A recent study conducted at Cincinnati Children's Hospital Medical Center found that approximately one in five mothers who visited the pediatric emergency department or a well-child clinic had depression. The study also revealed that 76% of these mothers reported difficulty caring for their children due to their depressive symptoms.
Researchers linked poorly controlled hypertension with a higher risk of depression in patients. The study highlights the importance of treating depression to prevent poor blood pressure control and related health risks.
Researchers are investigating the effectiveness of St. John's wort and citalopram in treating minor depression, a common disorder that can impair daily life and increase the risk of major depression. The study aims to provide evidence-based treatment recommendations for primary care clinicians.
AstraZeneca has submitted an application to the European Health Authorities for a new indication for Seroquel in treating manic episodes associated with bipolar disorder. The company's clinical trial programme showed strong and positive results, confirming Seroquel as an ideal first-line agent for this condition.
Researchers found depression before surgery significantly increased hospitalization for cardiac reasons six months post-operative, with patients experiencing prolonged surgical pain and failure to return to normal activities. Depression also persisted post-surgery, often unrecognized and untreated.
Research by Dr. Karen Hjerl and colleagues found that depression before diagnosis may boost the risk of death for women with advanced breast cancer, but not those in early stages. The study used Danish national health registries to analyze data from 20,593 women.
A Stanford study found a significant link between depression and chronic pain, suggesting that pain may guide doctors to effective treatments for depressed patients. The research also indicates that continuous pain increases the likelihood of major depressive disorder diagnosis.
A recent study published in Psychosomatic Medicine found that depression is more deadly for men over 70 than women, despite occurring less frequently. Depression was associated with increased mortality rates in men after accounting for other factors, while chronic and remitted depression had no significant impact on mortality rates.
A study of 39 hepatitis C patients found that 33% developed interferon-induced major depression, but 84% improved with antidepressant treatment. The research challenges the common practice of discontinuing interferon therapy for depressed patients.
A study by Wim J. Riedel and colleagues found that tryptophan depletion can impair learning and memory, cause depressed mood, and induce mood depression in individuals with a family history of depression. The effects typically last for 24 hours.
Researchers found that teen-age girls with a history of depression display enhanced alpha activity in the brain, indicating a consistent abnormality. A family history of alcoholism is associated with beta activity in a different region, suggesting potential biological markers for liability to alcoholism or depression.
Researchers found that depression is influenced by additive genetic effects on temperament dimensions, which interact with individual environmental experiences. People predisposed to harm avoidance or high reward dependence are more likely to develop depression.
A recent study found that depression one month after coronary artery bypass surgery is a significant risk factor for continued cardiac problems. The research suggests that evaluating patients for depression after surgery and providing treatment may enhance long-term outcomes.
A study by UT Southwestern researcher Dr. John Rush and colleagues found that long-term treatment of chronic depression can result in sustained psychosocial benefits. The therapy showed significant improvement rates among patients taking Zoloft, with only 6% relapse rate compared to 23% for the placebo group.
A recent study published in Psychosomatic Medicine reveals that heart transplant patients with depression are at a higher risk of mortality compared to those without depression. The study found significant correlations between depression and poor post-operative survival in ischemic disease patients.
A new generation antipsychotic quetiapine, combined with mood stabilizers, shows improved efficacy in treating manic symptoms of bipolar disorder. The study results indicate that more patients experience full resolution of manic symptoms when treated with quetiapine.
Renowned researcher Lewinsohn has made significant contributions to understanding depression in adolescents, adults, and older individuals. His work on treatment interventions continues to be widely used globally.
The U-M Depression Center will expand outreach activities, automate treatment reporting, and coordinate care through trained specialists to improve depression treatment. The gift also enables the development of strategies for improving treatment adherence, a key factor in successful treatment outcomes.
A study published in Molecular Psychiatry found that specific genetic markers on chromosome 2 are associated with severe depression in women, but not in men. This discovery suggests important differences in the molecular basis of clinical depression between sexes, which may contribute to varying treatment responses and symptoms.
Researchers investigate how reducing serotonin levels affects people with and without depression. The study uses tryptophan depletion to temporarily lower serotonin levels in participants, aiming to discover new ways to predict who is at risk for major depression and when treatment can be safely discontinued.
