Researchers discovered a new brain hormone GnIH that directly inhibits the action of gonadotropin-releasing hormone (GnRH), stimulating the reproductive system. This finding suggests that GnIH plays a similar role in humans and other mammals, offering potential new treatments for infertility and precocious puberty.
The genetic code of marsupials has been documented for the first time, revealing insights into mammalian immune system evolution. The analysis of the gray, short-tailed opossum's genome found that an important cluster of immune genes, known as MHC, was likely present in ancestral mammals and has since fragmented into multiple chromosomes.
A study found that the Hh pathway in insects determines whether adult stem cells are fated for fat or bone, with implications for treating osteoporosis, diabetes, and obesity. The researchers also discovered that drugs targeting this pathway could potentially build stronger bones while reducing fat.
Scientists have discovered that global warming led to drastic changes in ancient forests 55 million years ago, including the appearance of tropical plants from Europe. This finding has implications for understanding the evolution of modern primates and their adaptations.
Researchers found that morning cells set pace for entire system, resetting evening clock daily without changing its intrinsic speed. Flies' circadian clocks are conserved with mammals, but studying them provides valuable insights into human brain anatomy.
Researchers discovered that bacteria and elephants consume energy at a similar rate per unit mass, regardless of their body size. This finding suggests that living organisms can overcome physical limitations by adapting to their own biochemical characteristics.
The study found that muskoxes were genetically more diverse before the Pleistocene/Holocene transition, with extinct haplotypes only found in northern Asia. The authors suggest that reduced genetic variability may have contributed to the extinction of other great mammals like mammoths.
Research suggests that increased oxygen levels in Earth's atmosphere led to the emergence of large placental mammals, including massive sloths and saber-toothed cats. The study, published in Science journal, uses deep-sea core samples to track changes in oxygen content over 205 million years.
Researchers discovered that photolyase uses energy from visible light to repair UV damage in plants and animals, with water playing a key role in the process. This enzyme is missing in humans and other mammals, making them more vulnerable to skin cancer.
The discovery of avian flu in a new family of mammals highlights the possibility that the virus may be capable of infecting other mammal species. Critically endangered civet cats in Vietnam are at risk due to lack of screening, prompting concerns for biodiversity hotspots.
Researchers at Duke University identified a novel virulence factor in Yersinia pestis using the C. elegans worm model, which mimics mammalian infection mechanisms. The discovery could aid in developing strategies to protect humans from plague and improve understanding of innate immune responses.
A team of scientists proposes rewilding vast ecological history parks with large mammals from Africa, aiming to revitalize ecosystems and create jobs. The plan could fill gaps in the web of interactions between species, restoring diverse ecosystems and promoting biodiversity.
Researchers found accelerated chromosomal evolution since dinosaurs disappeared, with rates of change increasing 2-5 fold. The study identified segmental duplication around breakpoint sites, potentially linked to human diseases like cancer.
The study identified key factors contributing to large mammal extinction, including biological disadvantages and human impact. Smaller mammals are more vulnerable due to limited distribution sizes and exposure to humans, while larger animals face additional challenges such as long gestation periods and late weaning ages.
A new UF study suggests that mitochondrial mutations leading to programmed cell death could be a central mechanism driving aging in mammals. The research finds no correlation between oxidative stress and increased mortality, contradicting the previously believed 'vicious cycle' theory of aging.
Researchers at NYU's Center for Comparative Functional Genomics discovered that thousands of genes in the fruit fly genome are regulated by microRNAs, with 70% having a predicted biological function. The study suggests a larger role for microRNAs during evolution and could explain differences between species.
Researchers found that newborn dolphins and orcas remain active 24 hours a day in the first month, unlike all other mammals. This allows them to reduce danger from predators, maintain body temperature, and facilitate rapid growth.
Researchers have found evidence of a venom delivery apparatus in an extinct mammal, Bisonalveus browni, dating back 60 million years. The discovery suggests that mammals have evolved more flexible venom systems than previously thought.
The National Human Genome Research Institute (NHGRI) has selected 13 new targets for a large-scale sequencing program, including mammals and non-mammalian organisms. The program aims to gain insights into the biological processes at work in human health and illness by comparing genomes across species.
Turtles have a natural mechanism to shut off energy-utilizing activities during anoxia, unlike humans. The discovery reveals potential targets for improving outcomes of cerebral stroke and cardiac infarct, as well as developing better anesthetics.
