efficiency and stability compared to conventional methods.
Researchers at UMass Chan Medical School have developed a microRNA-based gene therapy that suppresses mutant SOD1 production, delaying disease onset by 60 days and extending lifespan by 100 days in mice models of ALS. The therapy, delivered via adeno-associated virus (AAV) vector, preserves motor neurons and maintains neuromuscular con...
Researchers have developed a tool to design synthetic disordered proteins, untangling their functionality. This innovation accelerates the exploration of biology's vast and underexplored area.
Researchers developed a thermal engineering method to modify ZnMgO nanoparticles, reducing oxygen vacancies and increasing nanoparticle size. This approach improved QLED electroluminescence uniformity, brightness, and stability, tripling the device lifetime to 20,000 hours.
Researchers from Tsinghua University Press outline a roadmap for developing practical single-molecule spintronics devices, offering a pathway toward ultra-compact, low-power spintronic technologies. The review highlights various spin-related quantum effects that have been demonstrated in single-molecule devices.
Researchers discover diffraction behaviors never seen in conventional quasicrystals using a new type of monotile structure. The team's findings open a new direction for exploring the fusion of quasiperiodic order and chirality, with potential applications in light manipulation and optical devices.
Researchers at Science Tokyo developed iron-substituted calcium titanate as an environmentally friendly support material for chemical looping. The material improves CO2 conversion by accelerating ion and electron transport, enabling scalable carbon recycling with abundant, low-cost elements.
A new study found that conspiracy beliefs are more likely to translate into real-world behavior when held with greater certainty or regarded as personally important. The researchers also discovered that viewing conspiracy theories as 'actionable' further amplifies this tendency.
A cross-sectional study identified critical methodological limitations in RCTs of CHM, including unclear hypotheses and inadequate allocation concealment. The study highlights the need for improved planning and conduct of CHM RCTs, with superior designs published in English-language journals.
Researchers found that primates play, groom and care for animals from different species, hinting at social curiosity and readiness to form cross-species bonds. These behaviors may represent evolutionary building blocks for human-animal companionship.
Researchers have discovered that microorganisms actively contribute to mineral formation on the ocean floor, using compounds such as sulfate and sulfur to promote pyrite formation. The study reveals a complex interplay between biological and geological processes at the ocean floor.
Researchers found that immature NK cells in donated cord blood can undermine CAR NK cell therapy by creating false targets for therapeutic cells to attack. Removing these cells before manufacturing improves therapy outcomes, persistence and antitumor activity in preclinical models of lymphoma and ovarian cancer.
Intensive feeding by tourists is altering the island's ecosystem, leading to unusual interactions among animal species. The study highlights the need for careful management of wildlife tourism practices to avoid unintended consequences for the environment.
A project led by Michela Taufer aims to accelerate AI-driven scientific discovery by enabling secure data sharing across the nation's research infrastructure. The National Science Data Fabric (NSDF) will connect researchers, computing resources, and data repositories, making advanced AI-driven science accessible to all.
A new review explores innovative strategies for achieving ultralow-resistance Ohmic contacts in 2D materials, including van der Waals integration and interfacial doping. The study aims to overcome Fermi-level pinning and Schottky barrier limitations, enabling better devices and industrial realities.
A recent analysis found that while genomic testing increased among Medicare recipients, many patients still lack next-generation sequencing tests. This limits their access to precision medicine and targeted therapies. The study highlights the need for further research on how increased testing impacts patient outcomes.
A recent study found that exposure to specific bacteria in barn air can protect against allergies, asthma, and hay fever. Researchers identified two key bacteria, Romboutsia timonensis and Glutamicibacter arilaitensis, which mediate the farm effect through certain receptors.
Women who experience premature menopause are at a higher risk of developing high blood pressure, with the risk peaking among those who reach menopause between ages 25 and 35. The study suggests that clinicians should consider age at menopause as a distinct cardiovascular risk factor for women who reach menopause before age 40.
Researchers propose a user penalty-and-reward system to curb long lines caused by inefficient human queuing behavior. By incentivizing users to choose alternative routes, the system aims to balance congestion with addressing user needs.