A study by the American Academy of Neurology found that individuals with depression are more likely to develop Parkinson's disease than those without depression. The researchers suggest that low levels of serotonin in the brain may contribute to both depression and Parkinson's disease, increasing the risk of developing the latter.
Stanford researchers have established a link between creative genius and mental illness, with healthy artists showing more similarities in personality to individuals with manic depression. Emotional range was found to be a key factor in this relationship.
Duke University researchers found depression to be a significant predictor of worse quality of life and perceived shortness of breath in patients awaiting lung transplantation. The study suggests that treating depression could improve outcomes after lung transplantation, which could benefit patients with severe lung disease like COPD.
The USPSTF recommends screening all adults for depression, as five percent to nine percent of adult patients in primary care settings suffer from the condition. Depression can be treated with counseling, medications, or both, reducing health care utilization and costs associated with lost workdays.
Research suggests that defects in 'orphan' inositol polyphosphates may contribute to diseases such as manic depression and cancer. Dr. York's work identifies biological roles for these molecules and provides a basis for designing more specific drugs with fewer side effects.
A large clinical trial found St. John's wort to be no more effective than placebo in treating moderately severe major depression. Researchers tested the supplement against the antidepressant sertraline and concluded that patients with moderate to severe depression should not self-medicate with St. John's wort.
A study suggests that a high intake of DHA may reduce the risk of postpartum depression. Babies who receive sufficient levels of DHA also benefit from improved neurological development. The American Chemical Society research aims to raise awareness about the importance of nutrition for mothers and their babies.
A study by Pitt researchers found that men and women have different genetic markers associated with severe depression, which may lead to better diagnosis and treatment strategies. The findings suggest that sex-specific genes for recurrent major depression may be the rule rather than the exception.
A recent study found that postpartum fatigue is significantly linked to postpartum depression, with women reporting symptoms after just 28 days, highlighting the need for screening tools and self-care support
A recent study found that 51% of pregnant minority women experienced depression, with levels similar between African-American and Hispanic groups. The research highlights the need for healthcare providers to identify and address social support issues in these vulnerable populations.
A study published in the American Journal of Psychiatry found that nearly all antidepressant trials exclude patients with mild depression, anxiety disorders, or other psychiatric problems. This limits the generalizability of trial results and may lead to unjustified exposure of risks and side effects.
A multicentric study has identified an excess of allele1 for the GABRA3 gene in patients with bipolar disorder. This finding suggests a potential link between genetic variations and the development of manic-depressive illness.
A study of 78 older adults found that chronic, sub-clinical mild depression can suppress immune systems, leading to poorer responses to infections and diseases. The findings suggest that early detection and treatment of even mild depression may be crucial for better health in older adults.
Elderly women with depression are nearly twice as likely to develop heart failure over a 14-year period. Depression also increases the risk of physical illnesses like hypertension and diabetes that contribute to heart disease.
A University of Illinois study suggests that repetitive transcranial magnetic stimulation (rTMS) is a promising alternative to electroconvulsive therapy (ECT) for treating severe depression, with better tolerability and fewer side effects. rTMS showed significant improvement in depression scores, with a 55% reduction in the treatment g...
A study found significant cultural differences in depression attitudes between Protestants and Jews, particularly among Jewish men who were less likely to use alcohol as an escape from depression. The research also revealed gender differences in attitudes towards alcohol and suicide.
Scientists at Johns Hopkins Medicine found that panic disorder and manic depressive (bipolar) illness are likely related genetically and share a common cause. The study analyzed 203 families with bipolar disorder and identified symptoms of major mood disorders in relatives, showing a strong genetic link between the conditions.
A multi-site clinical trial found that citalopram, a popular adult anti-depressant, may help relieve suffering in children and adolescents with depression. The study showed significant improvement in mood among patients receiving the drug compared to those taking a placebo.
A new study aims to determine the effectiveness of drug therapy, psychotherapy, or a combination in treating major depression in teenagers. The study, administered by Northwestern University Medical School, will enroll participants between 12-17 years old with clinician-diagnosed depression.
A new study found that Topamax significantly reduced the severity of manic symptoms in patients with bipolar disorder, with 70% experiencing improvement. The medication was well-tolerated, with no significant weight gain and fewer side effects compared to traditional treatments.