Researchers found evidence of the first elephant shrews' presence in North America, suggesting a greater animal migration than previously thought. This discovery has significant implications for our understanding of mammalian evolution and the history of continental breakups.
Paleontologists discovered a prehistoric jawbone that suggests the transformation of bones from the jaw into middle ear bones occurred at least twice in living mammal lines. The evidence supports independent origins of this adaptation in monotremes and placentals, contradicting previous doubts.
Researchers propose a new naming system for bird neurosystems, revealing similarities to mammalian brains. The revised nomenclature reflects recent discoveries in neural processing and behavior, highlighting the cognitive abilities of birds comparable to those of mammals.
Tributyltin oxide (TBT) affects the mechanical activity of outer hair cells, which boost incoming sound energy to inner hair cells. The study found rapid and profound effects of TBT on outer hair cell membrane chloride ion exchange.
A DNA enzyme found in some animals can repair damage caused by UV light, protecting against skin cancer. Researchers discovered this enzyme helps defend against non-melanoma skin cancer in mice with the transgene.
The chicken genome sequence has revealed significant insights into the evolutionary history of mammals and birds. The study found that about 60% of protein-coding genes in chickens have counterparts in humans, highlighting the shared genetic mechanisms underlying various biological processes.
The newly published chicken genomic sequence provides significant information on vertebrate evolution, revealing a clade of at least 9,600 avian species. The analysis also sheds light on the unusual genomic organization of chickens, including large variability in chromosome size and germline mutations.
Researchers successfully reconstructed parts of the genome of a common mammalian ancestor using computerized paleogenomics, achieving an accuracy rate of 98%. This achievement provides a valuable window into the evolution of DNA in placental mammals.
The coelacanth, an ancient fish with unchanged physical features since 360 million years ago, has a sequenced genome that reveals its slow evolution and genetic similarities with land animals. The genome analysis may hold the key to understanding how life transitioned from water to land.
A recent study by a University of Nevada researcher suggests that glucose levels in female mammals may influence the sex of their offspring, challenging a long-standing hypothesis in evolutionary biology. The study's findings have significant implications for wildlife conservation and agriculture production.
A study published in Vision Research found that the size of animals' eyes is linked to their body weight, with larger animals having bigger eyes on average. However, when broken down into smaller groups, such as birds and primates, eye size becomes more complicated and varies greatly.
Researchers at Duke University Medical Center found that flies have distinct combinations of bitter-sensitive nerve cells on their tongue, allowing them to discern among different bitter tastes. This unique ability might enable flies to select the best food item among multiple suboptimal choices.
Scientists discovered that the Sirt1 mammalian gene promotes fat mobilization in mice, revealing a potential molecular link between calorie restriction and longevity. The study suggests that mimicking this effect with a drug could lead to health benefits without dieting.
A team of researchers from the University of Washington has identified a gene, ZFP145, that is linked to sperm-producing stem cells in mammals. The study found that this gene plays a crucial role in the decision-making process of these cells, and its mutation can lead to infertility.
A team of scientists has successfully achieved the first live births of killer whales through artificial insemination. The study, led by Dr. Todd R. Robeck, used genome resource banking and artificial insemination to store sperm from male orcas for later use. This breakthrough may help maintain genetic diversity in captive marine mammals.
A team of researchers found that certain mammals in the Arctic, including rodents, retained a regular sleep-wake cycle despite 82 days of continuous daylight or darkness. The study suggests that the animals may have used external environmental clues to adapt their biological clocks.
Researchers found that African mole-rat eyes have anatomically well-developed retinas and a surprisingly high proportion of cones, which is unusual for blind animals. The density of rods, used for night vision, is also lower than expected in subterranean mammals.
Researchers investigated how small mammals use crossing structures built across the Trans-Canada Highway, finding that small covered culverts offer protection from other animals and are a cost-effective mitigation strategy. The study's findings have already influenced road construction plans, highlighting the importance of conservation...
A research team led by Dr. Howard Lipshitz discovered that a protein linked to mammalian embryo implantation also plays a role in tumour metastasis in fruit fly development. The study found a surprising level of similarity between the proteins in flies and mammals, with potential implications for understanding human disease.
Researchers at Massachusetts General Hospital developed a strain of mice with the c. elegans gene fat-1, which converts omega-6 acids to omega-3s. The transgenic mice produce high levels of omega-3 fatty acids, opening up possibilities for farm animals that naturally produce omega-3 rich food products.