Researchers discovered a novel signaling role for smooth septate junction proteins in regulating stem cell growth and preventing tissue disruption. By maintaining spatially localized aPKC enzyme, sSJ proteins prevent excessive intestinal stem cell proliferation.
A new study reveals that lake ice loss accelerates sharply once winter temperatures cross critical thresholds, leaving mid-latitude lakes vulnerable. The researchers found that the melting process accelerates considerably faster than the freezing process as the climate warms.
Scientists have uncovered a new mechanism used by heart cells to resist reprogramming and found that carbohydrate sulfotransferase 7 (CHST7) is the most potent preventer of reprogramming in mouse and human cells. By targeting CHST7, researchers may develop treatments to help the heart fix itself after injury.
The US government's withdrawal of funding for global HIV programs led to a sharp reduction in the number of people entering HIV care across East Africa. New patient enrollment dropped by 59% and viral load testing declined by 33% within weeks, according to findings from researchers at UC San Francisco.
A study by Rice University associate professor Tanika Raychaudhuri found that many Asian Americans learn about politics through social interactions with friends, classmates, co-workers, and neighbors. The research suggests that political identities are dynamic and influenced by evolving social networks.
Researchers propose using AI to track nitrogen flows, improve scientific models, and provide practical recommendations for farmers. This approach aims to rebuild the disrupted nutrient cycle and reduce nitrogen losses while increasing food productivity.
Researchers developed a physics-based framework to predict temperature-driven VOC emissions from automotive paint sludge. Higher temperatures increase the release rate of VOCs, with moderate changes leading to substantial increases in quantity and speed of diffusion.
Researchers from the University of Texas at Austin have developed a new approach to stress testing, which simulates multiple financial risks simultaneously to predict bank resilience. This method outperformed existing stress tests in identifying worst-case losses and captured more severe losses.
A study published in International Journal of Environmental Research and Public Health reveals that mobile addiction services can effectively treat people who use drugs, particularly those disconnected from traditional care. The Mass General Brigham Kraft Center for Community Health model proved successful in improving outcomes and red...
New research suggests that tire microplastics can create environmental hotspots that facilitate the persistence, transfer, and spread of antibiotic resistance genes through cities. The microplastics can develop dense microbial biofilms, release chemicals that select for resistant bacteria, and contribute to oxidative stress.
Scientists at the University of Osaka have created a new technique to build blood supply systems for artificial tissues. They successfully fabricated tubular hydrogel structures with controlled lumen sizes and complex geometries, paving the way for creating vascular models that can investigate the development of fully synthetic tissues.
A new study finds that global inequality has increased by 170-270% since 1960, challenging the idea of catch-up development. The research highlights the role of neoliberal policies and geopolitical strategies in perpetuating core-periphery inequality.
Researchers at UC Riverside identified a genetic marker that controls avocado tree flowering patterns, allowing breeders to determine flower type long before it blooms. This discovery could revolutionize avocado breeding by making decisions faster and more efficient, with potential benefits for high-quality fruit production.
A major study reveals the incidence of acute pancreatitis in South Australia has increased to above the global average, with growth rates highest among women and those living in wealthier areas. The condition is increasingly linked to gallstones and metabolic risk factors, shifting the profile of who is at risk.
The Texas A¼M University research team is developing a new approach to lithium recovery using tiny, fish-like swimming nanorobots that capture lithium ions from seawater. The project aims to create a more efficient and sustainable pathway to access a critical mineral needed for batteries, electric vehicles and energy storage technologies.
A study of 43 fathers, mothers, and newborns found that higher ultra-processed food consumption by fathers was associated with higher birth weights and greater fat accumulation in babies. The quality of the father's diet before conception may influence fetal development.
STS appoints Justine Varieur Turco as its new CEO/Executive Director, tasked with advancing the society's strategic priorities and improving patient outcomes in cardiothoracic surgery. With over 20 years of executive leadership experience, Turco aims to build on STS's legacy and support the specialty's continued advancement.
A new scale developed by University of Arizona researchers helps marketers predict consumer habits by analyzing which era evokes the most nostalgia. The Nostalgia for Eras scale assesses three components: warmth, loss, and idealization, identifying specific decades that evoke strong nostalgic feelings.