A study found that depressed patients are more than twice as likely to die or be readmitted for cardiac causes after CABG surgery. Depression is also associated with a significant independent risk of adverse cardiac events.
A new study found that children from poor families with depressed mothers experience delays in cognitive and motor development, while middle-class households offer some protection. The effects of maternal depression on boys and girls differ, with moderate depression in affluent families resulting in lower cognitive scores.
Researchers found depressed heart attack survivors are less likely to adopt healthier behaviors, with those perceiving poor physical health showing the most resistance. This study emphasizes the importance of addressing post-heart attack depression and exploring biological markers associated with it.
Johns Hopkins faculty members Kay Redfield Jamison and Geraldine Seydoux have been awarded the MacArthur Foundation's 'genius' award for their innovative research in psychology and biology. Their work has significantly advanced understanding of mental health treatment, psychiatric disorders, and biological development.
Researchers found four mental health factors beyond depression that predict suicidal behavior in individuals with panic disorder, including overall anxiety level and fear of losing one's mind. The study suggests that these additional factors contribute to the development of suicidal thoughts, even when depression is present.
A study found that depression is associated with self-reported hypertension, but this relationship does not exist when blood pressure is measured clinically. Lifestyle factors such as obesity, sedentary lifestyles, and stress are more strongly linked to high blood pressure.
A new study at Duke University Medical Center reveals that depressed heart failure patients are twice as likely to die or be re-admitted to hospital within three months and one year. The researchers recommend testing for depression in all CHF patients to improve outcomes.
A study found that physical maladies such as diminished energy and sleep disturbances can reliably indicate depression in the elderly. However, symptoms like work inhibition and weight loss are poor discriminators of depression in older adults due to factors like aging process and ill health.
Researchers found that paroxetine, a selective serotonin reuptake inhibitor, was more effective than imipramine or placebo in reducing depression symptoms and improving patient moods. The study involved 275 patients aged 12-18 with major depression.
A new analysis of 27 studies reveals that depression is associated with increased numbers, severity and ratings of diabetes complications. The study suggests a complex relationship between depression and diabetes, where underlying mechanisms may be influenced by biological, social and psychological variables.
A new report reveals that bipolar disorder costs the UK over £2 billion annually, with up to 85% associated with lost productivity. The study suggests Risperdal as an effective treatment for acute bipolar mania, improving symptoms by at least 50% in patients.
A strong association has been found between depression and osteoporosis, with depressed individuals experiencing lower bone mineral density. Research suggests that depression may contribute to hormonal abnormalities leading to bone loss and changes in body composition.
A landmark survey shows that patients with major depression often feel their illness isn't under complete control and experience few quality-of-life improvements. The study highlights a significant communication gap between primary care physicians and patients, leading to inadequate treatment and side effect management.
A large-scale study has found lamotrigine to be safe and effective in preventing episodes of mood swings in patients with rapid-cycling bipolar disorder. The study, published in Journal of Clinical Psychiatry, showed that 41% of patients who received lamotrigine remained stable without relapse for six months, compared to 26% on placebo.
A new UCLA study reveals an inverse relationship between depression and strong ties to the African American community, independent of demographic and health factors. Women with strong ethnic identity experienced lower levels of depression and less excess weight.
Researchers at the University of Colorado at Boulder found that patients who received medication and a family-focused treatment program had fewer episodes of the disease, with longer delays before relapses. The study suggests that positive family interaction can help limit relapse rates.
Research at the University of Michigan found a 30% higher concentration of signaling cells in people with bipolar disorder, which could explain and treat manic depression. The discovery highlights the disorder's genetic and biological roots, offering new avenues for understanding and treatment.
A new study suggests that regular exercise is as effective as antidepressants in reducing depression rates. Participants who exercised regularly showed lower relapse rates, even six months after treatment ended.
Researchers have discovered a biological marker associated with depression in children, who produce less growth hormone than normal peers when given a specific hormone. This finding could give doctors an early warning system to treat children at risk for major depression before they develop the illness.
A study of nearly 2,000 adults aged 18-90 found that higher education delayed the onset of depression by approximately ten years. This is because better physical health helps mitigate depression risk.