A new discovery of fossil mammals in Ethiopia's highlands sheds light on the evolution of African mammals during a long-standing gap in scientists' understanding. The findings, reported in Nature, show that mammals continued to evolve and produce new species on the isolated continent of Afro-Arabia.
Researchers at the University of Illinois discovered that the timeless gene is essential for regulating the 24-hour circadian rhythm in mammals. Blocking its functional ability disrupts the clock's activity and leads to an uncoupling effect, where other clock genes are no longer able to function properly.
Research reveals that the removal of great whales from the North Pacific Ocean led to a domino effect of ecosystem impacts. Killer whales preyed on other marine mammals, causing devastating effects on ecosystems.
Researchers at UC San Diego discovered that a protein essential for fruit fly embryonic development also plays a crucial role in mammalian wound healing. The study reveals that the loss of this protein causes skin cells to bunch up and stall, leading to slower wound healing rates.
A recent study found that monogamous mammals are more likely to die out due to factors such as population isolation and smaller harems, which can lead to lower male populations and reduced ability to detect approaching hunters. Conservation efforts may need to be targeted towards these species to save them from extinction.
Researchers found hibernating mammals, like ground squirrels, have superior tolerance to extended cold storage. This could lead to new methods for preserving human organs, reducing damage from transportation and storage.
Researchers from the University of Washington and Southern Methodist University conclude that climate change, not humans, was responsible for the extinction of Pleistocene mammals in the New World. The study found no evidence linking Clovis people to the extinctions, contradicting previous 'overkill' hypothesis.
A new study suggests that the brain's language centers may be identified using the genetic expression of certain brain receptors in vocal-learning birds and mammals. The research, led by neurobiologist Erich D. Jarvis, reveals a highly specialized pattern in the genetic expression of these receptors in songbirds capable of vocal learning.
A new study reveals that the human brain can distinguish between thousands of chemicals using a 'fingerprint' pattern, while another discovery sheds light on pheromone-detecting neurons in mice that identify potential mates and social status. These findings may also aid in understanding animal communication and behavior.
A new study published in Nature reveals that all of Madagascar's living Carnivora descended from a single species that dispersed from Africa to the island. The findings refute two previously accepted models for mammal colonization and provide further evidence that lemurs also colonized the island in a single event.
Scientists discovered that early mammals used epipubic bones to stiffen their bodies during trotting steps, allowing for increased mobility and locomotor efficiency. This finding suggests that the development of these bones contributed significantly to the evolution of mammals.
Researchers have identified several genes necessary for fat accumulation in nematode worms, which are also present in humans. These findings provide a crucial platform to rapidly identify key proteins regulating fat formation, potentially leading to new therapies for obesity and diabetes.
Scientists study emesis in genetically engineered mice lacking specific PDE4 subtypes and infer that inhibition of PDE4D mediates nausea. The discovery could lead to the development of selective PDE4 inhibitors with anti-inflammatory effects, reducing side effects in humans.
Researchers at Johns Hopkins Medicine discovered that human Tsix is expressed only on the inactive X chromosome, contradicting previous findings in mice. The study suggests an alternative mechanism for X chromosome regulation and shifts the focus away from the Tsix gene.
Wild meat harvesting is a major threat to threatened species, with big mammals and conspicuous birds being most at risk. Conservation biologists and organizations must work together to address poverty and unmanaged wildlife use to mitigate overhunting.
A study suggests that the global extinction crisis is more severe than previously thought, with over 50% of declining mammal species losing historic ranges. Population extinctions are concentrated in densely populated areas, such as Southeast Asia and Eastern states.
A new study published in Science supports the idea that Asia was the center of origin for key groups of modern mammals, including primates and hooved mammals. The research allows paleontologists to compare fossil sequences from Asia, Europe, and North America during a dramatic period in Earth's history.
A new study maps prime regions for plant-eating mammals, revealing areas with high conservation value. The researchers predict that less than 1.2% of the earth's surface will support uniquely diverse grazing ecosystems by 2025.
The study resolves placental mammals into four major groups, revealing a common ancestor in Gondwana. Afrotheria is the oldest group, with some orders never leaving Africa, and Xenartha populations South America.
A new study by Cardillo and Bromham found that medium-sized mammals were not at greater risk of extinction, contrary to the widely accepted theory. Instead, small mammal species are the least vulnerable to extinction due to high population densities and reproductive rates.