The American Gastroenterological Association (AGA) is searching for its next CEO after Tom Serena's retirement. AGA has been recognized for its advocacy leadership, scientific excellence, and innovation under his leadership.
The expert panel's report provides guidance for clinicians and policymakers on addressing intimate partner violence among veterans. The recommendations include broader screening for those at risk of experiencing or using intimate partner violence, as well as education and training for healthcare staff to help them recognize signs.
Research finds that bestselling children's science biographies often portray scientists' abilities as innate, discouraging young readers, especially girls and minority children. The study highlights the importance of growth mindset narratives in promoting motivation and accessibility in STEM fields.
Researchers at MIT developed a new technique called VLASH that allows robots to predict their future position, enabling smoother motions and quicker reactions. This breakthrough doubles the speed of robots performing tasks like pick-and-place and boosts performance in dynamic activities.
Insilico Medicine presents first-in-human Phase 1 study data for its novel AI-designed pan-TEAD inhibitor ISM6331, targeting complex oncogenic drivers like the Hippo pathway. The study assesses safety, pharmacokinetics, and preliminary antitumor activity in patients with advanced mesothelioma and other solid tumors.
Research highlights trade-offs between animal welfare, environmental impact, and food production in the egg industry. Shifting to entirely free-range and organic methods may increase emissions by 60% and land occupation, while cage-free systems could require larger hen populations and increase environmental pressures.
Archaeic human parents likely had to provide constant parental care due to deformed head shapes in fossilized humans. Human babies are born less developed than other great apes, requiring specialized care, and this helps explain the origins of cooperative social behaviors.
Researchers at The University of Manchester discovered that intense electronic excitation can trigger rapid structural changes in metals, driven by electronic entropy. The study found that almost all elemental metals undergo solid-to-solid phase transitions driven solely by this effect.
The Bial Foundation offers funding of up to €60,000 for research on human health in physical and spiritual dimensions. The programme promotes research excellence with a global network of 1,900 researchers.
Researchers at KAIST have developed Stable-GFlowNet, a new AI safety verification framework that uncovers seven times more hidden vulnerabilities in AI than existing methods. The technology is expected to serve as a foundation for developing safer and more trustworthy generative AI models.
The American Society for Nutrition (ASN) has announced the locations for its upcoming annual meetings, NUTRITION 2027 in Las Vegas and NUTRITION 2028 in Boston. The meetings will bring together researchers, clinicians, and policymakers to advance nutrition science and celebrate 100 years of ASN.
A new study reveals that over half of the 100,117 sites listed on the National Register of Historic Places face measurable wildfire exposure. The western United States and regions like Oklahoma, Arkansas, and the southeastern coast are particularly at risk due to climate change.
Researchers review cellulose-enabled hydrovoltaic energy generators that combine intrinsic properties of natural polymer cellulose with emerging mechanisms to generate electricity. Cellulose-based systems achieve remarkable metrics in power density and efficiency across various categories.
Researchers created a cascaded metasurface absorber composite that overcomes fundamental trade-offs in LF microwave absorption materials. The novel design achieves exceptional absorption across P- to C-bands at an ultra-thin thickness of 3.78 mm, with outstanding angular stability and stealth capability.
Researchers analysed stone blocks and bricks from the Dutch East India Company's ship Batavia, revealing the materials came from at least two different quarry areas in what is now Germany. The study used advanced geochemical techniques to trace the origin of the cargo, uncovering hidden details about global trade routes.
The partnership will create a blueprint for fusion testbed and shared technology development, addressing key gaps in the DOE Fusion Science and Technology Roadmap. The collaboration combines ORNL's expertise in fusion science with REV's technical knowledge and specialty in capital and ecosystem development.
Researchers found that queen pheromones inhibit daughters' ovarian development during a critical stage of development, while also indicating the queen's reproductive health, leading to more likely retention of helpers. This study provides new insights into how cooperation evolved in insect societies.
Researchers from the University of East Anglia examine how heat and daylight patterns transform urban life, highlighting unequal impacts on social groups. They emphasize the need for urban planning to consider bodily and temporal perspectives, integrating social justice considerations into climate adaptation efforts.